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The map label for this gene is merD

Identifier: 114331303

GI number: 114331303

Start: 1372939

End: 1373304

Strand: Direct

Name: merD

Synonym: Neut_1310

Alternate gene names: 114331303

Gene position: 1372939-1373304 (Clockwise)

Preceding gene: 114331302

Following gene: 114331304

Centisome position: 51.59

GC content: 67.49

Gene sequence:

>366_bases
ATGAGCGCCTACACAGTGTCCCGGCTGGCCCTTGATGCCGGGGTGAGCGTGCATATCGTGCGCGACTACCTGCTGCGCGG
ATTGCTACGGCCGGTCGCGTGCACCACGGGCGGCTACGGCTTGTTCGATGACACCGCGTTGCAACGGCTGCGCTTTGTAC
GGGCTGCCTTCGAAGCGGGTATCGGCCTGGACGCACTGGCGCGGCTGTGCCGGGCGCTGGATGCTGCGGACGGTGACGGT
GCGTCTGCGCAGCTTGCCGTGTTGCGGCAACTCGTCGAGCGTCGGCGCGAGGCCCTGGCCAGCCTCGAAATGCAACTGGC
CGCCATGCCAACCGAACCGGCACAGCACGCGGAGAGTCTGCCATGA

Upstream 100 bases:

>100_bases
ACCTGACCATGGTCGAAGGGCTGAAGCTCGCGGCGCAGACCTTCAGCAAGGACGTGAAGCAGCTTTCGTGCTGCGCCGGA
TGAGGAAAAGGAGGTGTTCA

Downstream 100 bases:

>100_bases
ACAGCCCAGAGCACTTGCCGTCTGAGACGCACAAACCGATCACCGGCTACTTGTGGGGCGCGCTGGCCGTGCTCACCTGT
CCCTGCCATTTGCCGATTCT

Product: transcriptional regulator MerD

Products: NA

Alternate protein names: Mercuric resistance protein merD

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSAYTVSRLALDAGVSVHIVRDYLLRGLLRPVACTTGGYGLFDDTALQRLRFVRAAFEAGIGLDALARLCRALDAADGDG
ASAQLAVLRQLVERRREALASLEMQLAAMPTEPAQHAESLP

Sequences:

>Translated_121_residues
MSAYTVSRLALDAGVSVHIVRDYLLRGLLRPVACTTGGYGLFDDTALQRLRFVRAAFEAGIGLDALARLCRALDAADGDG
ASAQLAVLRQLVERRREALASLEMQLAAMPTEPAQHAESLP
>Mature_120_residues
SAYTVSRLALDAGVSVHIVRDYLLRGLLRPVACTTGGYGLFDDTALQRLRFVRAAFEAGIGLDALARLCRALDAADGDGA
SAQLAVLRQLVERRREALASLEMQLAAMPTEPAQHAESLP

Specific function: Unknown

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MERD_ACICA (Q52110)

Other databases:

- EMBL:   AF213017
- ProteinModelPortal:   Q52110
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011797
- PRINTS:   PR00040
- SMART:   SM00422
- TIGRFAMs:   TIGR02054

Pfam domain/function: SSF46955 Putativ_DNA_bind

EC number: NA

Molecular weight: Translated: 12966; Mature: 12835

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00552 HTH_MERR_1; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAYTVSRLALDAGVSVHIVRDYLLRGLLRPVACTTGGYGLFDDTALQRLRFVRAAFEAG
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
IGLDALARLCRALDAADGDGASAQLAVLRQLVERRREALASLEMQLAAMPTEPAQHAESL
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
P
C
>Mature Secondary Structure 
SAYTVSRLALDAGVSVHIVRDYLLRGLLRPVACTTGGYGLFDDTALQRLRFVRAAFEAG
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
IGLDALARLCRALDAADGDGASAQLAVLRQLVERRREALASLEMQLAAMPTEPAQHAESL
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8302940; 9159519