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The map label for this gene is norB [H]

Identifier: 114330539

GI number: 114330539

Start: 540834

End: 542180

Strand: Reverse

Name: norB [H]

Synonym: Neut_0520

Alternate gene names: 114330539

Gene position: 542180-540834 (Counterclockwise)

Preceding gene: 114330540

Following gene: 114330538

Centisome position: 20.37

GC content: 49.0

Gene sequence:

>1347_bases
ATGAAATATTCGACCCAGAAGCTTGCTTACCCCTATTTCATCGCCGCATTAGCGCTGTTCCTTGTACAGGTATTGGCCGG
TGTCCTTGCCGGTTCCGTCTATACCTTGCCTAATTTACTGGCAGAAAGTTTGCCATTCCACATTATTCGGATGATTCACA
CCAATGCCCTGCTGATCTGGCTGCTGCTAGGTTACTTCGGGGCAGCTTATTTTCTGATTCCTGAAGAAAGCGAGCGAGAT
ATCCATAGCCCGAAAATTGCCTGGTTGCAATTGTTTATCTTCGTCTTCGCTGCACTGGCTGCCGTGGTGAGTTACCTGAT
GGGGATACATGAAGGCCGGGAGTTTCTGGAACAGCCTTTATGGGTCAAAGTGTTGTTAGTCGTTGCGTTCCTGTTATTTC
TGTACAACGTCTCTATGACAGTCCTCAAGGGACGAAAAACCGTTGTCTCCACAGTTCTGCTACTTGGCATGTGGGGGGCG
GCACTGTTATTTCTATTTGCCTTCTATAATCCGGATAACCTCGCACTGGACAAAATGTACTGGTGGTATGTCGTGCATCT
CTGGGTGGAAGGCATATGGGAGTTAATCATGGCATCGATGCTTGCTTTTTTGTTAATCAAGATGACTGGCGTGGACCGTG
AAGTCATCGAAAAATGGCTGTATGTGATTGTTGGTCTAGCGTTGTTCAGCGGATTGCTAGGCACCGGTCACCACTATTAC
TGGATTGGCACGCCAGGCTATTGGCAATGGATCGGCAGTCTGTTCTCGATTCTGGAAGTGCTGCCCTTCTTCGCTATGGT
GCTGTGGTGTTTCCACATGGTGTACCGCAGCGGACGCAATCATCCCAATAAGGCCGCCATGCTCTGGACCTTAGGCTGTC
CGGTGATGGCTTTTTTCGGTGCCGGGGTATGGGGGCTAATGCACAGTTTCTCATTCATAAATTTTTACAGTCATGGTACG
CAAATCACCGCTGCTCACGGACACATGGCATTTTATGGTGCCTACGTCATGCTCAATCTGGCTTTCTTCACTTACGCCCT
GCCACAATTGCGCAGCGTGCAACCATATAACCAGGTTTTGAATATGTGGGGTTTCTGGGTGATGACTGCTTCCATGGCGT
TCATGACTTTTACGCTGACCTTTGCCGGGGTGCTGCAAACCCATTTACAACGCGTGGTCGGTATGGGGTTCATGGAAATT
CAGCAGCAACTGGATTTATTCTACTGGATGCGGTTGTTGTCCGGTATCGTCTTTGTTGCCGGTGCAATCCTGTACATCTA
CGCCGCATTAGGACCTACCAAAAATCAGGTGTCATCTTCGCCGAACTTGCAACCAACCCACAAATGA

Upstream 100 bases:

>100_bases
CGATTTTCTTGAGTGGGTCAGTCGTATTGATACACAAGGATGGCCTCCAAATACCGCAGGCTAACTCACCTGAACAACTA
TCATACGAAGGAAAATATCC

Downstream 100 bases:

>100_bases
AACAGTTGCTCGCTACTCCTGGAATATATTCGTGACATCCACAACGACAGACCTGCCATTTTATGTTCCAGTCGGCAATG
AGTGCGAACTGTTTGGAGTC

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: NOR large subunit; Nitric oxide reductase cytochrome b subunit [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKYSTQKLAYPYFIAALALFLVQVLAGVLAGSVYTLPNLLAESLPFHIIRMIHTNALLIWLLLGYFGAAYFLIPEESERD
IHSPKIAWLQLFIFVFAALAAVVSYLMGIHEGREFLEQPLWVKVLLVVAFLLFLYNVSMTVLKGRKTVVSTVLLLGMWGA
ALLFLFAFYNPDNLALDKMYWWYVVHLWVEGIWELIMASMLAFLLIKMTGVDREVIEKWLYVIVGLALFSGLLGTGHHYY
WIGTPGYWQWIGSLFSILEVLPFFAMVLWCFHMVYRSGRNHPNKAAMLWTLGCPVMAFFGAGVWGLMHSFSFINFYSHGT
QITAAHGHMAFYGAYVMLNLAFFTYALPQLRSVQPYNQVLNMWGFWVMTASMAFMTFTLTFAGVLQTHLQRVVGMGFMEI
QQQLDLFYWMRLLSGIVFVAGAILYIYAALGPTKNQVSSSPNLQPTHK

Sequences:

>Translated_448_residues
MKYSTQKLAYPYFIAALALFLVQVLAGVLAGSVYTLPNLLAESLPFHIIRMIHTNALLIWLLLGYFGAAYFLIPEESERD
IHSPKIAWLQLFIFVFAALAAVVSYLMGIHEGREFLEQPLWVKVLLVVAFLLFLYNVSMTVLKGRKTVVSTVLLLGMWGA
ALLFLFAFYNPDNLALDKMYWWYVVHLWVEGIWELIMASMLAFLLIKMTGVDREVIEKWLYVIVGLALFSGLLGTGHHYY
WIGTPGYWQWIGSLFSILEVLPFFAMVLWCFHMVYRSGRNHPNKAAMLWTLGCPVMAFFGAGVWGLMHSFSFINFYSHGT
QITAAHGHMAFYGAYVMLNLAFFTYALPQLRSVQPYNQVLNMWGFWVMTASMAFMTFTLTFAGVLQTHLQRVVGMGFMEI
QQQLDLFYWMRLLSGIVFVAGAILYIYAALGPTKNQVSSSPNLQPTHK
>Mature_448_residues
MKYSTQKLAYPYFIAALALFLVQVLAGVLAGSVYTLPNLLAESLPFHIIRMIHTNALLIWLLLGYFGAAYFLIPEESERD
IHSPKIAWLQLFIFVFAALAAVVSYLMGIHEGREFLEQPLWVKVLLVVAFLLFLYNVSMTVLKGRKTVVSTVLLLGMWGA
ALLFLFAFYNPDNLALDKMYWWYVVHLWVEGIWELIMASMLAFLLIKMTGVDREVIEKWLYVIVGLALFSGLLGTGHHYY
WIGTPGYWQWIGSLFSILEVLPFFAMVLWCFHMVYRSGRNHPNKAAMLWTLGCPVMAFFGAGVWGLMHSFSFINFYSHGT
QITAAHGHMAFYGAYVMLNLAFFTYALPQLRSVQPYNQVLNMWGFWVMTASMAFMTFTLTFAGVLQTHLQRVVGMGFMEI
QQQLDLFYWMRLLSGIVFVAGAILYIYAALGPTKNQVSSSPNLQPTHK

Specific function: Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen red

COG id: COG3256

COG function: function code P; Nitric oxide reductase large subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.7.99.7 [H]

Molecular weight: Translated: 51072; Mature: 51072

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSTQKLAYPYFIAALALFLVQVLAGVLAGSVYTLPNLLAESLPFHIIRMIHTNALLIW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLGYFGAAYFLIPEESERDIHSPKIAWLQLFIFVFAALAAVVSYLMGIHEGREFLEQPL
HHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
WVKVLLVVAFLLFLYNVSMTVLKGRKTVVSTVLLLGMWGAALLFLFAFYNPDNLALDKMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
WWYVVHLWVEGIWELIMASMLAFLLIKMTGVDREVIEKWLYVIVGLALFSGLLGTGHHYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
WIGTPGYWQWIGSLFSILEVLPFFAMVLWCFHMVYRSGRNHPNKAAMLWTLGCPVMAFFG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHH
AGVWGLMHSFSFINFYSHGTQITAAHGHMAFYGAYVMLNLAFFTYALPQLRSVQPYNQVL
CHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NMWGFWVMTASMAFMTFTLTFAGVLQTHLQRVVGMGFMEIQQQLDLFYWMRLLSGIVFVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAILYIYAALGPTKNQVSSSPNLQPTHK
HHHHHHHHHCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKYSTQKLAYPYFIAALALFLVQVLAGVLAGSVYTLPNLLAESLPFHIIRMIHTNALLIW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLGYFGAAYFLIPEESERDIHSPKIAWLQLFIFVFAALAAVVSYLMGIHEGREFLEQPL
HHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
WVKVLLVVAFLLFLYNVSMTVLKGRKTVVSTVLLLGMWGAALLFLFAFYNPDNLALDKMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
WWYVVHLWVEGIWELIMASMLAFLLIKMTGVDREVIEKWLYVIVGLALFSGLLGTGHHYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
WIGTPGYWQWIGSLFSILEVLPFFAMVLWCFHMVYRSGRNHPNKAAMLWTLGCPVMAFFG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHH
AGVWGLMHSFSFINFYSHGTQITAAHGHMAFYGAYVMLNLAFFTYALPQLRSVQPYNQVL
CHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NMWGFWVMTASMAFMTFTLTFAGVLQTHLQRVVGMGFMEIQQQLDLFYWMRLLSGIVFVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAILYIYAALGPTKNQVSSSPNLQPTHK
HHHHHHHHHCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7508388; 2542222; 9521721 [H]