Click here to switch to the map view.

The map label for this gene is ftsW [H]

Identifier: 114330274

GI number: 114330274

Start: 260161

End: 261321

Strand: Reverse

Name: ftsW [H]

Synonym: Neut_0247

Alternate gene names: 114330274

Gene position: 261321-260161 (Counterclockwise)

Preceding gene: 114330275

Following gene: 114330273

Centisome position: 9.82

GC content: 47.72

Gene sequence:

>1161_bases
ATGATAAGTCCATCCACTACACATAATCAGCCAATCCAGCCCGAACTAGATCTGCATCTGCTTTCAGCTGTTCTGCTGTT
GCTGGGCCTAGGACTGGTCATGGTGTATTCCGCCTCGATTGCGATCGCCGAATCAAAATATGGTGAGGGCGGTACTTATT
ATTTTCTTGTCCGGCAAGCTCTTTCTATCCTATTGGGAATATTTGCCGGGATGGTCGCTTTCCAGGTCTCGTTACGCCAG
TGGCAAACTTATTCTCACTATCTGCTTGCAATAGGTATTGTACTGCTGACCGTAGTGCTGATCCCGGGTATCGGCCTTGA
AATCAATGGCAGCCGTCGCTGGCTGCCTCTGGTGATATTTAATTTCCAGCCTTCCGAGCTGATGAAGTTACTCATTTTGA
TTTTTACAGCAGATTACGTTGTACGCAAAACCGCTTACAAGGATCACTTTTTCAAAGGTTTTCTGCCCATCCTTACATTA
CTGGCTATTGTTTCCCTACTTTTGCTGATGGAACCGGATCTGGGGGCTGCAGTGATCATAGCTGCCATCGTGCTATCCAT
CATGTTTATCAACGGAATGAGCCTGAAAATGTTTCTGGGGCTGTTATGCCTGATACCAATCCCGCTAATTCTGCTGATTA
TATTTGAGCCTTATCGTATGGATCGGATCAACGCTATTTTTGATCCCTGGAATGATCCATTCAATAAAGGCTACCAGCTC
ACCCATGCACTAATCGCGTTCGGGCTTGGTGAATGGTGGGGAGTGGGGCTTGGAGGCAGTGTAGAAAAATTAAATTATCT
GCCCGAGGCCCACACTGATTTCATGTTTGCCGTACTGGCCGAAGAACTTGGTTTTGCAGGCGTGGCCACTGTTATAGCGC
TGTTTTTCTTTCTGTTAATCCGCACATTCAGAATCGGCCGTGCGGCAGCCACCCAGGGAGATCAATTCGGGGCACTGGTC
GCGCAAGGTATCGGGGTCTGGCTGGGTTTTCAGGCTTTCATCAACATGGGCGTAAACATGGGCCTGCTTCCTACCAAAGG
CTTGACATTGCCATTCATGAGCTATGGCGGCAGCAGTATCGTTATCAACAGTATTGCAATTGCCATATTGCTGCGGATTG
ATTGGGAAAATCGGCAAAAACGCAGAGGGCTAAATGTATGA

Upstream 100 bases:

>100_bases
ATGTTCAACAACTACATCCATCGCGCTGAGGTTTTTACGACCGCTGTCCAGGGAATCGAACACAAATTTATACTCACGGC
ACAGACATGTCACTAACCGT

Downstream 100 bases:

>100_bases
ATAAACACCTGCAATCCGGTCCATGGCATACACCACATGTGGAGTTCACAGCTTGTCCCGCACAATCATGATCATGGCAG
GGGGAACCGGTGGACATGTA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MISPSTTHNQPIQPELDLHLLSAVLLLLGLGLVMVYSASIAIAESKYGEGGTYYFLVRQALSILLGIFAGMVAFQVSLRQ
WQTYSHYLLAIGIVLLTVVLIPGIGLEINGSRRWLPLVIFNFQPSELMKLLILIFTADYVVRKTAYKDHFFKGFLPILTL
LAIVSLLLLMEPDLGAAVIIAAIVLSIMFINGMSLKMFLGLLCLIPIPLILLIIFEPYRMDRINAIFDPWNDPFNKGYQL
THALIAFGLGEWWGVGLGGSVEKLNYLPEAHTDFMFAVLAEELGFAGVATVIALFFFLLIRTFRIGRAAATQGDQFGALV
AQGIGVWLGFQAFINMGVNMGLLPTKGLTLPFMSYGGSSIVINSIAIAILLRIDWENRQKRRGLNV

Sequences:

>Translated_386_residues
MISPSTTHNQPIQPELDLHLLSAVLLLLGLGLVMVYSASIAIAESKYGEGGTYYFLVRQALSILLGIFAGMVAFQVSLRQ
WQTYSHYLLAIGIVLLTVVLIPGIGLEINGSRRWLPLVIFNFQPSELMKLLILIFTADYVVRKTAYKDHFFKGFLPILTL
LAIVSLLLLMEPDLGAAVIIAAIVLSIMFINGMSLKMFLGLLCLIPIPLILLIIFEPYRMDRINAIFDPWNDPFNKGYQL
THALIAFGLGEWWGVGLGGSVEKLNYLPEAHTDFMFAVLAEELGFAGVATVIALFFFLLIRTFRIGRAAATQGDQFGALV
AQGIGVWLGFQAFINMGVNMGLLPTKGLTLPFMSYGGSSIVINSIAIAILLRIDWENRQKRRGLNV
>Mature_386_residues
MISPSTTHNQPIQPELDLHLLSAVLLLLGLGLVMVYSASIAIAESKYGEGGTYYFLVRQALSILLGIFAGMVAFQVSLRQ
WQTYSHYLLAIGIVLLTVVLIPGIGLEINGSRRWLPLVIFNFQPSELMKLLILIFTADYVVRKTAYKDHFFKGFLPILTL
LAIVSLLLLMEPDLGAAVIIAAIVLSIMFINGMSLKMFLGLLCLIPIPLILLIIFEPYRMDRINAIFDPWNDPFNKGYQL
THALIAFGLGEWWGVGLGGSVEKLNYLPEAHTDFMFAVLAEELGFAGVATVIALFFFLLIRTFRIGRAAATQGDQFGALV
AQGIGVWLGFQAFINMGVNMGLLPTKGLTLPFMSYGGSSIVINSIAIAILLRIDWENRQKRRGLNV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=365, Percent_Identity=41.3698630136986, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1786853, Length=347, Percent_Identity=32.5648414985591, Blast_Score=148, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42599; Mature: 42599

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISPSTTHNQPIQPELDLHLLSAVLLLLGLGLVMVYSASIAIAESKYGEGGTYYFLVRQA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHH
LSILLGIFAGMVAFQVSLRQWQTYSHYLLAIGIVLLTVVLIPGIGLEINGSRRWLPLVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEE
NFQPSELMKLLILIFTADYVVRKTAYKDHFFKGFLPILTLLAIVSLLLLMEPDLGAAVII
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AAIVLSIMFINGMSLKMFLGLLCLIPIPLILLIIFEPYRMDRINAIFDPWNDPFNKGYQL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHCCHHH
THALIAFGLGEWWGVGLGGSVEKLNYLPEAHTDFMFAVLAEELGFAGVATVIALFFFLLI
HHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RTFRIGRAAATQGDQFGALVAQGIGVWLGFQAFINMGVNMGLLPTKGLTLPFMSYGGSSI
HHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCHH
VINSIAIAILLRIDWENRQKRRGLNV
HHHHHHHHHHEEECCCCHHHHCCCCC
>Mature Secondary Structure
MISPSTTHNQPIQPELDLHLLSAVLLLLGLGLVMVYSASIAIAESKYGEGGTYYFLVRQA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHH
LSILLGIFAGMVAFQVSLRQWQTYSHYLLAIGIVLLTVVLIPGIGLEINGSRRWLPLVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEE
NFQPSELMKLLILIFTADYVVRKTAYKDHFFKGFLPILTLLAIVSLLLLMEPDLGAAVII
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AAIVLSIMFINGMSLKMFLGLLCLIPIPLILLIIFEPYRMDRINAIFDPWNDPFNKGYQL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHCCHHH
THALIAFGLGEWWGVGLGGSVEKLNYLPEAHTDFMFAVLAEELGFAGVATVIALFFFLLI
HHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RTFRIGRAAATQGDQFGALVAQGIGVWLGFQAFINMGVNMGLLPTKGLTLPFMSYGGSSI
HHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCHH
VINSIAIAILLRIDWENRQKRRGLNV
HHHHHHHHHHEEECCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]