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The map label for this gene is recD [H]

Identifier: 114331348

GI number: 114331348

Start: 1427146

End: 1429188

Strand: Direct

Name: recD [H]

Synonym: Neut_1357

Alternate gene names: 114331348

Gene position: 1427146-1429188 (Clockwise)

Preceding gene: 114331347

Following gene: 114331356

Centisome position: 53.63

GC content: 53.26

Gene sequence:

>2043_bases
ATGAGCACTCCAGCAACAAACCCGCAGGAAATACTGGCTCTGCTGGAAAGCTGGGTTACCCGTGGCTGGCTGCGCGAGCT
GGATCTTGCCTTGGTACGTTTTTTAAAAACTGAAGTTCCTGCTATGGATCCGGTATTGATGCTGGCAACCGCTCTGGTCA
GTCACCAACTGGGGCGAGGTCATGTTTGTCTGGATCTGGACAATCTCTTAAGCGATCCTTGTACGGCGTTGTCGTTGCCC
TCTGGCCAGAATGAGCCCTCTGCCAGAAAAGAAATTCAGCATATCAGCGTTCTTCTGGCGGACTGGAAAGCATCCGGCTG
GCTTACGCAACAAACGGAACTGATCAGCAAGGATGAGAGAAATACACCGCTGGTGCTTGCTGGCCCTCGTCTGTATCTGC
GCCGCTACTGGCGTTATGAACGTCAGGTGGAAGCTGCTATCTACCAGCGGCTGACCAGTAGTCAGCAGATTGTCAGCCAG
TTGCCTGAAATTGAGTTCAAAGACAAACTGAATGCACTTTTTCCACCCAGCGGTACCACGTATACACAAACAGACTGGCA
AAAAATCGCTTGTGCACTTGCTGCCCGCAGTGCATTCAGTATCATCACCGGCGGGCCAGGAACCGGAAAAACGACCACTG
TAGTTCGTCTGCTGGCACTGCTGCAATCGATTGCGCTCATCCAGCATCCGGAATGCCTCCTTAAAATCTGCCTGGCCGCC
CCTACTGGCAAGGCAGCAGCACGCCTCAAGGAATCCATTACCGGCGCCATCGACAAGCTGCCCGCTTTTATTCAGGACGA
TACCACGCTGAAAACGAGCATCCCAAGCAACGTGACAACCCTGCACCGTTTGCTGGGCTCGCGTCCGGATTCCCGGCTGT
TCCGGCATGATGCACGCCACCCGTTGCCACTGGATGTACTGGTGATTGATGAGGGCTCCATGATTGATCTGGAAATGATG
GCAGCCGTACTCCTTGCCTTGCCCCCTCACGCTCGCCTGGTTATCCTGGGAGACAAGGATCAACTGGCTTCTGTTGAAGC
AGGTTCTGTGCTGGGTGCCTTGTGCCACCGGGCTCAGCAAGGGCATTTCCAGCCTGAAACTGCCCAATGGGTTGAAACGG
CCACCGGAGAAAAGATTGATCCCGTTCTGCTGGATACAAACGGCTTGCCACTTGACCAGCATATTGTGATGTTGCGGACA
AACTGGCGATTTGATGCTGCCAGCGGCATCGGGCAACTGGCCCGTGCAGTCAATACTGCTGATTCGGAAACCATTCGCAC
AATCTGGATGCAAGGCTATGATGACTTGTTCCGTCATAATTTACCTGATCTCGAAGATAGCCGCCTGGCAACCATCCTGC
TCGGCCAATCTGGAGAAAAAGATACACCGCAAGGAATTGCGGGTTATCTGGGCATCATTAAAGCAGAGCGGCCACCACTG
GATGCAGAAAAAGTTGCATTTGATGCCTGGGCGCATCAGGTGTTGCAATCGCACGGCCGTTTTCAGTTGCTGTGTGCGCT
CAGAAATGGCCCATTTGGGGTCAGCGGCATGAATCAGCATATTGAAGCACTGCTGGCCAGACACCAGTTGATTAAACCTG
GCAGCATCTGGTATGAAGGGCGCCCGGTACTGGTCACCCGCAATGATTATGCGCTTGGTTTGATGAACGGGGACATCGGG
ATAGCGCTCAGCTATCCCACGCCTAACAGGACAACCGGAAAACTGGAATGGGGTATACGGGTTGCCTTTGCCAGAGGAAA
TGGCAGCGGTGGTATTCACTGGGTGCTGCCCAGTCGTCTCTTGTCAATCGAAACTGTTTTTGCACTGACTGTTCACAAAT
CACAAGGCTCGGAATTTGAGCATTGTGCCCTGCTGCTACCACCCGAACTGAATCCCGTTCTGACACGAGAGTTGATCTAT
ACCGGCATCACCCGGGGAAAACGCTGGTTATCCATCATTTGTACCGGAAACAGCAATATTATTGATCAAGCCGTTTCCAG
AACGGTCCAGCGCTCCGGCGGATTGTTTGCCGGATCATCCTGA

