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The map label for this gene is pilC [H]

Identifier: 114331042

GI number: 114331042

Start: 1081099

End: 1082319

Strand: Direct

Name: pilC [H]

Synonym: Neut_1043

Alternate gene names: 114331042

Gene position: 1081099-1082319 (Clockwise)

Preceding gene: 114331041

Following gene: 114331043

Centisome position: 40.63

GC content: 46.36

Gene sequence:

>1221_bases
ATGGTAACGATCGCGACATCAGAAAAGAAAGTCAAAGAATTCAATTTTATATGGGAAGGAAAAGATAAAACCGGAAGGGC
GATTAAAGGCGAAATGCGTGCGGCTGGCACTGTTGTAGTGACTTCTACACTACGCAAACAGGGTATCAGAGTAACAAAAA
TCACCAAGGCCAGGGCGGGTGGAAAAATTACCGATAAGGATATTACGTTGTTTACACGCCAGCTTGCAACGATGATGAAA
TCGGGAGTGCCTTTGTTGCAAGCCTTTGATATTGTAGGCAAGGGACACAGTAATCGTGCAGTCGGGAAACTACTGATGGA
TATCAAATCAGAAGTGGAAACAGGTAGCAGTCTGGCTAATGCATTCAAAAAACATCCACTTTATTTTGACTCCCTGTTTT
GTAACCTGGTGGCAGCGGGGGAAGCTGCCGGTATCCTGGATAACCTGCTTGACAGGTTGGCTACCTATAAGGAAAAGATT
CAGGCGATCAAGGGGAAAATAAAATCGGCATTGTTTTATCCTGTTTCAATCATTGTGGTTGCTTTCATCATTACCGCAGT
AATCATGATATTCGTAATCCCGGCTTTCAAGGAGCTTTTCCAGGGATTTGGTGCTGATCTACCCGCCCCAACCCTGATGG
TCATGACTATTTCTGACTTTTTTGTAGCATACTGGTGGGCAATTTTTGGAGGAATCGGTGGGGGGCTTTATGTATTTTTT
TATGCCTGGAAGCGTTCTGCCGCAATGCAGCATGTCATGGATCGATTGGCTCTGAGGTTACCAATTTTTGGAGAGGTGAT
CCGTAAAGCTACGATCGCCCGTTGGTCGCGGACACTTTCAACTATGTTTGCTGCCGGTGTTCCTTTGGTTGAGGCACTTA
ATTCTGTTGCCGGCGCAGCCGGAAACCAAGTGTATTATGAGGCAACAAAAAATATCCAGAACGAAGTCAGTACCGGCAGC
AGTCTGGTGGATGCGATGATGGCAACCAATGTTTTTCCTTCAATGGTGCTGCAGATGGTTTCCATAGGCGAGGAATCAGG
TTCGCTTGATGCAATGCTCAGCAAAATTGCAGATTTCTTTGAGGCAGAAGTGGATGATGCGGTGGAGGCACTTTCCAGTC
TGATGGAGCCGCTCATCATGGTGGTGCTAGGGACGCTCATTGGCGGAATGGTGGTCGCCATGTATCTGCCTATTTTTAAA
ATGGGGCAGGTGGTCGGATAA

Upstream 100 bases:

>100_bases
GAGCCTGTCTGGCAGAGATAGAAAAAATACCAGTTAAATAATCCTGAACTTTCTGCCGTAGTAACTATGATCCAGATCAG
CAAGATAAAAGGAAATTGGC

Downstream 100 bases:

>100_bases
CCAGATAGTGCCATTTTCACGACTGAATCAGGACAGGCAGTGCATGAATATTTTTAATACCCTGCAAGCTTCACCAGCTT
TTTTTATTTCATTTATCTCG

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MVTIATSEKKVKEFNFIWEGKDKTGRAIKGEMRAAGTVVVTSTLRKQGIRVTKITKARAGGKITDKDITLFTRQLATMMK
SGVPLLQAFDIVGKGHSNRAVGKLLMDIKSEVETGSSLANAFKKHPLYFDSLFCNLVAAGEAAGILDNLLDRLATYKEKI
QAIKGKIKSALFYPVSIIVVAFIITAVIMIFVIPAFKELFQGFGADLPAPTLMVMTISDFFVAYWWAIFGGIGGGLYVFF
YAWKRSAAMQHVMDRLALRLPIFGEVIRKATIARWSRTLSTMFAAGVPLVEALNSVAGAAGNQVYYEATKNIQNEVSTGS
SLVDAMMATNVFPSMVLQMVSIGEESGSLDAMLSKIADFFEAEVDDAVEALSSLMEPLIMVVLGTLIGGMVVAMYLPIFK
MGQVVG

Sequences:

>Translated_406_residues
MVTIATSEKKVKEFNFIWEGKDKTGRAIKGEMRAAGTVVVTSTLRKQGIRVTKITKARAGGKITDKDITLFTRQLATMMK
SGVPLLQAFDIVGKGHSNRAVGKLLMDIKSEVETGSSLANAFKKHPLYFDSLFCNLVAAGEAAGILDNLLDRLATYKEKI
QAIKGKIKSALFYPVSIIVVAFIITAVIMIFVIPAFKELFQGFGADLPAPTLMVMTISDFFVAYWWAIFGGIGGGLYVFF
YAWKRSAAMQHVMDRLALRLPIFGEVIRKATIARWSRTLSTMFAAGVPLVEALNSVAGAAGNQVYYEATKNIQNEVSTGS
SLVDAMMATNVFPSMVLQMVSIGEESGSLDAMLSKIADFFEAEVDDAVEALSSLMEPLIMVVLGTLIGGMVVAMYLPIFK
MGQVVG
>Mature_406_residues
MVTIATSEKKVKEFNFIWEGKDKTGRAIKGEMRAAGTVVVTSTLRKQGIRVTKITKARAGGKITDKDITLFTRQLATMMK
SGVPLLQAFDIVGKGHSNRAVGKLLMDIKSEVETGSSLANAFKKHPLYFDSLFCNLVAAGEAAGILDNLLDRLATYKEKI
QAIKGKIKSALFYPVSIIVVAFIITAVIMIFVIPAFKELFQGFGADLPAPTLMVMTISDFFVAYWWAIFGGIGGGLYVFF
YAWKRSAAMQHVMDRLALRLPIFGEVIRKATIARWSRTLSTMFAAGVPLVEALNSVAGAAGNQVYYEATKNIQNEVSTGS
SLVDAMMATNVFPSMVLQMVSIGEESGSLDAMLSKIADFFEAEVDDAVEALSSLMEPLIMVVLGTLIGGMVVAMYLPIFK
MGQVVG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=399, Percent_Identity=27.3182957393484, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1786295, Length=395, Percent_Identity=28.6075949367089, Blast_Score=161, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44056; Mature: 44056

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIATSEKKVKEFNFIWEGKDKTGRAIKGEMRAAGTVVVTSTLRKQGIRVTKITKARAG
CEEECCCHHHHHHHCCEECCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEEHHHCCC
GKITDKDITLFTRQLATMMKSGVPLLQAFDIVGKGHSNRAVGKLLMDIKSEVETGSSLAN
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHH
AFKKHPLYFDSLFCNLVAAGEAAGILDNLLDRLATYKEKIQAIKGKIKSALFYPVSIIVV
HHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFIITAVIMIFVIPAFKELFQGFGADLPAPTLMVMTISDFFVAYWWAIFGGIGGGLYVFF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YAWKRSAAMQHVMDRLALRLPIFGEVIRKATIARWSRTLSTMFAAGVPLVEALNSVAGAA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GNQVYYEATKNIQNEVSTGSSLVDAMMATNVFPSMVLQMVSIGEESGSLDAMLSKIADFF
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EAEVDDAVEALSSLMEPLIMVVLGTLIGGMVVAMYLPIFKMGQVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTIATSEKKVKEFNFIWEGKDKTGRAIKGEMRAAGTVVVTSTLRKQGIRVTKITKARAG
CEEECCCHHHHHHHCCEECCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEEHHHCCC
GKITDKDITLFTRQLATMMKSGVPLLQAFDIVGKGHSNRAVGKLLMDIKSEVETGSSLAN
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHH
AFKKHPLYFDSLFCNLVAAGEAAGILDNLLDRLATYKEKIQAIKGKIKSALFYPVSIIVV
HHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFIITAVIMIFVIPAFKELFQGFGADLPAPTLMVMTISDFFVAYWWAIFGGIGGGLYVFF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YAWKRSAAMQHVMDRLALRLPIFGEVIRKATIARWSRTLSTMFAAGVPLVEALNSVAGAA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GNQVYYEATKNIQNEVSTGSSLVDAMMATNVFPSMVLQMVSIGEESGSLDAMLSKIADFF
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EAEVDDAVEALSSLMEPLIMVVLGTLIGGMVVAMYLPIFKMGQVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]