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The map label for this gene is trpS [H]

Identifier: 114332008

GI number: 114332008

Start: 2158356

End: 2159558

Strand: Direct

Name: trpS [H]

Synonym: Neut_2042

Alternate gene names: 114332008

Gene position: 2158356-2159558 (Clockwise)

Preceding gene: 114332007

Following gene: 114332009

Centisome position: 81.11

GC content: 49.04

Gene sequence:

>1203_bases
ATGTTTGTTGATCGCGTTCTCTCAGGCATGCGCCCTACAGGAAATCTACATCTGGGACATTACCATGGTGTATTGAAAAA
CTGGCTGGCCCTGCAACAGAAATATGAATGCCTCTTTTTTGTAGCTGATTGGCATGCATTGACGACTCATTACGACTCCC
CTGAAATCATTGAGCAGCATAGCTGGAACATGGTGGTCGATTGGCTGGCAGCAGGGGTAGATCCTGCACAAGCAACCTTG
TTCATTCAGTCGAAAGTCCCCGCACACGCCGAGTTATACTTATTATTATCAATGATTACCCCGCTTGGCTGGCTGGAACG
TGTCCCTACTTACAAGGATCAGCAGGAAAAACTTGTTGCGAAGGATCTCAGCACCTACGGTTTTCTCGGGTATCCCCTCC
TACAAAGCGCTGACATACTGGTTTACCGGGCCAATCTTGTTCCTGTAGGAGAAGACCAGGCGCCTCATTTGGAGTTTACG
CGTGAGGTATCCCGCCGGTTTAACCATATCTTTGGTAAAGAACCGGATTTCGAGAACAAAGTAACGCAAGCCATCAAAAG
AATGGGCTCTAAAAAAGGAAAGCTTTATGGTGAACTGCGTAACCGCTATCAGGAACAAGGTGACGAAAATGCGCTATCCG
AAGCCAGATTACTGCTGAAGGGACAACAAAATCTCAGCATGGATGATCGCGAGCGGCTATCCGGCTATCTGGAAGGAAGA
AGCAAGGTCATTTTGCCTGAGCCACAAACGCTATTGACCAAAGCGTCCAAAATGCCTGGTCTGGATGGCCAGAAGATGTC
CAAATCGTATGGCAACACAATTGGTTTGCGCGAAGATGTGGACAGTATTGCTCGAAAAATTCGCACCATGCCGACTGATC
CAGCACGCGTCCGCCGCAACGACCCTGGTAACCCGGAGAAATGCCCGGTATGGCAATTCCACCAGCTTTATTCATCAGAA
GATGCCCGGAAATGGGTATGGCAAGGCTGCACAACCGCAGGGATCGGGTGCCTGGAATGTAAACAACCGATCATTCAATC
AATACGGGAAGAACAGGCGCCTATTCTGGAACGTGCCAAAATGTATCAGGAAGACCCTGCTCAAGTAAAAAAAATTGTCG
CCGAAGGATGTGAAAAAGCCAATCAACTGGCAGAAGAAACCATGCGGGATGTCAGAGCGGCACTGGGGATCGGGTATCCG
TGA

Upstream 100 bases:

>100_bases
CATACTTTTTGGTCTTTATGTATAAATAGTATTTTTCTACGTTTCACCAGACACCCTTATATTTTTTCTTCGATTCCATG
CTATCCGGAGCTCTGTAAAA

Downstream 100 bases:

>100_bases
TGAATGACATATCCAGACAAACCCTTGCAGACACCGGGAATATATTGGATAACGCTGCGCTGAACGACCCGATTGCAAGA
GTACAAGGCATACCGCTACT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFVDRVLSGMRPTGNLHLGHYHGVLKNWLALQQKYECLFFVADWHALTTHYDSPEIIEQHSWNMVVDWLAAGVDPAQATL
FIQSKVPAHAELYLLLSMITPLGWLERVPTYKDQQEKLVAKDLSTYGFLGYPLLQSADILVYRANLVPVGEDQAPHLEFT
REVSRRFNHIFGKEPDFENKVTQAIKRMGSKKGKLYGELRNRYQEQGDENALSEARLLLKGQQNLSMDDRERLSGYLEGR
SKVILPEPQTLLTKASKMPGLDGQKMSKSYGNTIGLREDVDSIARKIRTMPTDPARVRRNDPGNPEKCPVWQFHQLYSSE
DARKWVWQGCTTAGIGCLECKQPIIQSIREEQAPILERAKMYQEDPAQVKKIVAEGCEKANQLAEETMRDVRAALGIGYP

Sequences:

>Translated_400_residues
MFVDRVLSGMRPTGNLHLGHYHGVLKNWLALQQKYECLFFVADWHALTTHYDSPEIIEQHSWNMVVDWLAAGVDPAQATL
FIQSKVPAHAELYLLLSMITPLGWLERVPTYKDQQEKLVAKDLSTYGFLGYPLLQSADILVYRANLVPVGEDQAPHLEFT
REVSRRFNHIFGKEPDFENKVTQAIKRMGSKKGKLYGELRNRYQEQGDENALSEARLLLKGQQNLSMDDRERLSGYLEGR
SKVILPEPQTLLTKASKMPGLDGQKMSKSYGNTIGLREDVDSIARKIRTMPTDPARVRRNDPGNPEKCPVWQFHQLYSSE
DARKWVWQGCTTAGIGCLECKQPIIQSIREEQAPILERAKMYQEDPAQVKKIVAEGCEKANQLAEETMRDVRAALGIGYP
>Mature_400_residues
MFVDRVLSGMRPTGNLHLGHYHGVLKNWLALQQKYECLFFVADWHALTTHYDSPEIIEQHSWNMVVDWLAAGVDPAQATL
FIQSKVPAHAELYLLLSMITPLGWLERVPTYKDQQEKLVAKDLSTYGFLGYPLLQSADILVYRANLVPVGEDQAPHLEFT
REVSRRFNHIFGKEPDFENKVTQAIKRMGSKKGKLYGELRNRYQEQGDENALSEARLLLKGQQNLSMDDRERLSGYLEGR
SKVILPEPQTLLTKASKMPGLDGQKMSKSYGNTIGLREDVDSIARKIRTMPTDPARVRRNDPGNPEKCPVWQFHQLYSSE
DARKWVWQGCTTAGIGCLECKQPIIQSIREEQAPILERAKMYQEDPAQVKKIVAEGCEKANQLAEETMRDVRAALGIGYP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=187, Percent_Identity=36.8983957219251, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI41352700, Length=170, Percent_Identity=39.4117647058824, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1789786, Length=168, Percent_Identity=39.8809523809524, Blast_Score=148, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71982800, Length=172, Percent_Identity=34.8837209302326, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71982793, Length=172, Percent_Identity=34.8837209302326, Blast_Score=110, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320474, Length=183, Percent_Identity=37.1584699453552, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24666151, Length=170, Percent_Identity=35.8823529411765, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 45514; Mature: 45514

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDRVLSGMRPTGNLHLGHYHGVLKNWLALQQKYECLFFVADWHALTTHYDSPEIIEQH
CCHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHCCCCCHHHHHHC
SWNMVVDWLAAGVDPAQATLFIQSKVPAHAELYLLLSMITPLGWLERVPTYKDQQEKLVA
CCHHHHHHHHCCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KDLSTYGFLGYPLLQSADILVYRANLVPVGEDQAPHLEFTREVSRRFNHIFGKEPDFENK
HHHHHHCCCCCHHHCCCCEEEEEECEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
VTQAIKRMGSKKGKLYGELRNRYQEQGDENALSEARLLLKGQQNLSMDDRERLSGYLEGR
HHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
SKVILPEPQTLLTKASKMPGLDGQKMSKSYGNTIGLREDVDSIARKIRTMPTDPARVRRN
CEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHCCC
DPGNPEKCPVWQFHQLYSSEDARKWVWQGCTTAGIGCLECKQPIIQSIREEQAPILERAK
CCCCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCHHHHHHH
MYQEDPAQVKKIVAEGCEKANQLAEETMRDVRAALGIGYP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFVDRVLSGMRPTGNLHLGHYHGVLKNWLALQQKYECLFFVADWHALTTHYDSPEIIEQH
CCHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHCCCCCHHHHHHC
SWNMVVDWLAAGVDPAQATLFIQSKVPAHAELYLLLSMITPLGWLERVPTYKDQQEKLVA
CCHHHHHHHHCCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KDLSTYGFLGYPLLQSADILVYRANLVPVGEDQAPHLEFTREVSRRFNHIFGKEPDFENK
HHHHHHCCCCCHHHCCCCEEEEEECEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
VTQAIKRMGSKKGKLYGELRNRYQEQGDENALSEARLLLKGQQNLSMDDRERLSGYLEGR
HHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
SKVILPEPQTLLTKASKMPGLDGQKMSKSYGNTIGLREDVDSIARKIRTMPTDPARVRRN
CEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHCCC
DPGNPEKCPVWQFHQLYSSEDARKWVWQGCTTAGIGCLECKQPIIQSIREEQAPILERAK
CCCCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCHHHHHHH
MYQEDPAQVKKIVAEGCEKANQLAEETMRDVRAALGIGYP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]