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The map label for this gene is btr [H]

Identifier: 114332002

GI number: 114332002

Start: 2151819

End: 2152547

Strand: Reverse

Name: btr [H]

Synonym: Neut_2036

Alternate gene names: 114332002

Gene position: 2152547-2151819 (Counterclockwise)

Preceding gene: 114332003

Following gene: 114332001

Centisome position: 80.89

GC content: 46.78

Gene sequence:

>729_bases
ATGCCTGGTAATTCCACTGTCCTGCAGCAAAAATCCGACTGTATGACTTGCAGTTTTCGAGAGTTGTGTCTGCCGGTGGG
GTTGACTGATGAGGAAATAGAGTATCTTGGTAATCTGATCAATTATAAATTCAAGGTGCGGAGAGGCGAGTATTTGTCGC
ATGCCGGATCTGATTTCAAGTCACTCTACGCAGTAAAAAACGGCTCCTTTAAAACTTGTGTGCTGAAGGTGGATGGGCGC
CAGCAGGTGACTGGCTTTTATATGACAGGCGAGCTGCTGGGACTGGATGCGATCAGTCCGGAGAAGCATACTTGTGACAC
GGTTGCGCTGGTTGATAGTGAAGTCTGTGAAGTGCCTTTCAAAAAACTTGAGGAAATCGGGCAAAATATTCCTTCATTGA
TGAGTCAGCTTCACAAGATTATGAGCCGTGAAATTGTGCAGGACAGAGGGGTTATGATGCTACTGGGCAGCATGCGGGCA
GAAGAACGGCTGGCTGCTTTTTTGCTTAACCTATCTACCCGCCTGGCCAGACGGGGGTATTCGCCAACGGATTTTATTTT
GAGAGCAACAAGGGAAGATATTGGCAGTTATCTGGGGCTCAAGCTGGAAACAGTCAGTCGATCATTCTCCAAGCTGCAGG
AGGAAGGGCTTATCACGGTTAATATCAAACATATCACATTACATGACGTTGATAAGTTGAACCTCAGAATTGGTAATTCA
GCGGACTGA

Upstream 100 bases:

>100_bases
CTGGCGGAGTATGTGCTGATAAATAGTGTGACTAGATAAATCAGTGCTGGTTTTTATTCCTCTCTAAATTAAGGTGGGAG
TCGTTTTGTATAACTGCGCA

Downstream 100 bases:

>100_bases
TTTCGGTTTCATCCGATTTGAAAAATGAGTTTTCTTGAGCACAGGATCTGCCATGTTATAATGGCGTGCGGTGCCAGAGG
TGATTTTCTGCGCCGAGGAA

Product: transcriptional regulator, Crp/Fnr family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MPGNSTVLQQKSDCMTCSFRELCLPVGLTDEEIEYLGNLINYKFKVRRGEYLSHAGSDFKSLYAVKNGSFKTCVLKVDGR
QQVTGFYMTGELLGLDAISPEKHTCDTVALVDSEVCEVPFKKLEEIGQNIPSLMSQLHKIMSREIVQDRGVMMLLGSMRA
EERLAAFLLNLSTRLARRGYSPTDFILRATREDIGSYLGLKLETVSRSFSKLQEEGLITVNIKHITLHDVDKLNLRIGNS
AD

Sequences:

>Translated_242_residues
MPGNSTVLQQKSDCMTCSFRELCLPVGLTDEEIEYLGNLINYKFKVRRGEYLSHAGSDFKSLYAVKNGSFKTCVLKVDGR
QQVTGFYMTGELLGLDAISPEKHTCDTVALVDSEVCEVPFKKLEEIGQNIPSLMSQLHKIMSREIVQDRGVMMLLGSMRA
EERLAAFLLNLSTRLARRGYSPTDFILRATREDIGSYLGLKLETVSRSFSKLQEEGLITVNIKHITLHDVDKLNLRIGNS
AD
>Mature_241_residues
PGNSTVLQQKSDCMTCSFRELCLPVGLTDEEIEYLGNLINYKFKVRRGEYLSHAGSDFKSLYAVKNGSFKTCVLKVDGRQ
QVTGFYMTGELLGLDAISPEKHTCDTVALVDSEVCEVPFKKLEEIGQNIPSLMSQLHKIMSREIVQDRGVMMLLGSMRAE
ERLAAFLLNLSTRLARRGYSPTDFILRATREDIGSYLGLKLETVSRSFSKLQEEGLITVNIKHITLHDVDKLNLRIGNSA
D

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=227, Percent_Identity=41.8502202643172, Blast_Score=198, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27133; Mature: 27002

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGNSTVLQQKSDCMTCSFRELCLPVGLTDEEIEYLGNLINYKFKVRRGEYLSHAGSDFK
CCCCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCEEEEEECCHHHHHCCCCHH
SLYAVKNGSFKTCVLKVDGRQQVTGFYMTGELLGLDAISPEKHTCDTVALVDSEVCEVPF
HHHHCCCCCEEEEEEEECCCCEEEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHCCH
KKLEEIGQNIPSLMSQLHKIMSREIVQDRGVMMLLGSMRAEERLAAFLLNLSTRLARRGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPTDFILRATREDIGSYLGLKLETVSRSFSKLQEEGLITVNIKHITLHDVDKLNLRIGNS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEEEEEEECCCEEEEEECCC
AD
CC
>Mature Secondary Structure 
PGNSTVLQQKSDCMTCSFRELCLPVGLTDEEIEYLGNLINYKFKVRRGEYLSHAGSDFK
CCCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCEEEEEECCHHHHHCCCCHH
SLYAVKNGSFKTCVLKVDGRQQVTGFYMTGELLGLDAISPEKHTCDTVALVDSEVCEVPF
HHHHCCCCCEEEEEEEECCCCEEEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHCCH
KKLEEIGQNIPSLMSQLHKIMSREIVQDRGVMMLLGSMRAEERLAAFLLNLSTRLARRGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPTDFILRATREDIGSYLGLKLETVSRSFSKLQEEGLITVNIKHITLHDVDKLNLRIGNS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEEEEEEECCCEEEEEECCC
AD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]