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The map label for this gene is lnt [H]

Identifier: 114331845

GI number: 114331845

Start: 1982608

End: 1984101

Strand: Reverse

Name: lnt [H]

Synonym: Neut_1870

Alternate gene names: 114331845

Gene position: 1984101-1982608 (Counterclockwise)

Preceding gene: 114331846

Following gene: 114331844

Centisome position: 74.56

GC content: 55.02

Gene sequence:

>1494_bases
TTGAACGGTTATTACAGGCTGATTGCTGCCTTCCTGCTGGGTGGAGTGACAGTAACCGGCTTTGCCCCTTTTTATTTTTA
TCCGGCACCCGTTGCCACACTGGTGTTGCTTGCCTTGCTCTGGCGCACAAGCAGAACACCCATGCAAGCAGCATCAACCG
GGTTTGCATTTGGCATGGGTCTGTTTGGCATAGGAGTGACCTGGCTTTACGTCAGTCTGCATGATTTTGGTCATATGGCG
CCTGCGCTGGCAGTGCGGGCGCTGATCGTGTTATGTGCCTATCTTTCATTATTTCCTGCACTGGCTGGCGGGATCGCAGC
GCTGCGGTATTTTCGTGCCTCCTGGGCGTGGCCGGGAGTGGTGGCAGCACTCTGGGCATTGATGGAATGGCTGCGCGGTA
CTCTGTTCACCGGTTTTCCGTGGCTGGCAGTCGGTTATTCACAAGCGCCGGATAGTCCTCTGGCAGGCTTTGCGCCGATT
GTGGGCGTGTATGGCATATCGCTGTTGCTGATGCTGAGCGCCGCCTGGCTGGCCTGCTGGTTGGAAAACAGACAAAACCG
TCGTTTCTGGCTATGGCTGGGCAGTGTCTGGATCATTGGTTTCAGCTTGCAACAAATACATTGGACTCAACCGGAAGGCG
AGCCGGTGACCGTCAGCTTGTTGCAAGGCAACATTCCACAGAACATGAAATGGGAGCCGGAGCATCTAGCCGCCACCATG
CGGACGTATGTCCGGCTGGTGCAGGAAAGTCCGAGCAGATTGATTGTAACCCCGGAAATTTCGTTTCCTCTGTATTACGA
ACAGGCACCACGGGATTATCTGGGATTGCTGACCGAACACGCTCGCTCCCGTCAGGGCGATGTACTGATCGGCCTGGTGG
AACGTTCCCCGGCGGGGGACAGTTATTACAACACCATGTTCAGTTTCGGTGCTTCACCCGAGCAAAGTTATCGTAAATAT
CATTTGGTTCCGTTTGGTGAATACATTCCGCTGAAGCCGATATTTGGTTGGGTGATCGATGTGCTGCATATTCCGTTATC
GGATTTCTCACGCGGCGGGCTGGATCAGCAGCCGCTGAATCTGGCCGGGCAGCGCGTGGCTGTCAATATTTGCTACGAAG
ATGTGTTTGGCGAAGAAATCATCATGCAGCTGCCGCAGGCTAGTCTACTGGTTAATGTCAGCAATGACGCCTGGTTCGGC
CATTCCATCGGCCCGCATCAGCATTTGCAGATTTCGCAGATGCGTGCGCTGGAAACCGGCCGTTACATGCTGCGCGCCAC
CAATACCGGAGTCACTGCCATCATCAATGAGCGGGGCAAGGTACTGGAGCAGCTGGAGATGTTCACCACTGCCGGTTTGC
ACAGCGCCGCGCAGGGCTTTGGCGGGGCCACGCCCTATGTGCGCCTGGGTAACAGTCTCTTATTCGGGTTAATTGGTTTG
CTGCTACTTACCGGTTGCTTGGCGGCATTTTCCGGCAAGCGCAAAACTCTGTAA

Upstream 100 bases:

>100_bases
TTATACATCCCTTTCAAATTCATCTCTGAACTGGGAAAACAGTAAAAATCAAGCCTTGTTTTCCTTTTTCTTCTCGTGAT
TTAGCCGGAGTGTCAATAAA

Downstream 100 bases:

>100_bases
AATGCCCCGATTCATTATCAAGCTACTATGACATGCCTACCCCCACTTTCCAGGAAATTATTCTTACCCTTCAACACTAC
TGGGGGCAGCAGGGATGCGC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNGYYRLIAAFLLGGVTVTGFAPFYFYPAPVATLVLLALLWRTSRTPMQAASTGFAFGMGLFGIGVTWLYVSLHDFGHMA
PALAVRALIVLCAYLSLFPALAGGIAALRYFRASWAWPGVVAALWALMEWLRGTLFTGFPWLAVGYSQAPDSPLAGFAPI
VGVYGISLLLMLSAAWLACWLENRQNRRFWLWLGSVWIIGFSLQQIHWTQPEGEPVTVSLLQGNIPQNMKWEPEHLAATM
RTYVRLVQESPSRLIVTPEISFPLYYEQAPRDYLGLLTEHARSRQGDVLIGLVERSPAGDSYYNTMFSFGASPEQSYRKY
HLVPFGEYIPLKPIFGWVIDVLHIPLSDFSRGGLDQQPLNLAGQRVAVNICYEDVFGEEIIMQLPQASLLVNVSNDAWFG
HSIGPHQHLQISQMRALETGRYMLRATNTGVTAIINERGKVLEQLEMFTTAGLHSAAQGFGGATPYVRLGNSLLFGLIGL
LLLTGCLAAFSGKRKTL

Sequences:

>Translated_497_residues
MNGYYRLIAAFLLGGVTVTGFAPFYFYPAPVATLVLLALLWRTSRTPMQAASTGFAFGMGLFGIGVTWLYVSLHDFGHMA
PALAVRALIVLCAYLSLFPALAGGIAALRYFRASWAWPGVVAALWALMEWLRGTLFTGFPWLAVGYSQAPDSPLAGFAPI
VGVYGISLLLMLSAAWLACWLENRQNRRFWLWLGSVWIIGFSLQQIHWTQPEGEPVTVSLLQGNIPQNMKWEPEHLAATM
RTYVRLVQESPSRLIVTPEISFPLYYEQAPRDYLGLLTEHARSRQGDVLIGLVERSPAGDSYYNTMFSFGASPEQSYRKY
HLVPFGEYIPLKPIFGWVIDVLHIPLSDFSRGGLDQQPLNLAGQRVAVNICYEDVFGEEIIMQLPQASLLVNVSNDAWFG
HSIGPHQHLQISQMRALETGRYMLRATNTGVTAIINERGKVLEQLEMFTTAGLHSAAQGFGGATPYVRLGNSLLFGLIGL
LLLTGCLAAFSGKRKTL
>Mature_497_residues
MNGYYRLIAAFLLGGVTVTGFAPFYFYPAPVATLVLLALLWRTSRTPMQAASTGFAFGMGLFGIGVTWLYVSLHDFGHMA
PALAVRALIVLCAYLSLFPALAGGIAALRYFRASWAWPGVVAALWALMEWLRGTLFTGFPWLAVGYSQAPDSPLAGFAPI
VGVYGISLLLMLSAAWLACWLENRQNRRFWLWLGSVWIIGFSLQQIHWTQPEGEPVTVSLLQGNIPQNMKWEPEHLAATM
RTYVRLVQESPSRLIVTPEISFPLYYEQAPRDYLGLLTEHARSRQGDVLIGLVERSPAGDSYYNTMFSFGASPEQSYRKY
HLVPFGEYIPLKPIFGWVIDVLHIPLSDFSRGGLDQQPLNLAGQRVAVNICYEDVFGEEIIMQLPQASLLVNVSNDAWFG
HSIGPHQHLQISQMRALETGRYMLRATNTGVTAIINERGKVLEQLEMFTTAGLHSAAQGFGGATPYVRLGNSLLFGLIGL
LLLTGCLAAFSGKRKTL

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=505, Percent_Identity=37.6237623762376, Blast_Score=301, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 54991; Mature: 54991

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGYYRLIAAFLLGGVTVTGFAPFYFYPAPVATLVLLALLWRTSRTPMQAASTGFAFGMG
CCHHHHHHHHHHHCCCEEECCCCCEECCHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHH
LFGIGVTWLYVSLHDFGHMAPALAVRALIVLCAYLSLFPALAGGIAALRYFRASWAWPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VAALWALMEWLRGTLFTGFPWLAVGYSQAPDSPLAGFAPIVGVYGISLLLMLSAAWLACW
HHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LENRQNRRFWLWLGSVWIIGFSLQQIHWTQPEGEPVTVSLLQGNIPQNMKWEPEHLAATM
HHCCCCCEEEEEECCHHHHEEEHHHEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
RTYVRLVQESPSRLIVTPEISFPLYYEQAPRDYLGLLTEHARSRQGDVLIGLVERSPAGD
HHHHHHHHCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
SYYNTMFSFGASPEQSYRKYHLVPFGEYIPLKPIFGWVIDVLHIPLSDFSRGGLDQQPLN
HHHHHHHHCCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCHH
LAGQRVAVNICYEDVFGEEIIMQLPQASLLVNVSNDAWFGHSIGPHQHLQISQMRALETG
HCCCEEEEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCC
RYMLRATNTGVTAIINERGKVLEQLEMFTTAGLHSAAQGFGGATPYVRLGNSLLFGLIGL
CEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LLLTGCLAAFSGKRKTL
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNGYYRLIAAFLLGGVTVTGFAPFYFYPAPVATLVLLALLWRTSRTPMQAASTGFAFGMG
CCHHHHHHHHHHHCCCEEECCCCCEECCHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHH
LFGIGVTWLYVSLHDFGHMAPALAVRALIVLCAYLSLFPALAGGIAALRYFRASWAWPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VAALWALMEWLRGTLFTGFPWLAVGYSQAPDSPLAGFAPIVGVYGISLLLMLSAAWLACW
HHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LENRQNRRFWLWLGSVWIIGFSLQQIHWTQPEGEPVTVSLLQGNIPQNMKWEPEHLAATM
HHCCCCCEEEEEECCHHHHEEEHHHEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
RTYVRLVQESPSRLIVTPEISFPLYYEQAPRDYLGLLTEHARSRQGDVLIGLVERSPAGD
HHHHHHHHCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
SYYNTMFSFGASPEQSYRKYHLVPFGEYIPLKPIFGWVIDVLHIPLSDFSRGGLDQQPLN
HHHHHHHHCCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCHH
LAGQRVAVNICYEDVFGEEIIMQLPQASLLVNVSNDAWFGHSIGPHQHLQISQMRALETG
HCCCEEEEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCC
RYMLRATNTGVTAIINERGKVLEQLEMFTTAGLHSAAQGFGGATPYVRLGNSLLFGLIGL
CEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LLLTGCLAAFSGKRKTL
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]