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The map label for this gene is pfp [H]

Identifier: 114330800

GI number: 114330800

Start: 804906

End: 806165

Strand: Reverse

Name: pfp [H]

Synonym: Neut_0787

Alternate gene names: 114330800

Gene position: 806165-804906 (Counterclockwise)

Preceding gene: 114330807

Following gene: 114330799

Centisome position: 30.29

GC content: 48.65

Gene sequence:

>1260_bases
ATGACTATAAAAAATGCATTCTATGCCCAATCTGGCGGTGTAACGGCTGTAATCAATGCTTCAGCGGCAGGTTTACTGGA
AACAGCACGTGCACACCCGGATAAAATTGGAAACGTTTATGCCGGTCGCAATGGCATTATCGGGGCACTCACTGAAGACT
TAATTGATACCGGCGCAGAGCCCCTCGAAGCAATCCGGGCATTGCGCCACACACCATCCGGCGCTTTTGGCTCCTGTCGC
TACAAACTGAAAAGCCTTGAAGATAACCGACGGGAATACGAACGTCTGATAAAAATATTCAAGGCCCATAATATCGGCTA
CTTTTTCTATAACGGTGGCGGCGATTCGGCCGATACCTGCCTAAAAGTCTCACAGCTGGCCGATACACTCGGCTATCCAA
TCCAGGCAATTCACATACCCAAGACAGTTGACAATGATCTGCCCGTCACGGATTGTTGCCCAGGGTTTGGTTCAGTTGCC
AAATATGTAGCTGTTTCCATGCTGGAAGCCAGTTTTGATGTCGCCAGTATGGCCAAGACTTCAACCAAAGTGTTCATTCT
GGAAGTGATGGGGCGTCATGCTGGATGGATTGCAGCCGCAGGCGGGTTGGCGTCCAGCAAGGATCGTCATGTCCCAATTA
TCATCCTGTTTCCAGAAGTTACATTCGATGAAGAGAAATTCTTGGCCAAAACGGATCGTTACGTCAAGGAATACGGTTAT
TGTACGGTGGTGGTATCAGAGGGAGTGAAAGGAGCTGACGGCAAATTTCTGTCCGATCAGGGATTGCGCGATGCGTTTGG
ACATGCGCAGCTGGGTGGTGTGGCGCCAGTAATCGCAAATATGGTCAGAAATGGCCTGGGATTAAAATATCATTGGGGAG
TCTCGGATTATCTGCAGCGTGCTGCCCGGCATATTGCTTCCCGAACAGACGTGGAGCAAGCCTACGCCACAGGCAAAGCT
GCCGTGGAATATGCAATTGCCGGATACAATTCGGTGATGCCGACTATCGAACGCATCTCCAATTCGCCCTATACCTGGAA
AATCGGTATGGTTGAACTTTCCAAAGTTGCCAATGTAGAAAAAATGATGCCAGCAGACTTTATCAGTGAAGATGGCTTTG
GCATTACCGACAAATGCCGCGAATATCTCAGCCCTTTAATCGAGGGGGAAGACTATCCACCCTACAAGAATGGACTGCCC
GACTATATTCGGCTTAAAAATACGGCAGTTGCTAAAAAGCTGGCTGAGTTCAAAATTTAA

Upstream 100 bases:

>100_bases
ACCTGATCAGGCAGCTGGTTTTTCAAAGACTTCTGCTGCGTGACATTTATTTACACGATACGCGGACGAGAAACAGGTTT
TGATCAACCAGGAGTGGAGT

Downstream 100 bases:

>100_bases
TCTGTTTTGTTTTTTAGCAGTAAGAGCATATAAAATATGTGTTTAAGCTATATATGCTCAAGCTGTTCACGATTTTGATT
GTAGATTGATGCGGGGCTAT

Product: 6-phosphofructokinase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTIKNAFYAQSGGVTAVINASAAGLLETARAHPDKIGNVYAGRNGIIGALTEDLIDTGAEPLEAIRALRHTPSGAFGSCR
YKLKSLEDNRREYERLIKIFKAHNIGYFFYNGGGDSADTCLKVSQLADTLGYPIQAIHIPKTVDNDLPVTDCCPGFGSVA
KYVAVSMLEASFDVASMAKTSTKVFILEVMGRHAGWIAAAGGLASSKDRHVPIIILFPEVTFDEEKFLAKTDRYVKEYGY
CTVVVSEGVKGADGKFLSDQGLRDAFGHAQLGGVAPVIANMVRNGLGLKYHWGVSDYLQRAARHIASRTDVEQAYATGKA
AVEYAIAGYNSVMPTIERISNSPYTWKIGMVELSKVANVEKMMPADFISEDGFGITDKCREYLSPLIEGEDYPPYKNGLP
DYIRLKNTAVAKKLAEFKI

Sequences:

>Translated_419_residues
MTIKNAFYAQSGGVTAVINASAAGLLETARAHPDKIGNVYAGRNGIIGALTEDLIDTGAEPLEAIRALRHTPSGAFGSCR
YKLKSLEDNRREYERLIKIFKAHNIGYFFYNGGGDSADTCLKVSQLADTLGYPIQAIHIPKTVDNDLPVTDCCPGFGSVA
KYVAVSMLEASFDVASMAKTSTKVFILEVMGRHAGWIAAAGGLASSKDRHVPIIILFPEVTFDEEKFLAKTDRYVKEYGY
CTVVVSEGVKGADGKFLSDQGLRDAFGHAQLGGVAPVIANMVRNGLGLKYHWGVSDYLQRAARHIASRTDVEQAYATGKA
AVEYAIAGYNSVMPTIERISNSPYTWKIGMVELSKVANVEKMMPADFISEDGFGITDKCREYLSPLIEGEDYPPYKNGLP
DYIRLKNTAVAKKLAEFKI
>Mature_418_residues
TIKNAFYAQSGGVTAVINASAAGLLETARAHPDKIGNVYAGRNGIIGALTEDLIDTGAEPLEAIRALRHTPSGAFGSCRY
KLKSLEDNRREYERLIKIFKAHNIGYFFYNGGGDSADTCLKVSQLADTLGYPIQAIHIPKTVDNDLPVTDCCPGFGSVAK
YVAVSMLEASFDVASMAKTSTKVFILEVMGRHAGWIAAAGGLASSKDRHVPIIILFPEVTFDEEKFLAKTDRYVKEYGYC
TVVVSEGVKGADGKFLSDQGLRDAFGHAQLGGVAPVIANMVRNGLGLKYHWGVSDYLQRAARHIASRTDVEQAYATGKAA
VEYAIAGYNSVMPTIERISNSPYTWKIGMVELSKVANVEKMMPADFISEDGFGITDKCREYLSPLIEGEDYPPYKNGLPD
YIRLKNTAVAKKLAEFKI

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family [H]

Homologues:

None

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012003
- InterPro:   IPR012829
- InterPro:   IPR022953
- InterPro:   IPR015912
- InterPro:   IPR000023 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 45569; Mature: 45438

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKNAFYAQSGGVTAVINASAAGLLETARAHPDKIGNVYAGRNGIIGALTEDLIDTGAE
CCCCCCEEECCCCEEEEEECCHHHHHHHHHCCCHHHCCEECCCCCCHHHHHHHHHHCCCH
PLEAIRALRHTPSGAFGSCRYKLKSLEDNRREYERLIKIFKAHNIGYFFYNGGGDSADTC
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
LKVSQLADTLGYPIQAIHIPKTVDNDLPVTDCCPGFGSVAKYVAVSMLEASFDVASMAKT
HHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
STKVFILEVMGRHAGWIAAAGGLASSKDRHVPIIILFPEVTFDEEKFLAKTDRYVKEYGY
CCCEEEEEHHCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
CTVVVSEGVKGADGKFLSDQGLRDAFGHAQLGGVAPVIANMVRNGLGLKYHWGVSDYLQR
EEEEEECCCCCCCCCEECCCCCHHHHCCHHCCCHHHHHHHHHHHCCCEEEECCHHHHHHH
AARHIASRTDVEQAYATGKAAVEYAIAGYNSVMPTIERISNSPYTWKIGMVELSKVANVE
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
KMMPADFISEDGFGITDKCREYLSPLIEGEDYPPYKNGLPDYIRLKNTAVAKKLAEFKI
HHCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKNAFYAQSGGVTAVINASAAGLLETARAHPDKIGNVYAGRNGIIGALTEDLIDTGAE
CCCCCEEECCCCEEEEEECCHHHHHHHHHCCCHHHCCEECCCCCCHHHHHHHHHHCCCH
PLEAIRALRHTPSGAFGSCRYKLKSLEDNRREYERLIKIFKAHNIGYFFYNGGGDSADTC
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
LKVSQLADTLGYPIQAIHIPKTVDNDLPVTDCCPGFGSVAKYVAVSMLEASFDVASMAKT
HHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
STKVFILEVMGRHAGWIAAAGGLASSKDRHVPIIILFPEVTFDEEKFLAKTDRYVKEYGY
CCCEEEEEHHCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
CTVVVSEGVKGADGKFLSDQGLRDAFGHAQLGGVAPVIANMVRNGLGLKYHWGVSDYLQR
EEEEEECCCCCCCCCEECCCCCHHHHCCHHCCCHHHHHHHHHHHCCCEEEECCHHHHHHH
AARHIASRTDVEQAYATGKAAVEYAIAGYNSVMPTIERISNSPYTWKIGMVELSKVANVE
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
KMMPADFISEDGFGITDKCREYLSPLIEGEDYPPYKNGLPDYIRLKNTAVAKKLAEFKI
HHCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10913106 [H]