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The map label for this gene is insF1 [H]

Identifier: 114330384

GI number: 114330384

Start: 364924

End: 365541

Strand: Direct

Name: insF1 [H]

Synonym: Neut_0361

Alternate gene names: 114330384

Gene position: 364924-365541 (Clockwise)

Preceding gene: 114330383

Following gene: 114330385

Centisome position: 13.71

GC content: 44.01

Gene sequence:

>618_bases
ATGCGAGAAGCAGATGTGCAAGTGAGGCACCGGAAAAAGTACAAGGTCACAACTAACAGTAATCACAAACAACCGATATT
TGAGAATAGGCTGAATCGGCAATTTGATGTTGCAGCCCCCAATCAAATCTACGTTGGTGACATTACCTGCATTTGGACCC
GGGAAGGCTGGTTGTATCTGGCGGTGGTCATTGATTTGTTTTCCAGGAAGGTGGTGGGTTGGAGCATGAGTTCAAGAATG
AAAGCAAAGCTGGTTTGTGATGCATTGAGAATGGCTGTCTGGCAGCGTCAACCACAACCTGGATTGATTGTACATTCAGA
TCGTGGATCGCAATATGCCAGTAAGCAGTACCGCCAACTTTTAAAAATACACGGCTTTATCGGCAGTATGAGTCGTAGGG
GAAATTGTTGGGATAATTCAGTGGCTGAAAGCTTTTTCGGTAGCCTTAAACGGGAGCAAATCCACTGGCAACATTATCCA
ACCCGCCATAAAGCACAACAAGATGTACTGCAGTATATTTCCATGTTCTATAACAGCCAGCGACTGCATTCATACCCGGG
TTACAAAAACCCGAATCAATATGAGATGGAAATGGAAATAGTGAAAAATGTTGCTTAA

Upstream 100 bases:

>100_bases
GATAGCAAAATCCAGTCATCATAGCTACGGCAGTCGCAGAATCGGAAAAGCGCTGAATGCACGGGGTTATCCGGTTGGTC
GCAGGAAGGCTCGAAGCCTG

Downstream 100 bases:

>100_bases
CTGGAGTGTCCGGTTTTACTTGACCAGGTCAATACACCGCGCAACGTGACCGGGGGACTGGATCGCAGCCGATGGATGGC
CGGTGCACCCAATCCGTCGG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MREADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRM
KAKLVCDALRMAVWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYP
TRHKAQQDVLQYISMFYNSQRLHSYPGYKNPNQYEMEMEIVKNVA

Sequences:

>Translated_205_residues
MREADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRM
KAKLVCDALRMAVWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYP
TRHKAQQDVLQYISMFYNSQRLHSYPGYKNPNQYEMEMEIVKNVA
>Mature_205_residues
MREADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRM
KAKLVCDALRMAVWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYP
TRHKAQQDVLQYISMFYNSQRLHSYPGYKNPNQYEMEMEIVKNVA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=156, Percent_Identity=39.7435897435897, Blast_Score=114, Evalue=7e-26,
Organism=Escherichia coli, GI1788405, Length=195, Percent_Identity=47.6923076923077, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1787263, Length=195, Percent_Identity=47.6923076923077, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1786753, Length=195, Percent_Identity=47.6923076923077, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1786570, Length=195, Percent_Identity=47.6923076923077, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1786490, Length=195, Percent_Identity=47.6923076923077, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1789981, Length=154, Percent_Identity=38.961038961039, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 24245; Mature: 24245

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYL
CCCCCCHHHHCCEEEEECCCCCCCCHHHHHCCCEEECCCCCEEEEEEEEEEEECCCHHHH
AVVIDLFSRKVVGWSMSSRMKAKLVCDALRMAVWQRQPQPGLIVHSDRGSQYASKQYRQL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHH
LKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVLQYISMFYNSQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
RLHSYPGYKNPNQYEMEMEIVKNVA
HHHCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MREADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYL
CCCCCCHHHHCCEEEEECCCCCCCCHHHHHCCCEEECCCCCEEEEEEEEEEEECCCHHHH
AVVIDLFSRKVVGWSMSSRMKAKLVCDALRMAVWQRQPQPGLIVHSDRGSQYASKQYRQL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHH
LKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVLQYISMFYNSQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
RLHSYPGYKNPNQYEMEMEIVKNVA
HHHCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]