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The map label for this gene is intZ [H]

Identifier: 114332212

GI number: 114332212

Start: 2378101

End: 2379303

Strand: Direct

Name: intZ [H]

Synonym: Neut_2252

Alternate gene names: 114332212

Gene position: 2378101-2379303 (Clockwise)

Preceding gene: 114332211

Following gene: 114332213

Centisome position: 89.37

GC content: 58.02

Gene sequence:

>1203_bases
ATGCTGACCGATACCAAGCTGCGCAATCTCAAGCCCAGGGACAAACTCTACAAAGTGAATGACCGGGAAGGTCTCTATGT
GGCAGTGACTCCAGCCGGCTCCATCTCGTTCCGTTACAACTACTCAATCAACGGTCGGCAGGAGACCATCACCTTTGGGC
GTTATGGTGTCGGTGGCATCACCCTGGCCGAAGCCCGCGAGCTGTTGGGTGACGCCAAGAAGATGGTTGCGGCGGGCAAG
TCGCCGGCCAAGGAGAAAGCCCGAGACAAGGCGCGGGTGAAAGATGCAGAGACGTTCGGTGCCTGGGCGGAGAAGTGGCT
GCGTGGCTACCAGATGGCCGACTCCACCCGCGATATGCGCCGCTCGGTTTATGAGCGTGAGCTGAAGCCGAAATTCAGCA
ATCAGAAGCTGGTGGAGATCACCCACGAAGACTTGCGGGCGCTGGCTGATGCCATTGTTGAGCGAGGCGCACCGGCCACC
GCCGTTCATGTGCGTGAAATCGTGTTGCAGGTATTTCGCTGGGCCATCGAGCGTGGGCAGAAGGTCGAAAACCCGGCAGA
ACTGGTGCGCCCAACAAGCATCGCTCGATTCGAGCCACGTGACCGAGCGTTGACGCCAGAAGAAATTGGGCTGATGTACC
AGTACATGGAGCGAGTGGGCACAAGCCCAACAAACCGTGCGGCGGCCAAGCTGTTATTGCTGACGATGGTGCGCAAGAGC
GAGCTGACCAATGCGACCTGGAGCGAGATCAATTTCAGCGAAGCGTTGTGGACGATTCCAAAGGAGCGGATGAAACGCCG
TAACCCGCACCTGGTATTTCTGTCCCAGCAGGCTCTGGATATTTTCATTGCCATGAAAACCTTTGCCGGTGGTTCCGACT
TCGTTTTGCCATCACGGTACGACTCGGATGCGCCGATGAGCGCTGCCACACTTAACCAGGTGCTGACGCTGACTTACAAG
GCGGCGCAGAAAGATGGGAAGTCACTTACCAAGTTCGGACCGCATGATTTGCGGCGCACAGCCAGCACGCTGTTGCATGA
GGCCGGCTACAACACCGACTGGATCGAGAAGTGCCTGGCGCACGAGCAGAAGGGCGTGAGGGCTGTCTACAACAAGGCTG
AGTACCGCGAGCAGCGGGCGGCGATGTTGCAGGATTGGGCCGATATGATTGATGAGTGGACTTCGGGAGGCAGTAAGGGT
TGA

Upstream 100 bases:

>100_bases
CATGGTATTAATATTCTATAAGTTACTGTTTCGTAAGAAAAAATACGATAAATTCGAGATTTTTTCAGCATGGTATCGGA
GACGAAGAAGGACAAGGTAC

Downstream 100 bases:

>100_bases
TGTTTTTGCTATCTTTGATAGCATTGAAGTTGATGCCGTGAATTTATAAATAAGGCCGCCATTGGCATCGGGCAGGTCAA
TTACCGATTAGCTGCTTCGC

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MLTDTKLRNLKPRDKLYKVNDREGLYVAVTPAGSISFRYNYSINGRQETITFGRYGVGGITLAEARELLGDAKKMVAAGK
SPAKEKARDKARVKDAETFGAWAEKWLRGYQMADSTRDMRRSVYERELKPKFSNQKLVEITHEDLRALADAIVERGAPAT
AVHVREIVLQVFRWAIERGQKVENPAELVRPTSIARFEPRDRALTPEEIGLMYQYMERVGTSPTNRAAAKLLLLTMVRKS
ELTNATWSEINFSEALWTIPKERMKRRNPHLVFLSQQALDIFIAMKTFAGGSDFVLPSRYDSDAPMSAATLNQVLTLTYK
AAQKDGKSLTKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQKGVRAVYNKAEYREQRAAMLQDWADMIDEWTSGGSKG

Sequences:

>Translated_400_residues
MLTDTKLRNLKPRDKLYKVNDREGLYVAVTPAGSISFRYNYSINGRQETITFGRYGVGGITLAEARELLGDAKKMVAAGK
SPAKEKARDKARVKDAETFGAWAEKWLRGYQMADSTRDMRRSVYERELKPKFSNQKLVEITHEDLRALADAIVERGAPAT
AVHVREIVLQVFRWAIERGQKVENPAELVRPTSIARFEPRDRALTPEEIGLMYQYMERVGTSPTNRAAAKLLLLTMVRKS
ELTNATWSEINFSEALWTIPKERMKRRNPHLVFLSQQALDIFIAMKTFAGGSDFVLPSRYDSDAPMSAATLNQVLTLTYK
AAQKDGKSLTKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQKGVRAVYNKAEYREQRAAMLQDWADMIDEWTSGGSKG
>Mature_400_residues
MLTDTKLRNLKPRDKLYKVNDREGLYVAVTPAGSISFRYNYSINGRQETITFGRYGVGGITLAEARELLGDAKKMVAAGK
SPAKEKARDKARVKDAETFGAWAEKWLRGYQMADSTRDMRRSVYERELKPKFSNQKLVEITHEDLRALADAIVERGAPAT
AVHVREIVLQVFRWAIERGQKVENPAELVRPTSIARFEPRDRALTPEEIGLMYQYMERVGTSPTNRAAAKLLLLTMVRKS
ELTNATWSEINFSEALWTIPKERMKRRNPHLVFLSQQALDIFIAMKTFAGGSDFVLPSRYDSDAPMSAATLNQVLTLTYK
AAQKDGKSLTKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQKGVRAVYNKAEYREQRAAMLQDWADMIDEWTSGGSKG

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=404, Percent_Identity=36.1386138613861, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788974, Length=416, Percent_Identity=31.0096153846154, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1788690, Length=399, Percent_Identity=27.3182957393484, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45330; Mature: 45330

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDTKLRNLKPRDKLYKVNDREGLYVAVTPAGSISFRYNYSINGRQETITFGRYGVGGI
CCCCCCHHCCCCHHHCEEECCCCCEEEEEECCCCEEEEEEEEECCCEEEEEECCCCCCCE
TLAEARELLGDAKKMVAAGKSPAKEKARDKARVKDAETFGAWAEKWLRGYQMADSTRDMR
EHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVYERELKPKFSNQKLVEITHEDLRALADAIVERGAPATAVHVREIVLQVFRWAIERGQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KVENPAELVRPTSIARFEPRDRALTPEEIGLMYQYMERVGTSPTNRAAAKLLLLTMVRKS
CCCCHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELTNATWSEINFSEALWTIPKERMKRRNPHLVFLSQQALDIFIAMKTFAGGSDFVLPSRY
HCCCCCHHHCCHHHHHHHCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
DSDAPMSAATLNQVLTLTYKAAQKDGKSLTKFGPHDLRRTASTLLHEAGYNTDWIEKCLA
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
HEQKGVRAVYNKAEYREQRAAMLQDWADMIDEWTSGGSKG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLTDTKLRNLKPRDKLYKVNDREGLYVAVTPAGSISFRYNYSINGRQETITFGRYGVGGI
CCCCCCHHCCCCHHHCEEECCCCCEEEEEECCCCEEEEEEEEECCCEEEEEECCCCCCCE
TLAEARELLGDAKKMVAAGKSPAKEKARDKARVKDAETFGAWAEKWLRGYQMADSTRDMR
EHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVYERELKPKFSNQKLVEITHEDLRALADAIVERGAPATAVHVREIVLQVFRWAIERGQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KVENPAELVRPTSIARFEPRDRALTPEEIGLMYQYMERVGTSPTNRAAAKLLLLTMVRKS
CCCCHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELTNATWSEINFSEALWTIPKERMKRRNPHLVFLSQQALDIFIAMKTFAGGSDFVLPSRY
HCCCCCHHHCCHHHHHHHCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
DSDAPMSAATLNQVLTLTYKAAQKDGKSLTKFGPHDLRRTASTLLHEAGYNTDWIEKCLA
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
HEQKGVRAVYNKAEYREQRAAMLQDWADMIDEWTSGGSKG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]