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The map label for this gene is minC [H]

Identifier: 114331133

GI number: 114331133

Start: 1175675

End: 1176400

Strand: Direct

Name: minC [H]

Synonym: Neut_1135

Alternate gene names: 114331133

Gene position: 1175675-1176400 (Clockwise)

Preceding gene: 114331124

Following gene: 114331134

Centisome position: 44.18

GC content: 47.38

Gene sequence:

>726_bases
ATGAATCAGTCTTCTATCTTAGATTTCAGGAGCGCCACTTCTTTTGTGCCAATCCTGGTTCTCTACAGCAATGACATGGA
AATGATCAGCAAGCGATTGCAGGAGAAAATTGCGAGCGCTCCCGGCTTTTTCAGAAATTCTCCTGTGTTGTTTGATTTAA
GCGAGTTGAATGAAAATGACATGGAAATTGATGTCGCAGCGCTTATATCACGCCTTCGCCAATTGAGTCTGTTTCCTGTC
GGGATCAGGGGTGGAGATCCGCTGCAGGAAAAGCAGGCATTGGCGTTGGCTGTTCCGGTTGACTCTGGCCGTAGCCGTAG
TAACCCTGTTTTGCCTGAAGTACAAAAAAAGGACGATGCCGTTCCTGAATTTCAGGCTGTAATCAGGGATGCAGTTCATG
CTCCAGCGATGATGATTACTCAGCCGGTACGTTCAGGTCAGCGTGTCTACGCTGCCAGTGATCTGGTGATTCTGGCACAA
GTCAGCGCCGGTGCGGAAATTATGGCCGAAGGCAATATCCATATTTACAACACATTAAGAGGGCGTGCTTTAGCTGGTGT
GCAGGGAGATATTGAGGCAAGACTTTTTTGCCTGGATCTGCAGGCGGAGCTGGTATCGATTGCGGGGATTTATAAGACTA
TCGAAGATTTGAAGGAGATTTCCAGGAAGAAGCCGGTACAGGTTTATTTACGGGACCAAGCATTGATCATCCAAGAATTA
AGCTAA

Upstream 100 bases:

>100_bases
AATGCTTTTTATATCCGGCCCCGGGTTATCTTGCATAATTCCATTTTTCACATGTCTTTGCATCATAGCCGGTTTTGTAC
GAGGCTGAGGAATTGCTAAT

Downstream 100 bases:

>100_bases
AAATATTTCTGAGAAGGAGATTCAATTGGCAAGAATTATTGTTGTAACATCTGGGAAGGGAGGGGTTGGCAAAACCACAA
CCAGTGCTGCTATTGCCATG

Product: septum site-determining protein MinC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNQSSILDFRSATSFVPILVLYSNDMEMISKRLQEKIASAPGFFRNSPVLFDLSELNENDMEIDVAALISRLRQLSLFPV
GIRGGDPLQEKQALALAVPVDSGRSRSNPVLPEVQKKDDAVPEFQAVIRDAVHAPAMMITQPVRSGQRVYAASDLVILAQ
VSAGAEIMAEGNIHIYNTLRGRALAGVQGDIEARLFCLDLQAELVSIAGIYKTIEDLKEISRKKPVQVYLRDQALIIQEL
S

Sequences:

>Translated_241_residues
MNQSSILDFRSATSFVPILVLYSNDMEMISKRLQEKIASAPGFFRNSPVLFDLSELNENDMEIDVAALISRLRQLSLFPV
GIRGGDPLQEKQALALAVPVDSGRSRSNPVLPEVQKKDDAVPEFQAVIRDAVHAPAMMITQPVRSGQRVYAASDLVILAQ
VSAGAEIMAEGNIHIYNTLRGRALAGVQGDIEARLFCLDLQAELVSIAGIYKTIEDLKEISRKKPVQVYLRDQALIIQEL
S
>Mature_241_residues
MNQSSILDFRSATSFVPILVLYSNDMEMISKRLQEKIASAPGFFRNSPVLFDLSELNENDMEIDVAALISRLRQLSLFPV
GIRGGDPLQEKQALALAVPVDSGRSRSNPVLPEVQKKDDAVPEFQAVIRDAVHAPAMMITQPVRSGQRVYAASDLVILAQ
VSAGAEIMAEGNIHIYNTLRGRALAGVQGDIEARLFCLDLQAELVSIAGIYKTIEDLKEISRKKPVQVYLRDQALIIQEL
S

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=238, Percent_Identity=32.7731092436975, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 26532; Mature: 26532

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSSILDFRSATSFVPILVLYSNDMEMISKRLQEKIASAPGFFRNSPVLFDLSELNEND
CCCCHHCHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCC
MEIDVAALISRLRQLSLFPVGIRGGDPLQEKQALALAVPVDSGRSRSNPVLPEVQKKDDA
CEEEHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
VPEFQAVIRDAVHAPAMMITQPVRSGQRVYAASDLVILAQVSAGAEIMAEGNIHIYNTLR
CHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCEEEEEEECCCCEEEECCCEEEEECCC
GRALAGVQGDIEARLFCLDLQAELVSIAGIYKTIEDLKEISRKKPVQVYLRDQALIIQEL
CCEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEC
S
C
>Mature Secondary Structure
MNQSSILDFRSATSFVPILVLYSNDMEMISKRLQEKIASAPGFFRNSPVLFDLSELNEND
CCCCHHCHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCC
MEIDVAALISRLRQLSLFPVGIRGGDPLQEKQALALAVPVDSGRSRSNPVLPEVQKKDDA
CEEEHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
VPEFQAVIRDAVHAPAMMITQPVRSGQRVYAASDLVILAQVSAGAEIMAEGNIHIYNTLR
CHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCEEEEEEECCCCEEEECCCEEEEECCC
GRALAGVQGDIEARLFCLDLQAELVSIAGIYKTIEDLKEISRKKPVQVYLRDQALIIQEL
CCEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]