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The map label for this gene is argD [H]

Identifier: 114332033

GI number: 114332033

Start: 2185180

End: 2186361

Strand: Reverse

Name: argD [H]

Synonym: Neut_2067

Alternate gene names: 114332033

Gene position: 2186361-2185180 (Counterclockwise)

Preceding gene: 114332034

Following gene: 114332032

Centisome position: 82.16

GC content: 49.75

Gene sequence:

>1182_bases
GTGTCTCATTTAATGAATACTTATGCACGGCTTCCCGTTACCTTTGTCAGGGGAGAAGGCGTTTGGCTGTGGGATGATCA
AGGTAATCGCTACCTTGATGCGCTATCAGGAATTGCGGTCTGCGGGGCTGGACATTGCCATCCGGTACTGACGAAAGCGT
TGTGTGAACAGGCTGCTACGTTAATACACACCTCTAATCTCTACCACATTCAGAATCAGGAGCGTTTGGCAGACAGATTG
ACCAGTCTGTCAGGCCTGGAGAAGGCTTTTTTCTGTAATTCCGGAGCAGAGTCGAATGAGGCAGCCATTAAACTGGCGCG
GCTTTATGGCCATAACCAGGGAATAGATCTGCCAACGATTATTGTTATGGAACGCTCATTTCATGGCCGGACCATGGCAA
CACTTACTGCCACGGGCAATCGCAAGACTCAAGCGGGTTTTGAGCCGCTACTCACGGGTTTCGTGCGTGTGCCCTATGAT
GATCTGGAAGCAGTCAACCAGGTTGCAGCGAACAACAAGGAAATTGTGGCGGTGCTACTGGAAACCTATCAGGGCGAAGG
TGGAGTTAATTTCCCACAAGCAAATTATCTGCAAGGGTTGCGCAAGATCTGCGACCAGAACGGTTGGTTGCTGATGCTTG
ATGAGGTACAGTGTGGCCTTGGACGGACGGGCAAGTGGTTTGCTTTTCAGCATAGTGATATCGTACCGGATGTCATGACA
CTGGCAAAAGGATTGGGATCCGGCCTGCCGATCGGCGCCTGCCTGGCAGGCGGGAAAGCAGCGGAAGTATTCAAGCCTGG
TAATCACGCATCTACTTTCGGTGGCAATCCACTTGCATGTAGAGCTGCCTTGACCACTCTTGACATCATTGAGCAGGAAG
GATTGATGGCTAATGCTGTGACTATCGGTAATTTCATGCGAGAGGAATTCAAGCAGAGATTACATGCCTGGCAAAACGTG
CTGAAAATTCGCGGGCAGGGGATGATGATCGGGGTTGAGCTGCCGATACCCTGTGGTGAACTTGTGCCTGAAGCATTGAA
ACGCCATTTGCTGATCAATGTAACATCTGAAAAAGTAGTACGATTACTGCCGGCATTGAATATGCAAAAGGCAGAGGCAG
AACAGGTGGTACATGAGGTATCCGCTCTTATTTCCTGGTTTCTTGAGAATCGAGAGAAATAA

Upstream 100 bases:

>100_bases
GTATAAATTTATTCAGAGGTTCTGAATGAGGGAACCTGTTCCCAGGAGTGGTGGCACCAGCCACCATGTTGTTTCAGAAC
AAAAATAGGGTGTATTTTCT

Downstream 100 bases:

>100_bases
TGATAAGGGTGTGAGCCGACGGTTGTCGCCAGAGTGCACTCGAAAGATTTTTTCTCGCTACATGGTTATCCCGCCTTTTT
TATTTTTCCGGATTCAAGTG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSHLMNTYARLPVTFVRGEGVWLWDDQGNRYLDALSGIAVCGAGHCHPVLTKALCEQAATLIHTSNLYHIQNQERLADRL
TSLSGLEKAFFCNSGAESNEAAIKLARLYGHNQGIDLPTIIVMERSFHGRTMATLTATGNRKTQAGFEPLLTGFVRVPYD
DLEAVNQVAANNKEIVAVLLETYQGEGGVNFPQANYLQGLRKICDQNGWLLMLDEVQCGLGRTGKWFAFQHSDIVPDVMT
LAKGLGSGLPIGACLAGGKAAEVFKPGNHASTFGGNPLACRAALTTLDIIEQEGLMANAVTIGNFMREEFKQRLHAWQNV
LKIRGQGMMIGVELPIPCGELVPEALKRHLLINVTSEKVVRLLPALNMQKAEAEQVVHEVSALISWFLENREK

Sequences:

>Translated_393_residues
MSHLMNTYARLPVTFVRGEGVWLWDDQGNRYLDALSGIAVCGAGHCHPVLTKALCEQAATLIHTSNLYHIQNQERLADRL
TSLSGLEKAFFCNSGAESNEAAIKLARLYGHNQGIDLPTIIVMERSFHGRTMATLTATGNRKTQAGFEPLLTGFVRVPYD
DLEAVNQVAANNKEIVAVLLETYQGEGGVNFPQANYLQGLRKICDQNGWLLMLDEVQCGLGRTGKWFAFQHSDIVPDVMT
LAKGLGSGLPIGACLAGGKAAEVFKPGNHASTFGGNPLACRAALTTLDIIEQEGLMANAVTIGNFMREEFKQRLHAWQNV
LKIRGQGMMIGVELPIPCGELVPEALKRHLLINVTSEKVVRLLPALNMQKAEAEQVVHEVSALISWFLENREK
>Mature_392_residues
SHLMNTYARLPVTFVRGEGVWLWDDQGNRYLDALSGIAVCGAGHCHPVLTKALCEQAATLIHTSNLYHIQNQERLADRLT
SLSGLEKAFFCNSGAESNEAAIKLARLYGHNQGIDLPTIIVMERSFHGRTMATLTATGNRKTQAGFEPLLTGFVRVPYDD
LEAVNQVAANNKEIVAVLLETYQGEGGVNFPQANYLQGLRKICDQNGWLLMLDEVQCGLGRTGKWFAFQHSDIVPDVMTL
AKGLGSGLPIGACLAGGKAAEVFKPGNHASTFGGNPLACRAALTTLDIIEQEGLMANAVTIGNFMREEFKQRLHAWQNVL
KIRGQGMMIGVELPIPCGELVPEALKRHLLINVTSEKVVRLLPALNMQKAEAEQVVHEVSALISWFLENREK

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=390, Percent_Identity=32.8205128205128, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI13994255, Length=446, Percent_Identity=29.8206278026906, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI284507298, Length=303, Percent_Identity=32.3432343234323, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=28.7735849056604, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI24119277, Length=414, Percent_Identity=27.7777777777778, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=27.5943396226415, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=28.8659793814433, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI188536080, Length=432, Percent_Identity=23.6111111111111, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI38679950, Length=432, Percent_Identity=23.6111111111111, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI38679946, Length=432, Percent_Identity=23.6111111111111, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI1789759, Length=385, Percent_Identity=38.961038961039, Blast_Score=258, Evalue=3e-70,
Organism=Escherichia coli, GI1788044, Length=391, Percent_Identity=37.5959079283887, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI145693181, Length=370, Percent_Identity=37.2972972972973, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1787560, Length=339, Percent_Identity=34.2182890855457, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=30.2955665024631, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1786991, Length=337, Percent_Identity=30.2670623145401, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786349, Length=299, Percent_Identity=28.7625418060201, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=388, Percent_Identity=33.2474226804124, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=30.8219178082192, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=272, Percent_Identity=32.7205882352941, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=361, Percent_Identity=26.5927977839335, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI71981843, Length=161, Percent_Identity=34.1614906832298, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17541228, Length=425, Percent_Identity=24.4705882352941, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71992985, Length=125, Percent_Identity=34.4, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=380, Percent_Identity=35.5263157894737, Blast_Score=234, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=32.5062034739454, Blast_Score=206, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6324386, Length=343, Percent_Identity=25.6559766763848, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321456, Length=374, Percent_Identity=24.0641711229947, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=32.6424870466321, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI28574759, Length=366, Percent_Identity=31.9672131147541, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161085790, Length=366, Percent_Identity=31.9672131147541, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=28.169014084507, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=24.824355971897, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=24.824355971897, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=24.824355971897, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43029; Mature: 42898

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLMNTYARLPVTFVRGEGVWLWDDQGNRYLDALSGIAVCGAGHCHPVLTKALCEQAAT
CCHHHHHHHHCCEEEEECCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LIHTSNLYHIQNQERLADRLTSLSGLEKAFFCNSGAESNEAAIKLARLYGHNQGIDLPTI
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCCCCCCCEE
IVMERSFHGRTMATLTATGNRKTQAGFEPLLTGFVRVPYDDLEAVNQVAANNKEIVAVLL
EEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
ETYQGEGGVNFPQANYLQGLRKICDQNGWLLMLDEVQCGLGRTGKWFAFQHSDIVPDVMT
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHH
LAKGLGSGLPIGACLAGGKAAEVFKPGNHASTFGGNPLACRAALTTLDIIEQEGLMANAV
HHHHCCCCCCHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEHHH
TIGNFMREEFKQRLHAWQNVLKIRGQGMMIGVELPIPCGELVPEALKRHLLINVTSEKVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHEEEEECHHHHH
RLLPALNMQKAEAEQVVHEVSALISWFLENREK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SHLMNTYARLPVTFVRGEGVWLWDDQGNRYLDALSGIAVCGAGHCHPVLTKALCEQAAT
CHHHHHHHHCCEEEEECCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LIHTSNLYHIQNQERLADRLTSLSGLEKAFFCNSGAESNEAAIKLARLYGHNQGIDLPTI
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCCCCCCCEE
IVMERSFHGRTMATLTATGNRKTQAGFEPLLTGFVRVPYDDLEAVNQVAANNKEIVAVLL
EEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
ETYQGEGGVNFPQANYLQGLRKICDQNGWLLMLDEVQCGLGRTGKWFAFQHSDIVPDVMT
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHH
LAKGLGSGLPIGACLAGGKAAEVFKPGNHASTFGGNPLACRAALTTLDIIEQEGLMANAV
HHHHCCCCCCHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEHHH
TIGNFMREEFKQRLHAWQNVLKIRGQGMMIGVELPIPCGELVPEALKRHLLINVTSEKVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHEEEEECHHHHH
RLLPALNMQKAEAEQVVHEVSALISWFLENREK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]