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The map label for this gene is yfbQ [H]

Identifier: 114330872

GI number: 114330872

Start: 884366

End: 885592

Strand: Reverse

Name: yfbQ [H]

Synonym: Neut_0866

Alternate gene names: 114330872

Gene position: 885592-884366 (Counterclockwise)

Preceding gene: 114330876

Following gene: 114330871

Centisome position: 33.28

GC content: 51.51

Gene sequence:

>1227_bases
ATGCAACCCATCAAAAAATCCAGCAAACTCAACCATGTCTGCTATGACATACGGGGACCGGTTCTTGATCGTGCCAGACA
GATGGAGGAAGATGGGCATCGTATCATCAAGCTCAATATCGGCAACCCTGCTTCCTTCGGGTTTGAAGCGCCGGACGAAA
TCTTGCAGGATGTCATCCAAAACCTTTCTGCCGCATCCGGTTATTGCGATTCCAAAGGGCTGTTCGCCGCTCGTAAAGCG
ATCATGCATTACACGCAGGAAAAAAATATCGCCAACGTGCGGATGGATGACATCTACGTCGGGAATGGCGTATCAGAACT
GATCATGCTGGCTACCCAGGCGCTGCTGGAAAATGATGATGAAGTGCTGGTTCCCTCGCCGGATTATCCCTTATGGACGG
CTGCAGTCTCTCTGGCGGGCGGAATCGCGCGACATTATATATGCGACGAACAATCTGACTGGCTGCCGGATCCGGAAAAC
ATAAAAGCCAAGGTCAACAGCAGAACCCGGGCAATCGTCATCATCAACCCCAACAACCCTACTGGCGCACTGTATCCGGA
TGATTTGTTGCGCGATATCATAGAAATTGCCCGACAAAACAACCTGATCATTTTTGCTGACGAAATCTACGACAAAATCC
TTTATGACTCTGCCCGCCATACTTCAATTGCCTCGTTGGCCAATGATGTTCCATTTGTAACATTCAACGGCTTATCCAAA
AATTATCGCGCCGCTGGCTTTCGTTCCGGCTGGGCAGTTGTCTCCGGCGACAAAACACGAGCGCGGGATTACATTGCCGG
GCTCAATATGCTGGCATCCATGCGTTTGTGCGCCAATGTTCCAGCACAATTCGGCATCCAGACTGCACTGGGTGGCTATC
AAAGTATTCACGATCTCACCATGCCCACCGGGCGGCTAAAGCGCCAGCGTGACCTGGCCTGGAAACTGCTCACCGACATT
CCGGGCGTGACCTGCGTTAAACCCCAAAGCGCACTGTACCTGTTCCCGCGGTTGGACCCCGCCTATTATCCGATTACAGA
TGATGAACAATTTGCACTGGATCTGCTACTGGAAGAAAAGGTACTCATCGTTCAGGGAACCGGGTTCAACTGGTCTCAGC
CCGATCATTTCCGGATTGTATTTCTGCCTAACAGTGACGATCTAACCGAAGCCATCGGCCGTATCGCACAGTTTTTAGGC
CGCTATCGCGCTCGTCACAGCTGCTAA

Upstream 100 bases:

>100_bases
CATCCCGCACAGCTGAGTTTTTAGAAATGTCCTTTAATAAAAATCAGCGTAACATGGTATGCTTTTTCCGTATTTTAAAT
AGAATTTTCTCTATCCGTCC

Downstream 100 bases:

>100_bases
TCCTACCTCCTGGAAAGCACGGTAACCAAGCGGGTAACTAACGTACTCCACTTTATTCCGTATATAATCTTCGGTTTATC
CTTATTGATACACAAAAAAT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MQPIKKSSKLNHVCYDIRGPVLDRARQMEEDGHRIIKLNIGNPASFGFEAPDEILQDVIQNLSAASGYCDSKGLFAARKA
IMHYTQEKNIANVRMDDIYVGNGVSELIMLATQALLENDDEVLVPSPDYPLWTAAVSLAGGIARHYICDEQSDWLPDPEN
IKAKVNSRTRAIVIINPNNPTGALYPDDLLRDIIEIARQNNLIIFADEIYDKILYDSARHTSIASLANDVPFVTFNGLSK
NYRAAGFRSGWAVVSGDKTRARDYIAGLNMLASMRLCANVPAQFGIQTALGGYQSIHDLTMPTGRLKRQRDLAWKLLTDI
PGVTCVKPQSALYLFPRLDPAYYPITDDEQFALDLLLEEKVLIVQGTGFNWSQPDHFRIVFLPNSDDLTEAIGRIAQFLG
RYRARHSC

Sequences:

>Translated_408_residues
MQPIKKSSKLNHVCYDIRGPVLDRARQMEEDGHRIIKLNIGNPASFGFEAPDEILQDVIQNLSAASGYCDSKGLFAARKA
IMHYTQEKNIANVRMDDIYVGNGVSELIMLATQALLENDDEVLVPSPDYPLWTAAVSLAGGIARHYICDEQSDWLPDPEN
IKAKVNSRTRAIVIINPNNPTGALYPDDLLRDIIEIARQNNLIIFADEIYDKILYDSARHTSIASLANDVPFVTFNGLSK
NYRAAGFRSGWAVVSGDKTRARDYIAGLNMLASMRLCANVPAQFGIQTALGGYQSIHDLTMPTGRLKRQRDLAWKLLTDI
PGVTCVKPQSALYLFPRLDPAYYPITDDEQFALDLLLEEKVLIVQGTGFNWSQPDHFRIVFLPNSDDLTEAIGRIAQFLG
RYRARHSC
>Mature_408_residues
MQPIKKSSKLNHVCYDIRGPVLDRARQMEEDGHRIIKLNIGNPASFGFEAPDEILQDVIQNLSAASGYCDSKGLFAARKA
IMHYTQEKNIANVRMDDIYVGNGVSELIMLATQALLENDDEVLVPSPDYPLWTAAVSLAGGIARHYICDEQSDWLPDPEN
IKAKVNSRTRAIVIINPNNPTGALYPDDLLRDIIEIARQNNLIIFADEIYDKILYDSARHTSIASLANDVPFVTFNGLSK
NYRAAGFRSGWAVVSGDKTRARDYIAGLNMLASMRLCANVPAQFGIQTALGGYQSIHDLTMPTGRLKRQRDLAWKLLTDI
PGVTCVKPQSALYLFPRLDPAYYPITDDEQFALDLLLEEKVLIVQGTGFNWSQPDHFRIVFLPNSDDLTEAIGRIAQFLG
RYRARHSC

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=390, Percent_Identity=25.6410256410256, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI19263340, Length=463, Percent_Identity=24.8380129589633, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=24.3303571428571, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=26.0869565217391, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI95147551, Length=238, Percent_Identity=27.3109243697479, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI169881279, Length=238, Percent_Identity=27.3109243697479, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI56713254, Length=167, Percent_Identity=26.3473053892216, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI56713256, Length=167, Percent_Identity=26.3473053892216, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI169881281, Length=119, Percent_Identity=31.9327731092437, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1788627, Length=403, Percent_Identity=65.0124069478908, Blast_Score=560, Evalue=1e-161,
Organism=Escherichia coli, GI1788722, Length=393, Percent_Identity=27.2264631043257, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786816, Length=408, Percent_Identity=23.0392156862745, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=29.4736842105263, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71981209, Length=468, Percent_Identity=24.5726495726496, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71981215, Length=292, Percent_Identity=25.6849315068493, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=235, Percent_Identity=28.5106382978723, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=235, Percent_Identity=28.5106382978723, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=236, Percent_Identity=26.6949152542373, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=477, Percent_Identity=24.1090146750524, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=475, Percent_Identity=24.2105263157895, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=173, Percent_Identity=26.0115606936416, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=29.5811518324607, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24641770, Length=466, Percent_Identity=25.3218884120172, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641760, Length=466, Percent_Identity=25.3218884120172, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641768, Length=466, Percent_Identity=25.3218884120172, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641766, Length=466, Percent_Identity=25.3218884120172, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641764, Length=466, Percent_Identity=25.3218884120172, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI45551451, Length=466, Percent_Identity=25.3218884120172, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573069, Length=256, Percent_Identity=23.4375, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24646114, Length=256, Percent_Identity=23.4375, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28573067, Length=256, Percent_Identity=23.4375, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28573065, Length=256, Percent_Identity=23.4375, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45574; Mature: 45574

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPIKKSSKLNHVCYDIRGPVLDRARQMEEDGHRIIKLNIGNPASFGFEAPDEILQDVIQ
CCCCCCCCCCCHHEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLSAASGYCDSKGLFAARKAIMHYTQEKNIANVRMDDIYVGNGVSELIMLATQALLENDD
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCC
EVLVPSPDYPLWTAAVSLAGGIARHYICDEQSDWLPDPENIKAKVNSRTRAIVIINPNNP
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEEEEECCCC
TGALYPDDLLRDIIEIARQNNLIIFADEIYDKILYDSARHTSIASLANDVPFVTFNGLSK
CCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCC
NYRAAGFRSGWAVVSGDKTRARDYIAGLNMLASMRLCANVPAQFGIQTALGGYQSIHDLT
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHCCHHHHHHHC
MPTGRLKRQRDLAWKLLTDIPGVTCVKPQSALYLFPRLDPAYYPITDDEQFALDLLLEEK
CCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCC
VLIVQGTGFNWSQPDHFRIVFLPNSDDLTEAIGRIAQFLGRYRARHSC
EEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQPIKKSSKLNHVCYDIRGPVLDRARQMEEDGHRIIKLNIGNPASFGFEAPDEILQDVIQ
CCCCCCCCCCCHHEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLSAASGYCDSKGLFAARKAIMHYTQEKNIANVRMDDIYVGNGVSELIMLATQALLENDD
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCC
EVLVPSPDYPLWTAAVSLAGGIARHYICDEQSDWLPDPENIKAKVNSRTRAIVIINPNNP
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEEEEECCCC
TGALYPDDLLRDIIEIARQNNLIIFADEIYDKILYDSARHTSIASLANDVPFVTFNGLSK
CCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCC
NYRAAGFRSGWAVVSGDKTRARDYIAGLNMLASMRLCANVPAQFGIQTALGGYQSIHDLT
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHCCHHHHHHHC
MPTGRLKRQRDLAWKLLTDIPGVTCVKPQSALYLFPRLDPAYYPITDDEQFALDLLLEEK
CCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCC
VLIVQGTGFNWSQPDHFRIVFLPNSDDLTEAIGRIAQFLGRYRARHSC
EEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]