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The map label for this gene is argC

Identifier: 114330777

GI number: 114330777

Start: 780263

End: 781291

Strand: Direct

Name: argC

Synonym: Neut_0764

Alternate gene names: 114330777

Gene position: 780263-781291 (Clockwise)

Preceding gene: 114330776

Following gene: 114330778

Centisome position: 29.32

GC content: 46.16

Gene sequence:

>1029_bases
ATGATTAATGTTGGTATTGTAGGTGGGACAGGTTATACGGGTGTCGAGTTATTACGTATTCTCGCACAGCACCCGAAAGC
CAAGCTTAAAGTTATTACCTCTCGTCAAGAGGCTGGAACAGGAGTTGACGATCTTTTTTCCAGTTTGCGCGGACAGATTA
CGCTTAAATTCAGTGATCCGCTCAAGGTAGACTTTGGAAAATGTGATGTCGTCTTTTTCGCAACGCCAAATGGTATTGCC
ATGCAACAGGTAAGTGCATTACTTGGATCTGGAATAAAAGTTATTGATCTGTCTGCTGATTTCAGGATTAAAGACGTTGC
GGAATGGGAGGAATGGTATGGCATGTCGCACACAGCTCCTGAATTGGTGGCTGAAGCAGTCTATGGTTTACCCGAAGTTA
ACCGTGAAAAAATCAGGAATGCAAGATTGATTGCTAATCCCGGTTGCTATCCAACAGCGGTGCAGCTGGGTTTTATCCCG
CTGATCGAAGCAGGGGCCGTTGATGAGAATCATCTGATAGCCGATACCAAATCAGGTGTTTCCGGAGCAGGGCGCAAGGC
CGAAATACACACACTATATGCAGAAGCATCAGACAATTTCAAGTCTTATGCCGTAGCGGGTCACCGTCATTTACCTGAAA
TCAGACAAGGCTTATCCGAAAGATCAGGTAAGCCGATTGACCTGACTTTCGTGCCTCATCTAACCCCAATGATTCGGGGC
ATTCATGCCACATTGTATGCAAGACTGACCCGAGATGTTGATTTACAAGCTTTATATGAAAGCCGTTACGCTAATGAACC
CTTTGTTGATGTTCTTCCAGCAGGCAGCCATCCGGAAACACGTTCTGTACGTGGTTCAAATTTCTGCCGGATTGCAGTTC
ATCGTCCCCGGAATGGCGATACTGCGGTAATACTCTCGGTTACTGACAACTTGGTTAAAGGGGCTGCCGGACAGGCTGTT
CAAAATATGAATATTATGTATGGGCTGCCAGAGAAGATGGGCATTCAGCATATTCCGTTGCTACCCTAG

Upstream 100 bases:

>100_bases
CGCCCTCTTTGTTGGGCGGCTTTTTCGTATTGGGTTCACAACACAAGATACCGACTGCTTTTTGATAAAAAATTAATTTT
TTAGCTGTTGTTTCCTAGAG

Downstream 100 bases:

>100_bases
CAGTTTGTGATTAAAGAGTGAAGTGACTGAAAGAACGTCATATTGCAGATAATATATGCATAGTAATACCCTGGGAATTT
CTAAAGAATAAGGGAACGAA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MINVGIVGGTGYTGVELLRILAQHPKAKLKVITSRQEAGTGVDDLFSSLRGQITLKFSDPLKVDFGKCDVVFFATPNGIA
MQQVSALLGSGIKVIDLSADFRIKDVAEWEEWYGMSHTAPELVAEAVYGLPEVNREKIRNARLIANPGCYPTAVQLGFIP
LIEAGAVDENHLIADTKSGVSGAGRKAEIHTLYAEASDNFKSYAVAGHRHLPEIRQGLSERSGKPIDLTFVPHLTPMIRG
IHATLYARLTRDVDLQALYESRYANEPFVDVLPAGSHPETRSVRGSNFCRIAVHRPRNGDTAVILSVTDNLVKGAAGQAV
QNMNIMYGLPEKMGIQHIPLLP

Sequences:

>Translated_342_residues
MINVGIVGGTGYTGVELLRILAQHPKAKLKVITSRQEAGTGVDDLFSSLRGQITLKFSDPLKVDFGKCDVVFFATPNGIA
MQQVSALLGSGIKVIDLSADFRIKDVAEWEEWYGMSHTAPELVAEAVYGLPEVNREKIRNARLIANPGCYPTAVQLGFIP
LIEAGAVDENHLIADTKSGVSGAGRKAEIHTLYAEASDNFKSYAVAGHRHLPEIRQGLSERSGKPIDLTFVPHLTPMIRG
IHATLYARLTRDVDLQALYESRYANEPFVDVLPAGSHPETRSVRGSNFCRIAVHRPRNGDTAVILSVTDNLVKGAAGQAV
QNMNIMYGLPEKMGIQHIPLLP
>Mature_342_residues
MINVGIVGGTGYTGVELLRILAQHPKAKLKVITSRQEAGTGVDDLFSSLRGQITLKFSDPLKVDFGKCDVVFFATPNGIA
MQQVSALLGSGIKVIDLSADFRIKDVAEWEEWYGMSHTAPELVAEAVYGLPEVNREKIRNARLIANPGCYPTAVQLGFIP
LIEAGAVDENHLIADTKSGVSGAGRKAEIHTLYAEASDNFKSYAVAGHRHLPEIRQGLSERSGKPIDLTFVPHLTPMIRG
IHATLYARLTRDVDLQALYESRYANEPFVDVLPAGSHPETRSVRGSNFCRIAVHRPRNGDTAVILSVTDNLVKGAAGQAV
QNMNIMYGLPEKMGIQHIPLLP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=38.2608695652174, Blast_Score=202, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320913, Length=348, Percent_Identity=30.7471264367816, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_NITEC (Q0AHZ8)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746999.1
- ProteinModelPortal:   Q0AHZ8
- SMR:   Q0AHZ8
- STRING:   Q0AHZ8
- GeneID:   4272988
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0764
- NMPDR:   fig|335283.3.peg.2389
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- PhylomeDB:   Q0AHZ8
- ProtClustDB:   PRK00436
- BioCyc:   NEUT335283:NEUT_0764-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37172; Mature: 37172

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINVGIVGGTGYTGVELLRILAQHPKAKLKVITSRQEAGTGVDDLFSSLRGQITLKFSDP
CEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCHHCCCCHHHHHHHCCCEEEEEECCC
LKVDFGKCDVVFFATPNGIAMQQVSALLGSGIKVIDLSADFRIKDVAEWEEWYGMSHTAP
CEEECCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHCCCCCCHH
ELVAEAVYGLPEVNREKIRNARLIANPGCYPTAVQLGFIPLIEAGAVDENHLIADTKSGV
HHHHHHHHCCCCCCHHHHCCCEEEECCCCCHHHEEECCEEEEECCCCCCCCEEEECCCCC
SGAGRKAEIHTLYAEASDNFKSYAVAGHRHLPEIRQGLSERSGKPIDLTFVPHLTPMIRG
CCCCCCEEEEEEEECCCCCCHHEEECCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHH
IHATLYARLTRDVDLQALYESRYANEPFVDVLPAGSHPETRSVRGSNFCRIAVHRPRNGD
HHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCC
TAVILSVTDNLVKGAAGQAVQNMNIMYGLPEKMGIQHIPLLP
EEEEEEECHHHHHCCCCHHHHCCEEEEECCHHHCCCCCCCCC
>Mature Secondary Structure
MINVGIVGGTGYTGVELLRILAQHPKAKLKVITSRQEAGTGVDDLFSSLRGQITLKFSDP
CEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCHHCCCCHHHHHHHCCCEEEEEECCC
LKVDFGKCDVVFFATPNGIAMQQVSALLGSGIKVIDLSADFRIKDVAEWEEWYGMSHTAP
CEEECCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHCCCCCCHH
ELVAEAVYGLPEVNREKIRNARLIANPGCYPTAVQLGFIPLIEAGAVDENHLIADTKSGV
HHHHHHHHCCCCCCHHHHCCCEEEECCCCCHHHEEECCEEEEECCCCCCCCEEEECCCCC
SGAGRKAEIHTLYAEASDNFKSYAVAGHRHLPEIRQGLSERSGKPIDLTFVPHLTPMIRG
CCCCCCEEEEEEEECCCCCCHHEEECCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHH
IHATLYARLTRDVDLQALYESRYANEPFVDVLPAGSHPETRSVRGSNFCRIAVHRPRNGD
HHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCC
TAVILSVTDNLVKGAAGQAVQNMNIMYGLPEKMGIQHIPLLP
EEEEEEECHHHHHCCCCHHHHCCEEEEECCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA