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The map label for this gene is atoS [H]

Identifier: 114330759

GI number: 114330759

Start: 766320

End: 767564

Strand: Direct

Name: atoS [H]

Synonym: Neut_0746

Alternate gene names: 114330759

Gene position: 766320-767564 (Clockwise)

Preceding gene: 114330752

Following gene: 114330760

Centisome position: 28.8

GC content: 51.65

Gene sequence:

>1245_bases
ATGAAAACAGAAGTTACTGCTACATCACTAGCCAACCATGAACAGCTCAGGCAGGCGTTTACTGTATTCAGCCAGGCCTC
CAGCCAGCTTTCCGGAATCTATCGCGAATTACAGCAGCAGGTTTCCCGGTTGACTGAAGAGCTGGCGCTGGCCAATGGAG
AATTGCAACGTGAGCTGGCTGCCAAGGAAGCACTTTCGCAACAGCTGGGTCAGTTGTTGACAGCACTGCCTGGTGGTGTT
GTTGTGCTGGATCATCAGGACCGTATCAGCCGGGTAAATCCGGCGGCAATTCGTTTTCTGGGAGAACCATTACTGGGGAT
AACGTGGCAGCGGATCGAGCAGGAACGTCTACAGCCAACTGCTCTGGCCGGGGAATGGTTGGCAGTAAAAACTGCTACTG
CCGCACCTGATTTATGCAGGATCTTTATCGAAAACAGCCTCTCGGAAACCACCAGAGAAAGTATTTTGCTGCTGCATGAC
ATCACAGAAGCCCATGCGCTACGCGAACAAAATCGCCGTAACCAGCGGCTGGCAGCAATGGGCGAGGTGGCTGCCGGCCT
GGCGCATCAGTTGCGCACACCTTTATCAACCGCATTGCTATATGCCGGACACTTGAGCGCTGAAACACTTGATGCTCAGG
AACGAAGCAGCTTTGCCGCTAAAACGATAGAGCGGCTCCATCATCTTGAGCATCTGATCCGTAACATGCTCCAGTTTGTA
AAAGGAGAGTCTGTGCCTGCGGGGAAAGTGAAATTATCTGTGCTGTTACGTAAATTACAGCAGGTGATGGCACCTCAGAT
GCAGCAACGTCAGCTTCGCTTCGTGGTGGAGGATAACAGCATGGGGTCCAGCCTGAATGTGAATCGGGATGCACTGAGTA
ATGCCGTAATGAATCTGCTTGATAACGCTGTGCAGATTGCACCTGCGGGCAGCCTGATCACGCTGATTTGTGAAACAACA
ATGAATGAAGCGAGACTGATTATCAGTGACGAAGGCCCGGGGATCGATCCGGTGTTACACGAACGGGTGTTTGAGCCGTT
TTTTACTACCCGGATAGAAGGAACCGGCCTGGGGCTGGCTATCGTGCATAACCTGATTCAGTCGATGCAGGGTGAAATCC
GGATTGATTCAACGCCTGGCATTGGAACCCGGTTTACGATCTGCCTGCCAAGAGCAGCAAAGGCACGAACCAATAAATTT
GTCCCGGCAGGTGAAATGGCAACAACTAAAAATGAGGACAGATAA

Upstream 100 bases:

>100_bases
GAATTCCGGAACAGAGAACATTTGTTTGTGCTATTCCAACCGTAATCCGGGTAGGGGGTGGTGCTAAGCTGAGCAACGTC
GAAATTGGGTTTGTTTTTCC

Downstream 100 bases:

>100_bases
AAGATGCAAAATTTGCCTGTACTGATTGTAGAAGATGATCCGGATTTGCTGGAAGCGTTGTGTGCAACCCTCAAATTGAA
GGGTTACACCAGTCTTGCCG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKTEVTATSLANHEQLRQAFTVFSQASSQLSGIYRELQQQVSRLTEELALANGELQRELAAKEALSQQLGQLLTALPGGV
VVLDHQDRISRVNPAAIRFLGEPLLGITWQRIEQERLQPTALAGEWLAVKTATAAPDLCRIFIENSLSETTRESILLLHD
ITEAHALREQNRRNQRLAAMGEVAAGLAHQLRTPLSTALLYAGHLSAETLDAQERSSFAAKTIERLHHLEHLIRNMLQFV
KGESVPAGKVKLSVLLRKLQQVMAPQMQQRQLRFVVEDNSMGSSLNVNRDALSNAVMNLLDNAVQIAPAGSLITLICETT
MNEARLIISDEGPGIDPVLHERVFEPFFTTRIEGTGLGLAIVHNLIQSMQGEIRIDSTPGIGTRFTICLPRAAKARTNKF
VPAGEMATTKNEDR

Sequences:

>Translated_414_residues
MKTEVTATSLANHEQLRQAFTVFSQASSQLSGIYRELQQQVSRLTEELALANGELQRELAAKEALSQQLGQLLTALPGGV
VVLDHQDRISRVNPAAIRFLGEPLLGITWQRIEQERLQPTALAGEWLAVKTATAAPDLCRIFIENSLSETTRESILLLHD
ITEAHALREQNRRNQRLAAMGEVAAGLAHQLRTPLSTALLYAGHLSAETLDAQERSSFAAKTIERLHHLEHLIRNMLQFV
KGESVPAGKVKLSVLLRKLQQVMAPQMQQRQLRFVVEDNSMGSSLNVNRDALSNAVMNLLDNAVQIAPAGSLITLICETT
MNEARLIISDEGPGIDPVLHERVFEPFFTTRIEGTGLGLAIVHNLIQSMQGEIRIDSTPGIGTRFTICLPRAAKARTNKF
VPAGEMATTKNEDR
>Mature_414_residues
MKTEVTATSLANHEQLRQAFTVFSQASSQLSGIYRELQQQVSRLTEELALANGELQRELAAKEALSQQLGQLLTALPGGV
VVLDHQDRISRVNPAAIRFLGEPLLGITWQRIEQERLQPTALAGEWLAVKTATAAPDLCRIFIENSLSETTRESILLLHD
ITEAHALREQNRRNQRLAAMGEVAAGLAHQLRTPLSTALLYAGHLSAETLDAQERSSFAAKTIERLHHLEHLIRNMLQFV
KGESVPAGKVKLSVLLRKLQQVMAPQMQQRQLRFVVEDNSMGSSLNVNRDALSNAVMNLLDNAVQIAPAGSLITLICETT
MNEARLIISDEGPGIDPVLHERVFEPFFTTRIEGTGLGLAIVHNLIQSMQGEIRIDSTPGIGTRFTICLPRAAKARTNKF
VPAGEMATTKNEDR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=30.0884955752212, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786600, Length=255, Percent_Identity=30.1960784313725, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790300, Length=345, Percent_Identity=27.2463768115942, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=30.6034482758621, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=221, Percent_Identity=28.0542986425339, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=30.3418803418803, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=219, Percent_Identity=26.4840182648402, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=27.9166666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=27.2373540856031, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=212, Percent_Identity=25, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=27.6315789473684, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45629; Mature: 45629

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEVTATSLANHEQLRQAFTVFSQASSQLSGIYRELQQQVSRLTEELALANGELQRELA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
AKEALSQQLGQLLTALPGGVVVLDHQDRISRVNPAAIRFLGEPLLGITWQRIEQERLQPT
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCH
ALAGEWLAVKTATAAPDLCRIFIENSLSETTRESILLLHDITEAHALREQNRRNQRLAAM
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
GEVAAGLAHQLRTPLSTALLYAGHLSAETLDAQERSSFAAKTIERLHHLEHLIRNMLQFV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGESVPAGKVKLSVLLRKLQQVMAPQMQQRQLRFVVEDNSMGSSLNVNRDALSNAVMNLL
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHH
DNAVQIAPAGSLITLICETTMNEARLIISDEGPGIDPVLHERVFEPFFTTRIEGTGLGLA
HHHHEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEECCCCCHHH
IVHNLIQSMQGEIRIDSTPGIGTRFTICLPRAAKARTNKFVPAGEMATTKNEDR
HHHHHHHHCCCCEEECCCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTEVTATSLANHEQLRQAFTVFSQASSQLSGIYRELQQQVSRLTEELALANGELQRELA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
AKEALSQQLGQLLTALPGGVVVLDHQDRISRVNPAAIRFLGEPLLGITWQRIEQERLQPT
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCH
ALAGEWLAVKTATAAPDLCRIFIENSLSETTRESILLLHDITEAHALREQNRRNQRLAAM
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
GEVAAGLAHQLRTPLSTALLYAGHLSAETLDAQERSSFAAKTIERLHHLEHLIRNMLQFV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGESVPAGKVKLSVLLRKLQQVMAPQMQQRQLRFVVEDNSMGSSLNVNRDALSNAVMNLL
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHH
DNAVQIAPAGSLITLICETTMNEARLIISDEGPGIDPVLHERVFEPFFTTRIEGTGLGLA
HHHHEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEECCCCCHHH
IVHNLIQSMQGEIRIDSTPGIGTRFTICLPRAAKARTNKFVPAGEMATTKNEDR
HHHHHHHHCCCCEEECCCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]