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The map label for this gene is glnS1 [H]

Identifier: 114330877

GI number: 114330877

Start: 890266

End: 891963

Strand: Reverse

Name: glnS1 [H]

Synonym: Neut_0871

Alternate gene names: 114330877

Gene position: 891963-890266 (Counterclockwise)

Preceding gene: 114330881

Following gene: 114330876

Centisome position: 33.52

GC content: 48.53

Gene sequence:

>1698_bases
GTGAACACACCTTCAGCCCCTACTCATTTCATTCGTAATATCATTGAAGAAGACAACCGCACCGGTAAGTGGAACGGGCG
CGTAGAGACACGCTTCCCGCCCGAGCCAAATGGCTATCTGCATATCGGCCATGCAAAAAGCATTTGCTTGAATTTCGGGC
TTGCGCTTGAATATAACGGCGCCTGTCATCTGCGATTCGACGATACAAACCCGGAAAAAGAAGCTCAGGAATACGTCGAT
GCCATTATTGAATCAGTCCACTGGCTGGGCTTTGACTGGCAGGAACATCTTTACTACGCTTCCGATTATTTTGATCAGCT
ATATGAATTTGCAGAATATCTGATCACGCAAGACAAGGCCTATGTGGACAGCCTATCGGCAGATGAAATCCGCCGATTAC
GTGGAACCTTGACTGAAGCAGGTACAAACAGCCCTTATCGTGATCGTCCGCCATCCGAAAGTCTGGATTTGTTCCGGCGC
ATGCGCGCAAGAGAGTTTCCGGATGGCGCGCACGTACTACGCGCCAAAATTGATATGGCATCCCCCAACATCAATATGCG
TGATCCGGTTATCTATCGCATCCGCCATATCCGCCACCAGCGCACGGGTGATAAATGGTGTATCTACCCGATGTACGATT
ACACCCATTGTATTTCCGATGCTTTGGAGCGGATCACGCATTCCCTTTGCACACTGGAGTTTGAAGATCATCGGCCACTG
TATGACTGGATACTGGATCAATTAAGTGAAAAAGTTCCCTGCCACCCGCAGCAGATCGAGTTTGCGCGACTGAATCTGAC
TTACAGTGTCATGAGCAAGCGTAAACTGATCGAACTGGTAGAGAACAAACTGGTAGATGGCTGGGACGATCCACGCATGA
ATACATTGGCAGGTCTGCGCCGTCGGGGCTATACGCCGGAATCAATCCGCTTGTTTGCGGAACGAATCGGTATCAGTAAG
GCAGATTCCTGGATTGATATGACAGTGCTGGAAGATTGCTTACGCGAAGACCTTAATGAAAACGCACCGCGCCGCATCGC
TGTCCTTAATCCGGTGCTGCTGGTCATAGATAACTTTCCAGATGATCAGATGGAAACCTGCTATGCACCCAATCATCCAA
AAAAACTCGAACTTGGCACACGCGAACTACCGCTGACAAAACGGCTTTATATTGACCGTGAAGACTTTATGGAGGTGCCA
GACAAAGGCTTCTTCCGCCTGGCACCTGGGGCAGAAGTGCGGTTACGTTATGCATATATCGTAAGATGCACACATCTTGT
CAAAGATGATCAGGGAAAGATCCTGGAGATTCACTGCACTTACGATCCCGCTACCAAAAGCGGTACTGCCGGGGCTGAAA
CCCGAAAAGTCCGTGGCAATATTCACTGGCTGTCAGCTACTTATGCCAAGGCTGTTGAAATCAGATTATATGACCGTTTG
TTCAGCGACGCACATCCCGACACGGAAGGTAAAGATTTCAAAACCTCGTTAAATCCGGATTCCAGGAAAATTATTGTCGG
GTACGTTGAACCTTCTTTACTTGAAATTCAAGCAGAACAGCGTTTTCAGTTTGAACGCCATGGCTACTTTGTAGCTGATC
TGGCAGATACAAAACCGGGAAAGCCGATATTCAATCGAACCGTATCACTACGCAATACCTGGGTGAAAATCACGGACAAG
CCGGAGCACAGTGGATAA

Upstream 100 bases:

>100_bases
ACGGCATCGCACGCTGCCTGGGCACATATTACGATCTATGTACTGTCATTTATTCCATGAAAATAATCAACATCTTATTG
AATTCAACTGAAAAATATCT

Downstream 100 bases:

>100_bases
TCAGCAATTGTGTGAATTACATTTGCATATATGACAAATTACCAGGACATTCGCTAAAAAGAACCTTTCTTATTTCACAA
CCAGATTATTTTCTTGTTAT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MNTPSAPTHFIRNIIEEDNRTGKWNGRVETRFPPEPNGYLHIGHAKSICLNFGLALEYNGACHLRFDDTNPEKEAQEYVD
AIIESVHWLGFDWQEHLYYASDYFDQLYEFAEYLITQDKAYVDSLSADEIRRLRGTLTEAGTNSPYRDRPPSESLDLFRR
MRAREFPDGAHVLRAKIDMASPNINMRDPVIYRIRHIRHQRTGDKWCIYPMYDYTHCISDALERITHSLCTLEFEDHRPL
YDWILDQLSEKVPCHPQQIEFARLNLTYSVMSKRKLIELVENKLVDGWDDPRMNTLAGLRRRGYTPESIRLFAERIGISK
ADSWIDMTVLEDCLREDLNENAPRRIAVLNPVLLVIDNFPDDQMETCYAPNHPKKLELGTRELPLTKRLYIDREDFMEVP
DKGFFRLAPGAEVRLRYAYIVRCTHLVKDDQGKILEIHCTYDPATKSGTAGAETRKVRGNIHWLSATYAKAVEIRLYDRL
FSDAHPDTEGKDFKTSLNPDSRKIIVGYVEPSLLEIQAEQRFQFERHGYFVADLADTKPGKPIFNRTVSLRNTWVKITDK
PEHSG

Sequences:

>Translated_565_residues
MNTPSAPTHFIRNIIEEDNRTGKWNGRVETRFPPEPNGYLHIGHAKSICLNFGLALEYNGACHLRFDDTNPEKEAQEYVD
AIIESVHWLGFDWQEHLYYASDYFDQLYEFAEYLITQDKAYVDSLSADEIRRLRGTLTEAGTNSPYRDRPPSESLDLFRR
MRAREFPDGAHVLRAKIDMASPNINMRDPVIYRIRHIRHQRTGDKWCIYPMYDYTHCISDALERITHSLCTLEFEDHRPL
YDWILDQLSEKVPCHPQQIEFARLNLTYSVMSKRKLIELVENKLVDGWDDPRMNTLAGLRRRGYTPESIRLFAERIGISK
ADSWIDMTVLEDCLREDLNENAPRRIAVLNPVLLVIDNFPDDQMETCYAPNHPKKLELGTRELPLTKRLYIDREDFMEVP
DKGFFRLAPGAEVRLRYAYIVRCTHLVKDDQGKILEIHCTYDPATKSGTAGAETRKVRGNIHWLSATYAKAVEIRLYDRL
FSDAHPDTEGKDFKTSLNPDSRKIIVGYVEPSLLEIQAEQRFQFERHGYFVADLADTKPGKPIFNRTVSLRNTWVKITDK
PEHSG
>Mature_565_residues
MNTPSAPTHFIRNIIEEDNRTGKWNGRVETRFPPEPNGYLHIGHAKSICLNFGLALEYNGACHLRFDDTNPEKEAQEYVD
AIIESVHWLGFDWQEHLYYASDYFDQLYEFAEYLITQDKAYVDSLSADEIRRLRGTLTEAGTNSPYRDRPPSESLDLFRR
MRAREFPDGAHVLRAKIDMASPNINMRDPVIYRIRHIRHQRTGDKWCIYPMYDYTHCISDALERITHSLCTLEFEDHRPL
YDWILDQLSEKVPCHPQQIEFARLNLTYSVMSKRKLIELVENKLVDGWDDPRMNTLAGLRRRGYTPESIRLFAERIGISK
ADSWIDMTVLEDCLREDLNENAPRRIAVLNPVLLVIDNFPDDQMETCYAPNHPKKLELGTRELPLTKRLYIDREDFMEVP
DKGFFRLAPGAEVRLRYAYIVRCTHLVKDDQGKILEIHCTYDPATKSGTAGAETRKVRGNIHWLSATYAKAVEIRLYDRL
FSDAHPDTEGKDFKTSLNPDSRKIIVGYVEPSLLEIQAEQRFQFERHGYFVADLADTKPGKPIFNRTVSLRNTWVKITDK
PEHSG

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=534, Percent_Identity=44.5692883895131, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI62241042, Length=528, Percent_Identity=32.3863636363636, Blast_Score=256, Evalue=5e-68,
Organism=Escherichia coli, GI1786895, Length=553, Percent_Identity=58.2278481012658, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=123, Percent_Identity=30.0813008130081, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=541, Percent_Identity=39.1866913123845, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17511007, Length=527, Percent_Identity=31.4990512333966, Blast_Score=228, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6324742, Length=570, Percent_Identity=41.7543859649123, Blast_Score=416, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321192, Length=520, Percent_Identity=33.8461538461538, Blast_Score=250, Evalue=3e-67,
Organism=Drosophila melanogaster, GI17864488, Length=551, Percent_Identity=41.3793103448276, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24649466, Length=523, Percent_Identity=32.1223709369025, Blast_Score=239, Evalue=4e-63,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65749; Mature: 65749

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPSAPTHFIRNIIEEDNRTGKWNGRVETRFPPEPNGYLHIGHAKSICLNFGLALEYNG
CCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEEECCHHHHHHHCCEEEEECC
ACHLRFDDTNPEKEAQEYVDAIIESVHWLGFDWQEHLYYASDYFDQLYEFAEYLITQDKA
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVDSLSADEIRRLRGTLTEAGTNSPYRDRPPSESLDLFRRMRAREFPDGAHVLRAKIDMA
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEEEEEC
SPNINMRDPVIYRIRHIRHQRTGDKWCIYPMYDYTHCISDALERITHSLCTLEFEDHRPL
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEECCCCCH
YDWILDQLSEKVPCHPQQIEFARLNLTYSVMSKRKLIELVENKLVDGWDDPRMNTLAGLR
HHHHHHHHHHCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RRGYTPESIRLFAERIGISKADSWIDMTVLEDCLREDLNENAPRRIAVLNPVLLVIDNFP
HCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEECCC
DDQMETCYAPNHPKKLELGTRELPLTKRLYIDREDFMEVPDKGFFRLAPGAEVRLRYAYI
CCHHHHCCCCCCCCEECCCCCCCCCHHHEEECHHHHHCCCCCCCEEECCCCCEEEEEHHH
VRCTHLVKDDQGKILEIHCTYDPATKSGTAGAETRKVRGNIHWLSATYAKAVEIRLYDRL
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHEEECCEEEEEEHHHHHHHHHHHHHH
FSDAHPDTEGKDFKTSLNPDSRKIIVGYVEPSLLEIQAEQRFQFERHGYFVADLADTKPG
HHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHCCEEEEEECCCCCC
KPIFNRTVSLRNTWVKITDKPEHSG
CHHHHCEEEECEEEEEEECCCCCCC
>Mature Secondary Structure
MNTPSAPTHFIRNIIEEDNRTGKWNGRVETRFPPEPNGYLHIGHAKSICLNFGLALEYNG
CCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEEECCHHHHHHHCCEEEEECC
ACHLRFDDTNPEKEAQEYVDAIIESVHWLGFDWQEHLYYASDYFDQLYEFAEYLITQDKA
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVDSLSADEIRRLRGTLTEAGTNSPYRDRPPSESLDLFRRMRAREFPDGAHVLRAKIDMA
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEEEEEC
SPNINMRDPVIYRIRHIRHQRTGDKWCIYPMYDYTHCISDALERITHSLCTLEFEDHRPL
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEECCCCCH
YDWILDQLSEKVPCHPQQIEFARLNLTYSVMSKRKLIELVENKLVDGWDDPRMNTLAGLR
HHHHHHHHHHCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RRGYTPESIRLFAERIGISKADSWIDMTVLEDCLREDLNENAPRRIAVLNPVLLVIDNFP
HCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEECCC
DDQMETCYAPNHPKKLELGTRELPLTKRLYIDREDFMEVPDKGFFRLAPGAEVRLRYAYI
CCHHHHCCCCCCCCEECCCCCCCCCHHHEEECHHHHHCCCCCCCEEECCCCCEEEEEHHH
VRCTHLVKDDQGKILEIHCTYDPATKSGTAGAETRKVRGNIHWLSATYAKAVEIRLYDRL
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHEEECCEEEEEEHHHHHHHHHHHHHH
FSDAHPDTEGKDFKTSLNPDSRKIIVGYVEPSLLEIQAEQRFQFERHGYFVADLADTKPG
HHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHCCEEEEEECCCCCC
KPIFNRTVSLRNTWVKITDKPEHSG
CHHHHCEEEECEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]