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The map label for this gene is atpA2

Identifier: 114331986

GI number: 114331986

Start: 2133234

End: 2134784

Strand: Direct

Name: atpA2

Synonym: Neut_2020

Alternate gene names: 114331986

Gene position: 2133234-2134784 (Clockwise)

Preceding gene: 114331985

Following gene: 114331987

Centisome position: 80.16

GC content: 51.32

Gene sequence:

>1551_bases
GTGAGTGTACTTGACGATGTCACTGAGCAGCAGTTTGAGCAAAACTTTAACGCTTGGTTAGACAGTCTCAGCACAGGTGC
CACACCCACGCCGGTACTCACCGAAACCGGCACAGTGACCGAGGTGGCGGATGGTGTGGCCATCGTCTCAGGTCTGGCGC
GCGCCTTAGCTGATGAGTTGCTGGTATTTGCCAGCGGTGTGCACGGTATTGTGCTCGACTTGGAACCGGGTCGCTTAGGG
ATTATTTTATTGGGCCCGTCTGAACAGATCCACTTAGGCGAGACGGTGTATCGCACTCGTAAAGTAGTCAGTGTGCCAGT
GGGCTCGGCGTTACTTGGGCGCGTAATCGATGCTATGGGCCGTCCACGTGATACCTTAGGACCGATTGATGCGATAGCTG
AGCATCCCATTGAAGCGGAAGCGCCGAGTATTCTAAATCGCACCCAGATTTTCAGACCCTTAGCCACGGGATTAAAGGCT
ATTGATGCGGCGATCCCAGTGGGTTTAGGCCAGCGTGAATTGATTATTGGCGATCGCCAGACTGGTAAAACTTCTATCGC
TATCGACACTATGCTGAATCAGGCACGTTCGGATGTGCTTTGTATTTACTGCGCAGTGGGGCAACGCGGTGATGCTGTCG
CACGGGTGATTCGTGCGCTCAAAGATGGCGAAATGCTGCAGCGCTGCATTGTGATGAGTGCCGGTGATGAAGAAGCTCCA
GGGCTGTCCTATATTGCGCCCTATGCGGCTATGACTATGGCGGAATATTTCTCGGCGCAGGGCCAAGATGTATTGGTGAT
CTTTGATGATATGACTCATCATGCGCGCTCTTATCGCGAATTATCGTTATTGCTGCGTCGACCACCAGGACGTGAAGCCT
TTCCTGGGGATATTTTCTATGTGCATGCGCGTCTTTTAGAGCGCGCTGGACAATTTGGCGCCGACATCGGTGGCGGATCG
ATTACCACTTTGCCCGTGGTAGAAACGCAGGCCGGAAACCTCTCGGCTTATATTCCTACTAACCTCATTTCGATTACTGA
TGGGCAGATTTATTTATCGCCGCAGTTAGTACGTAAAAACCAATTCCCCGCAGTAGATTTAGGACTGTCCGTGTCACGGG
TTGGTAGTAAAGCGCAGAACCGTACCTTGCGTGGAGTGTCAGGCAACTTGCGGGTGACCCTCTCACAATTTGAAGAGTTG
GAAGATTTTGCCCGCTTTGGTACACGGCTCGATGATGTTACCCGTGCACGTTTGGCACGTGGTTCTGCGGTGCGTACCGC
CTTACGTCAAGCTGAGCGTGACCCGATGTCTGCCCTTGAGCAGCTGGCGGTGTTGATCGCAGCGATGGAAGGCTTATTTG
ATCAGTTTAATGAGCAAAAAATTAATGATGCTATGCGTTTAGTGCGTGATGCCGCCCAACAACAGCTGGCTGTGATTGAA
CAACGTATTATTGATAACCAAACCCTACAGGATGACGATCACACACTGATTGTTAATTGCGCGCAAAAAGCTTTAAGCAT
ATTCGATCAGCCAGCAACGAATACAAAGTAG

Upstream 100 bases:

>100_bases
GGACAGCTATATGGATGAGTTAGCCGAACTGTTAACCCAGCATACTTCTAGCGTTGCTGCTGTGCACTTAACCGCTGATG
GCCGCTAAAAAGGAATTGAA

Downstream 100 bases:

>100_bases
TGAGATGGCACAAACTCTAGAGCATCTATCGCGAAAAAATAATACCCTAACCAGCATCAGGGGTATTGTGCATACGATGA
AAACCCTATCAGCAATTAAT

Product: ATP synthase F1, alpha subunit

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MSVLDDVTEQQFEQNFNAWLDSLSTGATPTPVLTETGTVTEVADGVAIVSGLARALADELLVFASGVHGIVLDLEPGRLG
IILLGPSEQIHLGETVYRTRKVVSVPVGSALLGRVIDAMGRPRDTLGPIDAIAEHPIEAEAPSILNRTQIFRPLATGLKA
IDAAIPVGLGQRELIIGDRQTGKTSIAIDTMLNQARSDVLCIYCAVGQRGDAVARVIRALKDGEMLQRCIVMSAGDEEAP
GLSYIAPYAAMTMAEYFSAQGQDVLVIFDDMTHHARSYRELSLLLRRPPGREAFPGDIFYVHARLLERAGQFGADIGGGS
ITTLPVVETQAGNLSAYIPTNLISITDGQIYLSPQLVRKNQFPAVDLGLSVSRVGSKAQNRTLRGVSGNLRVTLSQFEEL
EDFARFGTRLDDVTRARLARGSAVRTALRQAERDPMSALEQLAVLIAAMEGLFDQFNEQKINDAMRLVRDAAQQQLAVIE
QRIIDNQTLQDDDHTLIVNCAQKALSIFDQPATNTK

Sequences:

>Translated_516_residues
MSVLDDVTEQQFEQNFNAWLDSLSTGATPTPVLTETGTVTEVADGVAIVSGLARALADELLVFASGVHGIVLDLEPGRLG
IILLGPSEQIHLGETVYRTRKVVSVPVGSALLGRVIDAMGRPRDTLGPIDAIAEHPIEAEAPSILNRTQIFRPLATGLKA
IDAAIPVGLGQRELIIGDRQTGKTSIAIDTMLNQARSDVLCIYCAVGQRGDAVARVIRALKDGEMLQRCIVMSAGDEEAP
GLSYIAPYAAMTMAEYFSAQGQDVLVIFDDMTHHARSYRELSLLLRRPPGREAFPGDIFYVHARLLERAGQFGADIGGGS
ITTLPVVETQAGNLSAYIPTNLISITDGQIYLSPQLVRKNQFPAVDLGLSVSRVGSKAQNRTLRGVSGNLRVTLSQFEEL
EDFARFGTRLDDVTRARLARGSAVRTALRQAERDPMSALEQLAVLIAAMEGLFDQFNEQKINDAMRLVRDAAQQQLAVIE
QRIIDNQTLQDDDHTLIVNCAQKALSIFDQPATNTK
>Mature_515_residues
SVLDDVTEQQFEQNFNAWLDSLSTGATPTPVLTETGTVTEVADGVAIVSGLARALADELLVFASGVHGIVLDLEPGRLGI
ILLGPSEQIHLGETVYRTRKVVSVPVGSALLGRVIDAMGRPRDTLGPIDAIAEHPIEAEAPSILNRTQIFRPLATGLKAI
DAAIPVGLGQRELIIGDRQTGKTSIAIDTMLNQARSDVLCIYCAVGQRGDAVARVIRALKDGEMLQRCIVMSAGDEEAPG
LSYIAPYAAMTMAEYFSAQGQDVLVIFDDMTHHARSYRELSLLLRRPPGREAFPGDIFYVHARLLERAGQFGADIGGGSI
TTLPVVETQAGNLSAYIPTNLISITDGQIYLSPQLVRKNQFPAVDLGLSVSRVGSKAQNRTLRGVSGNLRVTLSQFEELE
DFARFGTRLDDVTRARLARGSAVRTALRQAERDPMSALEQLAVLIAAMEGLFDQFNEQKINDAMRLVRDAAQQQLAVIEQ
RIIDNQTLQDDDHTLIVNCAQKALSIFDQPATNTK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=454, Percent_Identity=46.9162995594714, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI4757810, Length=454, Percent_Identity=46.9162995594714, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI19913426, Length=305, Percent_Identity=28.8524590163934, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI19913428, Length=299, Percent_Identity=28.0936454849498, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI32189394, Length=312, Percent_Identity=27.8846153846154, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI19913424, Length=237, Percent_Identity=28.2700421940928, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1790172, Length=436, Percent_Identity=45.1834862385321, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1788251, Length=351, Percent_Identity=30.1994301994302, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790170, Length=328, Percent_Identity=27.4390243902439, Blast_Score=99, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=437, Percent_Identity=46.9107551487414, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI71988080, Length=437, Percent_Identity=46.9107551487414, Blast_Score=419, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI71988074, Length=437, Percent_Identity=43.0205949656751, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17510931, Length=293, Percent_Identity=26.962457337884, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17570191, Length=297, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25144756, Length=301, Percent_Identity=26.2458471760797, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565854, Length=235, Percent_Identity=25.9574468085106, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=439, Percent_Identity=48.0637813211845, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322581, Length=405, Percent_Identity=26.1728395061728, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319603, Length=300, Percent_Identity=27, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320016, Length=129, Percent_Identity=30.2325581395349, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24658560, Length=464, Percent_Identity=44.8275862068966, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI281361666, Length=299, Percent_Identity=28.4280936454849, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24646341, Length=299, Percent_Identity=28.4280936454849, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17136796, Length=299, Percent_Identity=28.4280936454849, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24638766, Length=303, Percent_Identity=28.0528052805281, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28574560, Length=333, Percent_Identity=26.4264264264264, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129479, Length=253, Percent_Identity=26.8774703557312, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583988, Length=237, Percent_Identity=27.4261603375527, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583986, Length=237, Percent_Identity=27.4261603375527, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583984, Length=237, Percent_Identity=27.4261603375527, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583992, Length=237, Percent_Identity=27.4261603375527, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA2_NITEC (Q0AEI9)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748208.1
- ProteinModelPortal:   Q0AEI9
- SMR:   Q0AEI9
- STRING:   Q0AEI9
- GeneID:   4273267
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2020
- NMPDR:   fig|335283.3.peg.2481
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   MERFVES
- ProtClustDB:   CLSK958227
- BioCyc:   NEUT335283:NEUT_2020-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55893; Mature: 55761

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLDDVTEQQFEQNFNAWLDSLSTGATPTPVLTETGTVTEVADGVAIVSGLARALADEL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
LVFASGVHGIVLDLEPGRLGIILLGPSEQIHLGETVYRTRKVVSVPVGSALLGRVIDAMG
HHHHCCCCEEEEEECCCCEEEEEECCCCCEECCHHHHHHHHHEECCCCHHHHHHHHHHHC
RPRDTLGPIDAIAEHPIEAEAPSILNRTQIFRPLATGLKAIDAAIPVGLGQRELIIGDRQ
CCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
TGKTSIAIDTMLNQARSDVLCIYCAVGQRGDAVARVIRALKDGEMLQRCIVMSAGDEEAP
CCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
GLSYIAPYAAMTMAEYFSAQGQDVLVIFDDMTHHARSYRELSLLLRRPPGREAFPGDIFY
CCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
VHARLLERAGQFGADIGGGSITTLPVVETQAGNLSAYIPTNLISITDGQIYLSPQLVRKN
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEECHHHHHCC
QFPAVDLGLSVSRVGSKAQNRTLRGVSGNLRVTLSQFEELEDFARFGTRLDDVTRARLAR
CCCEEECCCCHHHHCCHHHCCEECCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHC
GSAVRTALRQAERDPMSALEQLAVLIAAMEGLFDQFNEQKINDAMRLVRDAAQQQLAVIE
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIIDNQTLQDDDHTLIVNCAQKALSIFDQPATNTK
HHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SVLDDVTEQQFEQNFNAWLDSLSTGATPTPVLTETGTVTEVADGVAIVSGLARALADEL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
LVFASGVHGIVLDLEPGRLGIILLGPSEQIHLGETVYRTRKVVSVPVGSALLGRVIDAMG
HHHHCCCCEEEEEECCCCEEEEEECCCCCEECCHHHHHHHHHEECCCCHHHHHHHHHHHC
RPRDTLGPIDAIAEHPIEAEAPSILNRTQIFRPLATGLKAIDAAIPVGLGQRELIIGDRQ
CCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
TGKTSIAIDTMLNQARSDVLCIYCAVGQRGDAVARVIRALKDGEMLQRCIVMSAGDEEAP
CCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
GLSYIAPYAAMTMAEYFSAQGQDVLVIFDDMTHHARSYRELSLLLRRPPGREAFPGDIFY
CCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
VHARLLERAGQFGADIGGGSITTLPVVETQAGNLSAYIPTNLISITDGQIYLSPQLVRKN
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEECHHHHHCC
QFPAVDLGLSVSRVGSKAQNRTLRGVSGNLRVTLSQFEELEDFARFGTRLDDVTRARLAR
CCCEEECCCCHHHHCCHHHCCEECCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHC
GSAVRTALRQAERDPMSALEQLAVLIAAMEGLFDQFNEQKINDAMRLVRDAAQQQLAVIE
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIIDNQTLQDDDHTLIVNCAQKALSIFDQPATNTK
HHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA