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The map label for this gene is argA [H]

Identifier: 114331047

GI number: 114331047

Start: 1084945

End: 1086279

Strand: Reverse

Name: argA [H]

Synonym: Neut_1048

Alternate gene names: 114331047

Gene position: 1086279-1084945 (Counterclockwise)

Preceding gene: 114331048

Following gene: 114331040

Centisome position: 40.82

GC content: 49.36

Gene sequence:

>1335_bases
ATGCAATCGGACATCGAATTTGTTACCTGGTTTCGCTCCGTTACTCCGCATATCCACACCAGTCGTGGAAAAATCTTCGT
TATCGCTTTTGGTGGTGAAGTCGTTGTGAATGGAAAATTTGTCGAGCTGGTGCAGGATTTTAACCTGCTTGCCAGTCTCG
GCATCCAGCTCGTATTGGTGCATGGCGCGCGACCGCAAATTGAATCCAGATTACAGGCTGATCAGCAGGAAATAAGTTAC
GTACAAGGTATGCGTGTTACCGATGTCACTACACTGCAATATGTGAAAGAAGCGGTCGGTAAAGTCCGGGTTGAAATCGA
GGCTCTGCTGTCGATGGGGCTGCCTAATTCGCCTATGGCCAATGCCGCCATACGGGTAGCCAGCGGAAATTTCGTAACTG
CTCGCCCGATCGGTGTTTTGGAAGGGGTGGACCTGCAATACACTGGAGAAGTACGCCGTATCAATGCCGCAGCCATCCTC
GATCAACTTAAACAAGGGGTTGTCGTGCTGCTCTCACCTCTGGGCTATTCACCAACGGGAGAAATTTTTAATCTGACAGT
AGAAAATACTGCCGCTGAAGTCGCCATTGCCCTGAGAGCCGACAAGCTGATTTTTCTGGTAGATACGCCCGGCATCCAGC
AACAAACAGAATCAGGTAATACGTTATTGCAAGAACTTACTGTCAGGCAGGGTAAAGCGCTACTTGCGGCAATGGATACT
GCAGCAGATCAACCAAATGAAGATATCCGCCTCTATCTGCCATGGGCATTGCATGCCTGCGAACAGGGAGTGGAACGTGT
TCATCTTATCAGTCGTCATGCTGATGGCGCTCTGTTACTTGAGTTGTTCACGCACGGTGGCATTGGCAGCATGATCACAC
GTGACCCACTACAAATTATCCGTCAGGCTGATATCAAGGACATTGGTGCCATACTGCAGTTAATCGAACCACTGGAAAAT
ACGGGTATTCTGGTGAGGCGTGGCCGGGAATTACTGGAAATGGAAATTGAACGTTTTACAGTGATTGAACATGACAACGT
GATCATTGCCTGTGCAGCACTCTACCCTTTCCCGGATGACAAAGCATGCGAACTGGCCTGCGTCGCAGTACATCCTGCAT
ATCGCAAAGCGGGAATGGGTCGGATACTGATTGATCACCTGGAAGAACAAGCCAGAAAACAAGGCTACCGCCATATATTT
GTCCTCACTACCCGTACCGCTCACTGGTTTGTAGAGCGTGGTTTCTCGGAAACCACCCCTGACCAGCTTCCACAGTCAAA
GCAGCATCTCTACAACTATCAGCGCCGCTCAAAGGTTTTCGTCAAATCAATCTGA

Upstream 100 bases:

>100_bases
GCACTCGTATTCTGCGCACCGAAACCGCTGCATTGGCAGCCATTGCCGCCGCCCAGGTGCTCTGGGGTGATTATTAATAG
TGCTTCTACCTTGATCAGCC

Downstream 100 bases:

>100_bases
AACCTGATCGCCCACTCTGCCTATTGTTCTTTATCGCTGAGGAACACAAATCTGGAATCATGCAAAATCAGCTTTGAGGA
TTATCTTCTTGAGGCTCATC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MQSDIEFVTWFRSVTPHIHTSRGKIFVIAFGGEVVVNGKFVELVQDFNLLASLGIQLVLVHGARPQIESRLQADQQEISY
VQGMRVTDVTTLQYVKEAVGKVRVEIEALLSMGLPNSPMANAAIRVASGNFVTARPIGVLEGVDLQYTGEVRRINAAAIL
DQLKQGVVVLLSPLGYSPTGEIFNLTVENTAAEVAIALRADKLIFLVDTPGIQQQTESGNTLLQELTVRQGKALLAAMDT
AADQPNEDIRLYLPWALHACEQGVERVHLISRHADGALLLELFTHGGIGSMITRDPLQIIRQADIKDIGAILQLIEPLEN
TGILVRRGRELLEMEIERFTVIEHDNVIIACAALYPFPDDKACELACVAVHPAYRKAGMGRILIDHLEEQARKQGYRHIF
VLTTRTAHWFVERGFSETTPDQLPQSKQHLYNYQRRSKVFVKSI

Sequences:

>Translated_444_residues
MQSDIEFVTWFRSVTPHIHTSRGKIFVIAFGGEVVVNGKFVELVQDFNLLASLGIQLVLVHGARPQIESRLQADQQEISY
VQGMRVTDVTTLQYVKEAVGKVRVEIEALLSMGLPNSPMANAAIRVASGNFVTARPIGVLEGVDLQYTGEVRRINAAAIL
DQLKQGVVVLLSPLGYSPTGEIFNLTVENTAAEVAIALRADKLIFLVDTPGIQQQTESGNTLLQELTVRQGKALLAAMDT
AADQPNEDIRLYLPWALHACEQGVERVHLISRHADGALLLELFTHGGIGSMITRDPLQIIRQADIKDIGAILQLIEPLEN
TGILVRRGRELLEMEIERFTVIEHDNVIIACAALYPFPDDKACELACVAVHPAYRKAGMGRILIDHLEEQARKQGYRHIF
VLTTRTAHWFVERGFSETTPDQLPQSKQHLYNYQRRSKVFVKSI
>Mature_444_residues
MQSDIEFVTWFRSVTPHIHTSRGKIFVIAFGGEVVVNGKFVELVQDFNLLASLGIQLVLVHGARPQIESRLQADQQEISY
VQGMRVTDVTTLQYVKEAVGKVRVEIEALLSMGLPNSPMANAAIRVASGNFVTARPIGVLEGVDLQYTGEVRRINAAAIL
DQLKQGVVVLLSPLGYSPTGEIFNLTVENTAAEVAIALRADKLIFLVDTPGIQQQTESGNTLLQELTVRQGKALLAAMDT
AADQPNEDIRLYLPWALHACEQGVERVHLISRHADGALLLELFTHGGIGSMITRDPLQIIRQADIKDIGAILQLIEPLEN
TGILVRRGRELLEMEIERFTVIEHDNVIIACAALYPFPDDKACELACVAVHPAYRKAGMGRILIDHLEEQARKQGYRHIF
VLTTRTAHWFVERGFSETTPDQLPQSKQHLYNYQRRSKVFVKSI

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=439, Percent_Identity=48.74715261959, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6320913, Length=312, Percent_Identity=21.7948717948718, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49337; Mature: 49337

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSDIEFVTWFRSVTPHIHTSRGKIFVIAFGGEVVVNGKFVELVQDFNLLASLGIQLVLV
CCCCHHHHHHHHHCCCCEECCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHCCEEEEEE
HGARPQIESRLQADQQEISYVQGMRVTDVTTLQYVKEAVGKVRVEIEALLSMGLPNSPMA
ECCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NAAIRVASGNFVTARPIGVLEGVDLQYTGEVRRINAAAILDQLKQGVVVLLSPLGYSPTG
CCEEEEECCCEEEECCCCCCCCCCEEECCCCEEHHHHHHHHHHHCCEEEEEECCCCCCCC
EIFNLTVENTAAEVAIALRADKLIFLVDTPGIQQQTESGNTLLQELTVRQGKALLAAMDT
CEEEEEEECCCEEEEEEEEECEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
AADQPNEDIRLYLPWALHACEQGVERVHLISRHADGALLLELFTHGGIGSMITRDPLQII
HCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHCHHHHH
RQADIKDIGAILQLIEPLENTGILVRRGRELLEMEIERFTVIEHDNVIIACAALYPFPDD
HHCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHEEEEECCCEEEEEEEECCCCCC
KACELACVAVHPAYRKAGMGRILIDHLEEQARKQGYRHIFVLTTRTAHWFVERGFSETTP
CCCEEEEEEECHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHCCCCCCCH
DQLPQSKQHLYNYQRRSKVFVKSI
HHCCCHHHHHHHHHHHCEEEEECC
>Mature Secondary Structure
MQSDIEFVTWFRSVTPHIHTSRGKIFVIAFGGEVVVNGKFVELVQDFNLLASLGIQLVLV
CCCCHHHHHHHHHCCCCEECCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHCCEEEEEE
HGARPQIESRLQADQQEISYVQGMRVTDVTTLQYVKEAVGKVRVEIEALLSMGLPNSPMA
ECCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NAAIRVASGNFVTARPIGVLEGVDLQYTGEVRRINAAAILDQLKQGVVVLLSPLGYSPTG
CCEEEEECCCEEEECCCCCCCCCCEEECCCCEEHHHHHHHHHHHCCEEEEEECCCCCCCC
EIFNLTVENTAAEVAIALRADKLIFLVDTPGIQQQTESGNTLLQELTVRQGKALLAAMDT
CEEEEEEECCCEEEEEEEEECEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
AADQPNEDIRLYLPWALHACEQGVERVHLISRHADGALLLELFTHGGIGSMITRDPLQII
HCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHCHHHHH
RQADIKDIGAILQLIEPLENTGILVRRGRELLEMEIERFTVIEHDNVIIACAALYPFPDD
HHCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHEEEEECCCEEEEEEEECCCCCC
KACELACVAVHPAYRKAGMGRILIDHLEEQARKQGYRHIFVLTTRTAHWFVERGFSETTP
CCCEEEEEEECHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHCCCCCCCH
DQLPQSKQHLYNYQRRSKVFVKSI
HHCCCHHHHHHHHHHHCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]