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The map label for this gene is cobO [H]

Identifier: 114331893

GI number: 114331893

Start: 2029826

End: 2030434

Strand: Direct

Name: cobO [H]

Synonym: Neut_1918

Alternate gene names: 114331893

Gene position: 2029826-2030434 (Clockwise)

Preceding gene: 114331892

Following gene: 114331894

Centisome position: 76.28

GC content: 54.52

Gene sequence:

>609_bases
ATGAACGCTGAAGCAGATCGGGCGCAGCGCCACCGTGCCCGAATGCAACGCCAAAAGACAGTTGTCGATGCCGCGATTGC
CCGTGCTGATAAAAGTAAAGGCTTGCTGCTGGTATTGACCGGCAACGGCAAGGGTAAATCAAGCTCCGCTTTCGGCATGG
CTGCCCGCGCACTGGGTCATAGTATGCGCGTTGGCGTCGCGCAGTTCATCAAGGGGCGCTCCGACACCGGCGAAGAAGCT
TTCTTCCAACAGCAGAAAAATATCATCTGGCATGTGCTGGGGGAAGGCTTTACCTGGGATACACAAGATCTTGAACGCGA
CAAGGAAACTGCCAGACGTGGATGGGCAGTTGTACAAACCATGCTGCATGATCCCTCCATTGACCTGCTGATACTGGATG
AGCTCACCTACCCGCTCAAGTTTGGCTGGCTGGACATCAATACCGTATTAGCTGATCTGCAGAACCGCCCGGCGATGCAG
CATGTTGTCATTACCGGCCGTGCCGCACCGGATGCTTTATGCCAGACAGCCGATACCGTCACCGAAATGCGTGATATCAA
ACACGCCTTCCAGTCTGGGATCCAGGCACAAATAGGGATTGATTACTGA

Upstream 100 bases:

>100_bases
TACTGTTTTACGTCAGCATGGCAGCAGCAATACACATCCCTCTTGCGTTGATCCATCAATCGCGTTACCCCCGGAATAAT
GCAATCAGCCAATACCAATA

Downstream 100 bases:

>100_bases
CAACGCCACTCCGGAAGCTTGTCAGTAGAAGAAACCTTACAACTGCCCAGGATCCATCAGTAAAACGCTGATTTATCCGC
CACTAAGAGGCCTGCAAGGC

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MNAEADRAQRHRARMQRQKTVVDAAIARADKSKGLLLVLTGNGKGKSSSAFGMAARALGHSMRVGVAQFIKGRSDTGEEA
FFQQQKNIIWHVLGEGFTWDTQDLERDKETARRGWAVVQTMLHDPSIDLLILDELTYPLKFGWLDINTVLADLQNRPAMQ
HVVITGRAAPDALCQTADTVTEMRDIKHAFQSGIQAQIGIDY

Sequences:

>Translated_202_residues
MNAEADRAQRHRARMQRQKTVVDAAIARADKSKGLLLVLTGNGKGKSSSAFGMAARALGHSMRVGVAQFIKGRSDTGEEA
FFQQQKNIIWHVLGEGFTWDTQDLERDKETARRGWAVVQTMLHDPSIDLLILDELTYPLKFGWLDINTVLADLQNRPAMQ
HVVITGRAAPDALCQTADTVTEMRDIKHAFQSGIQAQIGIDY
>Mature_202_residues
MNAEADRAQRHRARMQRQKTVVDAAIARADKSKGLLLVLTGNGKGKSSSAFGMAARALGHSMRVGVAQFIKGRSDTGEEA
FFQQQKNIIWHVLGEGFTWDTQDLERDKETARRGWAVVQTMLHDPSIDLLILDELTYPLKFGWLDINTVLADLQNRPAMQ
HVVITGRAAPDALCQTADTVTEMRDIKHAFQSGIQAQIGIDY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=194, Percent_Identity=45.8762886597938, Blast_Score=184, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22445; Mature: 22445

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEADRAQRHRARMQRQKTVVDAAIARADKSKGLLLVLTGNGKGKSSSAFGMAARALGH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
SMRVGVAQFIKGRSDTGEEAFFQQQKNIIWHVLGEGFTWDTQDLERDKETARRGWAVVQT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
MLHDPSIDLLILDELTYPLKFGWLDINTVLADLQNRPAMQHVVITGRAAPDALCQTADTV
HHCCCCCCEEEECCCCCCCEECCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
TEMRDIKHAFQSGIQAQIGIDY
HHHHHHHHHHHCCCEEEECCCC
>Mature Secondary Structure
MNAEADRAQRHRARMQRQKTVVDAAIARADKSKGLLLVLTGNGKGKSSSAFGMAARALGH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
SMRVGVAQFIKGRSDTGEEAFFQQQKNIIWHVLGEGFTWDTQDLERDKETARRGWAVVQT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
MLHDPSIDLLILDELTYPLKFGWLDINTVLADLQNRPAMQHVVITGRAAPDALCQTADTV
HHCCCCCCEEEECCCCCCCEECCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
TEMRDIKHAFQSGIQAQIGIDY
HHHHHHHHHHHCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]