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The map label for this gene is ucpA [C]

Identifier: 113969958

GI number: 113969958

Start: 1914589

End: 1915542

Strand: Direct

Name: ucpA [C]

Synonym: Shewmr4_1618

Alternate gene names: 113969958

Gene position: 1914589-1915542 (Clockwise)

Preceding gene: 113969956

Following gene: 113969959

Centisome position: 40.68

GC content: 50.63

Gene sequence:

>954_bases
ATGCGTTTCGATAATCGAGTGGCGTTGGTAACGGGAGCAGGCTCCGGGCTAGGGAGAGCCTATGCCATTATGTTGGCTGA
GCGGGGCGCCAAACTGGTATTAGTTGACCAACCTAAGGGAAGTCCATCCCAAGGCGAGGCATTGAGGGCAACTAGCTCTT
CTAACTTAACTCATGCAACTAACGCAGAGCTGCAGCAAACCCATCAGGCCATTTTAAAGCTTGGGGGAGAATGCCTGTAT
TTTGAAGTAGATGTTAGCCAGCAGGATGATGTCAAGGTGATGGTGAATCGTCTACAGCAAGATTGGCAACGCGTGGATAT
TTTGATCAATAACGCAGGGGTTTACGGCGCGTGCTCCTTCGAGCATATCCAACAAGCCGACTGGCAGCGACAGTTTCATG
TGGATGTGAACGGCAGTTTTTATCTTACTCAGGCCCTGTGGCCGCTGATGAAGACCCATGGTTATGGCCGAATTTTGATG
ACCACGGGGGTGTCGGCGTTGTTTGGCGACTTACATCAGGTTCCGTTCAGCGCTGCCAAGATGGCTCTCGTCGGTATGGT
GAATAGCCTTTCCTTAGAGGGCGAGCAGTATAACATCCATATCAATAGCCTGTGCCCGCAGGCACTCACGGCCATGACCG
ATAAACACTTAGCCCCAGCGATTCAACCGCTTTTTTCCTTTGATACTGTCACGGCGACTATGGCATTTTTAGTCAGTGGT
GCTGCGCCTAATGGCCAGCATCTGCTCGCGGGGGCGGGCAGTGTGAGTCATGGGATGTTTGCCGAATTTCAGTCCATCTA
TTTCAGTGAGGGGCTGTGTACACCTGATAAACTGGTCAAGTACTGGCCCGAGTTGCATTATGCCTTTCCGATTAATTTGC
ATACCTGCGGCGAAGATAAAGTGCTGGCTTGGTCAAAACAGAGTGCCCTTGAGCATCATATTAAAATTGAGTAG

Upstream 100 bases:

>100_bases
GCCGATGAACTTCACCCCTATTTTTGCAATAACCAGAGCTGTGAGGTGAAAGGTTTAGTGTGGCGTTTAGCGTGAATGTC
AATGATAAGGATACGATAGG

Downstream 100 bases:

>100_bases
TGCTTTGGGCGTGCTGAAGCTACAAGATGCAATAAGCTATCGACTCTCTACTGGTCAGCCCTAGTCTAACTGAGTTACCC
TTGGGCATTAGTTGCTAATT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MRFDNRVALVTGAGSGLGRAYAIMLAERGAKLVLVDQPKGSPSQGEALRATSSSNLTHATNAELQQTHQAILKLGGECLY
FEVDVSQQDDVKVMVNRLQQDWQRVDILINNAGVYGACSFEHIQQADWQRQFHVDVNGSFYLTQALWPLMKTHGYGRILM
TTGVSALFGDLHQVPFSAAKMALVGMVNSLSLEGEQYNIHINSLCPQALTAMTDKHLAPAIQPLFSFDTVTATMAFLVSG
AAPNGQHLLAGAGSVSHGMFAEFQSIYFSEGLCTPDKLVKYWPELHYAFPINLHTCGEDKVLAWSKQSALEHHIKIE

Sequences:

>Translated_317_residues
MRFDNRVALVTGAGSGLGRAYAIMLAERGAKLVLVDQPKGSPSQGEALRATSSSNLTHATNAELQQTHQAILKLGGECLY
FEVDVSQQDDVKVMVNRLQQDWQRVDILINNAGVYGACSFEHIQQADWQRQFHVDVNGSFYLTQALWPLMKTHGYGRILM
TTGVSALFGDLHQVPFSAAKMALVGMVNSLSLEGEQYNIHINSLCPQALTAMTDKHLAPAIQPLFSFDTVTATMAFLVSG
AAPNGQHLLAGAGSVSHGMFAEFQSIYFSEGLCTPDKLVKYWPELHYAFPINLHTCGEDKVLAWSKQSALEHHIKIE
>Mature_317_residues
MRFDNRVALVTGAGSGLGRAYAIMLAERGAKLVLVDQPKGSPSQGEALRATSSSNLTHATNAELQQTHQAILKLGGECLY
FEVDVSQQDDVKVMVNRLQQDWQRVDILINNAGVYGACSFEHIQQADWQRQFHVDVNGSFYLTQALWPLMKTHGYGRILM
TTGVSALFGDLHQVPFSAAKMALVGMVNSLSLEGEQYNIHINSLCPQALTAMTDKHLAPAIQPLFSFDTVTATMAFLVSG
AAPNGQHLLAGAGSVSHGMFAEFQSIYFSEGLCTPDKLVKYWPELHYAFPINLHTCGEDKVLAWSKQSALEHHIKIE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=229, Percent_Identity=36.6812227074236, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI210032110, Length=247, Percent_Identity=24.2914979757085, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=217, Percent_Identity=25.8064516129032, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4503817, Length=199, Percent_Identity=28.1407035175879, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI25282469, Length=231, Percent_Identity=26.8398268398268, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4758504, Length=212, Percent_Identity=28.3018867924528, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI142976729, Length=225, Percent_Identity=25.7777777777778, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32483357, Length=208, Percent_Identity=25.9615384615385, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40254992, Length=228, Percent_Identity=26.7543859649123, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI40807363, Length=236, Percent_Identity=23.728813559322, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI10190746, Length=242, Percent_Identity=26.0330578512397, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI223718074, Length=212, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI59889578, Length=129, Percent_Identity=26.3565891472868, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=208, Percent_Identity=29.3269230769231, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787905, Length=223, Percent_Identity=27.3542600896861, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787335, Length=207, Percent_Identity=27.536231884058, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788459, Length=262, Percent_Identity=25.9541984732824, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082160, Length=218, Percent_Identity=27.0642201834862, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789208, Length=205, Percent_Identity=22.4390243902439, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=205, Percent_Identity=29.7560975609756, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367175, Length=205, Percent_Identity=27.3170731707317, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790717, Length=200, Percent_Identity=22, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=292, Percent_Identity=33.2191780821918, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17564282, Length=206, Percent_Identity=24.2718446601942, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=219, Percent_Identity=29.2237442922374, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=211, Percent_Identity=26.0663507109005, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=222, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=239, Percent_Identity=24.2677824267782, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=231, Percent_Identity=29.4372294372294, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=225, Percent_Identity=23.1111111111111, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=222, Percent_Identity=27.9279279279279, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI86565303, Length=219, Percent_Identity=27.8538812785388, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=221, Percent_Identity=35.2941176470588, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI18859837, Length=254, Percent_Identity=34.6456692913386, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281364892, Length=191, Percent_Identity=28.2722513089005, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17737361, Length=216, Percent_Identity=27.3148148148148, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357041, Length=206, Percent_Identity=25.7281553398058, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21358495, Length=205, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640492, Length=207, Percent_Identity=21.7391304347826, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI23397609, Length=208, Percent_Identity=27.8846153846154, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28571526, Length=216, Percent_Identity=25.462962962963, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221510726, Length=179, Percent_Identity=27.9329608938547, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356301, Length=203, Percent_Identity=24.6305418719212, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34763; Mature: 34763

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDNRVALVTGAGSGLGRAYAIMLAERGAKLVLVDQPKGSPSQGEALRATSSSNLTHAT
CCCCCEEEEEEECCCCCCHHEEEEEECCCCEEEEEECCCCCCCCCCEEEECCCCCCEECC
NAELQQTHQAILKLGGECLYFEVDVSQQDDVKVMVNRLQQDWQRVDILINNAGVYGACSF
CHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCEEEECCH
EHIQQADWQRQFHVDVNGSFYLTQALWPLMKTHGYGRILMTTGVSALFGDLHQVPFSAAK
HHHHHCCCCEEEEEECCCCEEHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHH
MALVGMVNSLSLEGEQYNIHINSLCPQALTAMTDKHLAPAIQPLFSFDTVTATMAFLVSG
HHHHHHHHHEEECCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AAPNGQHLLAGAGSVSHGMFAEFQSIYFSEGLCTPDKLVKYWPELHYAFPINLHTCGEDK
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCC
VLAWSKQSALEHHIKIE
EEEECHHHHHHHCEECC
>Mature Secondary Structure
MRFDNRVALVTGAGSGLGRAYAIMLAERGAKLVLVDQPKGSPSQGEALRATSSSNLTHAT
CCCCCEEEEEEECCCCCCHHEEEEEECCCCEEEEEECCCCCCCCCCEEEECCCCCCEECC
NAELQQTHQAILKLGGECLYFEVDVSQQDDVKVMVNRLQQDWQRVDILINNAGVYGACSF
CHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCEEEECCH
EHIQQADWQRQFHVDVNGSFYLTQALWPLMKTHGYGRILMTTGVSALFGDLHQVPFSAAK
HHHHHCCCCEEEEEECCCCEEHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHH
MALVGMVNSLSLEGEQYNIHINSLCPQALTAMTDKHLAPAIQPLFSFDTVTATMAFLVSG
HHHHHHHHHEEECCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AAPNGQHLLAGAGSVSHGMFAEFQSIYFSEGLCTPDKLVKYWPELHYAFPINLHTCGEDK
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCC
VLAWSKQSALEHHIKIE
EEEECHHHHHHHCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]