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The map label for this gene is ubiB [C]

Identifier: 114330211

GI number: 114330211

Start: 181673

End: 183757

Strand: Reverse

Name: ubiB [C]

Synonym: Neut_0182

Alternate gene names: 114330211

Gene position: 183757-181673 (Counterclockwise)

Preceding gene: 114330216

Following gene: 114330210

Centisome position: 6.91

GC content: 54.63

Gene sequence:

>2085_bases
ATGAAAAATCATCTGGAGAGTAAAGTCATAAAACGCGTGATGGTAGGCACCGACCGCTCTGAAGCCGCCGACCGAGCTGT
CCAGTGGGCCGCTGGATTTGCCGACCGCTACGATGCGGAGCTGTTCGCGGTTGAGGTAGTGGTGCCGCAGTATCCGTCCG
CCACAGAATTCGGCGAAGCCGAACAAACGCGCGCTGCGGCAGCCAACAACGATTTGGCACACTTTGTGCGGCAGGTCGCC
GGAGATCGCGGGCATGCTTTGGTCGTCATTGATACGGATCCGGCATTGGCAATCGTCCGCGCCGCTGAACAGAAGGCAGT
CGATGTCCTGGTGGTTGGCAATTTTGGCATGGCAGGTCGAAAAAAGTTTTTGCTCGGTAACATACCGAACCGCATCAGTC
ATAGTGCCCATTGCACCGTGATTATTGTAAATACCGCGCATTCTACTGGTGAGCAGACATCGGGTTTGGCTCGAACTCAC
CTATCCGAGGGTGAAATCCCGCCTTTTGAGCCTCGACTGGCAGCCCGCGCTACGCATATCGCAGCTGTAATGGCGAAACA
TGGCCTCAAGCTGTTCAGCCAGTCTAACGAACCAGATATATCTATCCGCCGTCAGCAAGCCAAGCGCTTACGAGCAGCCC
TGGAAGAGCTTGGCCCGATATTCTCAAAACTCGGACAAGTGTTGTCAACTCGCCCGGATCTCCTTCCAATTGAATACATT
GAGGAGCTTTCTCTGTTGCAGTCCCGGGTGCCGCCGATGACGGAAAGCGAGGTGGTCCAAGTTTCCGAGCAGGAATTGAG
AGTCCCCTGGGAGGATGTATTCAAGTCGATTGACCCGAAGCCTCTCGCCGCTGGCACGATCGCTCAGGTCCATCGTGCAA
CGCTCGAAAGCGGTGAACGGGTCGTAGTCAAGGTTCAGCGACCGACTGCTCGCATGGATATCGAACAGGATCTCGCCCTC
CTCCAGGTGTTTGTGGAGAAAGTCGGAAAGCGTCCTGCGCTCAATCAGGTGATTGATATGGAAGCCGTGTTCAAACATCT
CTCCACCTCGCTCCATAGTGAACTCGACTTCCGTCAGGAGGCCGACAATATCGAGCGCATGCAAGTGGTGCTCGCAGACT
ATAATCGCCTTGCCGTACCCAGCGTACACCGGGATCTGTCCACGTCTCGGTTATTAGTAATGGAAGAGATCCAGGGTATA
CCGATCAGGCAGGCGCCGGCTGGCCCAGCACGCATCCAGGCTGCTCGTCAACTGTTGGAGAGCTACTACAAACAGATCAT
CGTCGATGGCTTCTTCCATGCCGATCCCCACCCAGGCAATCTGATGTGGTGGAAGGATTGCATCTATTTTCTTGATTTCG
GAATGGTCGGTATGGTAGGAACCGATCTCCGTGAGCATCTCTTGTTAATGTTGATGGCTCTATGGCAGGAAGATGCGGCG
TTTCTCACCGATGTCACATTCATGATGACGAGCGCCGATAATAGTAGCACCCTCGATGTGGCCCGATTCCAGAGTGAGAT
TGGGGAAGTGATGGCAAAATATCGCACTGCCTCGCTTGCCGAGATGCAGATCGGGCCGCTTCTGCAAGAAATGAGTGCGG
TTTCGTTACGGCACGGAGTACCGCTACCAGCTTCGCTCACGCTCGCCATCAAGGCACTCGCGCAGGTACAGCTGGCGACT
GCCGAGCTTGATCCAGCACTCGATCCGTATGACGTAGCGGGAAAGTATCTGATGCGCTTGATGGCTAAACGCATGGGTAC
CGCGTTCAATCCGAAGACATTGCTGTATCAATCTCAGAAGTTGAAAGTACGAACCCTGCGCATGATCGAAGCAGTTGAAA
ATTTCGTTGGTGCCCGCCCTGGCGGTCCAAAGCTTGTGGTAAATTTCCGGGCCAATTCACTGGAGGATATAGTACGTCAT
ACGGGACGACGACTAGCGCTCGGCCTGACCGCTGCGGCAAGTATCCTGGCCAGTGGATTCACAGCAGCGTCAACGGTTAC
TGCCGAGTGGGTGCCAATAACATTCGGGATCGTCGGAGGTCTGCTGACCCTTGGCCTGGTTATCGATCTGCTGCAAAGAC
ATTGA

Upstream 100 bases:

>100_bases
AGCACGCTGATAAGCGTTTGGGCAGGGTGTTTGCACACCCTGCCACCCAGGCTGATCCTGTCATATCGATGCTATCCCTG
CTCATCACTCTACAACATTT

Downstream 100 bases:

>100_bases
AGACAAAAATAGTTTACGATGGCGGACTGTTCAGTGCCGAAGATTTTGTGCCACTACGCTTGATCGAACGCAACACGGCT
TTCTCGATCACGTAGGCGAT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MKNHLESKVIKRVMVGTDRSEAADRAVQWAAGFADRYDAELFAVEVVVPQYPSATEFGEAEQTRAAAANNDLAHFVRQVA
GDRGHALVVIDTDPALAIVRAAEQKAVDVLVVGNFGMAGRKKFLLGNIPNRISHSAHCTVIIVNTAHSTGEQTSGLARTH
LSEGEIPPFEPRLAARATHIAAVMAKHGLKLFSQSNEPDISIRRQQAKRLRAALEELGPIFSKLGQVLSTRPDLLPIEYI
EELSLLQSRVPPMTESEVVQVSEQELRVPWEDVFKSIDPKPLAAGTIAQVHRATLESGERVVVKVQRPTARMDIEQDLAL
LQVFVEKVGKRPALNQVIDMEAVFKHLSTSLHSELDFRQEADNIERMQVVLADYNRLAVPSVHRDLSTSRLLVMEEIQGI
PIRQAPAGPARIQAARQLLESYYKQIIVDGFFHADPHPGNLMWWKDCIYFLDFGMVGMVGTDLREHLLLMLMALWQEDAA
FLTDVTFMMTSADNSSTLDVARFQSEIGEVMAKYRTASLAEMQIGPLLQEMSAVSLRHGVPLPASLTLAIKALAQVQLAT
AELDPALDPYDVAGKYLMRLMAKRMGTAFNPKTLLYQSQKLKVRTLRMIEAVENFVGARPGGPKLVVNFRANSLEDIVRH
TGRRLALGLTAAASILASGFTAASTVTAEWVPITFGIVGGLLTLGLVIDLLQRH

Sequences:

>Translated_694_residues
MKNHLESKVIKRVMVGTDRSEAADRAVQWAAGFADRYDAELFAVEVVVPQYPSATEFGEAEQTRAAAANNDLAHFVRQVA
GDRGHALVVIDTDPALAIVRAAEQKAVDVLVVGNFGMAGRKKFLLGNIPNRISHSAHCTVIIVNTAHSTGEQTSGLARTH
LSEGEIPPFEPRLAARATHIAAVMAKHGLKLFSQSNEPDISIRRQQAKRLRAALEELGPIFSKLGQVLSTRPDLLPIEYI
EELSLLQSRVPPMTESEVVQVSEQELRVPWEDVFKSIDPKPLAAGTIAQVHRATLESGERVVVKVQRPTARMDIEQDLAL
LQVFVEKVGKRPALNQVIDMEAVFKHLSTSLHSELDFRQEADNIERMQVVLADYNRLAVPSVHRDLSTSRLLVMEEIQGI
PIRQAPAGPARIQAARQLLESYYKQIIVDGFFHADPHPGNLMWWKDCIYFLDFGMVGMVGTDLREHLLLMLMALWQEDAA
FLTDVTFMMTSADNSSTLDVARFQSEIGEVMAKYRTASLAEMQIGPLLQEMSAVSLRHGVPLPASLTLAIKALAQVQLAT
AELDPALDPYDVAGKYLMRLMAKRMGTAFNPKTLLYQSQKLKVRTLRMIEAVENFVGARPGGPKLVVNFRANSLEDIVRH
TGRRLALGLTAAASILASGFTAASTVTAEWVPITFGIVGGLLTLGLVIDLLQRH
>Mature_694_residues
MKNHLESKVIKRVMVGTDRSEAADRAVQWAAGFADRYDAELFAVEVVVPQYPSATEFGEAEQTRAAAANNDLAHFVRQVA
GDRGHALVVIDTDPALAIVRAAEQKAVDVLVVGNFGMAGRKKFLLGNIPNRISHSAHCTVIIVNTAHSTGEQTSGLARTH
LSEGEIPPFEPRLAARATHIAAVMAKHGLKLFSQSNEPDISIRRQQAKRLRAALEELGPIFSKLGQVLSTRPDLLPIEYI
EELSLLQSRVPPMTESEVVQVSEQELRVPWEDVFKSIDPKPLAAGTIAQVHRATLESGERVVVKVQRPTARMDIEQDLAL
LQVFVEKVGKRPALNQVIDMEAVFKHLSTSLHSELDFRQEADNIERMQVVLADYNRLAVPSVHRDLSTSRLLVMEEIQGI
PIRQAPAGPARIQAARQLLESYYKQIIVDGFFHADPHPGNLMWWKDCIYFLDFGMVGMVGTDLREHLLLMLMALWQEDAA
FLTDVTFMMTSADNSSTLDVARFQSEIGEVMAKYRTASLAEMQIGPLLQEMSAVSLRHGVPLPASLTLAIKALAQVQLAT
AELDPALDPYDVAGKYLMRLMAKRMGTAFNPKTLLYQSQKLKVRTLRMIEAVENFVGARPGGPKLVVNFRANSLEDIVRH
TGRRLALGLTAAASILASGFTAASTVTAEWVPITFGIVGGLLTLGLVIDLLQRH

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=266, Percent_Identity=34.2105263157895, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI41393593, Length=229, Percent_Identity=32.3144104803493, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI217035081, Length=222, Percent_Identity=33.7837837837838, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI27363457, Length=354, Percent_Identity=26.271186440678, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI217416386, Length=354, Percent_Identity=26.271186440678, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI34147522, Length=242, Percent_Identity=23.9669421487603, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367309, Length=503, Percent_Identity=28.2306163021869, Blast_Score=146, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17559152, Length=296, Percent_Identity=29.3918918918919, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32565180, Length=309, Percent_Identity=25.5663430420712, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321319, Length=237, Percent_Identity=28.2700421940928, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6325148, Length=256, Percent_Identity=26.171875, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323282, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24662575, Length=346, Percent_Identity=29.4797687861272, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI22024280, Length=229, Percent_Identity=29.6943231441048, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI18859849, Length=241, Percent_Identity=26.9709543568465, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 76429; Mature: 76429

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHLESKVIKRVMVGTDRSEAADRAVQWAAGFADRYDAELFAVEVVVPQYPSATEFGEA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCCEEEEEEEEECCCCCCCCCCCH
EQTRAAAANNDLAHFVRQVAGDRGHALVVIDTDPALAIVRAAEQKAVDVLVVGNFGMAGR
HHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEEECCCCCCC
KKFLLGNIPNRISHSAHCTVIIVNTAHSTGEQTSGLARTHLSEGEIPPFEPRLAARATHI
CHHHCCCCCHHHCCCCCEEEEEEECCCCCCCHHCCHHHHCCCCCCCCCCCCHHHHHHHHH
AAVMAKHGLKLFSQSNEPDISIRRQQAKRLRAALEELGPIFSKLGQVLSTRPDLLPIEYI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
EELSLLQSRVPPMTESEVVQVSEQELRVPWEDVFKSIDPKPLAAGTIAQVHRATLESGER
HHHHHHHHCCCCCCHHHHHHHCHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCE
VVVKVQRPTARMDIEQDLALLQVFVEKVGKRPALNQVIDMEAVFKHLSTSLHSELDFRQE
EEEEEECCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADNIERMQVVLADYNRLAVPSVHRDLSTSRLLVMEEIQGIPIRQAPAGPARIQAARQLLE
HHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SYYKQIIVDGFFHADPHPGNLMWWKDCIYFLDFGMVGMVGTDLREHLLLMLMALWQEDAA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FLTDVTFMMTSADNSSTLDVARFQSEIGEVMAKYRTASLAEMQIGPLLQEMSAVSLRHGV
HHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLPASLTLAIKALAQVQLATAELDPALDPYDVAGKYLMRLMAKRMGTAFNPKTLLYQSQK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEECCC
LKVRTLRMIEAVENFVGARPGGPKLVVNFRANSLEDIVRHTGRRLALGLTAAASILASGF
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCEEEHHHHHHHHHHHCCC
TAASTVTAEWVPITFGIVGGLLTLGLVIDLLQRH
HHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNHLESKVIKRVMVGTDRSEAADRAVQWAAGFADRYDAELFAVEVVVPQYPSATEFGEA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCCEEEEEEEEECCCCCCCCCCCH
EQTRAAAANNDLAHFVRQVAGDRGHALVVIDTDPALAIVRAAEQKAVDVLVVGNFGMAGR
HHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEEECCCCCCC
KKFLLGNIPNRISHSAHCTVIIVNTAHSTGEQTSGLARTHLSEGEIPPFEPRLAARATHI
CHHHCCCCCHHHCCCCCEEEEEEECCCCCCCHHCCHHHHCCCCCCCCCCCCHHHHHHHHH
AAVMAKHGLKLFSQSNEPDISIRRQQAKRLRAALEELGPIFSKLGQVLSTRPDLLPIEYI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
EELSLLQSRVPPMTESEVVQVSEQELRVPWEDVFKSIDPKPLAAGTIAQVHRATLESGER
HHHHHHHHCCCCCCHHHHHHHCHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCE
VVVKVQRPTARMDIEQDLALLQVFVEKVGKRPALNQVIDMEAVFKHLSTSLHSELDFRQE
EEEEEECCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADNIERMQVVLADYNRLAVPSVHRDLSTSRLLVMEEIQGIPIRQAPAGPARIQAARQLLE
HHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SYYKQIIVDGFFHADPHPGNLMWWKDCIYFLDFGMVGMVGTDLREHLLLMLMALWQEDAA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FLTDVTFMMTSADNSSTLDVARFQSEIGEVMAKYRTASLAEMQIGPLLQEMSAVSLRHGV
HHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLPASLTLAIKALAQVQLATAELDPALDPYDVAGKYLMRLMAKRMGTAFNPKTLLYQSQK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEECCC
LKVRTLRMIEAVENFVGARPGGPKLVVNFRANSLEDIVRHTGRRLALGLTAAASILASGF
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCEEEHHHHHHHHHHHCCC
TAASTVTAEWVPITFGIVGGLLTLGLVIDLLQRH
HHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA