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The map label for this gene is dacC [H]

Identifier: 114330774

GI number: 114330774

Start: 778027

End: 779169

Strand: Reverse

Name: dacC [H]

Synonym: Neut_0761

Alternate gene names: 114330774

Gene position: 779169-778027 (Counterclockwise)

Preceding gene: 114330780

Following gene: 114330773

Centisome position: 29.28

GC content: 48.12

Gene sequence:

>1143_bases
ATGAAGCTTTTGCTGACCCTCATGAAACAGTTTATCCTCTTCCTGTTCTTATTGATGCCCGTTTTTCCGGCATGGTCACA
ACAGCCGGAACTGTCAATTGCTGCCAAATCCTTTACTCTGACCGATTTTCACAGCGGCCAGACACTCGCCAGCTCCAACC
CGCATGAACGACTGGATCCTGCTTCGCTCACCAAGCTGATGACAGCCTACGTTGTCTTCTCCGCGCTGAAGCAGGAACGT
ATCAAGCTGGACCAGGTCGTGCCCGTATCCAAAAAAGCCTGGCGCATGGCAGGATCACGTATGTTTATCGAGCCAAACAA
ACCAGTAACTGTTGATGAGTTAATTCATGGGGTAATTGTACAATCAGGGAACGATGCCTGCGTTGCCCTAGCAGAGCTGA
TCGCCGGTTCAGAGGATCTGCTTGTGCACATGATGAATGAAGAAGCAAAACGCCTGGGCATGCACAACACGCATTTCACC
AACTCAACTGGTCTGACTCATCCTGATCACTACAGCACAGCTAATGATCTGGCATTATTGGCAGGCGCCATTATTAGGGA
TTTTCCAGAATACTACCCGCTCTACTCCTTACGCGAATATACCTACAACGGCATTACCCAGCAAAACCGTAACCGCCTTC
TATGGACGGATCCTAATGTTGACGGCATGAAAACAGGGTGGACGGAAGCTGCCGGATACTGCCTGGTTACCTCAGCAAAA
CGTGATCATCGGCGCCTTATCTCTGTAGTGATGGGTACCGCTTCACCTAATGCACGCAGCATTGAAAGCCAACGCCTGCT
AAATTATGGGTTCCAGTTTTTCGATACGGCACACCCTTACAAAAAGAACCAGCCGGTCGCAAATGTTCAAATCTGGAAAG
GCACACAAAATAAAATAAAAGTCGGCTTTAATCAGGATATCTATTTTTCACTCCCTAAAGGTAAGGTCGAAGGGGTAAAG
GCTCGAATGGAATATCGCCAGCCACTTATTGCACCCATTGATCAAGGCCAGGAAATAGGAAAGGTAAAATTTGTCCTGGA
TGGATTGGAAGTGGCCACTTACCCCCTGGTTGCTCTGGAAGCTGTTGATACAGCCAATTTCTTCGGGCGCGCATGGGATA
ATCTGAAAATGCTGTTCAACTAA

Upstream 100 bases:

>100_bases
TACAAGATAACCGTGAATTATGAGTTAGCGCATTAAGAATGTCAAATTTGCATCCAGGCAAGCTGGATTCAAGAAATACA
TGCTGCAAAGTCGGAGTATA

Downstream 100 bases:

>100_bases
TCTCGCGGACAATAAAAGCATGATTTATCTCAACGGAAAATTTCTACCAATAGAACAAGCTACGGTTCCGGTACTGGATA
GAGGTTTCATTTTTGGAGAT

Product: Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKLLLTLMKQFILFLFLLMPVFPAWSQQPELSIAAKSFTLTDFHSGQTLASSNPHERLDPASLTKLMTAYVVFSALKQER
IKLDQVVPVSKKAWRMAGSRMFIEPNKPVTVDELIHGVIVQSGNDACVALAELIAGSEDLLVHMMNEEAKRLGMHNTHFT
NSTGLTHPDHYSTANDLALLAGAIIRDFPEYYPLYSLREYTYNGITQQNRNRLLWTDPNVDGMKTGWTEAAGYCLVTSAK
RDHRRLISVVMGTASPNARSIESQRLLNYGFQFFDTAHPYKKNQPVANVQIWKGTQNKIKVGFNQDIYFSLPKGKVEGVK
ARMEYRQPLIAPIDQGQEIGKVKFVLDGLEVATYPLVALEAVDTANFFGRAWDNLKMLFN

Sequences:

>Translated_380_residues
MKLLLTLMKQFILFLFLLMPVFPAWSQQPELSIAAKSFTLTDFHSGQTLASSNPHERLDPASLTKLMTAYVVFSALKQER
IKLDQVVPVSKKAWRMAGSRMFIEPNKPVTVDELIHGVIVQSGNDACVALAELIAGSEDLLVHMMNEEAKRLGMHNTHFT
NSTGLTHPDHYSTANDLALLAGAIIRDFPEYYPLYSLREYTYNGITQQNRNRLLWTDPNVDGMKTGWTEAAGYCLVTSAK
RDHRRLISVVMGTASPNARSIESQRLLNYGFQFFDTAHPYKKNQPVANVQIWKGTQNKIKVGFNQDIYFSLPKGKVEGVK
ARMEYRQPLIAPIDQGQEIGKVKFVLDGLEVATYPLVALEAVDTANFFGRAWDNLKMLFN
>Mature_380_residues
MKLLLTLMKQFILFLFLLMPVFPAWSQQPELSIAAKSFTLTDFHSGQTLASSNPHERLDPASLTKLMTAYVVFSALKQER
IKLDQVVPVSKKAWRMAGSRMFIEPNKPVTVDELIHGVIVQSGNDACVALAELIAGSEDLLVHMMNEEAKRLGMHNTHFT
NSTGLTHPDHYSTANDLALLAGAIIRDFPEYYPLYSLREYTYNGITQQNRNRLLWTDPNVDGMKTGWTEAAGYCLVTSAK
RDHRRLISVVMGTASPNARSIESQRLLNYGFQFFDTAHPYKKNQPVANVQIWKGTQNKIKVGFNQDIYFSLPKGKVEGVK
ARMEYRQPLIAPIDQGQEIGKVKFVLDGLEVATYPLVALEAVDTANFFGRAWDNLKMLFN

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=376, Percent_Identity=44.1489361702128, Blast_Score=321, Evalue=5e-89,
Organism=Escherichia coli, GI1786851, Length=356, Percent_Identity=42.4157303370786, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI87082022, Length=373, Percent_Identity=42.627345844504, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI87082054, Length=258, Percent_Identity=31.7829457364341, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42820; Mature: 42820

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLTLMKQFILFLFLLMPVFPAWSQQPELSIAAKSFTLTDFHSGQTLASSNPHERLDP
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHCCCH
ASLTKLMTAYVVFSALKQERIKLDQVVPVSKKAWRMAGSRMFIEPNKPVTVDELIHGVIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHEE
QSGNDACVALAELIAGSEDLLVHMMNEEAKRLGMHNTHFTNSTGLTHPDHYSTANDLALL
ECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
AGAIIRDFPEYYPLYSLREYTYNGITQQNRNRLLWTDPNVDGMKTGWTEAAGYCLVTSAK
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHCCEEEEECCC
RDHRRLISVVMGTASPNARSIESQRLLNYGFQFFDTAHPYKKNQPVANVQIWKGTQNKIK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHCCCCCCCCCCCCCEEEEEECCCCEEE
VGFNQDIYFSLPKGKVEGVKARMEYRQPLIAPIDQGQEIGKVKFVLDGLEVATYPLVALE
ECCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHH
AVDTANFFGRAWDNLKMLFN
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLLLTLMKQFILFLFLLMPVFPAWSQQPELSIAAKSFTLTDFHSGQTLASSNPHERLDP
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHCCCH
ASLTKLMTAYVVFSALKQERIKLDQVVPVSKKAWRMAGSRMFIEPNKPVTVDELIHGVIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHEE
QSGNDACVALAELIAGSEDLLVHMMNEEAKRLGMHNTHFTNSTGLTHPDHYSTANDLALL
ECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
AGAIIRDFPEYYPLYSLREYTYNGITQQNRNRLLWTDPNVDGMKTGWTEAAGYCLVTSAK
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHCCEEEEECCC
RDHRRLISVVMGTASPNARSIESQRLLNYGFQFFDTAHPYKKNQPVANVQIWKGTQNKIK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHCCCCCCCCCCCCCEEEEEECCCCEEE
VGFNQDIYFSLPKGKVEGVKARMEYRQPLIAPIDQGQEIGKVKFVLDGLEVATYPLVALE
ECCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHH
AVDTANFFGRAWDNLKMLFN
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]