Click here to switch to the map view.

The map label for this gene is ycgR

Identifier: 114330762

GI number: 114330762

Start: 769273

End: 770082

Strand: Direct

Name: ycgR

Synonym: Neut_0749

Alternate gene names: 114330762

Gene position: 769273-770082 (Clockwise)

Preceding gene: 114330761

Following gene: 114330765

Centisome position: 28.91

GC content: 46.91

Gene sequence:

>810_bases
ATGGCCATACTCCAAACATTTTCCGAGCAGACGATCTCGTCAGCAAGAGCAAGCGATATAAAAGAGCCAGATTACAGCGT
GAATTCCCGGCCGGAAATATGTTTTTTTCTGAATGGGATCATGGAGGAAAAATCTCTGATTTCACTGTACCTTGCGCGGG
ACAGTCACTCCGCTATTCTCTCATCCATTCTGGCGGTTGATCCGCAGCAGAAGCTGTTGATAATGGATTACGGTATTAAT
GAAACACTCAATCAGATAGCGCTCAAAAGGGGATATCTGCGGTGTATTACCAGCCATAACCAGATCCGGATCGAGTTTGA
TTGCGATAATCTGCAACGTGTCCAGTTTGAGGGTCGTCATGCATTCAGTGCTGATATTCCGGAATCACTGAAACGTTTGC
AGCGGCGCAATTTTTACCGGGTCACTACGTCCATCACCAATCCTGCAGTTTGTACTATTCCTTTATTGCGGGCAGCAGAC
GAAGCGCCAGTTGTCTACAGCTTGCTGGATATCAGCTGTGGTGGCATGGCGTTGATAGATCAGCCAGATGCCGACACGCT
TCTGAAAGCTGGCACAACGCTTGAACACTGCCGGATTGATTTACCAGGAGACGGTAACTTGTTCAGTTCAATTGAAGCCT
CCATCCAGATCGCGTACGTCGGTACGGTTATTCTGAATAACGGGAATACCTGCCCGCGCATTGGTTGTGAATTTATCAAT
CTGCCCGAGAAATCAAGGCTATTGATACAGCGTTACATTACAAAACTGGAGCAGCAGGCAAGAAAACTTGAAACTGAATC
CGGTTTTTGA

Upstream 100 bases:

>100_bases
TCCATGATTCAGGTACGCAACCGGCTGGTAACGGCTTATCAGGAAATAATGAATATGCAAGTGTGAGATCCTGGGCTAAT
AAAGAACAAAGGGACAGACT

Downstream 100 bases:

>100_bases
AACCAGTGCCGCCGGTGTCATCAGGCGGGTGTTGTCACCATGCTGTTTTCCAGCTGATAGAGCCATGCCAGAAGCTCGGC
TATGGCTACGTATAACTCCG

Product: YcgR family protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MAILQTFSEQTISSARASDIKEPDYSVNSRPEICFFLNGIMEEKSLISLYLARDSHSAILSSILAVDPQQKLLIMDYGIN
ETLNQIALKRGYLRCITSHNQIRIEFDCDNLQRVQFEGRHAFSADIPESLKRLQRRNFYRVTTSITNPAVCTIPLLRAAD
EAPVVYSLLDISCGGMALIDQPDADTLLKAGTTLEHCRIDLPGDGNLFSSIEASIQIAYVGTVILNNGNTCPRIGCEFIN
LPEKSRLLIQRYITKLEQQARKLETESGF

Sequences:

>Translated_269_residues
MAILQTFSEQTISSARASDIKEPDYSVNSRPEICFFLNGIMEEKSLISLYLARDSHSAILSSILAVDPQQKLLIMDYGIN
ETLNQIALKRGYLRCITSHNQIRIEFDCDNLQRVQFEGRHAFSADIPESLKRLQRRNFYRVTTSITNPAVCTIPLLRAAD
EAPVVYSLLDISCGGMALIDQPDADTLLKAGTTLEHCRIDLPGDGNLFSSIEASIQIAYVGTVILNNGNTCPRIGCEFIN
LPEKSRLLIQRYITKLEQQARKLETESGF
>Mature_268_residues
AILQTFSEQTISSARASDIKEPDYSVNSRPEICFFLNGIMEEKSLISLYLARDSHSAILSSILAVDPQQKLLIMDYGINE
TLNQIALKRGYLRCITSHNQIRIEFDCDNLQRVQFEGRHAFSADIPESLKRLQRRNFYRVTTSITNPAVCTIPLLRAADE
APVVYSLLDISCGGMALIDQPDADTLLKAGTTLEHCRIDLPGDGNLFSSIEASIQIAYVGTVILNNGNTCPRIGCEFINL
PEKSRLLIQRYITKLEQQARKLETESGF

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain

Homologues:

Organism=Escherichia coli, GI1787443, Length=236, Percent_Identity=24.5762711864407, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCGR_NITEC (Q0AI13)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746984.1
- ProteinModelPortal:   Q0AI13
- STRING:   Q0AI13
- GeneID:   4273008
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0749
- NMPDR:   fig|335283.3.peg.2404
- eggNOG:   COG5581
- HOGENOM:   HBG135468
- OMA:   QLGFRFL
- PhylomeDB:   Q0AI13
- ProtClustDB:   CLSK586082
- BioCyc:   NEUT335283:NEUT_0749-MONOMER
- HAMAP:   MF_01457
- InterPro:   IPR009875
- InterPro:   IPR009926

Pfam domain/function: PF07238 PilZ; PF07317 YcgR

EC number: NA

Molecular weight: Translated: 30106; Mature: 29975

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILQTFSEQTISSARASDIKEPDYSVNSRPEICFFLNGIMEEKSLISLYLARDSHSAIL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHCHHHEEEEEEECCCHHHHH
SSILAVDPQQKLLIMDYGINETLNQIALKRGYLRCITSHNQIRIEFDCDNLQRVQFEGRH
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCEEEEECCCC
AFSADIPESLKRLQRRNFYRVTTSITNPAVCTIPLLRAADEAPVVYSLLDISCGGMALID
CCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEHHHHCCCCCCEEEEEECCCCCCEEEEC
QPDADTLLKAGTTLEHCRIDLPGDGNLFSSIEASIQIAYVGTVILNNGNTCPRIGCEFIN
CCCHHHHHHCCCCHHHEEEECCCCCCHHHHHHCEEEEEEEEEEEEECCCCCHHCCCCEEC
LPEKSRLLIQRYITKLEQQARKLETESGF
CCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AILQTFSEQTISSARASDIKEPDYSVNSRPEICFFLNGIMEEKSLISLYLARDSHSAIL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHCHHHEEEEEEECCCHHHHH
SSILAVDPQQKLLIMDYGINETLNQIALKRGYLRCITSHNQIRIEFDCDNLQRVQFEGRH
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCEEEEECCCC
AFSADIPESLKRLQRRNFYRVTTSITNPAVCTIPLLRAADEAPVVYSLLDISCGGMALID
CCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEHHHHCCCCCCEEEEEECCCCCCEEEEC
QPDADTLLKAGTTLEHCRIDLPGDGNLFSSIEASIQIAYVGTVILNNGNTCPRIGCEFIN
CCCHHHHHHCCCCHHHEEEECCCCCCHHHHHHCEEEEEEEEEEEEECCCCCHHCCCCEEC
LPEKSRLLIQRYITKLEQQARKLETESGF
CCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA