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The map label for this gene is glmM

Identifier: 114331002

GI number: 114331002

Start: 1030177

End: 1031553

Strand: Direct

Name: glmM

Synonym: Neut_1000

Alternate gene names: 114331002

Gene position: 1030177-1031553 (Clockwise)

Preceding gene: 114331001

Following gene: 114331003

Centisome position: 38.71

GC content: 45.97

Gene sequence:

>1377_bases
ATGAAGAAAAAATATTTTGGTACAGATGGCATTCGTGGAAAGGTAGGGGAATTTCCGATCACGCCCGAATTCTTCCTGCG
TCTGGGGTATGCTGTTGGCAAAGTATTGCTGGCGTCCGATTGGAAACTGGCTGCAGATAAACGACCAACCATCCTGATTG
GAAAAGATACACGCATATCCGGATACATGCTGGAATCTGCGCTGGAAGCCGGTTTCTCAGCGGCAGGGGTAGATGTTCTG
CTATCCGGGCCATTACCAACCCCTGCTGTGGCCTACCTTGTGCGAGCGCTGCGCATTCAGGCTGGAGCAGTTATTTCTGC
CTCACATAATCCGTTTTATGATAACGGCATTAAATTTTTCTCTTCTGAAGGCTCAAAACTACCTGATAGTATGGAACTTC
AAATCGAAGCTGAACTGGATTTTCCTATAGAAACAGCACCTTCTATCAAATTAGGTAGAGTACAACGTCTCAAGGATGAA
GAAGGCCGATATATCGAATTTTGTAAAAGTACTTTTCCTAATCAGCTTGATTTACGAGGCTGGAAAATCGTGGTTGATTG
TGCCAATGGTGCAGATTACCAGGTCGCCGGGCATGTGATGCATGAACTGGGCGCTGATGTTGTAACTATTCATGCAAATC
CGGACGGATTCAACATTAATCATGAATGTGGTGCAACCCATATCATGACGCTGCAAGGTGCAGTTTTGCAACACGGTGCA
GATTTTGGTATTGCTGTAGATGGCGATGGCGACCGGGTGCTGATGGTGAGTGGAGAAGGGGTAGTATACGATGGTGACAG
TCTGGCCTACATTATCGCTAAACATCGACAACAGCGTGGTGTACTACAAGGTGGAGTAGTTGGGACACTCATGACCAATC
TGGCTGTTGAGCAAGCTTTTGAGCGGATTGGGATTCCATTTGCCCGGGCAAATGTCGGAGATCGTTATGTGTCTGAATTG
CTGCAACAAAATGACTGGTACTTGGGTGCCGAGAATTCCGGCCATATTATTTGCCGTGATAAACATACGACAGGTGACGG
AATTATTTCAGCCCTCCAGGTTTTGTACGCATTACGTGACACGGGTTTGATGTTTGCCGACTTGATGCATGATGTTACTT
TCTTTCCCCAACGGTTAATCAATGTAAAGATTTCCAGAGATTTTGATTTTCAGAACGATCAAGCAGTAGAGATATGCAAA
AATGAGGCGGAACAGGCATTGGGAAATGATGGGCGTATTTTGCTGCGTGCTTCTGGAACTGAACCGTTAATCAGGGTGAT
GGTGGAAGGAAAAGACCCTCAACAGATTGAATACTGGGCTGAGAAAATTGCTGGAACAATTCAGCAACAGGCTGTTGCTT
CAACTGTTGGGCACTGA

Upstream 100 bases:

>100_bases
GTTGATCTATCAGACGCTCGCGTCTGTGGGATGTTGATTGCGATATTGTGAATCCGGTTACATGCTTTGATTTGGAATTC
AACAGGGAAGCGACACTGAT

Downstream 100 bases:

>100_bases
GCTTATCATCACAAGGCTGTAATATATCTCGTTTATCTTTGGTGAATACTTGAAGTTAGAGTTGTAGGGTATACAGGTCA
GATATCTTTTCTTTAATTCT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKKKYFGTDGIRGKVGEFPITPEFFLRLGYAVGKVLLASDWKLAADKRPTILIGKDTRISGYMLESALEAGFSAAGVDVL
LSGPLPTPAVAYLVRALRIQAGAVISASHNPFYDNGIKFFSSEGSKLPDSMELQIEAELDFPIETAPSIKLGRVQRLKDE
EGRYIEFCKSTFPNQLDLRGWKIVVDCANGADYQVAGHVMHELGADVVTIHANPDGFNINHECGATHIMTLQGAVLQHGA
DFGIAVDGDGDRVLMVSGEGVVYDGDSLAYIIAKHRQQRGVLQGGVVGTLMTNLAVEQAFERIGIPFARANVGDRYVSEL
LQQNDWYLGAENSGHIICRDKHTTGDGIISALQVLYALRDTGLMFADLMHDVTFFPQRLINVKISRDFDFQNDQAVEICK
NEAEQALGNDGRILLRASGTEPLIRVMVEGKDPQQIEYWAEKIAGTIQQQAVASTVGH

Sequences:

>Translated_458_residues
MKKKYFGTDGIRGKVGEFPITPEFFLRLGYAVGKVLLASDWKLAADKRPTILIGKDTRISGYMLESALEAGFSAAGVDVL
LSGPLPTPAVAYLVRALRIQAGAVISASHNPFYDNGIKFFSSEGSKLPDSMELQIEAELDFPIETAPSIKLGRVQRLKDE
EGRYIEFCKSTFPNQLDLRGWKIVVDCANGADYQVAGHVMHELGADVVTIHANPDGFNINHECGATHIMTLQGAVLQHGA
DFGIAVDGDGDRVLMVSGEGVVYDGDSLAYIIAKHRQQRGVLQGGVVGTLMTNLAVEQAFERIGIPFARANVGDRYVSEL
LQQNDWYLGAENSGHIICRDKHTTGDGIISALQVLYALRDTGLMFADLMHDVTFFPQRLINVKISRDFDFQNDQAVEICK
NEAEQALGNDGRILLRASGTEPLIRVMVEGKDPQQIEYWAEKIAGTIQQQAVASTVGH
>Mature_458_residues
MKKKYFGTDGIRGKVGEFPITPEFFLRLGYAVGKVLLASDWKLAADKRPTILIGKDTRISGYMLESALEAGFSAAGVDVL
LSGPLPTPAVAYLVRALRIQAGAVISASHNPFYDNGIKFFSSEGSKLPDSMELQIEAELDFPIETAPSIKLGRVQRLKDE
EGRYIEFCKSTFPNQLDLRGWKIVVDCANGADYQVAGHVMHELGADVVTIHANPDGFNINHECGATHIMTLQGAVLQHGA
DFGIAVDGDGDRVLMVSGEGVVYDGDSLAYIIAKHRQQRGVLQGGVVGTLMTNLAVEQAFERIGIPFARANVGDRYVSEL
LQQNDWYLGAENSGHIICRDKHTTGDGIISALQVLYALRDTGLMFADLMHDVTFFPQRLINVKISRDFDFQNDQAVEICK
NEAEQALGNDGRILLRASGTEPLIRVMVEGKDPQQIEYWAEKIAGTIQQQAVASTVGH

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=447, Percent_Identity=57.0469798657718, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1788361, Length=458, Percent_Identity=27.9475982532751, Blast_Score=113, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323752, Length=369, Percent_Identity=25.2032520325203, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_NITEC (Q0AHC3)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747224.1
- ProteinModelPortal:   Q0AHC3
- SMR:   Q0AHC3
- STRING:   Q0AHC3
- GeneID:   4274152
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1000
- NMPDR:   fig|335283.3.peg.2150
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   AHAVGRV
- PhylomeDB:   Q0AHC3
- ProtClustDB:   PRK10887
- BioCyc:   NEUT335283:NEUT_1000-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 50041; Mature: 50041

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKYFGTDGIRGKVGEFPITPEFFLRLGYAVGKVLLASDWKLAADKRPTILIGKDTRIS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCEEECCCCCEEEEECCCCCH
GYMLESALEAGFSAAGVDVLLSGPLPTPAVAYLVRALRIQAGAVISASHNPFYDNGIKFF
HHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEE
SSEGSKLPDSMELQIEAELDFPIETAPSIKLGRVQRLKDEEGRYIEFCKSTFPNQLDLRG
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
WKIVVDCANGADYQVAGHVMHELGADVVTIHANPDGFNINHECGATHIMTLQGAVLQHGA
EEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEECCHHHHCCC
DFGIAVDGDGDRVLMVSGEGVVYDGDSLAYIIAKHRQQRGVLQGGVVGTLMTNLAVEQAF
CCEEEEECCCCEEEEEECCEEEECCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHH
ERIGIPFARANVGDRYVSELLQQNDWYLGAENSGHIICRDKHTTGDGIISALQVLYALRD
HHHCCCEEECCCCHHHHHHHHHCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
TGLMFADLMHDVTFFPQRLINVKISRDFDFQNDQAVEICKNEAEQALGNDGRILLRASGT
CCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCC
EPLIRVMVEGKDPQQIEYWAEKIAGTIQQQAVASTVGH
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKKYFGTDGIRGKVGEFPITPEFFLRLGYAVGKVLLASDWKLAADKRPTILIGKDTRIS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCEEECCCCCEEEEECCCCCH
GYMLESALEAGFSAAGVDVLLSGPLPTPAVAYLVRALRIQAGAVISASHNPFYDNGIKFF
HHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEE
SSEGSKLPDSMELQIEAELDFPIETAPSIKLGRVQRLKDEEGRYIEFCKSTFPNQLDLRG
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
WKIVVDCANGADYQVAGHVMHELGADVVTIHANPDGFNINHECGATHIMTLQGAVLQHGA
EEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEECCHHHHCCC
DFGIAVDGDGDRVLMVSGEGVVYDGDSLAYIIAKHRQQRGVLQGGVVGTLMTNLAVEQAF
CCEEEEECCCCEEEEEECCEEEECCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHH
ERIGIPFARANVGDRYVSELLQQNDWYLGAENSGHIICRDKHTTGDGIISALQVLYALRD
HHHCCCEEECCCCHHHHHHHHHCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
TGLMFADLMHDVTFFPQRLINVKISRDFDFQNDQAVEICKNEAEQALGNDGRILLRASGT
CCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCC
EPLIRVMVEGKDPQQIEYWAEKIAGTIQQQAVASTVGH
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA