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The map label for this gene is rpoC

Identifier: 114331771

GI number: 114331771

Start: 1899317

End: 1903531

Strand: Reverse

Name: rpoC

Synonym: Neut_1794

Alternate gene names: 114331771

Gene position: 1903531-1899317 (Counterclockwise)

Preceding gene: 114331772

Following gene: 114331770

Centisome position: 71.53

GC content: 45.24

Gene sequence:

>4215_bases
GTGAAAGCACTGCTTGATTTATTCAAACAAGTTACACAGAAAGAAGAATTCGATTCCATAAAAATAGGCTTGGCTTCTCC
TGAGAAAATTAGATCATGGTCATATGGAGAGGTAAAAAAACCTGAAACGATAAATTACCGGACCTTCAAGCCTGAAAGAG
ACGGTTTATTTTGTGCCAAAATATTTGGCCCGGTTAAGGATTATGAATGCTTGTGTGGCAAATATAAGCGACTTAAACAC
CGGGGTGTGATATGCGAAAAATGTGGTGTGGAGGTCACCTTATCCAGAATCAGACGGGAGCGCATGGGCCATATTGAACT
GGCTTCGCCTGTTGCCCATATATGGTTCTTAAAATCATTACCTTCACGCCTGGGTCTTGTGCTCGATATAACGTTACGAG
ATATAGAGCGGGTTCTGTATTTTGAGGCCTATATCGTTACTGATCCAGGTATGACACCACTGACTCGTGGTCAGCTTCTG
ACTGAAGATGACTATCTGAATAAAACAGAAGAATTTGGGGATGATTTTAGTGCTGCAATGGGGGCAGAAGGTATTCGTGC
GCTGTTGAATAGTATGGACATCCTGTCGGAAATAGAGTCTTTACGTCTTGAGATCCAAACGACAGGCTCTGAAACTAAGA
TTAAGAAGGCTGCCAAGCGACTCAAGGTGCTTGAGGCGTTTAATAAATCCGGCATGAAGCCGGAGTGGATGATATTGACG
GTATTGCCAGTTCTGCCTCCAGAGCTAAGGCCATTGGTTCCATTGGATGGTGGCCGTTTTGCAACTTCTGATCTTAATGA
TTTATACAGGCGCGTTATAAATCGCAATAATCGTTTGAAGCGGTTGCTGGAATTGCGGGCACCGGAAATTATTATCCGTA
ATGAGAAGCGCATGCTGCAGGAATCGGTGGATTCATTGCTTGATAACGGCCGCCGGGGTAAAGCAATGACGGGAGCAAAT
AAGCGACCGTTAAAATCACTTGCGGATATGATCAAGGGTAAGGGGGGACGTTTCCGTCAAAACCTGCTGGGTAAGCGTGT
TGACTATTCCGGTCGCTCTGTAATTGTGGTAGGGCCGCAACTCAAGCTTCATCAGTGTGGCTTACCGAAAAAAATGGCAT
TGGAATTATTCAAACCGTTTATTTTTAATAAGCTGGAAGTAATGGGAGTGGCGAGCACGATTAAAGCGGCCAAGAGGGAA
GTAGAGAACGAAAATCCGATTGTTTGGGATATTCTGGAAGAAGTTATCCGTGAACATCCGGTAATGCTTAACCGGGCACC
AACTTTACATCGACTCGGTATCCAGGCTTTTGAACCTGTTCTGATTGAAGGAAAGGCAATTCAGTTGCATCCGCTTGTAT
GTGCTGCTTTTAATGCGGACTTTGACGGTGATCAGATGGCGGTGCATGTTCCTTTGTCGCTTGAAGCTCAGATGGAATGC
CGTACGCTGATGTTATCAACTAATAACGTTCTTTCCCCAGCTAATGGCGATCCAATCATAGTTCCTTCCCAGGATATCGT
GCTAGGTCTTTATTATATGACGCGCGAAAAAGTTGGGGCGCAAGGGGAGGGAATGGTTTTTTCAGATGTTTCGGAAATAA
CGCGTGCTTATGAGAGCAAAGCGTTGGAGCTGAATGCCAGAATCACCGTAAGAATCAAGGAAAAGAAAAAATCTTGTGGA
CATGGTGAAGATCCGATTGAAACGATTACACGTTTTGAAACTACCGTTGGCAGGGCGCTCATATCTGAAATCTTGCCAGC
AGGACTTCCTTTCGCCCTAGTCAACAAAACGCTTAAGAAAAAGGAAATTTCCAAGCTTATAAATGCTAGCTTCCGTTTGT
GTGGTTTGCGGGAGACCGTTATATTTGCTGATAAACTTATGTATTCGGGTTTTTCCTATGCGACTCGAGGTGGAATTTCC
