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The map label for this gene is insK [C]

Identifier: 114330049

GI number: 114330049

Start: 14163

End: 15014

Strand: Direct

Name: insK [C]

Synonym: Neut_0013

Alternate gene names: 114330049

Gene position: 14163-15014 (Clockwise)

Preceding gene: 114330048

Following gene: 114330051

Centisome position: 0.53

GC content: 60.56

Gene sequence:

>852_bases
GTGTTGCAGGTTGCCCCATCGGCGTATCGGCGTCATGCCGCCCGCCAACGATGCCCGAAACTGCGCAGTGCGCGCAGCCA
GCGCGACGAGGGTTTGATGGCCGAGATTCGGCGTGTCTGGCAAGCCAACATGCAGGTCTACGGCGTACGCAAGGTATGGT
ACCAGTTGCAACGCGAAGGCATTGCCGTGGCTCGCTGCACGGTTGAACGCCTGATGCGTCGCCTGGGTTTGCAGGGCGTG
CGCCGGGGCAAGCGGGTGCGCACCACCATTGCCGACGGTTCGCAGGCATGCTCACTGGATCGCGTCAATCGCCACTTCCA
TGCCGACAGGCCCAATCAGTTATGGGTCTCGGACTTCACCTACGTGTCGACCTGGCAAGGCTGGCTGTATGTGGCCTTCG
TCATCGACGTGTTTGCCCGGCGCATCGTCGGCTGGCGCGTGAGCACCACCATGAGTACAGACTTCGTGCTCGATGCTCTG
GAGCAGGCTCTGTATGACCGGCGTCCCGCCGAGTCTCTGATTCACCATTCCGATCGAGGATCGCAATACGTGTCCATCCG
CTACACCGAACGCCTGGCCGAGGCAGGCATCGAACCGTCGGTGGGCAGCCGTGGCGACAGTTACGACAATGCCCTGGCTG
AAACCATTAACGGGCTGTACAAGGCCGAACTGATTCATCGCCGAGCGCCCTGGAAAACCAGGGCTGCTGTGGAATTGGCA
ACGTTGGAATGGGTCGCCTGGTACAACCATCAGCGTCTGCTCGGGTCCATCGGGTATATTCCTCCTGCGCAGGCTGAAGA
ACTCTATCACCGTACCCACTCTGAAACTGTGCCGATGAACGCTGTACTTTAA

Upstream 100 bases:

>100_bases
GTGCTTTTTTCGCCCAGGCGGCGCTCGACCGCGAACTGAAGAAGTAAACGCCTATATCGACCGGCACCGGGACGTCTACG
GGGTCGAGCCGATCTGCAAG

Downstream 100 bases:

>100_bases
CCAAACAGCCTCCTCGATTCCCGGGGCGATTCACCCAACCATCTTTATAGTAAACAAATAGAGGATAAAACAAACGATTC
AAAACCATGAATTCCTAGCA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLQVAPSAYRRHAARQRCPKLRSARSQRDEGLMAEIRRVWQANMQVYGVRKVWYQLQREGIAVARCTVERLMRRLGLQGV
RRGKRVRTTIADGSQACSLDRVNRHFHADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWRVSTTMSTDFVLDAL
EQALYDRRPAESLIHHSDRGSQYVSIRYTERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRAAVELA
TLEWVAWYNHQRLLGSIGYIPPAQAEELYHRTHSETVPMNAVL

Sequences:

>Translated_283_residues
MLQVAPSAYRRHAARQRCPKLRSARSQRDEGLMAEIRRVWQANMQVYGVRKVWYQLQREGIAVARCTVERLMRRLGLQGV
RRGKRVRTTIADGSQACSLDRVNRHFHADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWRVSTTMSTDFVLDAL
EQALYDRRPAESLIHHSDRGSQYVSIRYTERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRAAVELA
TLEWVAWYNHQRLLGSIGYIPPAQAEELYHRTHSETVPMNAVL
>Mature_283_residues
MLQVAPSAYRRHAARQRCPKLRSARSQRDEGLMAEIRRVWQANMQVYGVRKVWYQLQREGIAVARCTVERLMRRLGLQGV
RRGKRVRTTIADGSQACSLDRVNRHFHADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWRVSTTMSTDFVLDAL
EQALYDRRPAESLIHHSDRGSQYVSIRYTERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRAAVELA
TLEWVAWYNHQRLLGSIGYIPPAQAEELYHRTHSETVPMNAVL

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=241, Percent_Identity=56.0165975103734, Blast_Score=268, Evalue=4e-72,
Organism=Escherichia coli, GI1789981, Length=229, Percent_Identity=30.5676855895196, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788405, Length=182, Percent_Identity=34.6153846153846, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787263, Length=182, Percent_Identity=34.6153846153846, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786753, Length=182, Percent_Identity=34.6153846153846, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786570, Length=182, Percent_Identity=34.6153846153846, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786490, Length=182, Percent_Identity=34.6153846153846, Blast_Score=114, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32669; Mature: 32669

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVAPSAYRRHAARQRCPKLRSARSQRDEGLMAEIRRVWQANMQVYGVRKVWYQLQREG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
IAVARCTVERLMRRLGLQGVRRGKRVRTTIADGSQACSLDRVNRHFHADRPNQLWVSDFT
HHHHHHHHHHHHHHHCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCEEECCCH
YVSTWQGWLYVAFVIDVFARRIVGWRVSTTMSTDFVLDALEQALYDRRPAESLIHHSDRG
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCC
SQYVSIRYTERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRAAVELA
CEEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
TLEWVAWYNHQRLLGSIGYIPPAQAEELYHRTHSETVPMNAVL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLQVAPSAYRRHAARQRCPKLRSARSQRDEGLMAEIRRVWQANMQVYGVRKVWYQLQREG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
IAVARCTVERLMRRLGLQGVRRGKRVRTTIADGSQACSLDRVNRHFHADRPNQLWVSDFT
HHHHHHHHHHHHHHHCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCEEECCCH
YVSTWQGWLYVAFVIDVFARRIVGWRVSTTMSTDFVLDALEQALYDRRPAESLIHHSDRG
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCC
SQYVSIRYTERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRAAVELA
CEEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
TLEWVAWYNHQRLLGSIGYIPPAQAEELYHRTHSETVPMNAVL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]