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The map label for this gene is suhB [H]

Identifier: 114330428

GI number: 114330428

Start: 414182

End: 415009

Strand: Reverse

Name: suhB [H]

Synonym: Neut_0407

Alternate gene names: 114330428

Gene position: 415009-414182 (Counterclockwise)

Preceding gene: 114330430

Following gene: 114330427

Centisome position: 15.6

GC content: 51.33

Gene sequence:

>828_bases
ATGCATCCCACGCTTACCATCGCAGTTAAGGCAGCTCGCCGGGCCGGCAACATCATCAATCGTGCCTCAATGGATTTGGA
TCGGCTGACTGTTTCGCGCAAAGCTCACAGCGATTTTGTCAGCGAAGTGGACAAAGCTGCTGAAGATGCCATTATCAAAA
TATTGCTGGATGCATACCCTGATCATTCGATTCTAGCAGAAGAAAGCGGTGCCAGCGGGAATGCAAACAAATCGGAATAT
CAGTGGATAATTGATCCATTGGACGGCACCACCAATTTCCTGCACGGATTTCCAAAATACTGCGTCTCGATCGCGTTGTT
ACACCGTGGAATTTTGTCACAAGCTGTCATCTACGATCCGGTAAGCGATGAATTATTTACTGCCACGCGCGGCAGCGGTG
CCTTTCTCAATGATCATCGTATTCGTGTTGGCAAACGAGCGCAGTTAGGCGAATGCCTGATCGGCACTGGATTCCCGTTT
AGAGATTTCACACATATGGATGCCTATCTGGCCATGTTCAGAGACATGATTCCCAAAACAGCCGGCATTCGCCGCCCGGG
CTCTGCGGCACTGGATCTCGCTTACGTTGCCGCCGGACGTTACGATGGCTTCTGGGAAACCGGGTTGGCGCCGTGGGACA
TTGCAGCCGGATGTCTGCTTATTCTCGAAGCAGGAGGTATGGTTGGTGATTTGGAAGGGAACGGACATTACATGCAAAGT
GGGCAGATCGTTGCAGGCAATCCCAAAATCTTCTCCCAGCTTCTGCAAATTATCACCCCCCATCTGACCGAACAGCTTCT
TGCCGAGAACCGCGAGTTGCCCAAGTAA

Upstream 100 bases:

>100_bases
GTATGGCTCAACACAATCCGGACATTATCGAGCGGCGAGGCAGGATTCATATTAGAATAGCGGTTTTCCAGTCATTTGTT
TCTAAAGTAAATTTTTTACC

Downstream 100 bases:

>100_bases
TTTGAGTTAATCACAGGAGAACCTGATGGAGAACCGAGCACACGCATTTGCTGCCGGTCTGTTCGTACTCCTCCTGGGAG
TAGCGGCGGTCATGGCGGTC

Product: inositol-phosphate phosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MHPTLTIAVKAARRAGNIINRASMDLDRLTVSRKAHSDFVSEVDKAAEDAIIKILLDAYPDHSILAEESGASGNANKSEY
QWIIDPLDGTTNFLHGFPKYCVSIALLHRGILSQAVIYDPVSDELFTATRGSGAFLNDHRIRVGKRAQLGECLIGTGFPF
RDFTHMDAYLAMFRDMIPKTAGIRRPGSAALDLAYVAAGRYDGFWETGLAPWDIAAGCLLILEAGGMVGDLEGNGHYMQS
GQIVAGNPKIFSQLLQIITPHLTEQLLAENRELPK

Sequences:

>Translated_275_residues
MHPTLTIAVKAARRAGNIINRASMDLDRLTVSRKAHSDFVSEVDKAAEDAIIKILLDAYPDHSILAEESGASGNANKSEY
QWIIDPLDGTTNFLHGFPKYCVSIALLHRGILSQAVIYDPVSDELFTATRGSGAFLNDHRIRVGKRAQLGECLIGTGFPF
RDFTHMDAYLAMFRDMIPKTAGIRRPGSAALDLAYVAAGRYDGFWETGLAPWDIAAGCLLILEAGGMVGDLEGNGHYMQS
GQIVAGNPKIFSQLLQIITPHLTEQLLAENRELPK
>Mature_275_residues
MHPTLTIAVKAARRAGNIINRASMDLDRLTVSRKAHSDFVSEVDKAAEDAIIKILLDAYPDHSILAEESGASGNANKSEY
QWIIDPLDGTTNFLHGFPKYCVSIALLHRGILSQAVIYDPVSDELFTATRGSGAFLNDHRIRVGKRAQLGECLIGTGFPF
RDFTHMDAYLAMFRDMIPKTAGIRRPGSAALDLAYVAAGRYDGFWETGLAPWDIAAGCLLILEAGGMVGDLEGNGHYMQS
GQIVAGNPKIFSQLLQIITPHLTEQLLAENRELPK

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=259, Percent_Identity=38.2239382239382, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI5031789, Length=251, Percent_Identity=31.8725099601594, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI221625487, Length=251, Percent_Identity=31.8725099601594, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI221625507, Length=141, Percent_Identity=34.7517730496454, Blast_Score=95, Evalue=7e-20,
Organism=Escherichia coli, GI1788882, Length=266, Percent_Identity=48.8721804511278, Blast_Score=258, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI193202572, Length=247, Percent_Identity=30.7692307692308, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI193202570, Length=263, Percent_Identity=30.0380228136882, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320493, Length=203, Percent_Identity=36.4532019704434, Blast_Score=129, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6321836, Length=233, Percent_Identity=31.7596566523605, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21357329, Length=264, Percent_Identity=34.0909090909091, Blast_Score=154, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24664922, Length=258, Percent_Identity=31.7829457364341, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21357303, Length=232, Percent_Identity=32.7586206896552, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24664926, Length=231, Percent_Identity=29.8701298701299, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357957, Length=223, Percent_Identity=31.8385650224215, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24664918, Length=263, Percent_Identity=30.4182509505703, Blast_Score=98, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 30010; Mature: 30010

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPTLTIAVKAARRAGNIINRASMDLDRLTVSRKAHSDFVSEVDKAAEDAIIKILLDAYP
CCCCEEEEEHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHSILAEESGASGNANKSEYQWIIDPLDGTTNFLHGFPKYCVSIALLHRGILSQAVIYDP
CCCEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
VSDELFTATRGSGAFLNDHRIRVGKRAQLGECLIGTGFPFRDFTHMDAYLAMFRDMIPKT
CCCHHEEECCCCCCEECCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHH
AGIRRPGSAALDLAYVAAGRYDGFWETGLAPWDIAAGCLLILEAGGMVGDLEGNGHYMQS
CCCCCCCCHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHEEECCCCEEECCCCCEEEEC
GQIVAGNPKIFSQLLQIITPHLTEQLLAENRELPK
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHPTLTIAVKAARRAGNIINRASMDLDRLTVSRKAHSDFVSEVDKAAEDAIIKILLDAYP
CCCCEEEEEHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHSILAEESGASGNANKSEYQWIIDPLDGTTNFLHGFPKYCVSIALLHRGILSQAVIYDP
CCCEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
VSDELFTATRGSGAFLNDHRIRVGKRAQLGECLIGTGFPFRDFTHMDAYLAMFRDMIPKT
CCCHHEEECCCCCCEECCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHH
AGIRRPGSAALDLAYVAAGRYDGFWETGLAPWDIAAGCLLILEAGGMVGDLEGNGHYMQS
CCCCCCCCHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHEEECCCCEEECCCCCEEEEC
GQIVAGNPKIFSQLLQIITPHLTEQLLAENRELPK
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]