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The map label for this gene is oxaA

Identifier: 114332119

GI number: 114332119

Start: 2278723

End: 2280591

Strand: Direct

Name: oxaA

Synonym: Neut_2154

Alternate gene names: 114332119

Gene position: 2278723-2280591 (Clockwise)

Preceding gene: 114332118

Following gene: 114332120

Centisome position: 85.63

GC content: 47.83

Gene sequence:

>1869_bases
ATGGACAATAAAAAAATCGTACTGCTTATCATTTTTTCGACATCGCTACTGTTTTTATGGGATGCATGGGTAAAAGAACA
GGAAAAGTTCAACGCCCCTCCCTCCGTTGTAGCTCAGGCTAATTCCGCAGCCGGAGTCACACAGTCAAAAAATAACGACG
GCCTTCCTATTCCAGGCAGTGAACTCACAGCATCACAAACAGGATCGGATCTGAACGGGATACCTTCAAGTGGAGATACA
GCTGATTCGGTTACCCCACGCCTGTTGCCTTCAGGCGAGCAAATACGTGTCGTCACCGACAAGGTCATTGCAGAAATCGA
CACGATGGGAGGCGATTTACGGCGACTGGAACTACTGCAACAACCTTCTCCTGAAGACGAGAACGTACCTTACTCTCTAT
TGCATAGCGAAGCTTCGCGTACCTATGTCGCACAATCCGGTCTGGTAGGCGAGGGATTGCCTAACCATAAAACGGTTTAT
CAGGTGGAATCAGGCATACGCAACTACGAACTGACTGCCGGCGAGGATAAAGTTGTCATCCGCCTGCTGGCACCTGAAAC
TCAGGGAGTTCAGGTTATAAAAACCTACACCTTTCACCGCGACAGCTACGTAATCGACATCGGCTTCGAGATAGCAAACA
AGAGCGATGCCACAATCCGTCCGTTTGCTTATTTCCAGATGTTGCGTGACGACACTCCGCCACCAGCACACACCATGATG
ATTCGCAGTTTTCTGGGGGCTGCTGTTTACACTGACGAAGAGAAATATCAGAAAATTCCGTTTGATGACCTGGACAAAGG
CAAGACAGATTATCCGGCCAATGCGAACAATGGCTGGATCGCCATGCTGGAACACTATTTCCTGACTGCCTGGTTGCCGC
CACAACAAACACCACGCGAATATTTTGCCAAGCGACAAAGCGATAATCTCTATACAGCCGGGGTAATTGTTCCGGCCGGA
GTTATCACTGCTGGTGAAACTGTTACAACCACCATGCCACTTTATGCAGGTCCGGAAGAGCAAGATAGGCTTGCTGAACT
AGCTCCGGGGCTGGAGCTTACTGTTGATTACGGCTGGCTGACCATGATCGCCAAGCCATTATTCCGTTTACTTTCTTTCT
ACCATTCGTGGACAGGAAACTGGGGAATAGCAATTATCCTTCTGACCATAACCGTCAAGCTGCTGTTCTTCCCGCTATCT
GCGGCCGGCTACCGATCCATGGCAAAATTACGCTTGGTAACGCCCAAGTTGAAGCGTATTCAGGATCAATACAAGGGTGA
TCGGCAGCGCATGCATCAGGCGATGATGGATTTTTATAAAACAGAAAAAATCAACCCGATGGGGGGGTGTTTTCCCATAC
TGGTGCAAATCCCGGTTTTTATTGCGCTGTACTGGACAATACTTGCAGCAGTAGAACTGCGTTACGCTCCTTTTGCACTA
TGGATCACTGATTTATCTTCTCCAGATCCCAAATACCTGCTGCCGGTTCTGCTGGGCATTTCCATGTTTATACAGACCAG
GCTTAATCCGACCCCAACAGATCCAATCCAGGCAAAAATAATGCAAATTATGCCTGTTGCCTTCAGTGCCATTTTCTTCT
TCTTCCCGGCCGGTCTTGTTCTTTATTCCCTGGTCAATAATATTCTGTCAATCGCGCAGCAATGGAAGATTACAAAAATG
TACGGGACTGCCCCCAGTCAAGACGCTCCTGAATCACCCGCTAGTAAAGATGCTCCTGAACTACCCGTCAGTAACCAGGT
TATTAACGATTCAGAAAATACAGAAGCACCTGCCAGTGGTCCGGCTGATAGTCCTAAAAAACCTGTTAACATTCCGAGAA
GAATGCACAAAAGAACGAGAAAGAAATAA

Upstream 100 bases:

>100_bases
TATCCCATAAAACAGCCAATATGCCCATAATAACCAACTTATCTATCATATTCTTAAAGCGTTTTTACTAAAACTTTTCC
GCATCCCCGAGCTTCAAAAA

Downstream 100 bases:

>100_bases
ATATTTATAACTTCAACTGCTCTGTGTCCCTTTTGATAAAGAAGGTATGCAATGCCCTGCCACCTCCTTGGTGAAGAATA
ATGACACCATTGCAGCAATC

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MDNKKIVLLIIFSTSLLFLWDAWVKEQEKFNAPPSVVAQANSAAGVTQSKNNDGLPIPGSELTASQTGSDLNGIPSSGDT
ADSVTPRLLPSGEQIRVVTDKVIAEIDTMGGDLRRLELLQQPSPEDENVPYSLLHSEASRTYVAQSGLVGEGLPNHKTVY
QVESGIRNYELTAGEDKVVIRLLAPETQGVQVIKTYTFHRDSYVIDIGFEIANKSDATIRPFAYFQMLRDDTPPPAHTMM
IRSFLGAAVYTDEEKYQKIPFDDLDKGKTDYPANANNGWIAMLEHYFLTAWLPPQQTPREYFAKRQSDNLYTAGVIVPAG
VITAGETVTTTMPLYAGPEEQDRLAELAPGLELTVDYGWLTMIAKPLFRLLSFYHSWTGNWGIAIILLTITVKLLFFPLS
AAGYRSMAKLRLVTPKLKRIQDQYKGDRQRMHQAMMDFYKTEKINPMGGCFPILVQIPVFIALYWTILAAVELRYAPFAL
WITDLSSPDPKYLLPVLLGISMFIQTRLNPTPTDPIQAKIMQIMPVAFSAIFFFFPAGLVLYSLVNNILSIAQQWKITKM
YGTAPSQDAPESPASKDAPELPVSNQVINDSENTEAPASGPADSPKKPVNIPRRMHKRTRKK

Sequences:

>Translated_622_residues
MDNKKIVLLIIFSTSLLFLWDAWVKEQEKFNAPPSVVAQANSAAGVTQSKNNDGLPIPGSELTASQTGSDLNGIPSSGDT
ADSVTPRLLPSGEQIRVVTDKVIAEIDTMGGDLRRLELLQQPSPEDENVPYSLLHSEASRTYVAQSGLVGEGLPNHKTVY
QVESGIRNYELTAGEDKVVIRLLAPETQGVQVIKTYTFHRDSYVIDIGFEIANKSDATIRPFAYFQMLRDDTPPPAHTMM
IRSFLGAAVYTDEEKYQKIPFDDLDKGKTDYPANANNGWIAMLEHYFLTAWLPPQQTPREYFAKRQSDNLYTAGVIVPAG
VITAGETVTTTMPLYAGPEEQDRLAELAPGLELTVDYGWLTMIAKPLFRLLSFYHSWTGNWGIAIILLTITVKLLFFPLS
AAGYRSMAKLRLVTPKLKRIQDQYKGDRQRMHQAMMDFYKTEKINPMGGCFPILVQIPVFIALYWTILAAVELRYAPFAL
WITDLSSPDPKYLLPVLLGISMFIQTRLNPTPTDPIQAKIMQIMPVAFSAIFFFFPAGLVLYSLVNNILSIAQQWKITKM
YGTAPSQDAPESPASKDAPELPVSNQVINDSENTEAPASGPADSPKKPVNIPRRMHKRTRKK
>Mature_622_residues
MDNKKIVLLIIFSTSLLFLWDAWVKEQEKFNAPPSVVAQANSAAGVTQSKNNDGLPIPGSELTASQTGSDLNGIPSSGDT
ADSVTPRLLPSGEQIRVVTDKVIAEIDTMGGDLRRLELLQQPSPEDENVPYSLLHSEASRTYVAQSGLVGEGLPNHKTVY
QVESGIRNYELTAGEDKVVIRLLAPETQGVQVIKTYTFHRDSYVIDIGFEIANKSDATIRPFAYFQMLRDDTPPPAHTMM
IRSFLGAAVYTDEEKYQKIPFDDLDKGKTDYPANANNGWIAMLEHYFLTAWLPPQQTPREYFAKRQSDNLYTAGVIVPAG
VITAGETVTTTMPLYAGPEEQDRLAELAPGLELTVDYGWLTMIAKPLFRLLSFYHSWTGNWGIAIILLTITVKLLFFPLS
AAGYRSMAKLRLVTPKLKRIQDQYKGDRQRMHQAMMDFYKTEKINPMGGCFPILVQIPVFIALYWTILAAVELRYAPFAL
WITDLSSPDPKYLLPVLLGISMFIQTRLNPTPTDPIQAKIMQIMPVAFSAIFFFFPAGLVLYSLVNNILSIAQQWKITKM
YGTAPSQDAPESPASKDAPELPVSNQVINDSENTEAPASGPADSPKKPVNIPRRMHKRTRKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=566, Percent_Identity=35.1590106007067, Blast_Score=368, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24662345, Length=233, Percent_Identity=28.3261802575107, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356443, Length=233, Percent_Identity=28.3261802575107, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_NITEC (Q0AE56)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748341.1
- ProteinModelPortal:   Q0AE56
- SMR:   Q0AE56
- STRING:   Q0AE56
- GeneID:   4272942
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2154
- NMPDR:   fig|335283.3.peg.188
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- PhylomeDB:   Q0AE56
- ProtClustDB:   CLSK585296
- BioCyc:   NEUT335283:NEUT_2154-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 69255; Mature: 69255

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15d151c4)-; HASH(0x165b34dc)-; HASH(0x165adc88)-; HASH(0x165adac0)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKKIVLLIIFSTSLLFLWDAWVKEQEKFNAPPSVVAQANSAAGVTQSKNNDGLPIPGS
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
ELTASQTGSDLNGIPSSGDTADSVTPRLLPSGEQIRVVTDKVIAEIDTMGGDLRRLELLQ
CCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHH
QPSPEDENVPYSLLHSEASRTYVAQSGLVGEGLPNHKTVYQVESGIRNYELTAGEDKVVI
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHEECCCCCCEEEECCCCEEEE
RLLAPETQGVQVIKTYTFHRDSYVIDIGFEIANKSDATIRPFAYFQMLRDDTPPPAHTMM
EEECCCCCCCEEEEEEEEECCCEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHH
IRSFLGAAVYTDEEKYQKIPFDDLDKGKTDYPANANNGWIAMLEHYFLTAWLPPQQTPRE
HHHHHHHHEECCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCHHH
YFAKRQSDNLYTAGVIVPAGVITAGETVTTTMPLYAGPEEQDRLAELAPGLELTVDYGWL
HHHHCCCCCEEEEEEEECCCEEECCCEEEEEECCCCCCCHHHHHHHHCCCCEEEECHHHH
TMIAKPLFRLLSFYHSWTGNWGIAIILLTITVKLLFFPLSAAGYRSMAKLRLVTPKLKRI
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
QDQYKGDRQRMHQAMMDFYKTEKINPMGGCFPILVQIPVFIALYWTILAAVELRYAPFAL
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
WITDLSSPDPKYLLPVLLGISMFIQTRLNPTPTDPIQAKIMQIMPVAFSAIFFFFPAGLV
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LYSLVNNILSIAQQWKITKMYGTAPSQDAPESPASKDAPELPVSNQVINDSENTEAPASG
HHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC
PADSPKKPVNIPRRMHKRTRKK
CCCCCCCCCCCHHHHHHHHCCH
>Mature Secondary Structure
MDNKKIVLLIIFSTSLLFLWDAWVKEQEKFNAPPSVVAQANSAAGVTQSKNNDGLPIPGS
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
ELTASQTGSDLNGIPSSGDTADSVTPRLLPSGEQIRVVTDKVIAEIDTMGGDLRRLELLQ
CCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHH
QPSPEDENVPYSLLHSEASRTYVAQSGLVGEGLPNHKTVYQVESGIRNYELTAGEDKVVI
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHEECCCCCCEEEECCCCEEEE
RLLAPETQGVQVIKTYTFHRDSYVIDIGFEIANKSDATIRPFAYFQMLRDDTPPPAHTMM
EEECCCCCCCEEEEEEEEECCCEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHH
IRSFLGAAVYTDEEKYQKIPFDDLDKGKTDYPANANNGWIAMLEHYFLTAWLPPQQTPRE
HHHHHHHHEECCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCHHH
YFAKRQSDNLYTAGVIVPAGVITAGETVTTTMPLYAGPEEQDRLAELAPGLELTVDYGWL
HHHHCCCCCEEEEEEEECCCEEECCCEEEEEECCCCCCCHHHHHHHHCCCCEEEECHHHH
TMIAKPLFRLLSFYHSWTGNWGIAIILLTITVKLLFFPLSAAGYRSMAKLRLVTPKLKRI
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
QDQYKGDRQRMHQAMMDFYKTEKINPMGGCFPILVQIPVFIALYWTILAAVELRYAPFAL
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
WITDLSSPDPKYLLPVLLGISMFIQTRLNPTPTDPIQAKIMQIMPVAFSAIFFFFPAGLV
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LYSLVNNILSIAQQWKITKMYGTAPSQDAPESPASKDAPELPVSNQVINDSENTEAPASG
HHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC
PADSPKKPVNIPRRMHKRTRKK
CCCCCCCCCCCHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA