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The map label for this gene is udg [H]

Identifier: 114331091

GI number: 114331091

Start: 1133125

End: 1134447

Strand: Direct

Name: udg [H]

Synonym: Neut_1093

Alternate gene names: 114331091

Gene position: 1133125-1134447 (Clockwise)

Preceding gene: 114331090

Following gene: 114331092

Centisome position: 42.58

GC content: 45.96

Gene sequence:

>1323_bases
ATGAAAATAAGTGTAATTGGAACTGGCTATGTCGGACTGGTAACAGGTACTTGTCTGGCTGAAGTGGGCAACGATGTGTT
ATGCCTGGATGTGGACGTCAATAAGATCAATTTGTTGAAACAAGGTGAGATTCCGATTTATGAACCTGATCTAGAAGACA
TGGTCAGGCGCAATGTATCCGTAGGCCGTTTGCGCTTTACTTTGGATCAGGCAGAATGTACGGATCACGGGTTGGTACAA
TTTATCGCAGTCGGGACCCCGCCAGATGAGGATGGTTCTGCCGATATGCAATACGTTACGACGGCAGCACGGGCAATTGG
CCAGAATATGCAGGATTATAAGCTGATTGTGGATAAATCCACCGTTCCTGTGGGGACTGTAGATAGAGTACGCGGAGTTA
TTTATGAAGAATTGGCAAAACGTGGTGTTGAGATTGATTTCAGTGTTGCATCCAATCCGGAGTTTTTGAAAGAGGGTGCT
GCTGTAGACGATTTTATGCGCCCGGATCGGATCGTTATCGGCGCAGATGATGATAAGGCCATAGAACTTTTACGGACATT
ATATACGCCTTTTAACCGAAATCATGACCGGCTGGTCGTAATGGATGCCAGATCAGCCGAGCTGACCAAATATGCTGCCA
ATGCTATGCTGGCAACACGCATTTCATTTATGAATGAGCTGGCATTACTAGCTGAGAAATTGGGAGCCGATATCGAGCAT
GTTCGTCGGGGGATCGGTTCTGATCCACGTATTGGTTATCATTTTCTGTATGCGGGTTGCGGTTATGGGGGATCTTGTTT
TCCCAAGGATGTTAAGGCATTGCAACGCACTGCAAGAGAAAATGGAACTGGATTAAAAATTCTGGAAGCGGTAGAAGCTG
TGAATGCTCGTCAGAAAGAGGTCTTGCTTGACAAAATTCGGGCAAGATTTGGCTCTGATCTTTCAGGTAAAACATTTGCG
CTGTGGGGACTTGCTTTTAAACCCAATACAGATGATATGCGGGAAGCTCCCAGTAGAATGCTGATTACCGGTTTGTTGGC
GCAGGGTGCTGCTGTTTCTGCTTATGATCCGGTGGCGATGGATGAGACAAAAAGACTTTTCGCGAGTGAACCCGGCCTAA
AACTGGCAAATTCATCTATGTCAGCTTTGGAAGGTGCTGATGCACTCATTGTTGTAACAGAGTGGAAGATGTTCCGTTCT
CCGGATTTCAGTGAAATCCGGCGTAAGCTCAGGAATGCAGTAATTTTTGACGGACGTAATATATACGATCCAGATAGTAT
CCGAACCGAAGGATTTGAGTATTTTTCTATCGGCAGGCCGTGA

Upstream 100 bases:

>100_bases
TTGTTTCTGGGTAGATATTCAAAGCGGAAAATATGTGAGTTAAATTTGTGCCGTGGCTTGGACGTTTACTTTGAGATAAG
ATGAAAATGGGTAGAAAATT

Downstream 100 bases:

>100_bases
ACCAGTGCAGATGTCGCTTGCGTATAAAATTTTACCTGATTAGGGTCTGTTGCCGTTTCAGGCTGTCTTCTTGCTTCATA
AGAACAGACTCGTATTGCCG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKISVIGTGYVGLVTGTCLAEVGNDVLCLDVDVNKINLLKQGEIPIYEPDLEDMVRRNVSVGRLRFTLDQAECTDHGLVQ
FIAVGTPPDEDGSADMQYVTTAARAIGQNMQDYKLIVDKSTVPVGTVDRVRGVIYEELAKRGVEIDFSVASNPEFLKEGA
AVDDFMRPDRIVIGADDDKAIELLRTLYTPFNRNHDRLVVMDARSAELTKYAANAMLATRISFMNELALLAEKLGADIEH
VRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVKALQRTARENGTGLKILEAVEAVNARQKEVLLDKIRARFGSDLSGKTFA
LWGLAFKPNTDDMREAPSRMLITGLLAQGAAVSAYDPVAMDETKRLFASEPGLKLANSSMSALEGADALIVVTEWKMFRS
PDFSEIRRKLRNAVIFDGRNIYDPDSIRTEGFEYFSIGRP

Sequences:

>Translated_440_residues
MKISVIGTGYVGLVTGTCLAEVGNDVLCLDVDVNKINLLKQGEIPIYEPDLEDMVRRNVSVGRLRFTLDQAECTDHGLVQ
FIAVGTPPDEDGSADMQYVTTAARAIGQNMQDYKLIVDKSTVPVGTVDRVRGVIYEELAKRGVEIDFSVASNPEFLKEGA
AVDDFMRPDRIVIGADDDKAIELLRTLYTPFNRNHDRLVVMDARSAELTKYAANAMLATRISFMNELALLAEKLGADIEH
VRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVKALQRTARENGTGLKILEAVEAVNARQKEVLLDKIRARFGSDLSGKTFA
LWGLAFKPNTDDMREAPSRMLITGLLAQGAAVSAYDPVAMDETKRLFASEPGLKLANSSMSALEGADALIVVTEWKMFRS
PDFSEIRRKLRNAVIFDGRNIYDPDSIRTEGFEYFSIGRP
>Mature_440_residues
MKISVIGTGYVGLVTGTCLAEVGNDVLCLDVDVNKINLLKQGEIPIYEPDLEDMVRRNVSVGRLRFTLDQAECTDHGLVQ
FIAVGTPPDEDGSADMQYVTTAARAIGQNMQDYKLIVDKSTVPVGTVDRVRGVIYEELAKRGVEIDFSVASNPEFLKEGA
AVDDFMRPDRIVIGADDDKAIELLRTLYTPFNRNHDRLVVMDARSAELTKYAANAMLATRISFMNELALLAEKLGADIEH
VRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVKALQRTARENGTGLKILEAVEAVNARQKEVLLDKIRARFGSDLSGKTFA
LWGLAFKPNTDDMREAPSRMLITGLLAQGAAVSAYDPVAMDETKRLFASEPGLKLANSSMSALEGADALIVVTEWKMFRS
PDFSEIRRKLRNAVIFDGRNIYDPDSIRTEGFEYFSIGRP

Specific function: Catalyzes The Oxidation Of Udp-Mannac To Udp-N- Acetylmannosaminuronic Acid (Udp-Mannaca). [C]

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=477, Percent_Identity=34.5911949685535, Blast_Score=243, Evalue=4e-64,
Organism=Homo sapiens, GI296040438, Length=379, Percent_Identity=35.3562005277045, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI296040443, Length=325, Percent_Identity=36, Blast_Score=178, Evalue=7e-45,
Organism=Escherichia coli, GI1788340, Length=368, Percent_Identity=29.0760869565217, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI48994968, Length=413, Percent_Identity=28.8135593220339, Blast_Score=148, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17560350, Length=461, Percent_Identity=35.3579175704989, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI17136908, Length=465, Percent_Identity=34.4086021505376, Blast_Score=238, Evalue=8e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48467; Mature: 48467

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISVIGTGYVGLVTGTCLAEVGNDVLCLDVDVNKINLLKQGEIPIYEPDLEDMVRRNVS
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCCCHHHHHHCCCC
VGRLRFTLDQAECTDHGLVQFIAVGTPPDEDGSADMQYVTTAARAIGQNMQDYKLIVDKS
EEEEEEEECHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTVDRVRGVIYEELAKRGVEIDFSVASNPEFLKEGAAVDDFMRPDRIVIGADDDKA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
IELLRTLYTPFNRNHDRLVVMDARSAELTKYAANAMLATRISFMNELALLAEKLGADIEH
HHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVKALQRTARENGTGLKILEAVEAVNARQKE
HHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHH
VLLDKIRARFGSDLSGKTFALWGLAFKPNTDDMREAPSRMLITGLLAQGAAVSAYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCHH
DETKRLFASEPGLKLANSSMSALEGADALIVVTEWKMFRSPDFSEIRRKLRNAVIFDGRN
HHHHHHHHCCCCCEECCCCHHHHCCCCEEEEEEECHHHCCCCHHHHHHHHHHEEEECCCC
IYDPDSIRTEGFEYFSIGRP
CCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MKISVIGTGYVGLVTGTCLAEVGNDVLCLDVDVNKINLLKQGEIPIYEPDLEDMVRRNVS
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCCCHHHHHHCCCC
VGRLRFTLDQAECTDHGLVQFIAVGTPPDEDGSADMQYVTTAARAIGQNMQDYKLIVDKS
EEEEEEEECHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTVDRVRGVIYEELAKRGVEIDFSVASNPEFLKEGAAVDDFMRPDRIVIGADDDKA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
IELLRTLYTPFNRNHDRLVVMDARSAELTKYAANAMLATRISFMNELALLAEKLGADIEH
HHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVKALQRTARENGTGLKILEAVEAVNARQKE
HHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHH
VLLDKIRARFGSDLSGKTFALWGLAFKPNTDDMREAPSRMLITGLLAQGAAVSAYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCHH
DETKRLFASEPGLKLANSSMSALEGADALIVVTEWKMFRSPDFSEIRRKLRNAVIFDGRN
HHHHHHHHCCCCCEECCCCHHHHCCCCEEEEEEECHHHCCCCHHHHHHHHHHEEEECCCC
IYDPDSIRTEGFEYFSIGRP
CCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]