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The map label for this gene is htpG

Identifier: 114330940

GI number: 114330940

Start: 964647

End: 966569

Strand: Direct

Name: htpG

Synonym: Neut_0937

Alternate gene names: 114330940

Gene position: 964647-966569 (Clockwise)

Preceding gene: 114330938

Following gene: 114330941

Centisome position: 36.25

GC content: 44.2

Gene sequence:

>1923_bases
ATGCAAACTGCAGAAAACGTCGAACACTTGAATTTTCAGGCTGAAGCGAAACAGCTTTTGAGGTTGATGATTCATTCCCT
TTACAGTAATAAGGAAATTTTTCTACGGGAGTTGATTTCGAATGCTTCGGATGCCGCAGACAAACTGAGGTTTGAAGGAT
TATCCGATACGGCATTATATGAATCCGATCCGGATCTTAAAATCCGTATTGCTTACGATAAAGAGGCGCGTACTATCACG
ATCAGCGATAATGGTATCGGTATGTCCAGACAGGAAGTGATTGATAATATTGGTACTATTGCCAAATCTGGTACACGGGA
ATTTATTGATTCGCTGACAGGTGACCAAGCTAGGGATGCCAACCTAATTGGACAGTTTGGCGTAGGTTTTTATTCGGCAT
TTATTGTTGCGGACAAAGTAACGTTGACTACTCGCCGTGCAGGCCTGACTACTGAGCATGGAGTGCGCTGGGAATCCAGT
GGTGAGGGTGAATACACGCTGGAAACCGTGGAAAAAAGGGATCGGGGTACAGAGGTTGTTTTGCATCTGCGTGAAGACGA
GGATGAGCTGTTAAGCAGCTTTCAGCTGCGTTCTATCATCCGCAAGTATTCAGATCACATCACGCTTCCTATCATTATGA
AGAAGGAGGTATGGGATGACGAGAGCAAGGCATACAAAATAAGTGATGAAGAAGAAACAGTCAATCAGGCCAGTGCAATC
TGGGCACGGCCTAAAAATGAGATTACGCAAGAACAGTACGATGAATTTTATAAACATGTAGCGCATGATTTCGAGCCGCC
GCTTGCTCATGTACATGCCAGAGTTGAAGGTAAGCAGGAGTATATTCAGTTGTTATATATTCCCGCCCATGCGCCGTTTG
ACCTGTTTGATCGCGAGCATCGTCATGGCCTCAAACTCTATATCAAACGTGTGTTTATCATGGATGATGCGGAGAAATTG
TTGCCAGGGTACTTGCGTTTCGTTCGCGGCATTATTGATTCAAACGATTTACCATTGAATGTTTCCCGTGAAATCCTGCA
AGAATCGAAAGATATTGACAGCATTCGTGCCGGCTCGGTGAAAAAAGTACTGGGGTTGATTGAAGATCTTGCAACGAGTG
ATAAGAGCGAGGATCAGGAAAAATTTAAAATCTTCTGGCGTGAATTTGGCCAGGTACTGAAAGAAGGAGTTGCGGAAGAT
TACAGCAACCGTGAACGTATCGCTAAATTGCTGAGATTTACTTCAACACATGATGAACAAGAAGAGCAGACGGTCTCGCT
GGATGATTACATCGCCCGGATGAAACCAGAACAGGAAAAAATTTACTACATTACTGCAGATGGTCTGAAGGCAGCCCAAA
GCAGCCCACATCTGGAAATATTCCGTAAAAAAGGGATCGAGGTTCTGTTGTTGCATGATCGTATTGATGAATGGCTGACA
GCCAATCTAAATGAGTATGCGGGTAAATCTTTACAATCTATTGCCAAAGGTGATCTGGATCTAGGCAAGCTGGAAGATGA
AGTAGAAAAGCAAGAGCATGAAAAGGAAGCAGGAGATTTTCAGGAATTAACAGCAAAAATGAAGGAAGTGCTGGGTGAGC
TAGTCAAGGATGTCCGCATTACCTACCGTTTGACGGAATCGCCAGCCTGTTTGGTAGCTGATACACACGATATGAGTGGT
AATCTCGGACGACTACTGAAATCTGCTGGTCAGAAAGTTCCGGATAGTAAACCGTTTCTGGAAATCAACCCGCATCATCC
CATGGTTCAGCGCCTGAAATATGAAGAAGCCAAATTTGCTGACTGGAGCCATATTTTGTTTGATCAGGCATTGCTGGCCG
AAGGGGGGCAGCTCGAAGATCCAGCTAGTTTCGTCAGACGATTGAATGATTTGCTGCTGCAAAATATTTTAAGCGGAAAA
TAA

Upstream 100 bases:

>100_bases
GAACAAGTAAAAATTAAGAAATAGAGGTTTCGAGATTGAAGTAACTTGAAATCGGGAAACCTGATCCCACAATGTTAGCG
CATTTTTTAAGGAGGAAAGT

Downstream 100 bases:

>100_bases
GATATCGAGGATTGGTTGTGCGCACACTATAAATTTGTCTAACAGTGTTTTTAAAATCCGGTTGTATAGAGTGAAAGCAC
AAGGTGCGCGAAGTTCAGCA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MQTAENVEHLNFQAEAKQLLRLMIHSLYSNKEIFLRELISNASDAADKLRFEGLSDTALYESDPDLKIRIAYDKEARTIT
ISDNGIGMSRQEVIDNIGTIAKSGTREFIDSLTGDQARDANLIGQFGVGFYSAFIVADKVTLTTRRAGLTTEHGVRWESS
GEGEYTLETVEKRDRGTEVVLHLREDEDELLSSFQLRSIIRKYSDHITLPIIMKKEVWDDESKAYKISDEEETVNQASAI
WARPKNEITQEQYDEFYKHVAHDFEPPLAHVHARVEGKQEYIQLLYIPAHAPFDLFDREHRHGLKLYIKRVFIMDDAEKL
LPGYLRFVRGIIDSNDLPLNVSREILQESKDIDSIRAGSVKKVLGLIEDLATSDKSEDQEKFKIFWREFGQVLKEGVAED
YSNRERIAKLLRFTSTHDEQEEQTVSLDDYIARMKPEQEKIYYITADGLKAAQSSPHLEIFRKKGIEVLLLHDRIDEWLT
ANLNEYAGKSLQSIAKGDLDLGKLEDEVEKQEHEKEAGDFQELTAKMKEVLGELVKDVRITYRLTESPACLVADTHDMSG
NLGRLLKSAGQKVPDSKPFLEINPHHPMVQRLKYEEAKFADWSHILFDQALLAEGGQLEDPASFVRRLNDLLLQNILSGK

Sequences:

>Translated_640_residues
MQTAENVEHLNFQAEAKQLLRLMIHSLYSNKEIFLRELISNASDAADKLRFEGLSDTALYESDPDLKIRIAYDKEARTIT
ISDNGIGMSRQEVIDNIGTIAKSGTREFIDSLTGDQARDANLIGQFGVGFYSAFIVADKVTLTTRRAGLTTEHGVRWESS
GEGEYTLETVEKRDRGTEVVLHLREDEDELLSSFQLRSIIRKYSDHITLPIIMKKEVWDDESKAYKISDEEETVNQASAI
WARPKNEITQEQYDEFYKHVAHDFEPPLAHVHARVEGKQEYIQLLYIPAHAPFDLFDREHRHGLKLYIKRVFIMDDAEKL
LPGYLRFVRGIIDSNDLPLNVSREILQESKDIDSIRAGSVKKVLGLIEDLATSDKSEDQEKFKIFWREFGQVLKEGVAED
YSNRERIAKLLRFTSTHDEQEEQTVSLDDYIARMKPEQEKIYYITADGLKAAQSSPHLEIFRKKGIEVLLLHDRIDEWLT
ANLNEYAGKSLQSIAKGDLDLGKLEDEVEKQEHEKEAGDFQELTAKMKEVLGELVKDVRITYRLTESPACLVADTHDMSG
NLGRLLKSAGQKVPDSKPFLEINPHHPMVQRLKYEEAKFADWSHILFDQALLAEGGQLEDPASFVRRLNDLLLQNILSGK
>Mature_640_residues
MQTAENVEHLNFQAEAKQLLRLMIHSLYSNKEIFLRELISNASDAADKLRFEGLSDTALYESDPDLKIRIAYDKEARTIT
ISDNGIGMSRQEVIDNIGTIAKSGTREFIDSLTGDQARDANLIGQFGVGFYSAFIVADKVTLTTRRAGLTTEHGVRWESS
GEGEYTLETVEKRDRGTEVVLHLREDEDELLSSFQLRSIIRKYSDHITLPIIMKKEVWDDESKAYKISDEEETVNQASAI
WARPKNEITQEQYDEFYKHVAHDFEPPLAHVHARVEGKQEYIQLLYIPAHAPFDLFDREHRHGLKLYIKRVFIMDDAEKL
LPGYLRFVRGIIDSNDLPLNVSREILQESKDIDSIRAGSVKKVLGLIEDLATSDKSEDQEKFKIFWREFGQVLKEGVAED
YSNRERIAKLLRFTSTHDEQEEQTVSLDDYIARMKPEQEKIYYITADGLKAAQSSPHLEIFRKKGIEVLLLHDRIDEWLT
ANLNEYAGKSLQSIAKGDLDLGKLEDEVEKQEHEKEAGDFQELTAKMKEVLGELVKDVRITYRLTESPACLVADTHDMSG
NLGRLLKSAGQKVPDSKPFLEINPHHPMVQRLKYEEAKFADWSHILFDQALLAEGGQLEDPASFVRRLNDLLLQNILSGK

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=680, Percent_Identity=40.5882352941176, Blast_Score=447, Evalue=1e-125,
Organism=Homo sapiens, GI4507677, Length=693, Percent_Identity=37.6623376623377, Blast_Score=423, Evalue=1e-118,
Organism=Homo sapiens, GI155722983, Length=643, Percent_Identity=34.6811819595645, Blast_Score=358, Evalue=8e-99,
Organism=Homo sapiens, GI154146191, Length=412, Percent_Identity=39.3203883495146, Blast_Score=280, Evalue=4e-75,
Organism=Homo sapiens, GI153792590, Length=412, Percent_Identity=39.3203883495146, Blast_Score=277, Evalue=3e-74,
Organism=Escherichia coli, GI1786679, Length=629, Percent_Identity=59.9364069952305, Blast_Score=759, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=675, Percent_Identity=38.962962962963, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17542208, Length=680, Percent_Identity=37.5, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI115535205, Length=647, Percent_Identity=33.3848531684699, Blast_Score=318, Evalue=7e-87,
Organism=Caenorhabditis elegans, GI115535167, Length=433, Percent_Identity=35.5658198614319, Blast_Score=251, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=39.2647058823529, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6325016, Length=684, Percent_Identity=38.8888888888889, Blast_Score=461, Evalue=1e-130,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=39.1240875912409, Blast_Score=467, Evalue=1e-131,
Organism=Drosophila melanogaster, GI21357739, Length=691, Percent_Identity=36.6136034732272, Blast_Score=407, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24586016, Length=651, Percent_Identity=33.6405529953917, Blast_Score=355, Evalue=8e-98,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_NITEC (Q0AHI5)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747162.1
- ProteinModelPortal:   Q0AHI5
- STRING:   Q0AHI5
- GeneID:   4271840
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0937
- NMPDR:   fig|335283.3.peg.1567
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   Q0AHI5
- ProtClustDB:   PRK05218
- BioCyc:   NEUT335283:NEUT_0937-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 73212; Mature: 73212

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTAENVEHLNFQAEAKQLLRLMIHSLYSNKEIFLRELISNASDAADKLRFEGLSDTALY
CCCHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
ESDPDLKIRIAYDKEARTITISDNGIGMSRQEVIDNIGTIAKSGTREFIDSLTGDQARDA
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
NLIGQFGVGFYSAFIVADKVTLTTRRAGLTTEHGVRWESSGEGEYTLETVEKRDRGTEVV
HHHHHHHHHHHHHHHHHCCEEEEEHHCCCCCCCCCEECCCCCCCEEHHHHHHCCCCCEEE
LHLREDEDELLSSFQLRSIIRKYSDHITLPIIMKKEVWDDESKAYKISDEEETVNQASAI
EEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHCCCCCCEEECCCHHHHHHHHHHH
WARPKNEITQEQYDEFYKHVAHDFEPPLAHVHARVEGKQEYIQLLYIPAHAPFDLFDREH
HCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHEEEEEEECCCCCHHHHCHHH
RHGLKLYIKRVFIMDDAEKLLPGYLRFVRGIIDSNDLPLNVSREILQESKDIDSIRAGSV
HCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHCCCH
KKVLGLIEDLATSDKSEDQEKFKIFWREFGQVLKEGVAEDYSNRERIAKLLRFTSTHDEQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCH
EEQTVSLDDYIARMKPEQEKIYYITADGLKAAQSSPHLEIFRKKGIEVLLLHDRIDEWLT
HHHHCCHHHHHHHCCCCCCEEEEEEECCCHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHH
ANLNEYAGKSLQSIAKGDLDLGKLEDEVEKQEHEKEAGDFQELTAKMKEVLGELVKDVRI
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEE
TYRLTESPACLVADTHDMSGNLGRLLKSAGQKVPDSKPFLEINPHHPMVQRLKYEEAKFA
EEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCCC
DWSHILFDQALLAEGGQLEDPASFVRRLNDLLLQNILSGK
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTAENVEHLNFQAEAKQLLRLMIHSLYSNKEIFLRELISNASDAADKLRFEGLSDTALY
CCCHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
ESDPDLKIRIAYDKEARTITISDNGIGMSRQEVIDNIGTIAKSGTREFIDSLTGDQARDA
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
NLIGQFGVGFYSAFIVADKVTLTTRRAGLTTEHGVRWESSGEGEYTLETVEKRDRGTEVV
HHHHHHHHHHHHHHHHHCCEEEEEHHCCCCCCCCCEECCCCCCCEEHHHHHHCCCCCEEE
LHLREDEDELLSSFQLRSIIRKYSDHITLPIIMKKEVWDDESKAYKISDEEETVNQASAI
EEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHCCCCCCEEECCCHHHHHHHHHHH
WARPKNEITQEQYDEFYKHVAHDFEPPLAHVHARVEGKQEYIQLLYIPAHAPFDLFDREH
HCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHEEEEEEECCCCCHHHHCHHH
RHGLKLYIKRVFIMDDAEKLLPGYLRFVRGIIDSNDLPLNVSREILQESKDIDSIRAGSV
HCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHCCCH
KKVLGLIEDLATSDKSEDQEKFKIFWREFGQVLKEGVAEDYSNRERIAKLLRFTSTHDEQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCH
EEQTVSLDDYIARMKPEQEKIYYITADGLKAAQSSPHLEIFRKKGIEVLLLHDRIDEWLT
HHHHCCHHHHHHHCCCCCCEEEEEEECCCHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHH
ANLNEYAGKSLQSIAKGDLDLGKLEDEVEKQEHEKEAGDFQELTAKMKEVLGELVKDVRI
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEE
TYRLTESPACLVADTHDMSGNLGRLLKSAGQKVPDSKPFLEINPHHPMVQRLKYEEAKFA
EEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCCC
DWSHILFDQALLAEGGQLEDPASFVRRLNDLLLQNILSGK
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA