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The map label for this gene is dnaQ [H]

Identifier: 114332140

GI number: 114332140

Start: 2305280

End: 2305984

Strand: Reverse

Name: dnaQ [H]

Synonym: Neut_2175

Alternate gene names: 114332140

Gene position: 2305984-2305280 (Counterclockwise)

Preceding gene: 114332141

Following gene: 114332138

Centisome position: 86.66

GC content: 47.8

Gene sequence:

>705_bases
ATGCGCTACGTCTTTCTTGATACTGAAACGACCGGCCTGGATCCGGCGCTGGGGCACCGTATTGTCGAAATAGCAGCGGT
AGAAGTATGTAACCGACGTTCGACCGGCCGTCATTTTCATCGTTATCTCAATCCTGGGCGGGAGAGTGATGAGGGCGCGC
TGCGGGTGCATGGACTGAGCCGGGAATTCTTGCAGGATAAACCTGCTTTCCAGGAGATTTGTAGCGAGTTTTTGGAATTC
ATAGAAGATGCCGAAATTCTTATTCATAATGCGCCATTTGACGTAGGTTTCATCAATCGTGAACTTGGTTTGATCCGGTT
GGAACCCATGCATAATTATTGCCTGCAGATTGTTGATACGTTGATGTTGGCAAAGGAGCTGCATCCAGGTAAACGAAACA
ATCTGGATGCGTTATGTGAGCGGTATCAGATTGATAACGCTCACAGAACACTGCATGGTGCTTTGCTGGATGCTGAATTG
CTGGCCGAAGTTTATCTGGCAATGACGCGCGGCCAGGAAAGTTTGCTGATGGAGCCGGAAGTTCCAGAAGCAGGGAAGTC
TGGCGATTCAAGGCTACGTGCAACAGAAAATCTTACATTGATCGTTCAGCCCGTCAGCCAAACAGAACTTGAGTTGCATG
ATCGGCTGTTGGAGCGTATTAATACGGAAAGCAAGGGAAATTGTTTATGGAACAGTCAAAATTAA

Upstream 100 bases:

>100_bases
GGGGACATAACGGACATGCAGGTAATGAGCGGGCTGATAGGCTTGCAAATCAGGGAGTGGAATCGGTGTTATCTAAAAAA
GCAGATTGATCGGACAGATT

Downstream 100 bases:

>100_bases
TTTGGAATTCCTTAGGTATGTAGTTTTGTACGAAGCGCCTGGGTTGCCAGTACTTTACCAAAATCCCAGACTGCAGCGGG
GCCCCGATGCGCGCTGGCCA

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRYVFLDTETTGLDPALGHRIVEIAAVEVCNRRSTGRHFHRYLNPGRESDEGALRVHGLSREFLQDKPAFQEICSEFLEF
IEDAEILIHNAPFDVGFINRELGLIRLEPMHNYCLQIVDTLMLAKELHPGKRNNLDALCERYQIDNAHRTLHGALLDAEL
LAEVYLAMTRGQESLLMEPEVPEAGKSGDSRLRATENLTLIVQPVSQTELELHDRLLERINTESKGNCLWNSQN

Sequences:

>Translated_234_residues
MRYVFLDTETTGLDPALGHRIVEIAAVEVCNRRSTGRHFHRYLNPGRESDEGALRVHGLSREFLQDKPAFQEICSEFLEF
IEDAEILIHNAPFDVGFINRELGLIRLEPMHNYCLQIVDTLMLAKELHPGKRNNLDALCERYQIDNAHRTLHGALLDAEL
LAEVYLAMTRGQESLLMEPEVPEAGKSGDSRLRATENLTLIVQPVSQTELELHDRLLERINTESKGNCLWNSQN
>Mature_234_residues
MRYVFLDTETTGLDPALGHRIVEIAAVEVCNRRSTGRHFHRYLNPGRESDEGALRVHGLSREFLQDKPAFQEICSEFLEF
IEDAEILIHNAPFDVGFINRELGLIRLEPMHNYCLQIVDTLMLAKELHPGKRNNLDALCERYQIDNAHRTLHGALLDAEL
LAEVYLAMTRGQESLLMEPEVPEAGKSGDSRLRATENLTLIVQPVSQTELELHDRLLERINTESKGNCLWNSQN

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=238, Percent_Identity=45.7983193277311, Blast_Score=214, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26685; Mature: 26685

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVFLDTETTGLDPALGHRIVEIAAVEVCNRRSTGRHFHRYLNPGRESDEGALRVHGLS
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEECCC
REFLQDKPAFQEICSEFLEFIEDAEILIHNAPFDVGFINRELGLIRLEPMHNYCLQIVDT
HHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCEEEECHHHHHHHHHHHH
LMLAKELHPGKRNNLDALCERYQIDNAHRTLHGALLDAELLAEVYLAMTRGQESLLMEPE
HHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCC
VPEAGKSGDSRLRATENLTLIVQPVSQTELELHDRLLERINTESKGNCLWNSQN
CCCCCCCCCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEECCCCC
>Mature Secondary Structure
MRYVFLDTETTGLDPALGHRIVEIAAVEVCNRRSTGRHFHRYLNPGRESDEGALRVHGLS
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEECCC
REFLQDKPAFQEICSEFLEFIEDAEILIHNAPFDVGFINRELGLIRLEPMHNYCLQIVDT
HHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCEEEECHHHHHHHHHHHH
LMLAKELHPGKRNNLDALCERYQIDNAHRTLHGALLDAELLAEVYLAMTRGQESLLMEPE
HHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCC
VPEAGKSGDSRLRATENLTLIVQPVSQTELELHDRLLERINTESKGNCLWNSQN
CCCCCCCCCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]