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The map label for this gene is czcC [H]

Identifier: 114330496

GI number: 114330496

Start: 489435

End: 490859

Strand: Direct

Name: czcC [H]

Synonym: Neut_0476

Alternate gene names: 114330496

Gene position: 489435-490859 (Clockwise)

Preceding gene: 114330495

Following gene: 114330497

Centisome position: 18.39

GC content: 47.65

Gene sequence:

>1425_bases
GTGATATCCGGTGTGTACTTACGGCATGACTGTTCATGGGGAATCATCGTGATTGAGTATCAGACAGCGAAGGCAATATT
GCGACAACTTCGTACAAGGCAGATGGTGCTGGTCTTTGCATCATTCTTTGCGGGAATTATACCTATCTTGGGGCATGGTA
TGGCTTATGCCGATACTCATCCAGTCATCAATATATCGGCTGAGAAAGGTGAGGATCTGACCTTGCGTCAGGCGTTGCAG
CAGGTTTTGCAGAATAATCCTGAACTGGCAGCTTTTTCCAGAGAAGTGGCTGCTTATGAAGGGACAAAATTACAGGCCGG
TTTGCTGAAAAATCCTGAATTCAGTGTTGGGGCAGAAAGTATTGATTCCTCTAACCCGAATATAGAAAGGTTTACAACTT
TCCGTATCAGTCAGTTGATTGAGCTTGGTGGTAAGCGATCTGCCCGGGTGAATGTGGCAACACTGGGGCAGGAGCTGGCC
GATCAGGCTTATGCTGCCAAACGGTTGGAAGTTGTTGCCCGTACTGCTAATGCTTTTATTGATGTGCTGGAAAATCAGGT
GCATGTAAGCGTGATGGACGACACTTTGCGTCTGATGCAAAAGGCAATGAAAACAGTTGTGAAACGGGTCGAAGCGGGGA
AAGCGCCGCCTATTGAAGCTACTCGTTCAAAGGTAGCATTATCCGCTGCGAGTATTGAACTGGAACAGGGTAGGCGCAAT
TTGTCAGCGGCGCGGGCAAAGTTGGCGCTTCTCTGGGGGGAGGCGGAGCCGCGCTTCGGCCAGGCCTTGGGAGAACTGGA
ATCATTTGTTGAGATACCGGAATTTGATCAGCTGGTAAAACGCCTTGAAGAAAACCCGATTATGCTGCAAAGCCTTAAAA
ATATCGCGCAGCGTGAGGCGATGGTCGAGTTGCAAAAAGCGAATAAAATTCCTGATGTAACAGTTGGTGCAGGTATTCAG
CGCTATTTCAGTCTAAACAAGACTACTGCTGTGCTGGATATATCTATTCCTATTCCAATTTTCGATCGTAATCAGGGAAA
TGAATTGGAAGCCCGCCAGCGCCTGAATAAAGCAATGGATGAACGCGCGTCCGTTGAATTGCAACTTAGAACAGAATTTG
CACGTAACTACGAGAATCTGCTGGCTGCCCGGAATGAGATTCGGGTATTGCATGATGAGGTGTTGCCGGGTGCGCAGAAT
GCCTTTGAGATTACCAATCGGGGTTACCAGCTGGGTAAATTCAGTTTTCTGGAAATGCTGGATACCCAGCGCGCTTTTTT
CCAGAATCGTATTCTTTATGTGCGGGCACTGGCCAATTATCAACGTCTGGTCAATATCATCGAGCAGTTGATTGCAGCAC
CGCTTGCTGATTCAGCTGCAGATTACACAAAGCTCAATACTCAAGGGAAGGAGCGTAATCAATGA

Upstream 100 bases:

>100_bases
TTTACCGGTATGGCGGTTTCGGCATGCCGGATGATTATCTGGATGCCGTCCGACGCTGTTGCAGAAACAGTCTTGTATTT
TGAATATTGAGGTTGTTTTC

Downstream 100 bases:

>100_bases
ACGTTAGCGGACGATTACCCATTGTGGCAGTTATTCTGGTTGGCATTTTGCTAGGGGCGTTGCTTTTGATCCAGGATAAA
TTCAGGCTGCCGGATGCTGA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MISGVYLRHDCSWGIIVIEYQTAKAILRQLRTRQMVLVFASFFAGIIPILGHGMAYADTHPVINISAEKGEDLTLRQALQ
QVLQNNPELAAFSREVAAYEGTKLQAGLLKNPEFSVGAESIDSSNPNIERFTTFRISQLIELGGKRSARVNVATLGQELA
DQAYAAKRLEVVARTANAFIDVLENQVHVSVMDDTLRLMQKAMKTVVKRVEAGKAPPIEATRSKVALSAASIELEQGRRN
LSAARAKLALLWGEAEPRFGQALGELESFVEIPEFDQLVKRLEENPIMLQSLKNIAQREAMVELQKANKIPDVTVGAGIQ
RYFSLNKTTAVLDISIPIPIFDRNQGNELEARQRLNKAMDERASVELQLRTEFARNYENLLAARNEIRVLHDEVLPGAQN
AFEITNRGYQLGKFSFLEMLDTQRAFFQNRILYVRALANYQRLVNIIEQLIAAPLADSAADYTKLNTQGKERNQ

Sequences:

>Translated_474_residues
MISGVYLRHDCSWGIIVIEYQTAKAILRQLRTRQMVLVFASFFAGIIPILGHGMAYADTHPVINISAEKGEDLTLRQALQ
QVLQNNPELAAFSREVAAYEGTKLQAGLLKNPEFSVGAESIDSSNPNIERFTTFRISQLIELGGKRSARVNVATLGQELA
DQAYAAKRLEVVARTANAFIDVLENQVHVSVMDDTLRLMQKAMKTVVKRVEAGKAPPIEATRSKVALSAASIELEQGRRN
LSAARAKLALLWGEAEPRFGQALGELESFVEIPEFDQLVKRLEENPIMLQSLKNIAQREAMVELQKANKIPDVTVGAGIQ
RYFSLNKTTAVLDISIPIPIFDRNQGNELEARQRLNKAMDERASVELQLRTEFARNYENLLAARNEIRVLHDEVLPGAQN
AFEITNRGYQLGKFSFLEMLDTQRAFFQNRILYVRALANYQRLVNIIEQLIAAPLADSAADYTKLNTQGKERNQ
>Mature_474_residues
MISGVYLRHDCSWGIIVIEYQTAKAILRQLRTRQMVLVFASFFAGIIPILGHGMAYADTHPVINISAEKGEDLTLRQALQ
QVLQNNPELAAFSREVAAYEGTKLQAGLLKNPEFSVGAESIDSSNPNIERFTTFRISQLIELGGKRSARVNVATLGQELA
DQAYAAKRLEVVARTANAFIDVLENQVHVSVMDDTLRLMQKAMKTVVKRVEAGKAPPIEATRSKVALSAASIELEQGRRN
LSAARAKLALLWGEAEPRFGQALGELESFVEIPEFDQLVKRLEENPIMLQSLKNIAQREAMVELQKANKIPDVTVGAGIQ
RYFSLNKTTAVLDISIPIPIFDRNQGNELEARQRLNKAMDERASVELQLRTEFARNYENLLAARNEIRVLHDEVLPGAQN
AFEITNRGYQLGKFSFLEMLDTQRAFFQNRILYVRALANYQRLVNIIEQLIAAPLADSAADYTKLNTQGKERNQ

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53037; Mature: 53037

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGVYLRHDCSWGIIVIEYQTAKAILRQLRTRQMVLVFASFFAGIIPILGHGMAYADTH
CCCCEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
PVINISAEKGEDLTLRQALQQVLQNNPELAAFSREVAAYEGTKLQAGLLKNPEFSVGAES
CEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHH
IDSSNPNIERFTTFRISQLIELGGKRSARVNVATLGQELADQAYAAKRLEVVARTANAFI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVLENQVHVSVMDDTLRLMQKAMKTVVKRVEAGKAPPIEATRSKVALSAASIELEQGRRN
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSAARAKLALLWGEAEPRFGQALGELESFVEIPEFDQLVKRLEENPIMLQSLKNIAQREA
HHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
MVELQKANKIPDVTVGAGIQRYFSLNKTTAVLDISIPIPIFDRNQGNELEARQRLNKAMD
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCEEEECCCCCHHHHHHHHHHHHH
ERASVELQLRTEFARNYENLLAARNEIRVLHDEVLPGAQNAFEITNRGYQLGKFSFLEML
HHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHH
DTQRAFFQNRILYVRALANYQRLVNIIEQLIAAPLADSAADYTKLNTQGKERNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MISGVYLRHDCSWGIIVIEYQTAKAILRQLRTRQMVLVFASFFAGIIPILGHGMAYADTH
CCCCEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
PVINISAEKGEDLTLRQALQQVLQNNPELAAFSREVAAYEGTKLQAGLLKNPEFSVGAES
CEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHH
IDSSNPNIERFTTFRISQLIELGGKRSARVNVATLGQELADQAYAAKRLEVVARTANAFI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVLENQVHVSVMDDTLRLMQKAMKTVVKRVEAGKAPPIEATRSKVALSAASIELEQGRRN
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSAARAKLALLWGEAEPRFGQALGELESFVEIPEFDQLVKRLEENPIMLQSLKNIAQREA
HHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
MVELQKANKIPDVTVGAGIQRYFSLNKTTAVLDISIPIPIFDRNQGNELEARQRLNKAMD
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCEEEECCCCCHHHHHHHHHHHHH
ERASVELQLRTEFARNYENLLAARNEIRVLHDEVLPGAQNAFEITNRGYQLGKFSFLEML
HHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHH
DTQRAFFQNRILYVRALANYQRLVNIIEQLIAAPLADSAADYTKLNTQGKERNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]