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The map label for this gene is fliI [H]

Identifier: 114330755

GI number: 114330755

Start: 761122

End: 762528

Strand: Reverse

Name: fliI [H]

Synonym: Neut_0742

Alternate gene names: 114330755

Gene position: 762528-761122 (Counterclockwise)

Preceding gene: 114330756

Following gene: 114330754

Centisome position: 28.66

GC content: 55.79

Gene sequence:

>1407_bases
ATGGACACCATCGGGCCGACACATACCTCGCTCTGGCGCGGCTTCATTCAGAATTGCCAACAACTGATTGAGCCTGTCAA
CCCTCTGCTCATCAGCGGTACACTGACCCGTGTAGCCGGATTGGTGATGGAGGCAGTCGGCCTCAAACTGGCAGTGGGGA
CCAGTTGTATTGTTTTTCTGCCAAATGGCACCAGTGTTACAGCGGAGGTAGTCGGCTTTTCCGGAGAACGGCTTTTCCTG
ATGCCATCCGGCGATATCTACGGGCTGACTCCCGGCGCAAAAGTAGTTCCAGTTGAATATACCGGTACACCTCCCCGCAT
CGGGGCGATACAGCATCCGCGACGACGTGCAGCTGACCGGGCAAAGCACATCAGTGTCGGCCCGGAACTGCTGGGGCGTG
TCCTGAACGGAGTCGGTGAACCACTTGATCGGCTCGGTCCGCTCCAGTGCGGGCACAACGTTCCACTTTATGGCCGTCCA
TTCAATCCACTGGAACGGGCACCCATCGAAAAAATACTGGATGTTGGCGTGCGTGCGATTAACACCCTGTTGAGCGTGGG
TCGTGGCCAGCGCATGGGATTGTTTGCCGGTAGTGGTGTGGGTAAAAGTGTCTTGCTCGGCATGATGGCGCGTTATACCA
GCGCGGATGTTATCGTGGTAGCACTGATCGGGGAACGGGGCCGGGAAGTGCAGGAATTCATCGAAACCATTCTGGGAGAG
GAAGGCCTGGCACGCTCAGTGGTCGTGGCTGCCCCGGCTGATACCTCACCACTAATGCGGTTGCATGGCGCTGCCTACGC
GACAGCGATAGCTGAATATTTCCGCGATGAAGGCAAGCATGTGCTGCTGATCATGGATTCACTCACCCGCTTTGCCATGG
CACAACGCGAGATTTCACTTGCCATTGGCGAACCGCCTGCCACTAAGGGTTATCCTCCCTCGGTATTTGCTCGCTTGCCC
CAACTGGTAGAACGCGCTGGCAATGGCCGACGGGGCAGTGGATCAATTACCGCCTTTTATACCGTGCTGGCCGAAAATGA
TGATCCAAACGATCCCATCGCTGATAATGCACGCGCCATTCTCGATGGTCACATTGTTCTTTCACGACACTTGGCCGACG
CCGGTCATTACCCGGCGATAGATATAGAGTCCTCGATCAGCCGGGTGATGGCCAGCTTGGTAACACGCGAGCAGCTTGGT
CAGGCGCAGCGTTTCAAGGCGCTGTACTCTCGCTACCAGCGCAGCCATGATCTGATCAGCGTTGGCGCATATATCAGTGG
CACTGATCCTCAACTGGATCAGGCTATCGCGCTTTATCCGGCACTCGAATCTTTCCTGCAGCAAGGCATGTTCGAGCAGG
AAAACTATGCCAAAAGCATGGACAAACTAACTACCCTGAATCTGTAA

Upstream 100 bases:

>100_bases
TGAAGTGGACGCCACACTGTCTACTCGCTGGCAACGCACCCTGGCCGCTCTCAGCCAGGATCCAGACTGGCTGACATAAC
GCTATCTGGCGGGCACCATC

Downstream 100 bases:

>100_bases
CCGGATAAGATGAATCATGGCCACTTCTCATTCACTCAAACTGTTACTGGAACATGCCCGTAAGCAGACGGATGATGCCG
CCATTAATCTGGGAAAGTTA

Product: flagellar protein export ATPase FliI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MDTIGPTHTSLWRGFIQNCQQLIEPVNPLLISGTLTRVAGLVMEAVGLKLAVGTSCIVFLPNGTSVTAEVVGFSGERLFL
MPSGDIYGLTPGAKVVPVEYTGTPPRIGAIQHPRRRAADRAKHISVGPELLGRVLNGVGEPLDRLGPLQCGHNVPLYGRP
FNPLERAPIEKILDVGVRAINTLLSVGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVALIGERGREVQEFIETILGE
EGLARSVVVAAPADTSPLMRLHGAAYATAIAEYFRDEGKHVLLIMDSLTRFAMAQREISLAIGEPPATKGYPPSVFARLP
QLVERAGNGRRGSGSITAFYTVLAENDDPNDPIADNARAILDGHIVLSRHLADAGHYPAIDIESSISRVMASLVTREQLG
QAQRFKALYSRYQRSHDLISVGAYISGTDPQLDQAIALYPALESFLQQGMFEQENYAKSMDKLTTLNL

Sequences:

>Translated_468_residues
MDTIGPTHTSLWRGFIQNCQQLIEPVNPLLISGTLTRVAGLVMEAVGLKLAVGTSCIVFLPNGTSVTAEVVGFSGERLFL
MPSGDIYGLTPGAKVVPVEYTGTPPRIGAIQHPRRRAADRAKHISVGPELLGRVLNGVGEPLDRLGPLQCGHNVPLYGRP
FNPLERAPIEKILDVGVRAINTLLSVGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVALIGERGREVQEFIETILGE
EGLARSVVVAAPADTSPLMRLHGAAYATAIAEYFRDEGKHVLLIMDSLTRFAMAQREISLAIGEPPATKGYPPSVFARLP
QLVERAGNGRRGSGSITAFYTVLAENDDPNDPIADNARAILDGHIVLSRHLADAGHYPAIDIESSISRVMASLVTREQLG
QAQRFKALYSRYQRSHDLISVGAYISGTDPQLDQAIALYPALESFLQQGMFEQENYAKSMDKLTTLNL
>Mature_468_residues
MDTIGPTHTSLWRGFIQNCQQLIEPVNPLLISGTLTRVAGLVMEAVGLKLAVGTSCIVFLPNGTSVTAEVVGFSGERLFL
MPSGDIYGLTPGAKVVPVEYTGTPPRIGAIQHPRRRAADRAKHISVGPELLGRVLNGVGEPLDRLGPLQCGHNVPLYGRP
FNPLERAPIEKILDVGVRAINTLLSVGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVALIGERGREVQEFIETILGE
EGLARSVVVAAPADTSPLMRLHGAAYATAIAEYFRDEGKHVLLIMDSLTRFAMAQREISLAIGEPPATKGYPPSVFARLP
QLVERAGNGRRGSGSITAFYTVLAENDDPNDPIADNARAILDGHIVLSRHLADAGHYPAIDIESSISRVMASLVTREQLG
QAQRFKALYSRYQRSHDLISVGAYISGTDPQLDQAIALYPALESFLQQGMFEQENYAKSMDKLTTLNL

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage [

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=358, Percent_Identity=31.5642458100559, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI50345984, Length=343, Percent_Identity=29.7376093294461, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4757810, Length=343, Percent_Identity=29.7376093294461, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI19913428, Length=426, Percent_Identity=27.6995305164319, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI19913426, Length=460, Percent_Identity=25.8695652173913, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI19913424, Length=244, Percent_Identity=32.3770491803279, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1788251, Length=434, Percent_Identity=63.594470046083, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1790170, Length=352, Percent_Identity=30.6818181818182, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790172, Length=296, Percent_Identity=28.7162162162162, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790217, Length=233, Percent_Identity=29.6137339055794, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144756, Length=309, Percent_Identity=32.0388349514563, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17570191, Length=457, Percent_Identity=26.0393873085339, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17510931, Length=359, Percent_Identity=28.4122562674095, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71988063, Length=342, Percent_Identity=28.9473684210526, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71988080, Length=342, Percent_Identity=28.9473684210526, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71988074, Length=328, Percent_Identity=28.0487804878049, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17565854, Length=233, Percent_Identity=33.0472103004292, Blast_Score=105, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6322581, Length=308, Percent_Identity=33.1168831168831, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319603, Length=465, Percent_Identity=27.3118279569892, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319370, Length=340, Percent_Identity=28.2352941176471, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6320016, Length=190, Percent_Identity=33.6842105263158, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24638766, Length=309, Percent_Identity=31.7152103559871, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24658560, Length=343, Percent_Identity=30.0291545189504, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281361666, Length=360, Percent_Identity=27.5, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24646341, Length=360, Percent_Identity=27.5, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17136796, Length=360, Percent_Identity=27.5, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28574560, Length=311, Percent_Identity=32.1543408360129, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI20129479, Length=319, Percent_Identity=28.2131661442006, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24583992, Length=244, Percent_Identity=32.3770491803279, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583988, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583986, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583984, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005714
- InterPro:   IPR020005 [H]

Pfam domain/function: PF00006 ATP-synt_ab [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50413; Mature: 50413

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIGPTHTSLWRGFIQNCQQLIEPVNPLLISGTLTRVAGLVMEAVGLKLAVGTSCIVFL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCEEEECCEEEEEE
PNGTSVTAEVVGFSGERLFLMPSGDIYGLTPGAKVVPVEYTGTPPRIGAIQHPRRRAADR
CCCCCEEEEEECCCCCEEEEEECCCEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHH
AKHISVGPELLGRVLNGVGEPLDRLGPLQCGHNVPLYGRPFNPLERAPIEKILDVGVRAI
HHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHH
NTLLSVGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVALIGERGREVQEFIETILGE
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCC
EGLARSVVVAAPADTSPLMRLHGAAYATAIAEYFRDEGKHVLLIMDSLTRFAMAQREISL
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHEE
AIGEPPATKGYPPSVFARLPQLVERAGNGRRGSGSITAFYTVLAENDDPNDPIADNARAI
EECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHH
LDGHIVLSRHLADAGHYPAIDIESSISRVMASLVTREQLGQAQRFKALYSRYQRSHDLIS
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VGAYISGTDPQLDQAIALYPALESFLQQGMFEQENYAKSMDKLTTLNL
ECCEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTIGPTHTSLWRGFIQNCQQLIEPVNPLLISGTLTRVAGLVMEAVGLKLAVGTSCIVFL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCEEEECCEEEEEE
PNGTSVTAEVVGFSGERLFLMPSGDIYGLTPGAKVVPVEYTGTPPRIGAIQHPRRRAADR
CCCCCEEEEEECCCCCEEEEEECCCEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHH
AKHISVGPELLGRVLNGVGEPLDRLGPLQCGHNVPLYGRPFNPLERAPIEKILDVGVRAI
HHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHH
NTLLSVGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVALIGERGREVQEFIETILGE
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCC
EGLARSVVVAAPADTSPLMRLHGAAYATAIAEYFRDEGKHVLLIMDSLTRFAMAQREISL
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHEE
AIGEPPATKGYPPSVFARLPQLVERAGNGRRGSGSITAFYTVLAENDDPNDPIADNARAI
EECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHH
LDGHIVLSRHLADAGHYPAIDIESSISRVMASLVTREQLGQAQRFKALYSRYQRSHDLIS
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VGAYISGTDPQLDQAIALYPALESFLQQGMFEQENYAKSMDKLTTLNL
ECCEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]