Upstream 100 bases:

>100_bases
GGATTGATGCACCCACAGCCGGTGTCCATTTTGAACGCCCCCCGGGAACGTTAATGGACACGCTGGATGAGCTATTTGCC
GGGAAGACAGAAGGTAGCGC

Downstream 100 bases:

>100_bases
TCAGGAGCGGCTGGTACGCTAACTCAATAAAAACTGTTTCAACACTTTGATCATATATTCGTGATCCTGCACGCCCGCGC
TCTCCCGGATGCTGTGCATG

Product: exodeoxyribonuclease V, alpha subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 680; Mature: 679

Protein sequence:

>680_residues
MSTPATNPQEILALLESWVTRGWLRELDLALVRFLKTEVPAMDPVLMLATALVSHQLGRGHVCLDLDNLLSDPCTALSLP
SGQNEPSARKEIQHISVLLADWKASGWLTQQTELISKDERNTPLVLAGPRLYLRRYWRYERQVEAAIYQRLTSSQQIVSQ
LPEIEFKDKLNALFPPSGTTYTQTDWQKIACALAARSAFSIITGGPGTGKTTTVVRLLALLQSIALIQHPECLLKICLAA
PTGKAAARLKESITGAIDKLPAFIQDDTTLKTSIPSNVTTLHRLLGSRPDSRLFRHDARHPLPLDVLVIDEGSMIDLEMM
AAVLLALPPHARLVILGDKDQLASVEAGSVLGALCHRAQQGHFQPETAQWVETATGEKIDPVLLDTNGLPLDQHIVMLRT
NWRFDAASGIGQLARAVNTADSETIRTIWMQGYDDLFRHNLPDLEDSRLATILLGQSGEKDTPQGIAGYLGIIKAERPPL
DAEKVAFDAWAHQVLQSHGRFQLLCALRNGPFGVSGMNQHIEALLARHQLIKPGSIWYEGRPVLVTRNDYALGLMNGDIG
IALSYPTPNRTTGKLEWGIRVAFARGNGSGGIHWVLPSRLLSIETVFALTVHKSQGSEFEHCALLLPPELNPVLTRELIY
TGITRGKRWLSIICTGNSNIIDQAVSRTVQRSGGLFAGSS

Sequences:

>Translated_680_residues
MSTPATNPQEILALLESWVTRGWLRELDLALVRFLKTEVPAMDPVLMLATALVSHQLGRGHVCLDLDNLLSDPCTALSLP
SGQNEPSARKEIQHISVLLADWKASGWLTQQTELISKDERNTPLVLAGPRLYLRRYWRYERQVEAAIYQRLTSSQQIVSQ
LPEIEFKDKLNALFPPSGTTYTQTDWQKIACALAARSAFSIITGGPGTGKTTTVVRLLALLQSIALIQHPECLLKICLAA
PTGKAAARLKESITGAIDKLPAFIQDDTTLKTSIPSNVTTLHRLLGSRPDSRLFRHDARHPLPLDVLVIDEGSMIDLEMM
AAVLLALPPHARLVILGDKDQLASVEAGSVLGALCHRAQQGHFQPETAQWVETATGEKIDPVLLDTNGLPLDQHIVMLRT
NWRFDAASGIGQLARAVNTADSETIRTIWMQGYDDLFRHNLPDLEDSRLATILLGQSGEKDTPQGIAGYLGIIKAERPPL
DAEKVAFDAWAHQVLQSHGRFQLLCALRNGPFGVSGMNQHIEALLARHQLIKPGSIWYEGRPVLVTRNDYALGLMNGDIG
IALSYPTPNRTTGKLEWGIRVAFARGNGSGGIHWVLPSRLLSIETVFALTVHKSQGSEFEHCALLLPPELNPVLTRELIY
TGITRGKRWLSIICTGNSNIIDQAVSRTVQRSGGLFAGSS
>Mature_679_residues
STPATNPQEILALLESWVTRGWLRELDLALVRFLKTEVPAMDPVLMLATALVSHQLGRGHVCLDLDNLLSDPCTALSLPS
GQNEPSARKEIQHISVLLADWKASGWLTQQTELISKDERNTPLVLAGPRLYLRRYWRYERQVEAAIYQRLTSSQQIVSQL
PEIEFKDKLNALFPPSGTTYTQTDWQKIACALAARSAFSIITGGPGTGKTTTVVRLLALLQSIALIQHPECLLKICLAAP
TGKAAARLKESITGAIDKLPAFIQDDTTLKTSIPSNVTTLHRLLGSRPDSRLFRHDARHPLPLDVLVIDEGSMIDLEMMA
AVLLALPPHARLVILGDKDQLASVEAGSVLGALCHRAQQGHFQPETAQWVETATGEKIDPVLLDTNGLPLDQHIVMLRTN
WRFDAASGIGQLARAVNTADSETIRTIWMQGYDDLFRHNLPDLEDSRLATILLGQSGEKDTPQGIAGYLGIIKAERPPLD
AEKVAFDAWAHQVLQSHGRFQLLCALRNGPFGVSGMNQHIEALLARHQLIKPGSIWYEGRPVLVTRNDYALGLMNGDIGI
ALSYPTPNRTTGKLEWGIRVAFARGNGSGGIHWVLPSRLLSIETVFALTVHKSQGSEFEHCALLLPPELNPVLTRELIYT
GITRGKRWLSIICTGNSNIIDQAVSRTVQRSGGLFAGSS

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=666, Percent_Identity=41.2912912912913, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 74645; Mature: 74514

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPATNPQEILALLESWVTRGWLRELDLALVRFLKTEVPAMDPVLMLATALVSHQLGRG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
HVCLDLDNLLSDPCTALSLPSGQNEPSARKEIQHISVLLADWKASGWLTQQTELISKDER
CEEEEHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
NTPLVLAGPRLYLRRYWRYERQVEAAIYQRLTSSQQIVSQLPEIEFKDKLNALFPPSGTT
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHCCEECCCCCCC
YTQTDWQKIACALAARSAFSIITGGPGTGKTTTVVRLLALLQSIALIQHPECLLKICLAA
CCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
PTGKAAARLKESITGAIDKLPAFIQDDTTLKTSIPSNVTTLHRLLGSRPDSRLFRHDARH
CCCHHHHHHHHHHHHHHHHCCHHHCCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHCCCC
PLPLDVLVIDEGSMIDLEMMAAVLLALPPHARLVILGDKDQLASVEAGSVLGALCHRAQQ
CCCEEEEEECCCCEECHHHHHHHHHHCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHC
GHFQPETAQWVETATGEKIDPVLLDTNGLPLDQHIVMLRTNWRFDAASGIGQLARAVNTA
CCCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCC
DSETIRTIWMQGYDDLFRHNLPDLEDSRLATILLGQSGEKDTPQGIAGYLGIIKAERPPL
CHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHEECCCCCC
DAEKVAFDAWAHQVLQSHGRFQLLCALRNGPFGVSGMNQHIEALLARHQLIKPGSIWYEG
CHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECC
RPVLVTRNDYALGLMNGDIGIALSYPTPNRTTGKLEWGIRVAFARGNGSGGIHWVLPSRL
EEEEEECCCEEEEEEECCEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCEEEECHHHH
LSIETVFALTVHKSQGSEFEHCALLLPPELNPVLTRELIYTGITRGKRWLSIICTGNSNI
HHHEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHH
IDQAVSRTVQRSGGLFAGSS
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STPATNPQEILALLESWVTRGWLRELDLALVRFLKTEVPAMDPVLMLATALVSHQLGRG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
HVCLDLDNLLSDPCTALSLPSGQNEPSARKEIQHISVLLADWKASGWLTQQTELISKDER
CEEEEHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
NTPLVLAGPRLYLRRYWRYERQVEAAIYQRLTSSQQIVSQLPEIEFKDKLNALFPPSGTT
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHCCEECCCCCCC
YTQTDWQKIACALAARSAFSIITGGPGTGKTTTVVRLLALLQSIALIQHPECLLKICLAA
CCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
PTGKAAARLKESITGAIDKLPAFIQDDTTLKTSIPSNVTTLHRLLGSRPDSRLFRHDARH
CCCHHHHHHHHHHHHHHHHCCHHHCCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHCCCC
PLPLDVLVIDEGSMIDLEMMAAVLLALPPHARLVILGDKDQLASVEAGSVLGALCHRAQQ
CCCEEEEEECCCCEECHHHHHHHHHHCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHC
GHFQPETAQWVETATGEKIDPVLLDTNGLPLDQHIVMLRTNWRFDAASGIGQLARAVNTA
CCCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCC
DSETIRTIWMQGYDDLFRHNLPDLEDSRLATILLGQSGEKDTPQGIAGYLGIIKAERPPL
CHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHEECCCCCC
DAEKVAFDAWAHQVLQSHGRFQLLCALRNGPFGVSGMNQHIEALLARHQLIKPGSIWYEG
CHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECC
RPVLVTRNDYALGLMNGDIGIALSYPTPNRTTGKLEWGIRVAFARGNGSGGIHWVLPSRL
EEEEEECCCEEEEEEECCEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCEEEECHHHH
LSIETVFALTVHKSQGSEFEHCALLLPPELNPVLTRELIYTGITRGKRWLSIICTGNSNI
HHHEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHH
IDQAVSRTVQRSGGLFAGSS
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]