Click here to switch to the map view.

The map label for this gene is aatA [H]

Identifier: 114331081

GI number: 114331081

Start: 1122880

End: 1124073

Strand: Direct

Name: aatA [H]

Synonym: Neut_1083

Alternate gene names: 114331081

Gene position: 1122880-1124073 (Clockwise)

Preceding gene: 114331073

Following gene: 114331083

Centisome position: 42.2

GC content: 47.4

Gene sequence:

>1194_bases
GTGAAACTCTCGCAACGCGTTCAGGCTATCAAACCTTCGCCCACCCTGGCAGTGACTGCCAAAGCAGCCAGGCTCAAGGC
GGAAGGAAAAAATATTATTGGTCTGGGTGCAGGTGAGCCGGATTTCGATACGCCGTTGCATATCAAGGATGCAGCGATTA
CGGCAATCCGGAATGGTTTTACAAAGTATACGGCTGTGGGTGGTACTGCATCTTTAAAGCAGGCGATTATCTCGAAGTTC
AAACGGGAAAATTCCCTGGATTTTACTGCCGGAGAGATCTTGGTCTCCAGCGGAGGAAAACAAAGTTTTTTCAACTTGAT
ACTGGCTACAATTGACCCGGGTGACGAGGTTATCATCCCGGCGCCATACTGGGTTTCCTATCCGGATATGGTCTTGATTG
CACAAGGAAAACCTGTTTTTATTAATACCGGGATCGAAGAAAAATTCAAAATATCAGCCGATCAGCTTGAGAAAGCGATA
ACACCCAGAACCCGCATGTTTATTCTCAACAGCCCAGGCAACCCTTCCGGCAGTGTATACGGTCAGGAAGAATTACAGGC
ATTAGGGGCAGTATTACGTAAACATCCGGAAATTCTGATCGCTACCGATGATATGTATGAACATATCCTCCTGACCAGTG
ATAAGTTCGTCAATATCCTGAACGCTTGCCCTGATCTGAAAGCACGCACCGTTGTCCTCAATGGCGTTTCCAAAGCTTAT
GCCATGACCGGCTGGCGAATTGGCTATTGCGGTGGGCCGGCAGCAATCATAACCGCAATGGAAAATATTCAATCACAAAG
TACATCCAACCCGAACTCTATTGCTCAAATGGCAGCAGAAGCTGCATTAAATGGTGATCAATCCTGCATGATTCCAATGG
TGGAGGCTTTTAAGGAACGCAATCAGTTTCTGACAGATGCGCTGAATTCCATAACGGGTATTCACTGTTTATTATCCGAA
GGGGCATTTTATGCTTTTGCGGATGCAAGGCAGGCAATTAAGCAGTTGCAATCCCAACAAGTGTTGCAGGACAGCAGTGA
CGTTGCTTTTTGCAGTTATTTGCTGGAACAGGCTGAAGTGGCTGTTGTGCCAGGGTCAGCCTTTGGCTGTGAGGGCTATA
TGCGGTTATCGTTTGCGACTTCCATGGAAAATCTCAGGGAGGCTGTCAAGCGTATCGCCAGTTTGCTGAGCTGA

Upstream 100 bases:

>100_bases
TGTCCGGAAAGGTAATAATCACAAGTTTGATCGCTGTACTCGAAATTTAATTATTTTTTGATTCTAACATGCGCAAATCA
CATACATCAGGAGCTGTCTC

Downstream 100 bases:

>100_bases
TCCGCTTCTTGACCCCTATTTTGAGTGATACCTGTTTTGATCAGGCCATTGCAAGATGAGCGGAGAGTGATGCGTAGTAA
CCAGTGCGGATTGCTGTAAA

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKLSQRVQAIKPSPTLAVTAKAARLKAEGKNIIGLGAGEPDFDTPLHIKDAAITAIRNGFTKYTAVGGTASLKQAIISKF
KRENSLDFTAGEILVSSGGKQSFFNLILATIDPGDEVIIPAPYWVSYPDMVLIAQGKPVFINTGIEEKFKISADQLEKAI
TPRTRMFILNSPGNPSGSVYGQEELQALGAVLRKHPEILIATDDMYEHILLTSDKFVNILNACPDLKARTVVLNGVSKAY
AMTGWRIGYCGGPAAIITAMENIQSQSTSNPNSIAQMAAEAALNGDQSCMIPMVEAFKERNQFLTDALNSITGIHCLLSE
GAFYAFADARQAIKQLQSQQVLQDSSDVAFCSYLLEQAEVAVVPGSAFGCEGYMRLSFATSMENLREAVKRIASLLS

Sequences:

>Translated_397_residues
MKLSQRVQAIKPSPTLAVTAKAARLKAEGKNIIGLGAGEPDFDTPLHIKDAAITAIRNGFTKYTAVGGTASLKQAIISKF
KRENSLDFTAGEILVSSGGKQSFFNLILATIDPGDEVIIPAPYWVSYPDMVLIAQGKPVFINTGIEEKFKISADQLEKAI
TPRTRMFILNSPGNPSGSVYGQEELQALGAVLRKHPEILIATDDMYEHILLTSDKFVNILNACPDLKARTVVLNGVSKAY
AMTGWRIGYCGGPAAIITAMENIQSQSTSNPNSIAQMAAEAALNGDQSCMIPMVEAFKERNQFLTDALNSITGIHCLLSE
GAFYAFADARQAIKQLQSQQVLQDSSDVAFCSYLLEQAEVAVVPGSAFGCEGYMRLSFATSMENLREAVKRIASLLS
>Mature_397_residues
MKLSQRVQAIKPSPTLAVTAKAARLKAEGKNIIGLGAGEPDFDTPLHIKDAAITAIRNGFTKYTAVGGTASLKQAIISKF
KRENSLDFTAGEILVSSGGKQSFFNLILATIDPGDEVIIPAPYWVSYPDMVLIAQGKPVFINTGIEEKFKISADQLEKAI
TPRTRMFILNSPGNPSGSVYGQEELQALGAVLRKHPEILIATDDMYEHILLTSDKFVNILNACPDLKARTVVLNGVSKAY
AMTGWRIGYCGGPAAIITAMENIQSQSTSNPNSIAQMAAEAALNGDQSCMIPMVEAFKERNQFLTDALNSITGIHCLLSE
GAFYAFADARQAIKQLQSQQVLQDSSDVAFCSYLLEQAEVAVVPGSAFGCEGYMRLSFATSMENLREAVKRIASLLS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=403, Percent_Identity=25.8064516129032, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI56713254, Length=403, Percent_Identity=25.8064516129032, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI95147551, Length=412, Percent_Identity=22.5728155339806, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI169881279, Length=412, Percent_Identity=22.5728155339806, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI169881281, Length=295, Percent_Identity=21.0169491525424, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4507369, Length=389, Percent_Identity=22.6221079691517, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI19263340, Length=399, Percent_Identity=22.0551378446115, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI215599424, Length=404, Percent_Identity=22.029702970297, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=28.5333333333333, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788722, Length=400, Percent_Identity=28.25, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788627, Length=398, Percent_Identity=28.1407035175879, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=374, Percent_Identity=24.331550802139, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=401, Percent_Identity=25.6857855361596, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=401, Percent_Identity=25.6857855361596, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=25.3968253968254, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=395, Percent_Identity=25.3164556962025, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6323118, Length=351, Percent_Identity=22.7920227920228, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573069, Length=425, Percent_Identity=26.1176470588235, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646114, Length=425, Percent_Identity=26.1176470588235, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573067, Length=425, Percent_Identity=26.1176470588235, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573065, Length=425, Percent_Identity=26.1176470588235, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=23.6979166666667, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42798; Mature: 42798

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSQRVQAIKPSPTLAVTAKAARLKAEGKNIIGLGAGEPDFDTPLHIKDAAITAIRNGF
CCHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHCCC
TKYTAVGGTASLKQAIISKFKRENSLDFTAGEILVSSGGKQSFFNLILATIDPGDEVIIP
HHEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHEEEEEECCCCCEEEC
APYWVSYPDMVLIAQGKPVFINTGIEEKFKISADQLEKAITPRTRMFILNSPGNPSGSVY
CCCEECCCCEEEEECCCCEEEECCCCCCEECCHHHHHHHCCCCEEEEEEECCCCCCCCCC
GQEELQALGAVLRKHPEILIATDDMYEHILLTSDKFVNILNACPDLKARTVVLNGVSKAY
CHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCHHHH
AMTGWRIGYCGGPAAIITAMENIQSQSTSNPNSIAQMAAEAALNGDQSCMIPMVEAFKER
HHCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
NQFLTDALNSITGIHCLLSEGAFYAFADARQAIKQLQSQQVLQDSSDVAFCSYLLEQAEV
HHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCE
AVVPGSAFGCEGYMRLSFATSMENLREAVKRIASLLS
EEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKLSQRVQAIKPSPTLAVTAKAARLKAEGKNIIGLGAGEPDFDTPLHIKDAAITAIRNGF
CCHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHCCC
TKYTAVGGTASLKQAIISKFKRENSLDFTAGEILVSSGGKQSFFNLILATIDPGDEVIIP
HHEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHEEEEEECCCCCEEEC
APYWVSYPDMVLIAQGKPVFINTGIEEKFKISADQLEKAITPRTRMFILNSPGNPSGSVY
CCCEECCCCEEEEECCCCEEEECCCCCCEECCHHHHHHHCCCCEEEEEEECCCCCCCCCC
GQEELQALGAVLRKHPEILIATDDMYEHILLTSDKFVNILNACPDLKARTVVLNGVSKAY
CHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCHHHH
AMTGWRIGYCGGPAAIITAMENIQSQSTSNPNSIAQMAAEAALNGDQSCMIPMVEAFKER
HHCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
NQFLTDALNSITGIHCLLSEGAFYAFADARQAIKQLQSQQVLQDSSDVAFCSYLLEQAEV
HHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCE
AVVPGSAFGCEGYMRLSFATSMENLREAVKRIASLLS
EEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA