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The map label for this gene is insF1 [H]

Identifier: 114330891

GI number: 114330891

Start: 904797

End: 905624

Strand: Direct

Name: insF1 [H]

Synonym: Neut_0887

Alternate gene names: 114330891

Gene position: 904797-905624 (Clockwise)

Preceding gene: 114330890

Following gene: 114330894

Centisome position: 34.0

GC content: 45.77

Gene sequence:

>828_bases
ATGTGCCGACTCATGGGTGTAAGCCGCAGTGCCTACTATGATTACGTTCGTTGTGCTAACAATTGTTCTACCGACCCGTG
CCATATAGAAATACTTGGAGCAGTACGGGAGATAGCAAAATCCAGTCATCATAGCTATGGCAGTCGCAGAATCGGAAAAG
CGCTGAATGCACGGGGTTATCCGGTTGGTCGCAGGAAGGCTCGAAGCCTGATGCAAGAAGCAGATGTGCAAGTGAGGCAC
CGGAAAAAGTACAAGGTCACAACTAACAGTAATCACAAACAACCGATATTTGAGAATAGGCTGAATCGGCAATTTGATGT
TGCAGCCCCCAATCAAATCTACGTTGGTGACATTACCTGCATTTGGACCCGGGAAGGCTGGTTGTATCTGGCGGTGGTCA
TTGATTTGTTTTCCAGGAAGGTGGTGGGTTGGAGCATGAGTTCAAGAATGAAAGCAAAGCTGGTTTGTGATGCATTGAGA
ATGGCTGCCTGGCAGCGTCAACCACAACCTGGATTGATTGTACATTCAGATCGTGGATCGCAATATGCCAGCAAGCAGTA
CCGCCAACTTTTAAAAATACACGGCTTTATCGGCAGTATGAGTCGTAGGGGAAATTGTTGGGATAATTCAGTGGCTGAAA
GCTTTTTCGGTAGCCTTAAACGGGAGCAAATCCACTGGCAACATTATCCAACCCGCCATAAAGCACAACAAGATGTACTG
CAGTATATTTCCATGTTCTATAACAGCCAGCGACTGCATTCATACCCGGGTTACAAAAACCCGAATCAATATGAGATGGA
AATGGAAATAGTGAAAAATGTTGCTTAA

Upstream 100 bases:

>100_bases
AGAAGCGCATCTTAAAGGAAGCGACGGTCTTTTTCGCGAAAGAAACGAAGTGAAATATTCGTTTATCACCCAAAGGAAAA
AGACCTATCCGGTCGGCTTG

Downstream 100 bases:

>100_bases
CTAGAGTGTCCGGTTTTACTTGACCAGGTCAGTTCACTTGACCCGTGGGTGCGGCTTTACATGGTGAGAGATTTAGCCCT
AACAAGGCAAATCACCGGCA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MCRLMGVSRSAYYDYVRCANNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGYPVGRRKARSLMQEADVQVRH
RKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALR
MAAWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
QYISMFYNSQRLHSYPGYKNPNQYEMEMEIVKNVA

Sequences:

>Translated_275_residues
MCRLMGVSRSAYYDYVRCANNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGYPVGRRKARSLMQEADVQVRH
RKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALR
MAAWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
QYISMFYNSQRLHSYPGYKNPNQYEMEMEIVKNVA
>Mature_275_residues
MCRLMGVSRSAYYDYVRCANNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGYPVGRRKARSLMQEADVQVRH
RKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALR
MAAWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
QYISMFYNSQRLHSYPGYKNPNQYEMEMEIVKNVA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=233, Percent_Identity=35.6223175965665, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1788405, Length=270, Percent_Identity=41.8518518518518, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1787263, Length=270, Percent_Identity=41.8518518518518, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1786753, Length=270, Percent_Identity=41.8518518518518, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1786570, Length=270, Percent_Identity=41.8518518518518, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1786490, Length=270, Percent_Identity=41.8518518518518, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1789981, Length=256, Percent_Identity=30.46875, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32002; Mature: 32002

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRLMGVSRSAYYDYVRCANNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGY
CCCEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
PVGRRKARSLMQEADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITC
CCHHHHHHHHHHHHCHHHHHCCEEEEECCCCCCCCHHHHHCCCEEECCCCCEEEEEEEEE
IWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALRMAAWQRQPQPGLIVHSDRGS
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
QYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QYISMFYNSQRLHSYPGYKNPNQYEMEMEIVKNVA
HHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MCRLMGVSRSAYYDYVRCANNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGY
CCCEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
PVGRRKARSLMQEADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITC
CCHHHHHHHHHHHHCHHHHHCCEEEEECCCCCCCCHHHHHCCCEEECCCCCEEEEEEEEE
IWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALRMAAWQRQPQPGLIVHSDRGS
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
QYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QYISMFYNSQRLHSYPGYKNPNQYEMEMEIVKNVA
HHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]