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The map label for this gene is mutT [C]

Identifier: 114330668

GI number: 114330668

Start: 663369

End: 664307

Strand: Reverse

Name: mutT [C]

Synonym: Neut_0653

Alternate gene names: 114330668

Gene position: 664307-663369 (Counterclockwise)

Preceding gene: 114330669

Following gene: 114330666

Centisome position: 24.96

GC content: 53.14

Gene sequence:

>939_bases
ATGCCCGACTTACCGTTGGTTGAAGTCGTCGTTGCCATTCTTATTCGTCCAGATAGCAGTTTCCTGCTCACTTGCCGGCC
AACTGGCAAGCCTTATTCTGGCTACTGGGAGTTTCCCGGGGGGAAAATAGAAACAGGAGAATCTCCTGTTCAGGCACTGG
CACGCGAACTGAATGAAGAACTGGGTATTACCCCCGACCAAGCCACGCCATGGCTGACACGGCTATTCAGTTACCCGCAT
GCCACGGTACAACTCAGATTTTATCGGGTAACCAGTTGGCAGGGTGAACCCGCTCCTCGTGAACAGCAGCAGCTCGCCTG
GCAAACCGCCGACAATGTCACTGTTTCTCCTTTGCTTCCGGCCAATATCCCCATTCTGCGCAGCCTGATGTTACCCTCGA
TCTATGCCATTACCTGTGCAGCTGAAACGGGTGTGGAAGCATCATTGTTATCCATCCGACAAGCTTTTCAGAGTGGCATA
AAACTTCTGCAAATCCGTGAAAAAGCTATGCCGCCCGATCAACTGGAATGCTATGTTCAGACTGTATTGCAACTTGCCCG
GAATAATCATCAGGTGACAGTACTGCTCAACGGGAATATCGCACTGGCGCAAACAGTGCAGGCTGATGGCATTCATCTGA
CTTCAACTCAATTGCTATCACTGACTGCCCGGCCAACTGTTAACTGGTGCGGTGCTTCCTGCCACAACGCAGAAGAACTC
AAGCGCGCTGAGCAGCTGGGCGTTGATTTTGTCACGCTGAGTCCCGTATACCCCACGCTCAGCCATCCGGGAGCTCCCTC
ACTGGGATGGGATAAGTTTTCTGTCCTCCTCCGGGATTACCCGCTGCCGGTTTATGCGTTAGGAGGATTACAGCCGACCG
ATCTGGCAATTGCCCAGGAACATGGCGCGCACGGCATTGCCATGATGCGCGGTATCTGA

Upstream 100 bases:

>100_bases
GCTGGCACGAGGTTCTCGCAATGGACGGGTTGCTCGCCAATTCGCCCGTGATTGGGCAGGTCAGCAAAAATTGGCAAAGG
CAGAATAGGGCAAAAATAAT

Downstream 100 bases:

>100_bases
TTTCTTCTGTCGGTGTTAACAAACTACACCAGATAAGTATCCACCCCGCTCAACAGCAAATCGTACTGAACTTCGACAAT
TTCCTTGATAACCTGTGCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPDLPLVEVVVAILIRPDSSFLLTCRPTGKPYSGYWEFPGGKIETGESPVQALARELNEELGITPDQATPWLTRLFSYPH
ATVQLRFYRVTSWQGEPAPREQQQLAWQTADNVTVSPLLPANIPILRSLMLPSIYAITCAAETGVEASLLSIRQAFQSGI
KLLQIREKAMPPDQLECYVQTVLQLARNNHQVTVLLNGNIALAQTVQADGIHLTSTQLLSLTARPTVNWCGASCHNAEEL
KRAEQLGVDFVTLSPVYPTLSHPGAPSLGWDKFSVLLRDYPLPVYALGGLQPTDLAIAQEHGAHGIAMMRGI

Sequences:

>Translated_312_residues
MPDLPLVEVVVAILIRPDSSFLLTCRPTGKPYSGYWEFPGGKIETGESPVQALARELNEELGITPDQATPWLTRLFSYPH
ATVQLRFYRVTSWQGEPAPREQQQLAWQTADNVTVSPLLPANIPILRSLMLPSIYAITCAAETGVEASLLSIRQAFQSGI
KLLQIREKAMPPDQLECYVQTVLQLARNNHQVTVLLNGNIALAQTVQADGIHLTSTQLLSLTARPTVNWCGASCHNAEEL
KRAEQLGVDFVTLSPVYPTLSHPGAPSLGWDKFSVLLRDYPLPVYALGGLQPTDLAIAQEHGAHGIAMMRGI
>Mature_311_residues
PDLPLVEVVVAILIRPDSSFLLTCRPTGKPYSGYWEFPGGKIETGESPVQALARELNEELGITPDQATPWLTRLFSYPHA
TVQLRFYRVTSWQGEPAPREQQQLAWQTADNVTVSPLLPANIPILRSLMLPSIYAITCAAETGVEASLLSIRQAFQSGIK
LLQIREKAMPPDQLECYVQTVLQLARNNHQVTVLLNGNIALAQTVQADGIHLTSTQLLSLTARPTVNWCGASCHNAEELK
RAEQLGVDFVTLSPVYPTLSHPGAPSLGWDKFSVLLRDYPLPVYALGGLQPTDLAIAQEHGAHGIAMMRGI

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

Organism=Escherichia coli, GI1786288, Length=123, Percent_Identity=34.1463414634146, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788056, Length=127, Percent_Identity=37.007874015748, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: 3.6.1.-; 2.5.1.3

Molecular weight: Translated: 34193; Mature: 34062

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLPLVEVVVAILIRPDSSFLLTCRPTGKPYSGYWEFPGGKIETGESPVQALARELNEE
CCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECCCCEEECCCHHHHHHHHHHHHH
LGITPDQATPWLTRLFSYPHATVQLRFYRVTSWQGEPAPREQQQLAWQTADNVTVSPLLP
HCCCCCCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEECCCCC
ANIPILRSLMLPSIYAITCAAETGVEASLLSIRQAFQSGIKLLQIREKAMPPDQLECYVQ
CCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TVLQLARNNHQVTVLLNGNIALAQTVQADGIHLTSTQLLSLTARPTVNWCGASCHNAEEL
HHHHHHHCCCEEEEEECCCEEEEEEECCCCEEEECHHEEEEECCCCCCCCCCCCCCHHHH
KRAEQLGVDFVTLSPVYPTLSHPGAPSLGWDKFSVLLRDYPLPVYALGGLQPTDLAIAQE
HHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
HGAHGIAMMRGI
CCCCCEEHCCCC
>Mature Secondary Structure 
PDLPLVEVVVAILIRPDSSFLLTCRPTGKPYSGYWEFPGGKIETGESPVQALARELNEE
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECCCCEEECCCHHHHHHHHHHHHH
LGITPDQATPWLTRLFSYPHATVQLRFYRVTSWQGEPAPREQQQLAWQTADNVTVSPLLP
HCCCCCCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEECCCCC
ANIPILRSLMLPSIYAITCAAETGVEASLLSIRQAFQSGIKLLQIREKAMPPDQLECYVQ
CCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TVLQLARNNHQVTVLLNGNIALAQTVQADGIHLTSTQLLSLTARPTVNWCGASCHNAEEL
HHHHHHHCCCEEEEEECCCEEEEEEECCCCEEEECHHEEEEECCCCCCCCCCCCCCHHHH
KRAEQLGVDFVTLSPVYPTLSHPGAPSLGWDKFSVLLRDYPLPVYALGGLQPTDLAIAQE
HHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
HGAHGIAMMRGI
CCCCCEEHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]