Click here to switch to the map view.

The map label for this gene is murG [H]

Identifier: 114330273

GI number: 114330273

Start: 259026

End: 260138

Strand: Reverse

Name: murG [H]

Synonym: Neut_0246

Alternate gene names: 114330273

Gene position: 260138-259026 (Counterclockwise)

Preceding gene: 114330274

Following gene: 114330272

Centisome position: 9.78

GC content: 52.38

Gene sequence:

>1113_bases
ATGGCATACACCACATGTGGAGTTCACAGCTTGTCCCGCACAATCATGATCATGGCAGGGGGAACCGGTGGACATGTATT
TCCGGGGCTTGCGGTAGCTCGTGCCATGCAGGCTGAGGGCTGGCGAGTTATCTGGCTGGGTACTCGTAATGGCATGGAGG
CCACATTGGTACCACAACATGGTTTTACTATTGAGCTGATCAATTTTTCCGGGCTGCGCGGCAAAAAACCGGTCAGCTAT
TTGTTGCTCCCCTGGAGATTGGCAAAAGCCTGCTGGCAAAGTTTCTGCATATTGCGTCGCCAACGCCCGCAGATTGTACT
CGGGATGGGAGGTTACCCGGCGCTTCCTGGAGGGATAATGGCTGTTTTGTCTGGCAAGCCGTTGCTGATTCATGAGCAAA
ACAGAATCGCGGGACTAACCAATAAAATACTGGCAAAAATTGCCAGCCGTATCCTGCTGGCATTTCCCGGTACCATCACG
GACCAGGCAGGCAAGATTCAGGTTACCGGCAATCCGGTACGAACAGAGATCGCGCAGCTCCCGTCACCGGAAGTGCGTTA
TGCAAAACGGGCAGGCAAGCTGAACATCCTGGTGGTGGGCGGCAGCCTTGGTGCACAGGCATTAAATACCGTGCTGCCAC
AGGCTTTGAGCATGATTCCTGGAAATCAGCGGCCATTTGTTACCCACCAGTCCGGAAAAGTTCATCTGGCTGCGTTGCAG
CAAGCTTACGCTGAGCATGGTGTCACAGGTAATCTGGTCGCATTCATTGAGGATATGGCTGTGTATTACCAGAATTGTGA
TCTGGTAGTTTGTCGCGCTGGCGCGCTAACGATTGCTGAACTGGCTGCGGCAGGAGTAGCCAGTATTCTGGTGCCTTACC
CCTACGCAGTGGATGATCATCAGACGGCTAATGCGCGATTTTTGAGTGAACACCATGCTGCTGTTTTATGGCCTCAATCC
GAACTGACCGCAAACTCACTTGCACAATGGCTGATGACTTGTACACGCACACAACTGCAAACAATGGCAATCAATGCACG
CATGCTGGCCATGCCTGAAGCTGCACAAAGCGTAGTCACAGTTTGTCAACAACTTATTGAGACAGGCCCATGA

Upstream 100 bases:

>100_bases
ATCAACAGTATTGCAATTGCCATATTGCTGCGGATTGATTGGGAAAATCGGCAAAAACGCAGAGGGCTAAATGTATGAAT
AAACACCTGCAATCCGGTCC

Downstream 100 bases:

>100_bases
AACATAAAATCAAGCATATTCATTTTGTAGGGATTGGTGGTTCGGGAATGGGCGGGATTGCTGAGGTGCTGATCAATCAA
GGCTTCCAGATCAGCGGCTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MAYTTCGVHSLSRTIMIMAGGTGGHVFPGLAVARAMQAEGWRVIWLGTRNGMEATLVPQHGFTIELINFSGLRGKKPVSY
LLLPWRLAKACWQSFCILRRQRPQIVLGMGGYPALPGGIMAVLSGKPLLIHEQNRIAGLTNKILAKIASRILLAFPGTIT
DQAGKIQVTGNPVRTEIAQLPSPEVRYAKRAGKLNILVVGGSLGAQALNTVLPQALSMIPGNQRPFVTHQSGKVHLAALQ
QAYAEHGVTGNLVAFIEDMAVYYQNCDLVVCRAGALTIAELAAAGVASILVPYPYAVDDHQTANARFLSEHHAAVLWPQS
ELTANSLAQWLMTCTRTQLQTMAINARMLAMPEAAQSVVTVCQQLIETGP

Sequences:

>Translated_370_residues
MAYTTCGVHSLSRTIMIMAGGTGGHVFPGLAVARAMQAEGWRVIWLGTRNGMEATLVPQHGFTIELINFSGLRGKKPVSY
LLLPWRLAKACWQSFCILRRQRPQIVLGMGGYPALPGGIMAVLSGKPLLIHEQNRIAGLTNKILAKIASRILLAFPGTIT
DQAGKIQVTGNPVRTEIAQLPSPEVRYAKRAGKLNILVVGGSLGAQALNTVLPQALSMIPGNQRPFVTHQSGKVHLAALQ
QAYAEHGVTGNLVAFIEDMAVYYQNCDLVVCRAGALTIAELAAAGVASILVPYPYAVDDHQTANARFLSEHHAAVLWPQS
ELTANSLAQWLMTCTRTQLQTMAINARMLAMPEAAQSVVTVCQQLIETGP
>Mature_369_residues
AYTTCGVHSLSRTIMIMAGGTGGHVFPGLAVARAMQAEGWRVIWLGTRNGMEATLVPQHGFTIELINFSGLRGKKPVSYL
LLPWRLAKACWQSFCILRRQRPQIVLGMGGYPALPGGIMAVLSGKPLLIHEQNRIAGLTNKILAKIASRILLAFPGTITD
QAGKIQVTGNPVRTEIAQLPSPEVRYAKRAGKLNILVVGGSLGAQALNTVLPQALSMIPGNQRPFVTHQSGKVHLAALQQ
AYAEHGVTGNLVAFIEDMAVYYQNCDLVVCRAGALTIAELAAAGVASILVPYPYAVDDHQTANARFLSEHHAAVLWPQSE
LTANSLAQWLMTCTRTQLQTMAINARMLAMPEAAQSVVTVCQQLIETGP

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=347, Percent_Identity=46.3976945244957, Blast_Score=291, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39759; Mature: 39628

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYTTCGVHSLSRTIMIMAGGTGGHVFPGLAVARAMQAEGWRVIWLGTRNGMEATLVPQH
CCEEECCHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCC
GFTIELINFSGLRGKKPVSYLLLPWRLAKACWQSFCILRRQRPQIVLGMGGYPALPGGIM
CCEEEEEEECCCCCCCCHHEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHH
AVLSGKPLLIHEQNRIAGLTNKILAKIASRILLAFPGTITDQAGKIQVTGNPVRTEIAQL
HEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHC
PSPEVRYAKRAGKLNILVVGGSLGAQALNTVLPQALSMIPGNQRPFVTHQSGKVHLAALQ
CCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEHHHHH
QAYAEHGVTGNLVAFIEDMAVYYQNCDLVVCRAGALTIAELAAAGVASILVPYPYAVDDH
HHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
QTANARFLSEHHAAVLWPQSELTANSLAQWLMTCTRTQLQTMAINARMLAMPEAAQSVVT
CCCCHHHHHCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHEECEEEEECCHHHHHHHH
VCQQLIETGP
HHHHHHHCCC
>Mature Secondary Structure 
AYTTCGVHSLSRTIMIMAGGTGGHVFPGLAVARAMQAEGWRVIWLGTRNGMEATLVPQH
CEEECCHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCC
GFTIELINFSGLRGKKPVSYLLLPWRLAKACWQSFCILRRQRPQIVLGMGGYPALPGGIM
CCEEEEEEECCCCCCCCHHEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHH
AVLSGKPLLIHEQNRIAGLTNKILAKIASRILLAFPGTITDQAGKIQVTGNPVRTEIAQL
HEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHC
PSPEVRYAKRAGKLNILVVGGSLGAQALNTVLPQALSMIPGNQRPFVTHQSGKVHLAALQ
CCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEHHHHH
QAYAEHGVTGNLVAFIEDMAVYYQNCDLVVCRAGALTIAELAAAGVASILVPYPYAVDDH
HHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
QTANARFLSEHHAAVLWPQSELTANSLAQWLMTCTRTQLQTMAINARMLAMPEAAQSVVT
CCCCHHHHHCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHEECEEEEECCHHHHHHHH
VCQQLIETGP
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA