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The map label for this gene is atpB [H]

Identifier: 114330298

GI number: 114330298

Start: 282634

End: 283443

Strand: Direct

Name: atpB [H]

Synonym: Neut_0271

Alternate gene names: 114330298

Gene position: 282634-283443 (Clockwise)

Preceding gene: 114330297

Following gene: 114330299

Centisome position: 10.62

GC content: 42.22

Gene sequence:

>810_bases
ATGTCAACTGAAGCTGAGTTAAACCCAACATCGTACATACAGCATCACTTAACACATATGACGATGAGCATCGGAGAGGG
TTCATTCTGGGTTTTGCATGTGGATACACTGGTGATGTCATTGATACTTGGCGTGATCAGTCTTGGTTTTATTTGGATGG
TTGTTAGGAAAGCTACGTCGGGAGTCCCCGGTAAAACACAGGCTTTTGTTGAGTTGTTGATAGAATTTATAGATGATCAG
GTAAAAAATACATTTCACGGAAATCGTCATGCCTTTGTTGCCCCGGCGGCGTTAACAATTTTTGTCTGGGTTCTTCTGTT
AAATTCCATGGATTTTTTGCCTGTCGATATTATGGCGTGGATTTACGAGCACTTGTTCGGTCTGCATAACTGGCGAGGTG
TGCCGACGGCAGATGTTAATACAACTTTTGCACTTGCGCTTTCTATCTGGATGCTAACAATTTACTTCAGCATCAAAGTA
AAGGGTTTTGGAGGGTGGATTAAAGAGTTGTTTTGCGCCCCTTTCGGCAAGAATCCTATATTGTGGCCGTTTAATTTGTT
GTTGAATCTGATTGAATACATCTCAAAGCCTTTATCTCATTCTTTGCGACTTTTTGGGAACATGTATGCGGGTGAGATTA
TTTTTATGTTGCTCGGTATGTGGGCGGCAACAGGGATCGCCGGTACAATTTTTGGAGCTGTCCTTGGTGTTGGTTGGGCA
ATTTTTCACATACTGATCGTGGTGTTGCATGCGTTTATATTTATGATACTGGCTGTGGTTTATCTTTCCATGGCGCATGA
ATCACATTGA

Upstream 100 bases:

>100_bases
TCGTTTACTGTTGCTGTATTGATGTCAAGCATGGCAGTGTTTGTTTCAGAAAAGCCTCCTGTTAAATGAACATATCAAAT
AACGTAATAAAGGTAAGTAG

Downstream 100 bases:

>100_bases
TTTAAAAGGTTTTTTGTTATTAACTTGAACTAAAGGGAAAAATATGGATAACGTTCAATTTCTTGCAATGATTCAGGCGT
ATACCGGAATTGGTATTGGA

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSTEAELNPTSYIQHHLTHMTMSIGEGSFWVLHVDTLVMSLILGVISLGFIWMVVRKATSGVPGKTQAFVELLIEFIDDQ
VKNTFHGNRHAFVAPAALTIFVWVLLLNSMDFLPVDIMAWIYEHLFGLHNWRGVPTADVNTTFALALSIWMLTIYFSIKV
KGFGGWIKELFCAPFGKNPILWPFNLLLNLIEYISKPLSHSLRLFGNMYAGEIIFMLLGMWAATGIAGTIFGAVLGVGWA
IFHILIVVLHAFIFMILAVVYLSMAHESH

Sequences:

>Translated_269_residues
MSTEAELNPTSYIQHHLTHMTMSIGEGSFWVLHVDTLVMSLILGVISLGFIWMVVRKATSGVPGKTQAFVELLIEFIDDQ
VKNTFHGNRHAFVAPAALTIFVWVLLLNSMDFLPVDIMAWIYEHLFGLHNWRGVPTADVNTTFALALSIWMLTIYFSIKV
KGFGGWIKELFCAPFGKNPILWPFNLLLNLIEYISKPLSHSLRLFGNMYAGEIIFMLLGMWAATGIAGTIFGAVLGVGWA
IFHILIVVLHAFIFMILAVVYLSMAHESH
>Mature_268_residues
STEAELNPTSYIQHHLTHMTMSIGEGSFWVLHVDTLVMSLILGVISLGFIWMVVRKATSGVPGKTQAFVELLIEFIDDQV
KNTFHGNRHAFVAPAALTIFVWVLLLNSMDFLPVDIMAWIYEHLFGLHNWRGVPTADVNTTFALALSIWMLTIYFSIKVK
GFGGWIKELFCAPFGKNPILWPFNLLLNLIEYISKPLSHSLRLFGNMYAGEIIFMLLGMWAATGIAGTIFGAVLGVGWAI
FHILIVVLHAFIFMILAVVYLSMAHESH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=279, Percent_Identity=45.5197132616487, Blast_Score=226, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 30170; Mature: 30039

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEAELNPTSYIQHHLTHMTMSIGEGSFWVLHVDTLVMSLILGVISLGFIWMVVRKATS
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVPGKTQAFVELLIEFIDDQVKNTFHGNRHAFVAPAALTIFVWVLLLNSMDFLPVDIMAW
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IYEHLFGLHNWRGVPTADVNTTFALALSIWMLTIYFSIKVKGFGGWIKELFCAPFGKNPI
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCC
LWPFNLLLNLIEYISKPLSHSLRLFGNMYAGEIIFMLLGMWAATGIAGTIFGAVLGVGWA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFHILIVVLHAFIFMILAVVYLSMAHESH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STEAELNPTSYIQHHLTHMTMSIGEGSFWVLHVDTLVMSLILGVISLGFIWMVVRKATS
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVPGKTQAFVELLIEFIDDQVKNTFHGNRHAFVAPAALTIFVWVLLLNSMDFLPVDIMAW
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IYEHLFGLHNWRGVPTADVNTTFALALSIWMLTIYFSIKVKGFGGWIKELFCAPFGKNPI
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCC
LWPFNLLLNLIEYISKPLSHSLRLFGNMYAGEIIFMLLGMWAATGIAGTIFGAVLGVGWA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFHILIVVLHAFIFMILAVVYLSMAHESH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]