ATATGCCTGGATGATCTTGTTACGCCATCACAGAAGACCGGTATTATTCAGGCAGCTGAGCAAGAAATACATGAAATAGC
AAATCAATATATTTCCGGCTTAGTTACTCAAGGAGAGCGTTATAACAAGGTGGTTGATATCTGGGCTCGTGCAGGTGATC
AGGTGGCTAAAGCAATGATGGATCAGCTTAGTGTCGAACCGGTCAAAGATCAAGAGACGGGTGAAATCAGGACAGATAAA
AATGGGCAGGCAGTTACGCAGGAATCATTCAATTCAATTTACATGATGGCTGATTCAGGAGCCCGAGGTTCTGCCGCGCA
GATCCGTCAACTTTCAGGCATGCGTGGTCTTATGGCAAAACCTGATGGCTCTATTATCGAAACCCCGATTACAGCCAATT
TCCGTGAGGGACTTAATATCCTGCAGTATTTTATTTCGACACACGGTGCCAGGAAGGGGCTGGCAGATACAGCACTTAAA
ACTGCTAACTCAGGATATCTCACACGTAGGCTGGTTGATGTGACCCAGGATCTGGTTATCATAGAAAATGACTGTGGTAC
GGATGGTGGTGTCGTAATGAAGGCTTTGGTAGAGGGTGGTAACGTTGTTGAATCCTTGCGTGGGCGAATCTTAGGGCGAG
TAGCGGCGACTGATGTTATAAATCCAGAAACCGGTGAGGTTATTTGCTCGGAAGGTACATTGCTGGATGAAGATACAGCC
GATGAAATTGAAGCTTGTAGTGTTGATGAAGTAAAGGTAAGGACGCCACTCACTTGTGAAACTCGATATGGACTTTGTGC
GAAATGCTATGGGCGTGACCTGGGGCGTGGAACGCCAGTTAATGTTGGAGAAGCCGTGGGAGTGATTGCAGCTCAGTCTA
TTGGTGAACCGGGTACGCAGCTAACCATGCGGACTTTTCATATTGGTGGTGCGGCTTCAAGAGCAGTTGTTGCCAATCAG
GCCGAGAGCAAATCAAACGGAGTTGTCCGTTATTCTCATCATATTCGCTATGTAAAGAATGCACAGAATGAACTAATTAT
AATTTCTCGTAGTGGCGAAATCCTGATCCAGGATGAGAACGGTCGTGAACGTGAGCGGCATAAAATTCCTTATGGTGCGA
CGTTGCATGTGCAAGATGGCGAAACAATCAAGGCAGGGCAAATCCTGGGCTCATGGGAGCCTCATAAACGTCCTATCATA
ACGGAATATGCCGGCAAGATACGGTTTGAGAACGTTGAAGAAGGCGTAACAGTTGTCAGACAAATTGATGAAATAACCGG
GATGGCCACTCTGGTAGTTATAGACCCCAAGCGGCGAAATATTGCGCAATCCAAAGGATTACGGCCGCTTGTTAAGTTTT
TGGATGAAAATGATCAGGAAATCAATATCCCAGGGACTGATCAACCTGTCAGCATTACATTCCACGTTGGTTCTATTATA
ACGGTACGAGATGGACAACAGGTTGGTATTGGTGAGGTTCTGGCTCGTATTCCCCAGGAGACATCCAAGACTCGTGATAT
TACCGGGGGGCTGCCTAGAGTGGCTGAGTTGTTTGAAGCGAGAGTGCCCAAAGATGCTGGTTTCCTTGCTGAAGCTACCG
GCACGGTAGCTTTTGGGAAAGATACCAAAGGGAAACAGCGTCTTGTTATCACTGATCTGGATGGTATTGCACATGAATAT
CTGATTCCTAAGGATAAGCATGTGACTGCGCATGATGGTCAAGTGGTAAATAAGGGTGAGGTGATCGTTGATGGGCCTAT
CGACCCTCATGATATATTGCGACTGCAGGGTGTTGAGGCATTGGCGAAATATATTAGCGATGAGGTTCAAGATGTCTATC
GCCTACAAGGTGTAAGCATCAACGATAAGCATATCGAAGTAATTGTTAGGCAGATGTTGCGCCGTGTCCAGATAACAAAT
GCAGGTGACTCAGCTTTTATTCTTGGAGAGCAGGTCGAGCGTGCTGAGGTTCTTGCCGAGAACGAAAAACTCATTACTGA
AAACAAGATGCCGGCGACCTATGAGTATGTGTTACTGGGGATAACCAAGGCATCTCTTTCTACTGACTCGTTTATTTCTG
CTGCTTCTTTCCAGGAAACAACTCGTGTCTTGACCGAAGCGTCTATCATGGGTAAAAAAGATGATTTGCGAGGTTTGAAG
GAAAATGTAATTGTAGGCAGATTAATACCAGCAGGGACGGGCTTGTCCTTTCATAATATTCGGAAAAAACAAAGATTATC
GGAAAGTACTGTCTATCTGGATGCTGACTTGACGGAGAACGAAATTGCCGAGTGA

Upstream 100 bases:

>100_bases
GTTGATAAGCGCTCTTCTAGCCGCCTTTCAAGATTGAGACTCAAAATTTCCATTTCCTTGGCCTATTTCAGGTTTATACG
TTGATTCACAGGAGTGACAC

Downstream 100 bases:

>100_bases
TGGATGCTGTTAATAATATTGATTATGGTTGATAAGGTCAGAGGCTTTCAAAACTTTTAGCTTCATGTTTTAAAATCTTG
ACTTGTCTCTGATGAGAAAG

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1404; Mature: 1404

Protein sequence:

>1404_residues
MKALLDLFKQVTQKEEFDSIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSRIRRERMGHIELASPVAHIWFLKSLPSRLGLVLDITLRDIERVLYFEAYIVTDPGMTPLTRGQLL
TEDDYLNKTEEFGDDFSAAMGAEGIRALLNSMDILSEIESLRLEIQTTGSETKIKKAAKRLKVLEAFNKSGMKPEWMILT
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPEIIIRNEKRMLQESVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKKMALELFKPFIFNKLEVMGVASTIKAAKRE
VENENPIVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEC
RTLMLSTNNVLSPANGDPIIVPSQDIVLGLYYMTREKVGAQGEGMVFSDVSEITRAYESKALELNARITVRIKEKKKSCG
HGEDPIETITRFETTVGRALISEILPAGLPFALVNKTLKKKEISKLINASFRLCGLRETVIFADKLMYSGFSYATRGGIS
ICLDDLVTPSQKTGIIQAAEQEIHEIANQYISGLVTQGERYNKVVDIWARAGDQVAKAMMDQLSVEPVKDQETGEIRTDK
NGQAVTQESFNSIYMMADSGARGSAAQIRQLSGMRGLMAKPDGSIIETPITANFREGLNILQYFISTHGARKGLADTALK
TANSGYLTRRLVDVTQDLVIIENDCGTDGGVVMKALVEGGNVVESLRGRILGRVAATDVINPETGEVICSEGTLLDEDTA
DEIEACSVDEVKVRTPLTCETRYGLCAKCYGRDLGRGTPVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAVVANQ
AESKSNGVVRYSHHIRYVKNAQNELIIISRSGEILIQDENGRERERHKIPYGATLHVQDGETIKAGQILGSWEPHKRPII
TEYAGKIRFENVEEGVTVVRQIDEITGMATLVVIDPKRRNIAQSKGLRPLVKFLDENDQEINIPGTDQPVSITFHVGSII
TVRDGQQVGIGEVLARIPQETSKTRDITGGLPRVAELFEARVPKDAGFLAEATGTVAFGKDTKGKQRLVITDLDGIAHEY
LIPKDKHVTAHDGQVVNKGEVIVDGPIDPHDILRLQGVEALAKYISDEVQDVYRLQGVSINDKHIEVIVRQMLRRVQITN
AGDSAFILGEQVERAEVLAENEKLITENKMPATYEYVLLGITKASLSTDSFISAASFQETTRVLTEASIMGKKDDLRGLK
ENVIVGRLIPAGTGLSFHNIRKKQRLSESTVYLDADLTENEIAE

Sequences:

>Translated_1404_residues
MKALLDLFKQVTQKEEFDSIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSRIRRERMGHIELASPVAHIWFLKSLPSRLGLVLDITLRDIERVLYFEAYIVTDPGMTPLTRGQLL
TEDDYLNKTEEFGDDFSAAMGAEGIRALLNSMDILSEIESLRLEIQTTGSETKIKKAAKRLKVLEAFNKSGMKPEWMILT
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPEIIIRNEKRMLQESVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKKMALELFKPFIFNKLEVMGVASTIKAAKRE
VENENPIVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEC
RTLMLSTNNVLSPANGDPIIVPSQDIVLGLYYMTREKVGAQGEGMVFSDVSEITRAYESKALELNARITVRIKEKKKSCG
HGEDPIETITRFETTVGRALISEILPAGLPFALVNKTLKKKEISKLINASFRLCGLRETVIFADKLMYSGFSYATRGGIS
ICLDDLVTPSQKTGIIQAAEQEIHEIANQYISGLVTQGERYNKVVDIWARAGDQVAKAMMDQLSVEPVKDQETGEIRTDK
NGQAVTQESFNSIYMMADSGARGSAAQIRQLSGMRGLMAKPDGSIIETPITANFREGLNILQYFISTHGARKGLADTALK
TANSGYLTRRLVDVTQDLVIIENDCGTDGGVVMKALVEGGNVVESLRGRILGRVAATDVINPETGEVICSEGTLLDEDTA
DEIEACSVDEVKVRTPLTCETRYGLCAKCYGRDLGRGTPVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAVVANQ
AESKSNGVVRYSHHIRYVKNAQNELIIISRSGEILIQDENGRERERHKIPYGATLHVQDGETIKAGQILGSWEPHKRPII
TEYAGKIRFENVEEGVTVVRQIDEITGMATLVVIDPKRRNIAQSKGLRPLVKFLDENDQEINIPGTDQPVSITFHVGSII
TVRDGQQVGIGEVLARIPQETSKTRDITGGLPRVAELFEARVPKDAGFLAEATGTVAFGKDTKGKQRLVITDLDGIAHEY
LIPKDKHVTAHDGQVVNKGEVIVDGPIDPHDILRLQGVEALAKYISDEVQDVYRLQGVSINDKHIEVIVRQMLRRVQITN
AGDSAFILGEQVERAEVLAENEKLITENKMPATYEYVLLGITKASLSTDSFISAASFQETTRVLTEASIMGKKDDLRGLK
ENVIVGRLIPAGTGLSFHNIRKKQRLSESTVYLDADLTENEIAE
>Mature_1404_residues
MKALLDLFKQVTQKEEFDSIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSRIRRERMGHIELASPVAHIWFLKSLPSRLGLVLDITLRDIERVLYFEAYIVTDPGMTPLTRGQLL
TEDDYLNKTEEFGDDFSAAMGAEGIRALLNSMDILSEIESLRLEIQTTGSETKIKKAAKRLKVLEAFNKSGMKPEWMILT
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPEIIIRNEKRMLQESVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKKMALELFKPFIFNKLEVMGVASTIKAAKRE
VENENPIVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEC
RTLMLSTNNVLSPANGDPIIVPSQDIVLGLYYMTREKVGAQGEGMVFSDVSEITRAYESKALELNARITVRIKEKKKSCG
HGEDPIETITRFETTVGRALISEILPAGLPFALVNKTLKKKEISKLINASFRLCGLRETVIFADKLMYSGFSYATRGGIS
ICLDDLVTPSQKTGIIQAAEQEIHEIANQYISGLVTQGERYNKVVDIWARAGDQVAKAMMDQLSVEPVKDQETGEIRTDK
NGQAVTQESFNSIYMMADSGARGSAAQIRQLSGMRGLMAKPDGSIIETPITANFREGLNILQYFISTHGARKGLADTALK
TANSGYLTRRLVDVTQDLVIIENDCGTDGGVVMKALVEGGNVVESLRGRILGRVAATDVINPETGEVICSEGTLLDEDTA
DEIEACSVDEVKVRTPLTCETRYGLCAKCYGRDLGRGTPVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAVVANQ
AESKSNGVVRYSHHIRYVKNAQNELIIISRSGEILIQDENGRERERHKIPYGATLHVQDGETIKAGQILGSWEPHKRPII
TEYAGKIRFENVEEGVTVVRQIDEITGMATLVVIDPKRRNIAQSKGLRPLVKFLDENDQEINIPGTDQPVSITFHVGSII
TVRDGQQVGIGEVLARIPQETSKTRDITGGLPRVAELFEARVPKDAGFLAEATGTVAFGKDTKGKQRLVITDLDGIAHEY
LIPKDKHVTAHDGQVVNKGEVIVDGPIDPHDILRLQGVEALAKYISDEVQDVYRLQGVSINDKHIEVIVRQMLRRVQITN
AGDSAFILGEQVERAEVLAENEKLITENKMPATYEYVLLGITKASLSTDSFISAASFQETTRVLTEASIMGKKDDLRGLK
ENVIVGRLIPAGTGLSFHNIRKKQRLSESTVYLDADLTENEIAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI39725938, Length=864, Percent_Identity=26.3888888888889, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI4505939, Length=575, Percent_Identity=25.9130434782609, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI103471997, Length=225, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=1e-15,
Organism=Escherichia coli, GI2367335, Length=1386, Percent_Identity=66.5223665223665, Blast_Score=1877, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=703, Percent_Identity=26.6002844950213, Blast_Score=181, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71987878, Length=346, Percent_Identity=30.9248554913295, Blast_Score=146, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320061, Length=888, Percent_Identity=23.8738738738739, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324690, Length=726, Percent_Identity=24.5179063360882, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281360912, Length=851, Percent_Identity=24.0893066980023, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI17530899, Length=311, Percent_Identity=30.8681672025724, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI17647875, Length=328, Percent_Identity=27.7439024390244, Blast_Score=103, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_NITEC (Q0AF54)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747993.1
- ProteinModelPortal:   Q0AF54
- STRING:   Q0AF54
- GeneID:   4272272
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1794
- NMPDR:   fig|335283.3.peg.76
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q0AF54
- ProtClustDB:   PRK00566
- BioCyc:   NEUT335283:NEUT_1794-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155340; Mature: 155340

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLDLFKQVTQKEEFDSIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSRIRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRLGLVLDITLRDIERVLYFEAYIVTDPGMTPLTRGQLLTEDDYLNKTEEFGDDFSAAM
HHHCCEEEEEHHHHHHHHHHEEEEEEECCCCCCCCCCCEECCCHHCCHHHHHCCHHHHHH
GAEGIRALLNSMDILSEIESLRLEIQTTGSETKIKKAAKRLKVLEAFNKSGMKPEWMILT
CHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPEIIIRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECHHHHHH
ESVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPQ
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEECCC
LKLHQCGLPKKMALELFKPFIFNKLEVMGVASTIKAAKREVENENPIVWDILEEVIREHP
EEEHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEC
EEECCCCCHHHHCHHHCCCEEEECCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCCE
RTLMLSTNNVLSPANGDPIIVPSQDIVLGLYYMTREKVGAQGEGMVFSDVSEITRAYESK
EEEEEECCCEECCCCCCEEEECCCHHEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
ALELNARITVRIKEKKKSCGHGEDPIETITRFETTVGRALISEILPAGLPFALVNKTLKK
EEEEEEEEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KEISKLINASFRLCGLRETVIFADKLMYSGFSYATRGGISICLDDLVTPSQKTGIIQAAE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHCCCCCCCCHHHHHH
QEIHEIANQYISGLVTQGERYNKVVDIWARAGDQVAKAMMDQLSVEPVKDQETGEIRTDK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEECC
NGQAVTQESFNSIYMMADSGARGSAAQIRQLSGMRGLMAKPDGSIIETPITANFREGLNI
CCCEEEHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHH
LQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVIIENDCGTDGGVVMKALVEGG
HHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCC
NVVESLRGRILGRVAATDVINPETGEVICSEGTLLDEDTADEIEACSVDEVKVRTPLTCE
HHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHCCCCCEEECCCCEEC
TRYGLCAKCYGRDLGRGTPVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAVVANQ
CCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHCC
AESKSNGVVRYSHHIRYVKNAQNELIIISRSGEILIQDENGRERERHKIPYGATLHVQDG
CCCCCCCEEEEHHHHHHHCCCCCCEEEEECCCCEEEECCCCCHHHHHCCCCCEEEEECCC
ETIKAGQILGSWEPHKRPIITEYAGKIRFENVEEGVTVVRQIDEITGMATLVVIDPKRRN
CEEEECCEECCCCCCCCCCHHHHCCCEEECCHHHHHHHHHHHHHHCCEEEEEEECCCHHH
IAQSKGLRPLVKFLDENDQEINIPGTDQPVSITFHVGSIITVRDGQQVGIGEVLARIPQE
HHHHCCCHHHHHHHCCCCCEEECCCCCCCEEEEEEECEEEEECCCCCCCHHHHHHHCCHH
TSKTRDITGGLPRVAELFEARVPKDAGFLAEATGTVAFGKDTKGKQRLVITDLDGIAHEY
HCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCEEECCCCCCCCEEEEEECCCHHHHH
LIPKDKHVTAHDGQVVNKGEVIVDGPIDPHDILRLQGVEALAKYISDEVQDVYRLQGVSI
CCCCCCEEECCCCEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NDKHIEVIVRQMLRRVQITNAGDSAFILGEQVERAEVLAENEKLITENKMPATYEYVLLG
CHHHHHHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHCCCCEEECCCCCCEEEEEEEE
ITKASLSTDSFISAASFQETTRVLTEASIMGKKDDLRGLKENVIVGRLIPAGTGLSFHNI
EEHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCCHHHH
RKKQRLSESTVYLDADLTENEIAE
HHHHHCCCCEEEEECCCCHHHCCC
>Mature Secondary Structure
MKALLDLFKQVTQKEEFDSIKIGLASPEKIRSWSYGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSRIRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRLGLVLDITLRDIERVLYFEAYIVTDPGMTPLTRGQLLTEDDYLNKTEEFGDDFSAAM
HHHCCEEEEEHHHHHHHHHHEEEEEEECCCCCCCCCCCEECCCHHCCHHHHHCCHHHHHH
GAEGIRALLNSMDILSEIESLRLEIQTTGSETKIKKAAKRLKVLEAFNKSGMKPEWMILT
CHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPEIIIRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECHHHHHH
ESVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPQ
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEECCC
LKLHQCGLPKKMALELFKPFIFNKLEVMGVASTIKAAKREVENENPIVWDILEEVIREHP
EEEHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEC
EEECCCCCHHHHCHHHCCCEEEECCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCCE
RTLMLSTNNVLSPANGDPIIVPSQDIVLGLYYMTREKVGAQGEGMVFSDVSEITRAYESK
EEEEEECCCEECCCCCCEEEECCCHHEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
ALELNARITVRIKEKKKSCGHGEDPIETITRFETTVGRALISEILPAGLPFALVNKTLKK
EEEEEEEEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KEISKLINASFRLCGLRETVIFADKLMYSGFSYATRGGISICLDDLVTPSQKTGIIQAAE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHCCCCCCCCHHHHHH
QEIHEIANQYISGLVTQGERYNKVVDIWARAGDQVAKAMMDQLSVEPVKDQETGEIRTDK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEECC
NGQAVTQESFNSIYMMADSGARGSAAQIRQLSGMRGLMAKPDGSIIETPITANFREGLNI
CCCEEEHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHH
LQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVIIENDCGTDGGVVMKALVEGG
HHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCC
NVVESLRGRILGRVAATDVINPETGEVICSEGTLLDEDTADEIEACSVDEVKVRTPLTCE
HHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHCCCCCEEECCCCEEC
TRYGLCAKCYGRDLGRGTPVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAVVANQ
CCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHCC
AESKSNGVVRYSHHIRYVKNAQNELIIISRSGEILIQDENGRERERHKIPYGATLHVQDG
CCCCCCCEEEEHHHHHHHCCCCCCEEEEECCCCEEEECCCCCHHHHHCCCCCEEEEECCC
ETIKAGQILGSWEPHKRPIITEYAGKIRFENVEEGVTVVRQIDEITGMATLVVIDPKRRN
CEEEECCEECCCCCCCCCCHHHHCCCEEECCHHHHHHHHHHHHHHCCEEEEEEECCCHHH
IAQSKGLRPLVKFLDENDQEINIPGTDQPVSITFHVGSIITVRDGQQVGIGEVLARIPQE
HHHHCCCHHHHHHHCCCCCEEECCCCCCCEEEEEEECEEEEECCCCCCCHHHHHHHCCHH
TSKTRDITGGLPRVAELFEARVPKDAGFLAEATGTVAFGKDTKGKQRLVITDLDGIAHEY
HCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCEEECCCCCCCCEEEEEECCCHHHHH
LIPKDKHVTAHDGQVVNKGEVIVDGPIDPHDILRLQGVEALAKYISDEVQDVYRLQGVSI
CCCCCCEEECCCCEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NDKHIEVIVRQMLRRVQITNAGDSAFILGEQVERAEVLAENEKLITENKMPATYEYVLLG
CHHHHHHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHCCCCEEECCCCCCEEEEEEEE
ITKASLSTDSFISAASFQETTRVLTEASIMGKKDDLRGLKENVIVGRLIPAGTGLSFHNI
EEHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCCHHHH
RKKQRLSESTVYLDADLTENEIAE
HHHHHCCCCEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA