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The map label for this gene is czcB [H]

Identifier: 114330497

GI number: 114330497

Start: 490856

End: 492352

Strand: Direct

Name: czcB [H]

Synonym: Neut_0477

Alternate gene names: 114330497

Gene position: 490856-492352 (Clockwise)

Preceding gene: 114330496

Following gene: 114330498

Centisome position: 18.45

GC content: 50.97

Gene sequence:

>1497_bases
ATGAACGTTAGCGGACGATTACCCATTGTGGCAGTTATTCTGGTTGGCATTTTGCTAGGGGCGTTGCTTTTGATCCAGGA
TAAATTCAGGCTGCCGGATGCTGAAGAGTCATCTCATTCTTTTGCAGGGACAACTGAACATCAATCAACAATCGGACCGA
AGGGCGGGGAGCTGTTCTCGGAAGATGATTTAAGCCTTGAGTTGACTATTCATGAGAGTGGCACGTTTCCACAATTCAGG
CTCTATCCATATCGACAGAAACAACCACTGGCACCGACTGAAGTAAAGGTAACGATTGTATTGTCCCGTCTTGGCAGGCC
GGCGCAACTGTTTCACTTCAGGCCGGAAAGTGACTATCTGGTTAGCGATCAGGAAGTGGGAGAACCTCATTCTTTCGAGC
TGATCATTGTCGCTGAATATCAGGGCAAGACCTATCGCTGGCATCACAGCGAGGTTGAGGCGCGTGTAGAAATGTCCGAT
ACGGCGATGCAAAGCAACGGTATTGAACTGGCCACAGCTGGTCCTGCCGCCATTCACTCTAAAATTACGCTGCCGGGCGA
AATTATTTTCAATGAACATCATATCGTGCATGTCGTGCCGCGTTTGCCCGGCATGGTGGTGTCGATTAAACGCCATCACG
GACAAAGAGTGAAAAAGGGAGAGGTACTTGCGATCATGGAAAGTGCCATGCTGGCCGATTTGCGCAGTCAATACCTGCTT
GCCCGCAAGCGCTTGGTGCTGGCACAAACAATTTATGATCGGGAAGAGCAGTTGTGGCGGGAAAAAATCACAGCAAAACA
GGATTACCTTGTGGCACAACAGCAACGGGAAGAAGCCAGCATAGCAACCCAGCTGGCAGCCGAGCGCTTGCGAGCGCTGG
GCGTACAACCAGAATCCGGGTTGTCTTGGGAAAATATTGCGCATTATAAAATCCGTTCTCCTATTTCCGGGATTGTCATT
GATGAAGCAATTGTTACAGGAGAGGTCGTCAAGGAGGATAAGACTGCGTATATCGTTGCTGACATTTCCACAGTCTGGGC
GGCTGTCAGGGTATTCCCCCGGAATCTGCATCAGGTTCACATAGGTCAGCAGGCTGTCATCCGGGCAAATGCCTATGATT
TGACGCGGGAAGGTAAGGTAATTTACGTGACGACACTGCTTGACGAGCAAACACGCACAGCTATTGCCCGGGTGCAGCTC
GATAATCGGGATGAACAATGGCGCCCTGGCATGTTCGTCAAGGCCGATTTGCAGACCGAAGCAGTCGAAGTCCCGGTGGC
GGTGTCGCTGGAAGCGATACAGACACTGAATGACCAGTCGGTAGTGTTTGGTCGCTACGGAGAGTATTTCGAAATGCGTC
CGCTCAAACTAGGCCGCAGCGATAGCCAGATGGCTGAGGTAGTCGAAGGCTTGTTTGCAGGCGAAGACTACGCAGCGAGT
AACAGCTTCATCATTAAATCAGAGCTGGGGAAGGCTGGAGCAGTACATGAGCATTGA

Upstream 100 bases:

>100_bases
AACGTCTGGTCAATATCATCGAGCAGTTGATTGCAGCACCGCTTGCTGATTCAGCTGCAGATTACACAAAGCTCAATACT
CAAGGGAAGGAGCGTAATCA

Downstream 100 bases:

>100_bases
GGAAACATGGGTTGATCGTCTGCGTAACCGGGCCATATTGCCTGTTTTCTGTTTTATCTTGTTTTTGGCGGCAACATTGA
GCGGAGATACTACTCATGTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MNVSGRLPIVAVILVGILLGALLLIQDKFRLPDAEESSHSFAGTTEHQSTIGPKGGELFSEDDLSLELTIHESGTFPQFR
LYPYRQKQPLAPTEVKVTIVLSRLGRPAQLFHFRPESDYLVSDQEVGEPHSFELIIVAEYQGKTYRWHHSEVEARVEMSD
TAMQSNGIELATAGPAAIHSKITLPGEIIFNEHHIVHVVPRLPGMVVSIKRHHGQRVKKGEVLAIMESAMLADLRSQYLL
ARKRLVLAQTIYDREEQLWREKITAKQDYLVAQQQREEASIATQLAAERLRALGVQPESGLSWENIAHYKIRSPISGIVI
DEAIVTGEVVKEDKTAYIVADISTVWAAVRVFPRNLHQVHIGQQAVIRANAYDLTREGKVIYVTTLLDEQTRTAIARVQL
DNRDEQWRPGMFVKADLQTEAVEVPVAVSLEAIQTLNDQSVVFGRYGEYFEMRPLKLGRSDSQMAEVVEGLFAGEDYAAS
NSFIIKSELGKAGAVHEH

Sequences:

>Translated_498_residues
MNVSGRLPIVAVILVGILLGALLLIQDKFRLPDAEESSHSFAGTTEHQSTIGPKGGELFSEDDLSLELTIHESGTFPQFR
LYPYRQKQPLAPTEVKVTIVLSRLGRPAQLFHFRPESDYLVSDQEVGEPHSFELIIVAEYQGKTYRWHHSEVEARVEMSD
TAMQSNGIELATAGPAAIHSKITLPGEIIFNEHHIVHVVPRLPGMVVSIKRHHGQRVKKGEVLAIMESAMLADLRSQYLL
ARKRLVLAQTIYDREEQLWREKITAKQDYLVAQQQREEASIATQLAAERLRALGVQPESGLSWENIAHYKIRSPISGIVI
DEAIVTGEVVKEDKTAYIVADISTVWAAVRVFPRNLHQVHIGQQAVIRANAYDLTREGKVIYVTTLLDEQTRTAIARVQL
DNRDEQWRPGMFVKADLQTEAVEVPVAVSLEAIQTLNDQSVVFGRYGEYFEMRPLKLGRSDSQMAEVVEGLFAGEDYAAS
NSFIIKSELGKAGAVHEH
>Mature_498_residues
MNVSGRLPIVAVILVGILLGALLLIQDKFRLPDAEESSHSFAGTTEHQSTIGPKGGELFSEDDLSLELTIHESGTFPQFR
LYPYRQKQPLAPTEVKVTIVLSRLGRPAQLFHFRPESDYLVSDQEVGEPHSFELIIVAEYQGKTYRWHHSEVEARVEMSD
TAMQSNGIELATAGPAAIHSKITLPGEIIFNEHHIVHVVPRLPGMVVSIKRHHGQRVKKGEVLAIMESAMLADLRSQYLL
ARKRLVLAQTIYDREEQLWREKITAKQDYLVAQQQREEASIATQLAAERLRALGVQPESGLSWENIAHYKIRSPISGIVI
DEAIVTGEVVKEDKTAYIVADISTVWAAVRVFPRNLHQVHIGQQAVIRANAYDLTREGKVIYVTTLLDEQTRTAIARVQL
DNRDEQWRPGMFVKADLQTEAVEVPVAVSLEAIQTLNDQSVVFGRYGEYFEMRPLKLGRSDSQMAEVVEGLFAGEDYAAS
NSFIIKSELGKAGAVHEH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 55719; Mature: 55719

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSGRLPIVAVILVGILLGALLLIQDKFRLPDAEESSHSFAGTTEHQSTIGPKGGELFS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EDDLSLELTIHESGTFPQFRLYPYRQKQPLAPTEVKVTIVLSRLGRPAQLFHFRPESDYL
CCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCE
VSDQEVGEPHSFELIIVAEYQGKTYRWHHSEVEARVEMSDTAMQSNGIELATAGPAAIHS
ECCHHCCCCCCEEEEEEEECCCCEEEEECCHHEEEEEEHHHHHHCCCEEEEECCCHHHCC
KITLPGEIIFNEHHIVHVVPRLPGMVVSIKRHHGQRVKKGEVLAIMESAMLADLRSQYLL
EEECCCEEEECCCEEEEEECCCCCEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ARKRLVLAQTIYDREEQLWREKITAKQDYLVAQQQREEASIATQLAAERLRALGVQPESG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LSWENIAHYKIRSPISGIVIDEAIVTGEVVKEDKTAYIVADISTVWAAVRVFPRNLHQVH
CCHHHEEEEEECCCCCCEEEEHHHHCCHHHCCCCCEEEEEEHHHHHHHHHHHHCCCEEEE
IGQQAVIRANAYDLTREGKVIYVTTLLDEQTRTAIARVQLDNRDEQWRPGMFVKADLQTE
CCCEEEEEECCEEECCCCCEEEEEEECCCHHHHEEEEEEECCCCCCCCCCEEEEECCCCC
AVEVPVAVSLEAIQTLNDQSVVFGRYGEYFEMRPLKLGRSDSQMAEVVEGLFAGEDYAAS
EEECCEEEEHHHHHHCCCCEEEEECCCCEEEECCEECCCCHHHHHHHHHHHHCCCCCCCC
NSFIIKSELGKAGAVHEH
CCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MNVSGRLPIVAVILVGILLGALLLIQDKFRLPDAEESSHSFAGTTEHQSTIGPKGGELFS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EDDLSLELTIHESGTFPQFRLYPYRQKQPLAPTEVKVTIVLSRLGRPAQLFHFRPESDYL
CCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCE
VSDQEVGEPHSFELIIVAEYQGKTYRWHHSEVEARVEMSDTAMQSNGIELATAGPAAIHS
ECCHHCCCCCCEEEEEEEECCCCEEEEECCHHEEEEEEHHHHHHCCCEEEEECCCHHHCC
KITLPGEIIFNEHHIVHVVPRLPGMVVSIKRHHGQRVKKGEVLAIMESAMLADLRSQYLL
EEECCCEEEECCCEEEEEECCCCCEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ARKRLVLAQTIYDREEQLWREKITAKQDYLVAQQQREEASIATQLAAERLRALGVQPESG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LSWENIAHYKIRSPISGIVIDEAIVTGEVVKEDKTAYIVADISTVWAAVRVFPRNLHQVH
CCHHHEEEEEECCCCCCEEEEHHHHCCHHHCCCCCEEEEEEHHHHHHHHHHHHCCCEEEE
IGQQAVIRANAYDLTREGKVIYVTTLLDEQTRTAIARVQLDNRDEQWRPGMFVKADLQTE
CCCEEEEEECCEEECCCCCEEEEEEECCCHHHHEEEEEEECCCCCCCCCCEEEEECCCCC
AVEVPVAVSLEAIQTLNDQSVVFGRYGEYFEMRPLKLGRSDSQMAEVVEGLFAGEDYAAS
EEECCEEEEHHHHHHCCCCEEEEECCCCEEEECCEECCCCHHHHHHHHHHHHCCCCCCCC
NSFIIKSELGKAGAVHEH
CCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]