Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 114330455

GI number: 114330455

Start: 449085

End: 449843

Strand: Reverse

Name: kdsB [H]

Synonym: Neut_0435

Alternate gene names: 114330455

Gene position: 449843-449085 (Counterclockwise)

Preceding gene: 114330462

Following gene: 114330454

Centisome position: 16.9

GC content: 53.62

Gene sequence:

>759_bases
ATGAAAACAATCGCCATCATTCCGGCACGCATGGATTCTTCGCGTTTTCCCGGAAAACCGTTAGCGCAGCTGCTGGACTG
CACCATGCTGGAGCATGTTTACCAGCGTGTTGCCATGAGCAAATCGCTGAGCGCAACTTATATCGCCACCTGTGACGAAG
CCATCCGGCAGGCAGCAACCGCTTTCGGAGCACCCGTCATCATGACTGCAGACAGCCACGAACGGGCCAGTGACCGCATC
GCGGAAGCAACCGCACACACCGATGCTGATCTGATCGTCATGGTGCAGGGAGATGAACCGATGACACATCCTTCCATGAT
CGACACCGCCATCGCACCTTTCCACAATGATCCCAAACTGGAATGCGTCAATCTGACGAAGCGAATCGACGATGAAGCCG
ATTTTCGCAGCCCCAACACCATCAAAGTGGTTACGGATCAGCAGGGAAATGCGTTATATATGACCCGTCAGCCGATTCCG
ACATTGGCTCCAGGTGGCTTTGGAGCAACTGCCACTTACAAGCAGGTCTGTATCATTCCTTTTACACGCACCTGTCTGCT
CGAATACAGCCAGTTATCGCCCACCCCACTGGAATGCCTCGAATCAATTGATATGCTGCGCCTGCTGGAACACGGCCGCC
GCGTCAGGATGGTGGAAACTGAATACGATACGCAGGCAGTTGATACCGAGGCAGATCTGGCCCGTGTTGCGCAGCTGATG
GCTAATGATCCGCTACTGGGCAAATATCAAAGAATCTAA

Upstream 100 bases:

>100_bases
TACCTATGAATCCAGCAAACCAGCCGCAGCACGCACTGCAAAAAATATTTTATTCGCCCCATCATATCTGCATATTTAAC
CAGTCACTTTTCCCATAACT

Downstream 100 bases:

>100_bases
CTGGAGCGCTTATGTCACTGAAAGCCCGTCTCACCCATCATGAACTGACCATTGGCTCATGGATCACGCTCGGACACCCC
TCAATTGCTGAGATCATGGC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKTIAIIPARMDSSRFPGKPLAQLLDCTMLEHVYQRVAMSKSLSATYIATCDEAIRQAATAFGAPVIMTADSHERASDRI
AEATAHTDADLIVMVQGDEPMTHPSMIDTAIAPFHNDPKLECVNLTKRIDDEADFRSPNTIKVVTDQQGNALYMTRQPIP
TLAPGGFGATATYKQVCIIPFTRTCLLEYSQLSPTPLECLESIDMLRLLEHGRRVRMVETEYDTQAVDTEADLARVAQLM
ANDPLLGKYQRI

Sequences:

>Translated_252_residues
MKTIAIIPARMDSSRFPGKPLAQLLDCTMLEHVYQRVAMSKSLSATYIATCDEAIRQAATAFGAPVIMTADSHERASDRI
AEATAHTDADLIVMVQGDEPMTHPSMIDTAIAPFHNDPKLECVNLTKRIDDEADFRSPNTIKVVTDQQGNALYMTRQPIP
TLAPGGFGATATYKQVCIIPFTRTCLLEYSQLSPTPLECLESIDMLRLLEHGRRVRMVETEYDTQAVDTEADLARVAQLM
ANDPLLGKYQRI
>Mature_252_residues
MKTIAIIPARMDSSRFPGKPLAQLLDCTMLEHVYQRVAMSKSLSATYIATCDEAIRQAATAFGAPVIMTADSHERASDRI
AEATAHTDADLIVMVQGDEPMTHPSMIDTAIAPFHNDPKLECVNLTKRIDDEADFRSPNTIKVVTDQQGNALYMTRQPIP
TLAPGGFGATATYKQVCIIPFTRTCLLEYSQLSPTPLECLESIDMLRLLEHGRRVRMVETEYDTQAVDTEADLARVAQLM
ANDPLLGKYQRI

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=245, Percent_Identity=33.469387755102, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27887; Mature: 27887

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIAIIPARMDSSRFPGKPLAQLLDCTMLEHVYQRVAMSKSLSATYIATCDEAIRQAAT
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AFGAPVIMTADSHERASDRIAEATAHTDADLIVMVQGDEPMTHPSMIDTAIAPFHNDPKL
HHCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCE
ECVNLTKRIDDEADFRSPNTIKVVTDQQGNALYMTRQPIPTLAPGGFGATATYKQVCIIP
EEEHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHEEEEEC
FTRTCLLEYSQLSPTPLECLESIDMLRLLEHGRRVRMVETEYDTQAVDTEADLARVAQLM
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCCHHHHHHHHHHH
ANDPLLGKYQRI
HCCCCCCHHCCC
>Mature Secondary Structure
MKTIAIIPARMDSSRFPGKPLAQLLDCTMLEHVYQRVAMSKSLSATYIATCDEAIRQAAT
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AFGAPVIMTADSHERASDRIAEATAHTDADLIVMVQGDEPMTHPSMIDTAIAPFHNDPKL
HHCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCE
ECVNLTKRIDDEADFRSPNTIKVVTDQQGNALYMTRQPIPTLAPGGFGATATYKQVCIIP
EEEHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHEEEEEC
FTRTCLLEYSQLSPTPLECLESIDMLRLLEHGRRVRMVETEYDTQAVDTEADLARVAQLM
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCCHHHHHHHHHHH
ANDPLLGKYQRI
HCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA