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The map label for this gene is atpA1

Identifier: 114330302

GI number: 114330302

Start: 284822

End: 286363

Strand: Direct

Name: atpA1

Synonym: Neut_0275

Alternate gene names: 114330302

Gene position: 284822-286363 (Clockwise)

Preceding gene: 114330301

Following gene: 114330303

Centisome position: 10.7

GC content: 44.1

Gene sequence:

>1542_bases
ATGCAGTTAAATCCATCAGAAATCAGTGAATTAATCAAGAGTAAAATTGAAGGCCTTTCCGTTACATCGGAATTTCGTAC
GCAAGGAACTATTGTATCGTTGACGGATGGTATCGTTCGAGTGCACGGTCTTTCTGACGTAATGCAAGGCGAGATGCTGG
AGTTTCCGGGTGGGACGTATGGCCTGGCGTTAAATTTGGAGCGTGATTCGGTTGGTGCGGTTATCTTAGGTGCTTACGAA
CATCTTACGGAAGGAGATATCGTAAAATGTACTGGCAGAGTTCTTGAGGTTCCTGTAGGAGAGGCTTTGCTGGGTCGTGT
CGTAAATGCTTTAGGGCAGCCGATTGATGGTAAAGGACCTGTAGCTGCACAGGGAATGGAGCCAATAGAGAAAATTGCTC
CTGGCGTCATATCACGTAAATCAGTTGATCAACCAATGCAAACTGGCTTGAAATCGGTTGATTCAATGGTTCCGATCGGA
AGAGGGCAGCGTGAGTTGATCATTGGAGATCGGCAGACAGGTAAAACAGCAGTTGCAATTGATGCGATCATTAATCAAAA
GGGTGAAGATATGATCTGCATCTATGTTGCAATAGGCCAGAAAGCTTCATCAATTGCAAATGTGGTGCGTAAACTGGAAG
AAGTTGGTGCCATGGCATATACCATTGTGGTAGTGGCTTCTGCTTCTGAATCAGCAGCTATGCAGTATATTGCACCTTAT
TCTGGCTGTACCATGGGTGAATATTTTCGTGACAAGGGGCAAGATGCGCTGATTGTCTATGATGACCTAACTAAGCAGGC
ATGGGCTTATCGTCAGATTTCTTTGTTGTTGCGCCGACCTCCTGGTCGTGAGGCTTATCCGGGAGATGTTTTCTATCTTC
ACTCTCGTTTATTAGAAAGAGCAGCAAGAGTGAATGCTGATTATGTTGAAAAAGCTACTGGTGGAAAAGTAAAAGGAAAA
ACAGGATCGCTAACCGCGTTACCTATTATTGAAACTCAAGCAGGTGACGTAACGGCATTTGTACCTACTAACGTAATTTC
AATTACGGATGGTCAGATATTCCTTGAGTCTGATTTATTTAATGCAGGTATACGGCCGGCAATCAATGCTGGTGTTTCGG
TTTCCAGAGTTGGAGGCGCTGCTCAGACCAAGGTCATCAAAAAACTAGGCGGTGGTATTCGTTTGGCTTTGGCGCAATAT
CGTGAACTTGCTGCTTTTGCACAGTTTGCTTCTGATCTTGATGAGGCCACACGTAAGCAACTGGAGCGTGGAAAAATGGC
TACAGAGTTAATGAAGCAGGCGCAGTACGCTACATTAAAAGTTTCAGAGATGGCATTAACACTGTTTGCGTTGAATAAAG
GTTATTTTGATGATGTTGACATTAAGCGCGCTCTTGCTTTTGAGTCTGCATTAAAAAGCCATGTTCGTAGTCATCATGCT
GCAATACTGGATAAGATCGAGACAACCAAGGAGCTTGACGCTGAAACAGAAAAGGCGTTAGAAGCAGCTATTCAGGAATT
TAAGCAGAACGGGATATACTAA

Upstream 100 bases:

>100_bases
TGGCGTAAAAATTGAAATCGGTGACCAGGTGATTGACAGTTCTGTGTCCGGAAAGCTGGAAGCTATGGCGGCGACTCTCA
AAAGCTAGGAGTGATATAAA

Downstream 100 bases:

>100_bases
CCCATGGCAAGCAGCAGAGAAATACGAAACAAAATCAAGAGTATTAAAAATACGCAAAAGATTACGCGTGCGATGGAAAT
GGTTGCTGCCTCCAAGATGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNPSEISELIKSKIEGLSVTSEFRTQGTIVSLTDGIVRVHGLSDVMQGEMLEFPGGTYGLALNLERDSVGAVILGAYE
HLTEGDIVKCTGRVLEVPVGEALLGRVVNALGQPIDGKGPVAAQGMEPIEKIAPGVISRKSVDQPMQTGLKSVDSMVPIG
RGQRELIIGDRQTGKTAVAIDAIINQKGEDMICIYVAIGQKASSIANVVRKLEEVGAMAYTIVVVASASESAAMQYIAPY
SGCTMGEYFRDKGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEKATGGKVKGK
TGSLTALPIIETQAGDVTAFVPTNVISITDGQIFLESDLFNAGIRPAINAGVSVSRVGGAAQTKVIKKLGGGIRLALAQY
RELAAFAQFASDLDEATRKQLERGKMATELMKQAQYATLKVSEMALTLFALNKGYFDDVDIKRALAFESALKSHVRSHHA
AILDKIETTKELDAETEKALEAAIQEFKQNGIY

Sequences:

>Translated_513_residues
MQLNPSEISELIKSKIEGLSVTSEFRTQGTIVSLTDGIVRVHGLSDVMQGEMLEFPGGTYGLALNLERDSVGAVILGAYE
HLTEGDIVKCTGRVLEVPVGEALLGRVVNALGQPIDGKGPVAAQGMEPIEKIAPGVISRKSVDQPMQTGLKSVDSMVPIG
RGQRELIIGDRQTGKTAVAIDAIINQKGEDMICIYVAIGQKASSIANVVRKLEEVGAMAYTIVVVASASESAAMQYIAPY
SGCTMGEYFRDKGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEKATGGKVKGK
TGSLTALPIIETQAGDVTAFVPTNVISITDGQIFLESDLFNAGIRPAINAGVSVSRVGGAAQTKVIKKLGGGIRLALAQY
RELAAFAQFASDLDEATRKQLERGKMATELMKQAQYATLKVSEMALTLFALNKGYFDDVDIKRALAFESALKSHVRSHHA
AILDKIETTKELDAETEKALEAAIQEFKQNGIY
>Mature_513_residues
MQLNPSEISELIKSKIEGLSVTSEFRTQGTIVSLTDGIVRVHGLSDVMQGEMLEFPGGTYGLALNLERDSVGAVILGAYE
HLTEGDIVKCTGRVLEVPVGEALLGRVVNALGQPIDGKGPVAAQGMEPIEKIAPGVISRKSVDQPMQTGLKSVDSMVPIG
RGQRELIIGDRQTGKTAVAIDAIINQKGEDMICIYVAIGQKASSIANVVRKLEEVGAMAYTIVVVASASESAAMQYIAPY
SGCTMGEYFRDKGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEKATGGKVKGK
TGSLTALPIIETQAGDVTAFVPTNVISITDGQIFLESDLFNAGIRPAINAGVSVSRVGGAAQTKVIKKLGGGIRLALAQY
RELAAFAQFASDLDEATRKQLERGKMATELMKQAQYATLKVSEMALTLFALNKGYFDDVDIKRALAFESALKSHVRSHHA
AILDKIETTKELDAETEKALEAAIQEFKQNGIY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=57.0588235294118, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=57.0588235294118, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI19913428, Length=314, Percent_Identity=28.0254777070064, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI19913426, Length=314, Percent_Identity=27.7070063694268, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI32189394, Length=364, Percent_Identity=26.0989010989011, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI19913424, Length=263, Percent_Identity=26.9961977186312, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790172, Length=508, Percent_Identity=70.4724409448819, Blast_Score=745, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=355, Percent_Identity=25.9154929577465, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788251, Length=283, Percent_Identity=28.2685512367491, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=510, Percent_Identity=56.2745098039216, Blast_Score=577, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988080, Length=510, Percent_Identity=56.2745098039216, Blast_Score=576, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988074, Length=510, Percent_Identity=52.3529411764706, Blast_Score=522, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17510931, Length=381, Percent_Identity=26.509186351706, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=307, Percent_Identity=28.3387622149837, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=364, Percent_Identity=25.8241758241758, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17565854, Length=262, Percent_Identity=27.4809160305344, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=53.8160469667319, Blast_Score=561, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6319603, Length=378, Percent_Identity=27.7777777777778, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=367, Percent_Identity=26.9754768392371, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=54.9019607843137, Blast_Score=568, Evalue=1e-162,
Organism=Drosophila melanogaster, GI281361666, Length=309, Percent_Identity=26.8608414239482, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646341, Length=309, Percent_Identity=26.8608414239482, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136796, Length=309, Percent_Identity=26.8608414239482, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24638766, Length=324, Percent_Identity=25.6172839506173, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=25.2336448598131, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583988, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583986, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583984, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583992, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129479, Length=333, Percent_Identity=25.5255255255255, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA1_NITEC (Q0AJB2)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746524.1
- ProteinModelPortal:   Q0AJB2
- SMR:   Q0AJB2
- STRING:   Q0AJB2
- GeneID:   4272118
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0275
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q0AJB2
- ProtClustDB:   PRK09281
- BioCyc:   NEUT335283:NEUT_0275-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55241; Mature: 55241

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPSEISELIKSKIEGLSVTSEFRTQGTIVSLTDGIVRVHGLSDVMQGEMLEFPGGTY
CCCCHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCEEEECCHHHHHCCCCEECCCCCE
GLALNLERDSVGAVILGAYEHLTEGDIVKCTGRVLEVPVGEALLGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEEEHHHHCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
VAAQGMEPIEKIAPGVISRKSVDQPMQTGLKSVDSMVPIGRGQRELIIGDRQTGKTAVAI
CCCCCCCHHHHHCCCHHCHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEEH
DAIINQKGEDMICIYVAIGQKASSIANVVRKLEEVGAMAYTIVVVASASESAAMQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHCCCC
SGCTMGEYFRDKGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNADYVEKATGGKVKGKTGSLTALPIIETQAGDVTAFVPTNVISITDGQIFLESDLF
HHHCCHHHHHHCCCCEECCCCCCEEEEEEEEECCCCEEEEECCCEEEEECCEEEEECCHH
NAGIRPAINAGVSVSRVGGAAQTKVIKKLGGGIRLALAQYRELAAFAQFASDLDEATRKQ
CCCCCCHHHCCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGKMATELMKQAQYATLKVSEMALTLFALNKGYFDDVDIKRALAFESALKSHVRSHHA
HHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AILDKIETTKELDAETEKALEAAIQEFKQNGIY
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNPSEISELIKSKIEGLSVTSEFRTQGTIVSLTDGIVRVHGLSDVMQGEMLEFPGGTY
CCCCHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCEEEECCHHHHHCCCCEECCCCCE
GLALNLERDSVGAVILGAYEHLTEGDIVKCTGRVLEVPVGEALLGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEEEHHHHCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
VAAQGMEPIEKIAPGVISRKSVDQPMQTGLKSVDSMVPIGRGQRELIIGDRQTGKTAVAI
CCCCCCCHHHHHCCCHHCHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEEH
DAIINQKGEDMICIYVAIGQKASSIANVVRKLEEVGAMAYTIVVVASASESAAMQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHCCCC
SGCTMGEYFRDKGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNADYVEKATGGKVKGKTGSLTALPIIETQAGDVTAFVPTNVISITDGQIFLESDLF
HHHCCHHHHHHCCCCEECCCCCCEEEEEEEEECCCCEEEEECCCEEEEECCEEEEECCHH
NAGIRPAINAGVSVSRVGGAAQTKVIKKLGGGIRLALAQYRELAAFAQFASDLDEATRKQ
CCCCCCHHHCCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGKMATELMKQAQYATLKVSEMALTLFALNKGYFDDVDIKRALAFESALKSHVRSHHA
HHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AILDKIETTKELDAETEKALEAAIQEFKQNGIY
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA