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The map label for this gene is cheB [H]

Identifier: 114331171

GI number: 114331171

Start: 1223882

End: 1224949

Strand: Direct

Name: cheB [H]

Synonym: Neut_1173

Alternate gene names: 114331171

Gene position: 1223882-1224949 (Clockwise)

Preceding gene: 114331170

Following gene: 114331172

Centisome position: 45.99

GC content: 52.06

Gene sequence:

>1068_bases
ATGAAAAAAATCAGTGTGCTTGTTATCGATGATTCTGCCTTGATTCGTAAATTACTGGCCGAGATCATCAATAGCCAATC
GGATATGGAAGTAATCGGGGCAGCACCGGATCCACTGGTAGCGCGTGAAATGATCCGGACATTGAATCCGGATGTGCTGA
CATTGGATGTGGAAATGCCCAAAATGGACGGGCTGGAATTTCTGGAAAAACTGATGCGGTTGCGGCCCATGCCGGTAGTG
ATGGTTTCTACGCTGACCGAATGTGGCTCGGAAACGACTTTCCGCGCACTTGAACTAGGCGCAATCGATTTTGTTGCCAA
GCCCAAAATGGATATTCGCCATGGCCTCGAAGCTTATGGTAGCGAGATTGCCAGCAAAATTCGCATTGCCAGCACAGCAC
GTATCCGTCGCCTGGAGCCTGGCGCTGCTGCGAGTGGTAGAGCTTTACAGATTCCGCGCCATCATAGTATCTCAACCGAA
AAGCTGATTATTATCGGTGCATCTACGGGCGGTACCGAAGCCATCAAGGATGTGCTGATTCATTTTCCGCCGGATTGTCC
AGGTATTCTGATTGCCCAGCACATGCCGGAAGGATTTACCCGTTCTTTCGCTGAACGGCTGGATCGGCTCTGCAGAATCC
GGGTAACGGAATCCGAAGGAGGGGAGCGTGTTTTACCGGGCCATGCCTATATTGCGCCGGGCCATTCTCATCTCCTGCTG
AAAAAGAGTGGAGCCAATTATATTACCGAGCTGAGTCAGGCAGATCCGGTCAACCGCCATCGCCCATCCGTGGATGTACT
GTTTCAGTCTGCTGCACAGTGCGCTGGGAAGAATGCGGTTGGTGTGATTCTGACAGGCATGGGCAAGGATGGTGCAGTAG
GAATGCTGGCAATGCATCATGCAGGTGCCTATAACCTGGCACAGGATGAAGCCAGTTGCGTGGTGTTCGGTATGCCCCGG
GAAGCAATTGCTGTTGGTGCGACTGATGAAGTGGTGCCCTTGCAGGATATGGCCTCACACATCCTGGCAAAACTGACTGG
TACAGTCAGGCAAGCTGTTCGTATCTGA

Upstream 100 bases:

>100_bases
CGATACCATTGCCAAGCGTGAGAAACATTACAGCCGGTTACTGCTATCCACAGTAAAACCGGGAATATAGACGAATTCTC
CTGAATATTGAGGGGTACCC

Downstream 100 bases:

>100_bases
TGTTATTCAAGGTGTTTAGCTAAAAGAAAGTTTTTTATTTGTTTATACTAGCTCACCGAAACGTACATACAAGATAATCA
ATGGTAAGCCAATTATACTG

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKKISVLVIDDSALIRKLLAEIINSQSDMEVIGAAPDPLVAREMIRTLNPDVLTLDVEMPKMDGLEFLEKLMRLRPMPVV
MVSTLTECGSETTFRALELGAIDFVAKPKMDIRHGLEAYGSEIASKIRIASTARIRRLEPGAAASGRALQIPRHHSISTE
KLIIIGASTGGTEAIKDVLIHFPPDCPGILIAQHMPEGFTRSFAERLDRLCRIRVTESEGGERVLPGHAYIAPGHSHLLL
KKSGANYITELSQADPVNRHRPSVDVLFQSAAQCAGKNAVGVILTGMGKDGAVGMLAMHHAGAYNLAQDEASCVVFGMPR
EAIAVGATDEVVPLQDMASHILAKLTGTVRQAVRI

Sequences:

>Translated_355_residues
MKKISVLVIDDSALIRKLLAEIINSQSDMEVIGAAPDPLVAREMIRTLNPDVLTLDVEMPKMDGLEFLEKLMRLRPMPVV
MVSTLTECGSETTFRALELGAIDFVAKPKMDIRHGLEAYGSEIASKIRIASTARIRRLEPGAAASGRALQIPRHHSISTE
KLIIIGASTGGTEAIKDVLIHFPPDCPGILIAQHMPEGFTRSFAERLDRLCRIRVTESEGGERVLPGHAYIAPGHSHLLL
KKSGANYITELSQADPVNRHRPSVDVLFQSAAQCAGKNAVGVILTGMGKDGAVGMLAMHHAGAYNLAQDEASCVVFGMPR
EAIAVGATDEVVPLQDMASHILAKLTGTVRQAVRI
>Mature_355_residues
MKKISVLVIDDSALIRKLLAEIINSQSDMEVIGAAPDPLVAREMIRTLNPDVLTLDVEMPKMDGLEFLEKLMRLRPMPVV
MVSTLTECGSETTFRALELGAIDFVAKPKMDIRHGLEAYGSEIASKIRIASTARIRRLEPGAAASGRALQIPRHHSISTE
KLIIIGASTGGTEAIKDVLIHFPPDCPGILIAQHMPEGFTRSFAERLDRLCRIRVTESEGGERVLPGHAYIAPGHSHLLL
KKSGANYITELSQADPVNRHRPSVDVLFQSAAQCAGKNAVGVILTGMGKDGAVGMLAMHHAGAYNLAQDEASCVVFGMPR
EAIAVGATDEVVPLQDMASHILAKLTGTVRQAVRI

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=355, Percent_Identity=62.8169014084507, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38268; Mature: 38268

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKISVLVIDDSALIRKLLAEIINSQSDMEVIGAAPDPLVAREMIRTLNPDVLTLDVEMP
CCEEEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEEEECCC
KMDGLEFLEKLMRLRPMPVVMVSTLTECGSETTFRALELGAIDFVAKPKMDIRHGLEAYG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHEECCCCEECCCCHHHHHHHHHHH
SEIASKIRIASTARIRRLEPGAAASGRALQIPRHHSISTEKLIIIGASTGGTEAIKDVLI
HHHHHHHHHHHHHHHEECCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHH
HFPPDCPGILIAQHMPEGFTRSFAERLDRLCRIRVTESEGGERVLPGHAYIAPGHSHLLL
CCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCEECCCCEEECCCCCEEEE
KKSGANYITELSQADPVNRHRPSVDVLFQSAAQCAGKNAVGVILTGMGKDGAVGMLAMHH
EECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECC
AGAYNLAQDEASCVVFGMPREAIAVGATDEVVPLQDMASHILAKLTGTVRQAVRI
CCCCCCCCCCCCEEEEECCHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKISVLVIDDSALIRKLLAEIINSQSDMEVIGAAPDPLVAREMIRTLNPDVLTLDVEMP
CCEEEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEEEECCC
KMDGLEFLEKLMRLRPMPVVMVSTLTECGSETTFRALELGAIDFVAKPKMDIRHGLEAYG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHEECCCCEECCCCHHHHHHHHHHH
SEIASKIRIASTARIRRLEPGAAASGRALQIPRHHSISTEKLIIIGASTGGTEAIKDVLI
HHHHHHHHHHHHHHHEECCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHH
HFPPDCPGILIAQHMPEGFTRSFAERLDRLCRIRVTESEGGERVLPGHAYIAPGHSHLLL
CCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCEECCCCEEECCCCCEEEE
KKSGANYITELSQADPVNRHRPSVDVLFQSAAQCAGKNAVGVILTGMGKDGAVGMLAMHH
EECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECC
AGAYNLAQDEASCVVFGMPREAIAVGATDEVVPLQDMASHILAKLTGTVRQAVRI
CCCCCCCCCCCCEEEEECCHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]