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The map label for this gene is nylB' [H]

Identifier: 114331071

GI number: 114331071

Start: 1105879

End: 1107549

Strand: Reverse

Name: nylB' [H]

Synonym: Neut_1073

Alternate gene names: 114331071

Gene position: 1107549-1105879 (Counterclockwise)

Preceding gene: 114331074

Following gene: 114331070

Centisome position: 41.62

GC content: 59.13

Gene sequence:

>1671_bases
ATGAGAACATATCAAACGATTTGGTGCTACGCTGCATTTTCACTGGTGCTGCTGAACGCGCCTCTGGCTGCACGCGCTGC
CGAAACTGCACCCGCAAGTACTCGGCAAATCGCCGCTGACAACGCACTGGCCGGAACTGAATGGGAATTGACTGCGCCCG
CTTACATCAGTTTGGAAAAGCGCCCAGTCTTGAAGTTCACCGACACGCGGTTAAACGCCTCAGTCGGGCTGAACTCTATC
TTCGGCGGTTACGCGCTCAAAGGCAACACCATCAGCCTTCAACCGTTGGGTTCAACGCGCATGGCCGGTCCTGAATCGTT
GATGAATGCGGAAGACCGTTACGGCAAAGCGTTGGGAAGCGTACGCAGCTTTGAACTTTCCGCCGACCGGCAGCAGCTCA
CGCTGCGCGGCGAGCAAACTCTGGTGTTTCGCATGACTTCCACTTCACCACAACCGCAGCAGTTTCTTTCGGCGCGCGAC
AGCGACCCCATCAAAATGGGCTGGATGCAGGGCTTTCCGCCTCCGCCCGACAAGCGGTTGAACTTCGCCGACGGCTCGTT
CTTCCAATTCCCCGCGCTGCGCTGGAGCGTGGTGCATATGCGCGAGTTCATGCCGACCGTCAACGTTTCGCGCGGACTGC
GAGTACTCGCGCCGTTGCCGCGTCGCCTCGATTCTCACATTGATTCGATTCGTTTTCGCCCCCTGAATGGCGCGCCGGAA
ATGACGTGGGAAGAATCGCTGTGGCACAACTACACCGACGGCATTTTGGTGTTGCATCGCGGTCGCATCGTCTATGAAAA
GTACTTTGGCGCGCTTGCGCCCGACAAGCAGCACGCCGCGATGTCGGTGACGAAATCGCTCACCGGCACGCTGGGCGCGG
TCTTGGTCGCCGAAGGCAAGCTGGACGAAAACAAGACGGTGGCCGCTTACATTCCCGAACTGAAAGATTCTGCCTTTGGA
GATGCGACGGTGCGACAGGTGCTGGACATGACGACTGCGCTGCAATTCAGCGAAGAGTACGCCAACCCCAAAGCCGAAAT
CTGGAAGTACTCCGGCGCGGGCAATGTCCTTCCCAAGCCCAAAGATTACCAAGGCCCGGTCGGTTATTACGCCGCGCTGC
AAACGATTCAAAAAGCGGGCGCGCACGGCGAAGCCTTCGGCTACAAAACGCCCAACGCCGACGCTCTGGGCTGGCTCGTC
GCGCGGGCGAGCGGCCAATCGGTGGATGAACTGCTGGCCGAGCGCGTATGGAGCAAAATCGGCATGGAGCAGGACGCCTA
CTATTCGGTAGACGCGCTGGGCGTTCCGTTTGCCGGCGGCGGCTTCAACGCCGGTCTGCGCGACATGGCGCGCTTTGGCG
AGTTGGTTCGCAACAAAGGTCGCTGGAAAGGGCAACAGATTCTGCCCGCTCAAGCGATGGAAGAAATCGCGCGCGGCGAC
CATCCCGAACTCAAAGGCTGGTCGTATCGGGATATGTGGTGGCACACCGGAAACGCTAATGGCGCTTTCGCAGCGCGCGG
CGTGCATGGTCAAACCATTTACATCGACCCTAAAGCCGAAATGGTGATTGTGCGTTTCGCTTCGCATCCCATCGCCGCCA
ACAGCGCCAACGACGCGACTTCGCTGCCCGCCTACGAAGCCGTCGCGCGCCATTTGATGAAAGGAAAATAA

Upstream 100 bases:

>100_bases
GTCGCGTTTCTTTAATAGCTGTCATAAACTACCTCCCTTTGCTGTTTTACAGGCTTAACAAAGTGTCCGGAAGTATTAGA
CCAGAACAATATCAATTTAA

Downstream 100 bases:

>100_bases
CCTTATGCAACCGACACCACTGTTCGATTTGAGCGGCAAAGTCGCCATCGTGACCGGCGGCGGCAACGGCATCGGCAAAG
CCTGCGCGCGGATGCTGGCC

Product: 6-aminohexanoate-dimer hydrolase

Products: NA

Alternate protein names: Nylon oligomers-degrading enzyme EII' [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MRTYQTIWCYAAFSLVLLNAPLAARAAETAPASTRQIAADNALAGTEWELTAPAYISLEKRPVLKFTDTRLNASVGLNSI
FGGYALKGNTISLQPLGSTRMAGPESLMNAEDRYGKALGSVRSFELSADRQQLTLRGEQTLVFRMTSTSPQPQQFLSARD
SDPIKMGWMQGFPPPPDKRLNFADGSFFQFPALRWSVVHMREFMPTVNVSRGLRVLAPLPRRLDSHIDSIRFRPLNGAPE
MTWEESLWHNYTDGILVLHRGRIVYEKYFGALAPDKQHAAMSVTKSLTGTLGAVLVAEGKLDENKTVAAYIPELKDSAFG
DATVRQVLDMTTALQFSEEYANPKAEIWKYSGAGNVLPKPKDYQGPVGYYAALQTIQKAGAHGEAFGYKTPNADALGWLV
ARASGQSVDELLAERVWSKIGMEQDAYYSVDALGVPFAGGGFNAGLRDMARFGELVRNKGRWKGQQILPAQAMEEIARGD
HPELKGWSYRDMWWHTGNANGAFAARGVHGQTIYIDPKAEMVIVRFASHPIAANSANDATSLPAYEAVARHLMKGK

Sequences:

>Translated_556_residues
MRTYQTIWCYAAFSLVLLNAPLAARAAETAPASTRQIAADNALAGTEWELTAPAYISLEKRPVLKFTDTRLNASVGLNSI
FGGYALKGNTISLQPLGSTRMAGPESLMNAEDRYGKALGSVRSFELSADRQQLTLRGEQTLVFRMTSTSPQPQQFLSARD
SDPIKMGWMQGFPPPPDKRLNFADGSFFQFPALRWSVVHMREFMPTVNVSRGLRVLAPLPRRLDSHIDSIRFRPLNGAPE
MTWEESLWHNYTDGILVLHRGRIVYEKYFGALAPDKQHAAMSVTKSLTGTLGAVLVAEGKLDENKTVAAYIPELKDSAFG
DATVRQVLDMTTALQFSEEYANPKAEIWKYSGAGNVLPKPKDYQGPVGYYAALQTIQKAGAHGEAFGYKTPNADALGWLV
ARASGQSVDELLAERVWSKIGMEQDAYYSVDALGVPFAGGGFNAGLRDMARFGELVRNKGRWKGQQILPAQAMEEIARGD
HPELKGWSYRDMWWHTGNANGAFAARGVHGQTIYIDPKAEMVIVRFASHPIAANSANDATSLPAYEAVARHLMKGK
>Mature_556_residues
MRTYQTIWCYAAFSLVLLNAPLAARAAETAPASTRQIAADNALAGTEWELTAPAYISLEKRPVLKFTDTRLNASVGLNSI
FGGYALKGNTISLQPLGSTRMAGPESLMNAEDRYGKALGSVRSFELSADRQQLTLRGEQTLVFRMTSTSPQPQQFLSARD
SDPIKMGWMQGFPPPPDKRLNFADGSFFQFPALRWSVVHMREFMPTVNVSRGLRVLAPLPRRLDSHIDSIRFRPLNGAPE
MTWEESLWHNYTDGILVLHRGRIVYEKYFGALAPDKQHAAMSVTKSLTGTLGAVLVAEGKLDENKTVAAYIPELKDSAFG
DATVRQVLDMTTALQFSEEYANPKAEIWKYSGAGNVLPKPKDYQGPVGYYAALQTIQKAGAHGEAFGYKTPNADALGWLV
ARASGQSVDELLAERVWSKIGMEQDAYYSVDALGVPFAGGGFNAGLRDMARFGELVRNKGRWKGQQILPAQAMEEIARGD
HPELKGWSYRDMWWHTGNANGAFAARGVHGQTIYIDPKAEMVIVRFASHPIAANSANDATSLPAYEAVARHLMKGK

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.1.46 [H]

Molecular weight: Translated: 61156; Mature: 61156

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTYQTIWCYAAFSLVLLNAPLAARAAETAPASTRQIAADNALAGTEWELTAPAYISLEK
CCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHCCCCCCCCCEEECCCEEEEECC
RPVLKFTDTRLNASVGLNSIFGGYALKGNTISLQPLGSTRMAGPESLMNAEDRYGKALGS
CCCEEEECCCCCHHCCCHHHCCCEEEECCEEEEEECCCCCCCCHHHHHCCHHHHHHHHCC
VRSFELSADRQQLTLRGEQTLVFRMTSTSPQPQQFLSARDSDPIKMGWMQGFPPPPDKRL
CCEEEECCCCCEEEEECCEEEEEEEECCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCE
NFADGSFFQFPALRWSVVHMREFMPTVNVSRGLRVLAPLPRRLDSHIDSIRFRPLNGAPE
ECCCCCEEECCCHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHCEEEEECCCCCC
MTWEESLWHNYTDGILVLHRGRIVYEKYFGALAPDKQHAAMSVTKSLTGTLGAVLVAEGK
CCHHHHHHCCCCCCEEEEECCCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCC
LDENKTVAAYIPELKDSAFGDATVRQVLDMTTALQFSEEYANPKAEIWKYSGAGNVLPKP
CCCCCEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCC
KDYQGPVGYYAALQTIQKAGAHGEAFGYKTPNADALGWLVARASGQSVDELLAERVWSKI
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHEECCCCCCHHHHHHHHHHHHH
GMEQDAYYSVDALGVPFAGGGFNAGLRDMARFGELVRNKGRWKGQQILPAQAMEEIARGD
CCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHCCC
HPELKGWSYRDMWWHTGNANGAFAARGVHGQTIYIDPKAEMVIVRFASHPIAANSANDAT
CCCCCCCCCCCCEEECCCCCCCEEECCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCC
SLPAYEAVARHLMKGK
CCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRTYQTIWCYAAFSLVLLNAPLAARAAETAPASTRQIAADNALAGTEWELTAPAYISLEK
CCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHCCCCCCCCCEEECCCEEEEECC
RPVLKFTDTRLNASVGLNSIFGGYALKGNTISLQPLGSTRMAGPESLMNAEDRYGKALGS
CCCEEEECCCCCHHCCCHHHCCCEEEECCEEEEEECCCCCCCCHHHHHCCHHHHHHHHCC
VRSFELSADRQQLTLRGEQTLVFRMTSTSPQPQQFLSARDSDPIKMGWMQGFPPPPDKRL
CCEEEECCCCCEEEEECCEEEEEEEECCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCE
NFADGSFFQFPALRWSVVHMREFMPTVNVSRGLRVLAPLPRRLDSHIDSIRFRPLNGAPE
ECCCCCEEECCCHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHCEEEEECCCCCC
MTWEESLWHNYTDGILVLHRGRIVYEKYFGALAPDKQHAAMSVTKSLTGTLGAVLVAEGK
CCHHHHHHCCCCCCEEEEECCCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCC
LDENKTVAAYIPELKDSAFGDATVRQVLDMTTALQFSEEYANPKAEIWKYSGAGNVLPKP
CCCCCEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCC
KDYQGPVGYYAALQTIQKAGAHGEAFGYKTPNADALGWLVARASGQSVDELLAERVWSKI
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHEECCCCCCHHHHHHHHHHHHH
GMEQDAYYSVDALGVPFAGGGFNAGLRDMARFGELVRNKGRWKGQQILPAQAMEEIARGD
CCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHCCC
HPELKGWSYRDMWWHTGNANGAFAARGVHGQTIYIDPKAEMVIVRFASHPIAANSANDAT
CCCCCCCCCCCCEEECCCCCCCEEECCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCC
SLPAYEAVARHLMKGK
CCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6646204; 6389532; 1879421 [H]