Click here to switch to the map view.

The map label for this gene is kup

Identifier: 114330541

GI number: 114330541

Start: 542901

End: 544826

Strand: Reverse

Name: kup

Synonym: Neut_0522

Alternate gene names: 114330541

Gene position: 544826-542901 (Counterclockwise)

Preceding gene: 114330542

Following gene: 114330540

Centisome position: 20.47

GC content: 54.05

Gene sequence:

>1926_bases
ATGGCACTCGATTCGGAATCATCTGCCAGTAACAGGCAAGGATCACGTAACGAGCAGGACACAAACCCCCGCCTCACTGC
TGCTTTATGCCTAACCGCCCTGGGTGTGGTCTACGGTGATATCGCTACCAGCCCTCTATATGCGTTTCGCGAAGCACTGC
ACAATATAGCGCCCGACTCAAGAACGCCTGAAAGTATCCTGGGTATCCTGTCGTTGATTTTCTGGGCGCTGATTATCCTC
GTTTCGATCAAGTATCTACTAATTATCATGCGCGCTGACAACCACGGCGAAGGCGGTATTCTGGCTCTGCTGGCACTGTT
GCGCCCCTGGCGCGGATCGCCACAACACCAGCGCAACGTACTGATTGTCCTTGGATTGTTTGGTGCGGCGCTGCTCTATG
GCGACGGCATGATCACACCAGCGATTTCGGTACTGAGTGCCATGGAAGGGCTGGAAGTGGCAGCACCACAACTGACATCC
TACATAATCCCGGCAACCACCGTTATTCTGGTGCTGCTGTTTATGGTACAGAAGCGAGGTACCGCGCGCATCGGCAGAGT
CTTCGGCCCGATCATGCTAGTGTGGTTTGTAGTAATCGCCTTGCTCGGATTGAATGGGATCATTCACCATCCGCAGGTGT
TGGTCGCGGTCAACCCCTATTATGGGATCAATTTCTTCACTGATAACGGCTGGAGCGCTTTCCGAGTTCTCGGTGGCGTG
TTTCTCGCCCTAACCGGCGCCGAGGCTCTCTATGCGGATATGGGACATGTTGGGCGAGCGCCGATCCGGCTAATGTGGTT
TGCCCTGGTACTGCCAGCCTTGTTACTTAATTATTTCGGGCAGGGGGCGCTACTATTGCTCGACCCACATGAGGCACAAC
CGTTTTTTCACCTAGCGCCGCCATCATTCCTATATTCCCTGGTAGGCCTGGCAACGCTCGCCACTATCATTGCCTCTCAG
GCGATCATTTCAGGTGTATTCTCGCTGACCCGGCAGGCGATTCAGCTTGGGCAGAGCCCACGGCTGACATTGGTGCAAAC
CTCCTCGGAGGAAATCGGCCAGGTCTACGTGCCTGCGGCAAACTGGTTCATGATGATTGCTGCCGTATGGCTGGTACTGC
ACTTCCGCTCCTCGGATAACCTCGCGGGTGCCTTTGGTATCGCGGTATCAGGTACTATGGTGATCACTACCATTCTGGCA
TTTTTTGTGATGCGCGAACGCTGGCACTGGAACATCCTGACCGCAGTAGCAGTGACGGTGGGGTTCCTGATAATTGACCT
GGCCTTCTTCAGTTCAAATCTACTCAAGATCACGGATGGTGGCTGGTTCCCGCTGGCCATAGCCGTGTTCATATTTACCT
TAATGATTACCTGGCAGCAGGGGCGCCAGCTTCTCATACAGAGAATACATAAGGAAACCGAGTCGTTCCAAGATTTTCTC
CAACGTATCGTGACTGATCCTCCTGTGCGTGTGTCTGGTACGGCAGTTTTCCTTACTATCCACCAGCACGATACACCGCC
GGCATTACTCTACCAGCTAATTCACAATAAGGCCTTGCACGAACAAGTGGTCCTGGTTACTGTAATTACCGAAGAGGTGC
CGCGTGTGCCGGCAGCAGAGCGCCTTGAAGTCATGGAGCTGTCTTCCGGTTTTCACCGCATCATTGTGCACTATGGATTC
ATGCAAAGTCCGAATGTTCCGGTGGCGCTGCGAGCATGTGAAACATTGGGATTGAAGATTGATCTCGACACCACGACCTA
TTATCTCAGCCGTGCCTCGTTGATCCCCACCGACGAACGCCCCGGAATGGCGCTCTGGCGAGATCGCCTGTTTGCATTTA
TGTCACGCAACAGCGCCTGGCCAACGGCGTTCTACCATCTGCCGCCAGAGCACGTGATCGAGCTCGGCATACAGGTCGAG
CTGTAA

Upstream 100 bases:

>100_bases
ATGCTTCGTCAAATATACTGCCGTTTACGGTTTACAGTAGGTTTGCATAATGGGTAGTTTAAGCAGTAATCTCCCTACAT
CGAAAAAAAGAAAATAAAAC

Downstream 100 bases:

>100_bases
CACGGTATTATTTAGCGCAATGCATCCGCTCCAGACGATAAAGCAGCAGGTAGTTGAGGTAGTTGCGGGAATGGATCCAG
GCAAGCAAATACGGCGATGT

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MALDSESSASNRQGSRNEQDTNPRLTAALCLTALGVVYGDIATSPLYAFREALHNIAPDSRTPESILGILSLIFWALIIL
VSIKYLLIIMRADNHGEGGILALLALLRPWRGSPQHQRNVLIVLGLFGAALLYGDGMITPAISVLSAMEGLEVAAPQLTS
YIIPATTVILVLLFMVQKRGTARIGRVFGPIMLVWFVVIALLGLNGIIHHPQVLVAVNPYYGINFFTDNGWSAFRVLGGV
FLALTGAEALYADMGHVGRAPIRLMWFALVLPALLLNYFGQGALLLLDPHEAQPFFHLAPPSFLYSLVGLATLATIIASQ
AIISGVFSLTRQAIQLGQSPRLTLVQTSSEEIGQVYVPAANWFMMIAAVWLVLHFRSSDNLAGAFGIAVSGTMVITTILA
FFVMRERWHWNILTAVAVTVGFLIIDLAFFSSNLLKITDGGWFPLAIAVFIFTLMITWQQGRQLLIQRIHKETESFQDFL
QRIVTDPPVRVSGTAVFLTIHQHDTPPALLYQLIHNKALHEQVVLVTVITEEVPRVPAAERLEVMELSSGFHRIIVHYGF
MQSPNVPVALRACETLGLKIDLDTTTYYLSRASLIPTDERPGMALWRDRLFAFMSRNSAWPTAFYHLPPEHVIELGIQVE
L

Sequences:

>Translated_641_residues
MALDSESSASNRQGSRNEQDTNPRLTAALCLTALGVVYGDIATSPLYAFREALHNIAPDSRTPESILGILSLIFWALIIL
VSIKYLLIIMRADNHGEGGILALLALLRPWRGSPQHQRNVLIVLGLFGAALLYGDGMITPAISVLSAMEGLEVAAPQLTS
YIIPATTVILVLLFMVQKRGTARIGRVFGPIMLVWFVVIALLGLNGIIHHPQVLVAVNPYYGINFFTDNGWSAFRVLGGV
FLALTGAEALYADMGHVGRAPIRLMWFALVLPALLLNYFGQGALLLLDPHEAQPFFHLAPPSFLYSLVGLATLATIIASQ
AIISGVFSLTRQAIQLGQSPRLTLVQTSSEEIGQVYVPAANWFMMIAAVWLVLHFRSSDNLAGAFGIAVSGTMVITTILA
FFVMRERWHWNILTAVAVTVGFLIIDLAFFSSNLLKITDGGWFPLAIAVFIFTLMITWQQGRQLLIQRIHKETESFQDFL
QRIVTDPPVRVSGTAVFLTIHQHDTPPALLYQLIHNKALHEQVVLVTVITEEVPRVPAAERLEVMELSSGFHRIIVHYGF
MQSPNVPVALRACETLGLKIDLDTTTYYLSRASLIPTDERPGMALWRDRLFAFMSRNSAWPTAFYHLPPEHVIELGIQVE
L
>Mature_640_residues
ALDSESSASNRQGSRNEQDTNPRLTAALCLTALGVVYGDIATSPLYAFREALHNIAPDSRTPESILGILSLIFWALIILV
SIKYLLIIMRADNHGEGGILALLALLRPWRGSPQHQRNVLIVLGLFGAALLYGDGMITPAISVLSAMEGLEVAAPQLTSY
IIPATTVILVLLFMVQKRGTARIGRVFGPIMLVWFVVIALLGLNGIIHHPQVLVAVNPYYGINFFTDNGWSAFRVLGGVF
LALTGAEALYADMGHVGRAPIRLMWFALVLPALLLNYFGQGALLLLDPHEAQPFFHLAPPSFLYSLVGLATLATIIASQA
IISGVFSLTRQAIQLGQSPRLTLVQTSSEEIGQVYVPAANWFMMIAAVWLVLHFRSSDNLAGAFGIAVSGTMVITTILAF
FVMRERWHWNILTAVAVTVGFLIIDLAFFSSNLLKITDGGWFPLAIAVFIFTLMITWQQGRQLLIQRIHKETESFQDFLQ
RIVTDPPVRVSGTAVFLTIHQHDTPPALLYQLIHNKALHEQVVLVTVITEEVPRVPAAERLEVMELSSGFHRIIVHYGFM
QSPNVPVALRACETLGLKIDLDTTTYYLSRASLIPTDERPGMALWRDRLFAFMSRNSAWPTAFYHLPPEHVIELGIQVEL

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=621, Percent_Identity=46.5378421900161, Blast_Score=569, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_NITEC (Q0AIM8)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746763.1
- STRING:   Q0AIM8
- GeneID:   4273788
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0522
- NMPDR:   fig|335283.3.peg.1399
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   ANSVKLF
- PhylomeDB:   Q0AIM8
- ProtClustDB:   CLSK763201
- BioCyc:   NEUT335283:NEUT_0522-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 70743; Mature: 70612

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12e121e4)-; HASH(0x12818aa8)-; HASH(0x128f3fcc)-; HASH(0x1142eec0)-; HASH(0x13349058)-; HASH(0x136addf8)-; HASH(0x136ab71c)-; HASH(0x13365bb4)-; HASH(0x135f07c8)-; HASH(0x12c2aff8)-; HASH(0x133d07f0)-; HASH(0x12ddaf14)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDSESSASNRQGSRNEQDTNPRLTAALCLTALGVVYGDIATSPLYAFREALHNIAPDS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
RTPESILGILSLIFWALIILVSIKYLLIIMRADNHGEGGILALLALLRPWRGSPQHQRNV
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCE
LIVLGLFGAALLYGDGMITPAISVLSAMEGLEVAAPQLTSYIIPATTVILVLLFMVQKRG
EEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TARIGRVFGPIMLVWFVVIALLGLNGIIHHPQVLVAVNPYYGINFFTDNGWSAFRVLGGV
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHH
FLALTGAEALYADMGHVGRAPIRLMWFALVLPALLLNYFGQGALLLLDPHEAQPFFHLAP
HHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECC
PSFLYSLVGLATLATIIASQAIISGVFSLTRQAIQLGQSPRLTLVQTSSEEIGQVYVPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHCCEEEECHH
NWFMMIAAVWLVLHFRSSDNLAGAFGIAVSGTMVITTILAFFVMRERWHWNILTAVAVTV
HHHHHHHHHHHHHHCCCCCCCCEEHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GFLIIDLAFFSSNLLKITDGGWFPLAIAVFIFTLMITWQQGRQLLIQRIHKETESFQDFL
HHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIVTDPPVRVSGTAVFLTIHQHDTPPALLYQLIHNKALHEQVVLVTVITEEVPRVPAAE
HHHHCCCCCEEECEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEEHHHCCCCCCHH
RLEVMELSSGFHRIIVHYGFMQSPNVPVALRACETLGLKIDLDTTTYYLSRASLIPTDER
HHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEHHHHCCCEEEECCHHHHHHHCCCCCCCCC
PGMALWRDRLFAFMSRNSAWPTAFYHLPPEHVIELGIQVEL
CCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCEEEH
>Mature Secondary Structure 
ALDSESSASNRQGSRNEQDTNPRLTAALCLTALGVVYGDIATSPLYAFREALHNIAPDS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
RTPESILGILSLIFWALIILVSIKYLLIIMRADNHGEGGILALLALLRPWRGSPQHQRNV
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCE
LIVLGLFGAALLYGDGMITPAISVLSAMEGLEVAAPQLTSYIIPATTVILVLLFMVQKRG
EEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TARIGRVFGPIMLVWFVVIALLGLNGIIHHPQVLVAVNPYYGINFFTDNGWSAFRVLGGV
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHH
FLALTGAEALYADMGHVGRAPIRLMWFALVLPALLLNYFGQGALLLLDPHEAQPFFHLAP
HHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECC
PSFLYSLVGLATLATIIASQAIISGVFSLTRQAIQLGQSPRLTLVQTSSEEIGQVYVPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHCCEEEECHH
NWFMMIAAVWLVLHFRSSDNLAGAFGIAVSGTMVITTILAFFVMRERWHWNILTAVAVTV
HHHHHHHHHHHHHHCCCCCCCCEEHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GFLIIDLAFFSSNLLKITDGGWFPLAIAVFIFTLMITWQQGRQLLIQRIHKETESFQDFL
HHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIVTDPPVRVSGTAVFLTIHQHDTPPALLYQLIHNKALHEQVVLVTVITEEVPRVPAAE
HHHHCCCCCEEECEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEEHHHCCCCCCHH
RLEVMELSSGFHRIIVHYGFMQSPNVPVALRACETLGLKIDLDTTTYYLSRASLIPTDER
HHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEHHHHCCCEEEECCHHHHHHHCCCCCCCCC
PGMALWRDRLFAFMSRNSAWPTAFYHLPPEHVIELGIQVEL
CCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCEEEH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA