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The map label for this gene is btuE [C]

Identifier: 114330994

GI number: 114330994

Start: 1023887

End: 1024363

Strand: Direct

Name: btuE [C]

Synonym: Neut_0992

Alternate gene names: 114330994

Gene position: 1023887-1024363 (Clockwise)

Preceding gene: 114330990

Following gene: 114330995

Centisome position: 38.48

GC content: 42.56

Gene sequence:

>477_bases
ATGGATATCTATGACTATGGTATAAAAACGATTGATGGGCAGAATAAACTGCTCAGCGATTATAAGGGTAAAGTCTTGCT
GATAGTGAACACGGCCAGTAAATGTGGTTTTACACCTCAGTATCAGAGTTTGGAAGCGTTATATCGACGATACAAGGATC
AGGGGCTGGTTGTACTTGCTTTTCCCTGTAACCAATTTGGCCGCCAGGAACCGGGTAATGAACGTGAAATTCAGGAATTT
TGCTCATCCGGTTACAACATCAGCTTTCCTTTATTTGCAAAGATTGAGGTGAATGGTACCAATACCCATCCGCTCTACCA
ATATCTGAAGAATGAAAAACCTGGTGTGCTGGGTTCCAAGGGTATCAAATGGAATTTCACCAAGTTTCTGGTAGATAGAA
CCGGGAAAGTGGTTAAACGTTATGCGCCAGTTGATAAGCCGGAATCTCTGGTTGGAGATATCGAACAGTTGCTCTAA

Upstream 100 bases:

>100_bases
TGGCAGTGGGATCAACAAAAGCACTTTCGTGGACGATCGGCTGATCACCCGTGGGGTTTTTTCTAATCATGATAATTTCT
GAGTAGCATTATAAATAGCG

Downstream 100 bases:

>100_bases
TTTTATTGAATGTTTGTCGTGTATGAATCTGGTTTCATCTCTTGATATTGATTTTTCAGCTCCCTCTGCTGAAGTGGCGC
GTTCCCTGATAGGCGTGACG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MDIYDYGIKTIDGQNKLLSDYKGKVLLIVNTASKCGFTPQYQSLEALYRRYKDQGLVVLAFPCNQFGRQEPGNEREIQEF
CSSGYNISFPLFAKIEVNGTNTHPLYQYLKNEKPGVLGSKGIKWNFTKFLVDRTGKVVKRYAPVDKPESLVGDIEQLL

Sequences:

>Translated_158_residues
MDIYDYGIKTIDGQNKLLSDYKGKVLLIVNTASKCGFTPQYQSLEALYRRYKDQGLVVLAFPCNQFGRQEPGNEREIQEF
CSSGYNISFPLFAKIEVNGTNTHPLYQYLKNEKPGVLGSKGIKWNFTKFLVDRTGKVVKRYAPVDKPESLVGDIEQLL
>Mature_158_residues
MDIYDYGIKTIDGQNKLLSDYKGKVLLIVNTASKCGFTPQYQSLEALYRRYKDQGLVVLAFPCNQFGRQEPGNEREIQEF
CSSGYNISFPLFAKIEVNGTNTHPLYQYLKNEKPGVLGSKGIKWNFTKFLVDRTGKVVKRYAPVDKPESLVGDIEQLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=47.0967741935484, Blast_Score=146, Evalue=8e-36,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=47.0967741935484, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI15618997, Length=158, Percent_Identity=43.0379746835443, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=47.3282442748092, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI192455698, Length=158, Percent_Identity=36.7088607594937, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI33186887, Length=170, Percent_Identity=40, Blast_Score=103, Evalue=7e-23,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=39.3063583815029, Blast_Score=100, Evalue=4e-22,
Organism=Homo sapiens, GI6006001, Length=159, Percent_Identity=40.8805031446541, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=34.6153846153846, Blast_Score=93, Evalue=8e-20,
Organism=Homo sapiens, GI32967607, Length=180, Percent_Identity=32.7777777777778, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788003, Length=160, Percent_Identity=46.875, Blast_Score=154, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=157, Percent_Identity=50.3184713375796, Blast_Score=157, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17535473, Length=157, Percent_Identity=49.6815286624204, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=45.2229299363057, Blast_Score=135, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=44.0993788819876, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17550320, Length=179, Percent_Identity=36.3128491620112, Blast_Score=117, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193209493, Length=179, Percent_Identity=34.6368715083799, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71999642, Length=75, Percent_Identity=45.3333333333333, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=39.3617021276596, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507603, Length=125, Percent_Identity=33.6, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193210709, Length=71, Percent_Identity=46.4788732394366, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=156, Percent_Identity=55.7692307692308, Blast_Score=191, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6322228, Length=155, Percent_Identity=56.7741935483871, Blast_Score=189, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322826, Length=157, Percent_Identity=47.7707006369427, Blast_Score=156, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=49.0566037735849, Blast_Score=146, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=49.0566037735849, Blast_Score=146, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=49.0566037735849, Blast_Score=145, Evalue=8e-36,
Organism=Drosophila melanogaster, GI85726443, Length=161, Percent_Identity=43.4782608695652, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17969; Mature: 17969

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIYDYGIKTIDGQNKLLSDYKGKVLLIVNTASKCGFTPQYQSLEALYRRYKDQGLVVLA
CCCCCCCCEEECCCHHHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHCCCCEEEEE
FPCNQFGRQEPGNEREIQEFCSSGYNISFPLFAKIEVNGTNTHPLYQYLKNEKPGVLGSK
ECCCHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCC
GIKWNFTKFLVDRTGKVVKRYAPVDKPESLVGDIEQLL
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MDIYDYGIKTIDGQNKLLSDYKGKVLLIVNTASKCGFTPQYQSLEALYRRYKDQGLVVLA
CCCCCCCCEEECCCHHHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHCCCCEEEEE
FPCNQFGRQEPGNEREIQEFCSSGYNISFPLFAKIEVNGTNTHPLYQYLKNEKPGVLGSK
ECCCHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCC
GIKWNFTKFLVDRTGKVVKRYAPVDKPESLVGDIEQLL
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]