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The map label for this gene is mdtA [H]

Identifier: 114330989

GI number: 114330989

Start: 1016537

End: 1017628

Strand: Direct

Name: mdtA [H]

Synonym: Neut_0987

Alternate gene names: 114330989

Gene position: 1016537-1017628 (Clockwise)

Preceding gene: 114330985

Following gene: 114330990

Centisome position: 38.2

GC content: 48.9

Gene sequence:

>1092_bases
GTGGTGTTGAGTAGGGCAGAGAAACTGTTGTGTATCGTTCTGATGCTGATGCTTACTGCTTGTGGTAAGCAGGAAGAGGT
TATAAAAATAGCTAACCCGCCAGCAGTCAGTGTAGCTACGGCCAGGAATGTGTCTATAGAAGTACGAGAGGAATCCATTG
GTTCACTGGAGGGCATAATGGATCCCACGATCGCGGCGGAAGTATCTGGGCGTGTCCTTAAAGTATTGGTGCGCCAGGGG
CAACATGTGAAAAAAGGACAGGAAATTGCTTTGTTGGATCCGGCGGATCATCAGCTGCTACGACGTGAAGCGCTCAGCGA
GGTGGCAAGACTGGAGGCGTTGCTGGAAAACCAACAGCGTTCAGTCGAACGTAATACCCGGCTGGTAGAACGAAATTTTA
TTTCCCAGATCGTGTTGGATGATGTCAAGACTCAGGAAATAGCATTGCGCCGGCAGCTGGAAGGAGCGAAATCCCGTCTG
GCCACAATTGAACATAATAAATCTAAGACACGCCTGTTTTCGCCAATGGATGGAAAAATTGAATCCCAGACCGTTGTTGA
GGGAGACTATGTCAAGGTTGGCGATCCGTTGCTACAAATTATCAGTAATCAGCATTTGCGTGCACATCTGCCATTCCCGG
AAAGTATTGCTTCATATATCAGACCGAATCTTGAAGTTAGGCTGAGCACACCTACCTCTGATACTGAAATTATTTCCCAT
ATCAGGGAATTGAAGCCTGCAATTGGTGTTAGCAATCGGGCGATTGATGCACTTGTCTATATTGAGAACCAGCCTGGTTG
GCACGCGGGTGCAAGCGTTAGTGGTGTGGTCATCCTTGGCGTGCGTGAGAATGTAGTGGTTGTGCCGGAGCAGAGTGTAG
TGCTCAGGCCGGCAGGCCAGGTGGTTTATGCTATCAATGGCGAGCAGGTTGAACAGCGTGTCGTGCGAACCGGATTAAAT
CAGGATGGAATGGTTGAAATCATTGATGGCGTACAAGCAGGTGAGCAGATAGTGCTGGATGGTGCAGCTTTTCTTACCGA
CGGCACCAAGGTCACTATACAAAGGGAAATACTGGGGCAAGCGAATTCATGA

Upstream 100 bases:

>100_bases
ACAGCTGTCTACCGAGTGATCCGGTAAATTTACAGCTGGGATAATCTTGATGTGGTAGATCACGTGGTTGCCATTTGTGG
ATTACAGGAGAGCGTTGACT

Downstream 100 bases:

>100_bases
CGCTGCCAGAGCTGTCGATCAAGCGCCATGTGCTGGCGTGGATGGTTTCAGGATTACTGGTATTGCTAGGTGTTATCAGT
TATCAGCGAATTGGAATGGA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MVLSRAEKLLCIVLMLMLTACGKQEEVIKIANPPAVSVATARNVSIEVREESIGSLEGIMDPTIAAEVSGRVLKVLVRQG
QHVKKGQEIALLDPADHQLLRREALSEVARLEALLENQQRSVERNTRLVERNFISQIVLDDVKTQEIALRRQLEGAKSRL
ATIEHNKSKTRLFSPMDGKIESQTVVEGDYVKVGDPLLQIISNQHLRAHLPFPESIASYIRPNLEVRLSTPTSDTEIISH
IRELKPAIGVSNRAIDALVYIENQPGWHAGASVSGVVILGVRENVVVVPEQSVVLRPAGQVVYAINGEQVEQRVVRTGLN
QDGMVEIIDGVQAGEQIVLDGAAFLTDGTKVTIQREILGQANS

Sequences:

>Translated_363_residues
MVLSRAEKLLCIVLMLMLTACGKQEEVIKIANPPAVSVATARNVSIEVREESIGSLEGIMDPTIAAEVSGRVLKVLVRQG
QHVKKGQEIALLDPADHQLLRREALSEVARLEALLENQQRSVERNTRLVERNFISQIVLDDVKTQEIALRRQLEGAKSRL
ATIEHNKSKTRLFSPMDGKIESQTVVEGDYVKVGDPLLQIISNQHLRAHLPFPESIASYIRPNLEVRLSTPTSDTEIISH
IRELKPAIGVSNRAIDALVYIENQPGWHAGASVSGVVILGVRENVVVVPEQSVVLRPAGQVVYAINGEQVEQRVVRTGLN
QDGMVEIIDGVQAGEQIVLDGAAFLTDGTKVTIQREILGQANS
>Mature_363_residues
MVLSRAEKLLCIVLMLMLTACGKQEEVIKIANPPAVSVATARNVSIEVREESIGSLEGIMDPTIAAEVSGRVLKVLVRQG
QHVKKGQEIALLDPADHQLLRREALSEVARLEALLENQQRSVERNTRLVERNFISQIVLDDVKTQEIALRRQLEGAKSRL
ATIEHNKSKTRLFSPMDGKIESQTVVEGDYVKVGDPLLQIISNQHLRAHLPFPESIASYIRPNLEVRLSTPTSDTEIISH
IRELKPAIGVSNRAIDALVYIENQPGWHAGASVSGVVILGVRENVVVVPEQSVVLRPAGQVVYAINGEQVEQRVVRTGLN
QDGMVEIIDGVQAGEQIVLDGAAFLTDGTKVTIQREILGQANS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=344, Percent_Identity=25, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789665, Length=355, Percent_Identity=24.7887323943662, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87081951, Length=186, Percent_Identity=22.0430107526882, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39783; Mature: 39783

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSRAEKLLCIVLMLMLTACGKQEEVIKIANPPAVSVATARNVSIEVREESIGSLEGIM
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEEEEHHHHCHHHHCC
DPTIAAEVSGRVLKVLVRQGQHVKKGQEIALLDPADHQLLRREALSEVARLEALLENQQR
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVERNTRLVERNFISQIVLDDVKTQEIALRRQLEGAKSRLATIEHNKSKTRLFSPMDGKI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCC
ESQTVVEGDYVKVGDPLLQIISNQHLRAHLPFPESIASYIRPNLEVRLSTPTSDTEIISH
CCCEEECCCEEECCHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEECCCCHHHHHHH
IRELKPAIGVSNRAIDALVYIENQPGWHAGASVSGVVILGVRENVVVVPEQSVVLRPAGQ
HHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCEEEECCCCEEEECCCC
VVYAINGEQVEQRVVRTGLNQDGMVEIIDGVQAGEQIVLDGAAFLTDGTKVTIQREILGQ
EEEEECHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCEEEECCCEEEEEHHHCCC
ANS
CCC
>Mature Secondary Structure
MVLSRAEKLLCIVLMLMLTACGKQEEVIKIANPPAVSVATARNVSIEVREESIGSLEGIM
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEEEEHHHHCHHHHCC
DPTIAAEVSGRVLKVLVRQGQHVKKGQEIALLDPADHQLLRREALSEVARLEALLENQQR
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVERNTRLVERNFISQIVLDDVKTQEIALRRQLEGAKSRLATIEHNKSKTRLFSPMDGKI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCC
ESQTVVEGDYVKVGDPLLQIISNQHLRAHLPFPESIASYIRPNLEVRLSTPTSDTEIISH
CCCEEECCCEEECCHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEECCCCHHHHHHH
IRELKPAIGVSNRAIDALVYIENQPGWHAGASVSGVVILGVRENVVVVPEQSVVLRPAGQ
HHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCEEEECCCCEEEECCCC
VVYAINGEQVEQRVVRTGLNQDGMVEIIDGVQAGEQIVLDGAAFLTDGTKVTIQREILGQ
EEEEECHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCEEEECCCEEEEEHHHCCC
ANS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA