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The map label for this gene is aroQ

Identifier: 114331876

GI number: 114331876

Start: 2016693

End: 2017130

Strand: Reverse

Name: aroQ

Synonym: Neut_1901

Alternate gene names: 114331876

Gene position: 2017130-2016693 (Counterclockwise)

Preceding gene: 114331878

Following gene: 114331875

Centisome position: 75.8

GC content: 46.35

Gene sequence:

>438_bases
ATGGTTGCGAAAATCCTGGTTGTTCACGGTCCTAATTTGAATCTTTTAGGTAGAAGAGAGCCGTCCATTTATGGGCATAC
AACATTGGAAGATATTAACAGGAATCTGGTCGCGAAGGCGCAGGCAGCTTCTGTGGTGTTGGATACCTTTCAAAGCAATG
CCGAGCATGAATTGATCGATCGTGTACAAGAAGCCATGAATGACGGCACTGGCTTTATTATCATCAATCCCGCCGCTTTA
ACACATACTAGTATAGCCCTGCGTGATGCCCTGGCTGCCACAAATCTGCCTTTTGTAGAAATTCATCTTTCCAATATCTA
TGCTCGCGAACATTTTCGCCACACATCCTATTTCTCGGATATTGCTGTTGGGGTTATCAGTGGATTGGGTGCTGCGGGGT
ATGAGCTGGCTCTGCAATTTGCTTTGGCCAGGCAGTAG

Upstream 100 bases:

>100_bases
TAAATATTCTTTAACTTCGGCGAAAACACATAAAAAACTGTACAATAATACGATAACACGCCATAATTAATTCGTGGAAG
CGGATGGTTAATATAGTGTA

Downstream 100 bases:

>100_bases
TGTAAAACGGGGCATGACTCCAATATATTTGTCCTAAATCAGTTAAATTATTTTTTTACCCGGTGATCAATACAAATACA
AATGACAAAGCAGACTTGAT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MVAKILVVHGPNLNLLGRREPSIYGHTTLEDINRNLVAKAQAASVVLDTFQSNAEHELIDRVQEAMNDGTGFIIINPAAL
THTSIALRDALAATNLPFVEIHLSNIYAREHFRHTSYFSDIAVGVISGLGAAGYELALQFALARQ

Sequences:

>Translated_145_residues
MVAKILVVHGPNLNLLGRREPSIYGHTTLEDINRNLVAKAQAASVVLDTFQSNAEHELIDRVQEAMNDGTGFIIINPAAL
THTSIALRDALAATNLPFVEIHLSNIYAREHFRHTSYFSDIAVGVISGLGAAGYELALQFALARQ
>Mature_145_residues
MVAKILVVHGPNLNLLGRREPSIYGHTTLEDINRNLVAKAQAASVVLDTFQSNAEHELIDRVQEAMNDGTGFIIINPAAL
THTSIALRDALAATNLPFVEIHLSNIYAREHFRHTSYFSDIAVGVISGLGAAGYELALQFALARQ

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_NITEC (Q0AEU9)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748098.1
- ProteinModelPortal:   Q0AEU9
- SMR:   Q0AEU9
- STRING:   Q0AEU9
- GeneID:   4274147
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1901
- NMPDR:   fig|335283.3.peg.1026
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   NEUT335283:NEUT_1901-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15775; Mature: 15775

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 102-102 BINDING 76-76 BINDING 82-82 BINDING 89-89 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKILVVHGPNLNLLGRREPSIYGHTTLEDINRNLVAKAQAASVVLDTFQSNAEHELID
CCEEEEEEECCCCCEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHH
RVQEAMNDGTGFIIINPAALTHTSIALRDALAATNLPFVEIHLSNIYAREHFRHTSYFSD
HHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHH
IAVGVISGLGAAGYELALQFALARQ
HHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVAKILVVHGPNLNLLGRREPSIYGHTTLEDINRNLVAKAQAASVVLDTFQSNAEHELID
CCEEEEEEECCCCCEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHH
RVQEAMNDGTGFIIINPAALTHTSIALRDALAATNLPFVEIHLSNIYAREHFRHTSYFSD
HHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHH
IAVGVISGLGAAGYELALQFALARQ
HHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA