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The map label for this gene is regA [H]

Identifier: 114331247

GI number: 114331247

Start: 1307874

End: 1308407

Strand: Direct

Name: regA [H]

Synonym: Neut_1251

Alternate gene names: 114331247

Gene position: 1307874-1308407 (Clockwise)

Preceding gene: 114331246

Following gene: 114331250

Centisome position: 49.15

GC content: 45.69

Gene sequence:

>534_bases
ATGGATCGCCCAAGCCTGTTAATTGTAGATGATGATGAAGTTTTTTGTGATGTACTGGCAAGGGCGATGACAAAGCGCGG
GTTTGACACCACTTGTACACATAACATTAAAACTGCGATCGAACAGGCGGAATCACTCATACCGGAATATGCCATCATTG
ACCTCAAATTGAATAATGAATCCGGTTTATCACTTGTTGAAAAAATCAGGGAACTGGATCCTGGAACCCGCATTATCGTC
CTAACCGGCTACGCCAGTATTGCGACTGCAGTCGAAGCCATCAAATTGGGAGCAACCCATTATCTGGCAAAACCGGTAGA
CGCGGATGATATCATGGCAGCGTTTGAGCGCACGGCAGGAAATACTGATATACCGATTAGCCCTCACCCTCTATCAGTAG
AGCGCTTGGAATGGGAATATATTCATCGTATTCTTGCAGAGAACGATGATAATATTTCTGCCACCGCCAAGGCACTAAAC
ATGCATCGCAGAACCTTGCAGCGTAAACTCTCAAAAAAACCGGTGCAGCTTTAG

Upstream 100 bases:

>100_bases
ATCGACCCGAAGGAGGGGCATGTACTCATGTCACCATTCCGGTTTCGCACAGAACAACCAGTACTTCACTATGAAAGGAG
AATGCCCTGTGAATGATTCC

Downstream 100 bases:

>100_bases
TTTCTGCTCCGCTTGACAGATATACACCCGCGCGTTGCGAGTGTATATCTGTCAGCAACTGATTCTGATCAAATGCAAGT
TAGAGTTCTGGCCATCGGGA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MDRPSLLIVDDDEVFCDVLARAMTKRGFDTTCTHNIKTAIEQAESLIPEYAIIDLKLNNESGLSLVEKIRELDPGTRIIV
LTGYASIATAVEAIKLGATHYLAKPVDADDIMAAFERTAGNTDIPISPHPLSVERLEWEYIHRILAENDDNISATAKALN
MHRRTLQRKLSKKPVQL

Sequences:

>Translated_177_residues
MDRPSLLIVDDDEVFCDVLARAMTKRGFDTTCTHNIKTAIEQAESLIPEYAIIDLKLNNESGLSLVEKIRELDPGTRIIV
LTGYASIATAVEAIKLGATHYLAKPVDADDIMAAFERTAGNTDIPISPHPLSVERLEWEYIHRILAENDDNISATAKALN
MHRRTLQRKLSKKPVQL
>Mature_177_residues
MDRPSLLIVDDDEVFCDVLARAMTKRGFDTTCTHNIKTAIEQAESLIPEYAIIDLKLNNESGLSLVEKIRELDPGTRIIV
LTGYASIATAVEAIKLGATHYLAKPVDADDIMAAFERTAGNTDIPISPHPLSVERLEWEYIHRILAENDDNISATAKALN
MHRRTLQRKLSKKPVQL

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=121, Percent_Identity=30.5785123966942, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=32.1428571428571, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=32.4786324786325, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR002197
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 19722; Mature: 19722

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRPSLLIVDDDEVFCDVLARAMTKRGFDTTCTHNIKTAIEQAESLIPEYAIIDLKLNNE
CCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCC
SGLSLVEKIRELDPGTRIIVLTGYASIATAVEAIKLGATHYLAKPVDADDIMAAFERTAG
CCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCC
NTDIPISPHPLSVERLEWEYIHRILAENDDNISATAKALNMHRRTLQRKLSKKPVQL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDRPSLLIVDDDEVFCDVLARAMTKRGFDTTCTHNIKTAIEQAESLIPEYAIIDLKLNNE
CCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCC
SGLSLVEKIRELDPGTRIIVLTGYASIATAVEAIKLGATHYLAKPVDADDIMAAFERTAG
CCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCC
NTDIPISPHPLSVERLEWEYIHRILAENDDNISATAKALNMHRRTLQRKLSKKPVQL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA