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The map label for this gene is pdxH [H]

Identifier: 113969901

GI number: 113969901

Start: 1840909

End: 1841547

Strand: Direct

Name: pdxH [H]

Synonym: Shewmr4_1559

Alternate gene names: 113969901

Gene position: 1840909-1841547 (Clockwise)

Preceding gene: 113969900

Following gene: 113969902

Centisome position: 39.12

GC content: 51.64

Gene sequence:

>639_bases
ATGACAGATCTCAGTGATATTCGCCGCGAATACACCAAAGGCGGTCTAAGACGCGCCGATTTACCACAAAATCCCATGCA
GCTATTCGAGTTATGGATGACGCAAGCTCGCGATGCTGAGCTGAGCGATCCCACGGCGATGTGTGTTGCCACCGTCGATG
AGCATGGTCAGCCCTATCAGCGAATTGTGCTGTTAAAGCGCTTCGATGACTCGGGATTTGTGTTCTTCACTAACCTAGGT
AGCCGAAAAGCGCAGCAGATCGCAGCCAATAATAAGGTGAGTCTGCATTTTCCTTGGCATCCGATTGAACGCCAAGTATC
GATTCTCGGTGAGGCGCAGCCACTCTCTACCGCCGAAGTGCTGAAATACTTTATGACCCGTCCTAAGGATAGCCAGATAG
CCGCTTGGGTGTCACAGCAGTCGAGCAAACTGAGCGCGCGACAAGTACTCGAAGGTAAGTTCTTTGAAATGAAAGCCAAA
TTTGCCAAGGGCGATGTGCCCTTACCGAGCTTTTGGGGCGGCTACTTAGTTAAACCCTCGAGTATCGAGTTTTGGCAGGG
CGGGGAGCACAGGCTGCACGATCGTTTCCTCTACACTCGCCAAGCGGATGAATGGGTCATTGACCGTTTAGCACCTTAA

Upstream 100 bases:

>100_bases
GTAATAACAGAGCAGCGAATTGCGAGTAAGGCATGGTAAACTTGCATTATCAGCGGATTGCACCGATGGCAATCATTGTG
CGCTTGTAAAAGGAAACCCT

Downstream 100 bases:

>100_bases
TGGTCTTTAGGAGCGTAAGCGTGGGACAGTATAAGATTTGGGTCGATGCCGATGCCTGCCCAAACCCGATTAAAGAGATT
TTATTTCGCGCGGCAGAACG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTDLSDIRREYTKGGLRRADLPQNPMQLFELWMTQARDAELSDPTAMCVATVDEHGQPYQRIVLLKRFDDSGFVFFTNLG
SRKAQQIAANNKVSLHFPWHPIERQVSILGEAQPLSTAEVLKYFMTRPKDSQIAAWVSQQSSKLSARQVLEGKFFEMKAK
FAKGDVPLPSFWGGYLVKPSSIEFWQGGEHRLHDRFLYTRQADEWVIDRLAP

Sequences:

>Translated_212_residues
MTDLSDIRREYTKGGLRRADLPQNPMQLFELWMTQARDAELSDPTAMCVATVDEHGQPYQRIVLLKRFDDSGFVFFTNLG
SRKAQQIAANNKVSLHFPWHPIERQVSILGEAQPLSTAEVLKYFMTRPKDSQIAAWVSQQSSKLSARQVLEGKFFEMKAK
FAKGDVPLPSFWGGYLVKPSSIEFWQGGEHRLHDRFLYTRQADEWVIDRLAP
>Mature_211_residues
TDLSDIRREYTKGGLRRADLPQNPMQLFELWMTQARDAELSDPTAMCVATVDEHGQPYQRIVLLKRFDDSGFVFFTNLGS
RKAQQIAANNKVSLHFPWHPIERQVSILGEAQPLSTAEVLKYFMTRPKDSQIAAWVSQQSSKLSARQVLEGKFFEMKAKF
AKGDVPLPSFWGGYLVKPSSIEFWQGGEHRLHDRFLYTRQADEWVIDRLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=205, Percent_Identity=38.5365853658537, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1787926, Length=212, Percent_Identity=67.4528301886792, Blast_Score=313, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17553712, Length=220, Percent_Identity=32.7272727272727, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=36.8421052631579, Blast_Score=137, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24644901, Length=207, Percent_Identity=42.0289855072464, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45551845, Length=207, Percent_Identity=42.0289855072464, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24644903, Length=189, Percent_Identity=31.2169312169312, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24378; Mature: 24247

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSDIRREYTKGGLRRADLPQNPMQLFELWMTQARDAELSDPTAMCVATVDEHGQPYQ
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHH
RIVLLKRFDDSGFVFFTNLGSRKAQQIAANNKVSLHFPWHPIERQVSILGEAQPLSTAEV
HEEEEEEECCCCEEEEECCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHH
LKYFMTRPKDSQIAAWVSQQSSKLSARQVLEGKFFEMKAKFAKGDVPLPSFWGGYLVKPS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEECCC
SIEFWQGGEHRLHDRFLYTRQADEWVIDRLAP
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
TDLSDIRREYTKGGLRRADLPQNPMQLFELWMTQARDAELSDPTAMCVATVDEHGQPYQ
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHH
RIVLLKRFDDSGFVFFTNLGSRKAQQIAANNKVSLHFPWHPIERQVSILGEAQPLSTAEV
HEEEEEEECCCCEEEEECCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHH
LKYFMTRPKDSQIAAWVSQQSSKLSARQVLEGKFFEMKAKFAKGDVPLPSFWGGYLVKPS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEECCC
SIEFWQGGEHRLHDRFLYTRQADEWVIDRLAP
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA